CRISPR interference-guided multiplex repression of endogenous competing pathway genes for redirecting metabolic flux in Escherichia coli

Microbial Cell Factories

Volumn 16, Issue 1, 2017, Pages

  Kim, Seong Keun ^a   Seong, Wonjae ^a   Han, Gui Hwan ^a   Lee, Dae Hee ^a   Lee, Seung Goo ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

CRISPR interference; Endogenous gene; Escherichia coli; Multiple gene knockdown; n Butanol

Indexed keywords

ACETIC ACID; ALCOHOL; BUTANOL; LACTIC ACID; SUCCINIC ACID; ACETIC ACID DERIVATIVE; ESCHERICHIA COLI PROTEIN;

ADHE GENE; ARTICLE; BACTERIAL GENE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPLEX FORMATION; CONTROLLED STUDY; ESCHERICHIA COLI; FRDA GENE; GENE REPRESSION; GENE STRUCTURE; GENE TARGETING; GENETIC CODE; LDHA GENE; METABOLIC FLUX ANALYSIS; NONHUMAN; OPERON; PTA GENE; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CARBON CYCLE; CRISPR CAS SYSTEM; GENE KNOCKDOWN; GENETICS; METABOLIC ENGINEERING; METABOLISM; PROCEDURES; RNA INTERFERENCE;

ACETATES; BIOSYNTHETIC PATHWAYS; CARBON CYCLE; CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE KNOCKDOWN TECHNIQUES; LACTIC ACID; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; METABOLIC NETWORKS AND PATHWAYS; RNA INTERFERENCE;

EID: 85032740297     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-017-0802-x     Document Type: Article

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