메뉴 건너뛰기




Volumn 22, Issue 4, 2017, Pages 561-573.e4

The Epstein-Barr Virus Regulome in Lymphoblastoid Cells

Author keywords

CDKN2A B; ChIA PET; EBV regulome; EBV super enhancers; Epstein Barr virus; MYC

Indexed keywords

CELL NUCLEUS ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; INTERFERON REGULATORY FACTOR 4; MYC PROTEIN; PROTEIN MCL 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EZH2; CDKN2A PROTEIN, HUMAN; CDKN2B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 2C; EBF1 PROTEIN, HUMAN; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; EPSTEIN BARR VIRUS ANTIGEN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; MATRIX PROTEIN; MCL1 PROTEIN, HUMAN; MYC PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

EID: 85032514322     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.09.001     Document Type: Article
Times cited : (86)

References (74)
  • 1
    • 84871699564 scopus 로고    scopus 로고
    • Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
    • Adelman, K., Lis, J.T., Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat. Rev. Genet. 13 (2012), 720–731.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 720-731
    • Adelman, K.1    Lis, J.T.2
  • 2
    • 0025890062 scopus 로고
    • Early events in Epstein-Barr virus infection of human B lymphocytes
    • Alfieri, C., Birkenbach, M., Kieff, E., Early events in Epstein-Barr virus infection of human B lymphocytes. Virology 181 (1991), 595–608.
    • (1991) Virology , vol.181 , pp. 595-608
    • Alfieri, C.1    Birkenbach, M.2    Kieff, E.3
  • 5
    • 84878507873 scopus 로고    scopus 로고
    • The EBV latent antigen 3C inhibits apoptosis through targeted regulation of interferon regulatory factors 4 and 8
    • Banerjee, S., Lu, J., Cai, Q., Saha, A., Jha, H.C., Dzeng, R.K., Robertson, E.S., The EBV latent antigen 3C inhibits apoptosis through targeted regulation of interferon regulatory factors 4 and 8. PLoS Pathog., 9, 2013, e1003314.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003314
    • Banerjee, S.1    Lu, J.2    Cai, Q.3    Saha, A.4    Jha, H.C.5    Dzeng, R.K.6    Robertson, E.S.7
  • 7
    • 84917725056 scopus 로고    scopus 로고
    • Easy quantitative assessment of genome editing by sequence trace decomposition
    • Brinkman, E.K., Chen, T., Amendola, M., van Steensel, B., Easy quantitative assessment of genome editing by sequence trace decomposition. Nucleic Acids Res., 42, 2014, e168.
    • (2014) Nucleic Acids Res. , vol.42 , pp. e168
    • Brinkman, E.K.1    Chen, T.2    Amendola, M.3    van Steensel, B.4
  • 8
    • 0034705110 scopus 로고    scopus 로고
    • NF-kappa B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cells
    • Cahir-McFarland, E.D., Davidson, D.M., Schauer, S.L., Duong, J., Kieff, E., NF-kappa B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 97 (2000), 6055–6060.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6055-6060
    • Cahir-McFarland, E.D.1    Davidson, D.M.2    Schauer, S.L.3    Duong, J.4    Kieff, E.5
  • 9
    • 50149091508 scopus 로고    scopus 로고
    • The Epstein-Barr virus LF2 protein inhibits viral replication
    • Calderwood, M.A., Holthaus, A.M., Johannsen, E., The Epstein-Barr virus LF2 protein inhibits viral replication. J. Virol. 82 (2008), 8509–8519.
    • (2008) J. Virol. , vol.82 , pp. 8509-8519
    • Calderwood, M.A.1    Holthaus, A.M.2    Johannsen, E.3
  • 10
    • 80455164859 scopus 로고    scopus 로고
    • Epstein-Barr virus: an important vaccine target for cancer prevention
    • Cohen, J.I., Fauci, A.S., Varmus, H., Nabel, G.J., Epstein-Barr virus: an important vaccine target for cancer prevention. Sci. Transl. Med., 3, 2011, 107fs107.
    • (2011) Sci. Transl. Med. , vol.3 , pp. 107fs107
    • Cohen, J.I.1    Fauci, A.S.2    Varmus, H.3    Nabel, G.J.4
  • 11
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • Dekker, J., Rippe, K., Dekker, M., Kleckner, N., Capturing chromosome conformation. Science 295 (2002), 1306–1311.
    • (2002) Science , vol.295 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 13
    • 79953306808 scopus 로고    scopus 로고
    • Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
    • Elgendy, M., Sheridan, C., Brumatti, G., Martin, S.J., Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival. Mol. Cell 42 (2011), 23–35.
    • (2011) Mol. Cell , vol.42 , pp. 23-35
    • Elgendy, M.1    Sheridan, C.2    Brumatti, G.3    Martin, S.J.4
  • 14
    • 49749222804 scopus 로고
    • Virus particles in cultured lymphoblasts from Burkitt's Lymphoma
    • Epstein, M.A., Achong, B.G., Barr, Y.M., Virus particles in cultured lymphoblasts from Burkitt's Lymphoma. Lancet 1 (1964), 702–703.
    • (1964) Lancet , vol.1 , pp. 702-703
    • Epstein, M.A.1    Achong, B.G.2    Barr, Y.M.3
  • 15
  • 16
    • 0023499869 scopus 로고
    • Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines
    • Finke, J., Rowe, M., Kallin, B., Ernberg, I., Rosen, A., Dillner, J., Klein, G., Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines. J. Virol. 61 (1987), 3870–3878.
    • (1987) J. Virol. , vol.61 , pp. 3870-3878
    • Finke, J.1    Rowe, M.2    Kallin, B.3    Ernberg, I.4    Rosen, A.5    Dillner, J.6    Klein, G.7
  • 17
    • 84930330653 scopus 로고    scopus 로고
    • TRAF1 coordinates polyubiquitin signaling to enhance Epstein-Barr virus LMP1-mediated growth and survival pathway activation
    • Greenfeld, H., Takasaki, K., Walsh, M.J., Ersing, I., Bernhardt, K., Ma, Y., Fu, B., Ashbaugh, C.W., Cabo, J., Mollo, S.B., et al. TRAF1 coordinates polyubiquitin signaling to enhance Epstein-Barr virus LMP1-mediated growth and survival pathway activation. PLoS Pathog., 11, 2015, e1004890.
    • (2015) PLoS Pathog. , vol.11 , pp. e1004890
    • Greenfeld, H.1    Takasaki, K.2    Walsh, M.J.3    Ersing, I.4    Bernhardt, K.5    Ma, Y.6    Fu, B.7    Ashbaugh, C.W.8    Cabo, J.9    Mollo, S.B.10
  • 18
    • 0028124316 scopus 로고
    • The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein
    • Grossman, S.R., Johannsen, E., Tong, X., Yalamanchili, R., Kieff, E., The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein. Proc. Natl. Acad. Sci. USA 91 (1994), 7568–7572.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7568-7572
    • Grossman, S.R.1    Johannsen, E.2    Tong, X.3    Yalamanchili, R.4    Kieff, E.5
  • 19
    • 0030873493 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation
    • Harada, S., Kieff, E., Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation. J. Virol. 71 (1997), 6611–6618.
    • (1997) J. Virol. , vol.71 , pp. 6611-6618
    • Harada, S.1    Kieff, E.2
  • 20
    • 84884692313 scopus 로고    scopus 로고
    • Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9
    • Harth-Hertle, M.L., Scholz, B.A., Erhard, F., Glaser, L.V., Dölken, L., Zimmer, R., Kempkes, B., Inactivation of intergenic enhancers by EBNA3A initiates and maintains polycomb signatures across a chromatin domain encoding CXCL10 and CXCL9. PLoS Pathog., 9, 2013, e1003638.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003638
    • Harth-Hertle, M.L.1    Scholz, B.A.2    Erhard, F.3    Glaser, L.V.4    Dölken, L.5    Zimmer, R.6    Kempkes, B.7
  • 21
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S., Benner, C., Spann, N., Bertolino, E., Lin, Y.C., Laslo, P., Cheng, J.X., Murre, C., Singh, H., Glass, C.K., Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38 (2010), 576–589.
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6    Cheng, J.X.7    Murre, C.8    Singh, H.9    Glass, C.K.10
  • 22
    • 0028133036 scopus 로고
    • Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa
    • Henkel, T., Ling, P.D., Hayward, S.D., Peterson, M.G., Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa. Science 265 (1994), 92–95.
    • (1994) Science , vol.265 , pp. 92-95
    • Henkel, T.1    Ling, P.D.2    Hayward, S.D.3    Peterson, M.G.4
  • 23
    • 0037033108 scopus 로고    scopus 로고
    • Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP)
    • Hickabottom, M., Parker, G.A., Freemont, P., Crook, T., Allday, M.J., Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP). J. Biol. Chem. 277 (2002), 47197–47204.
    • (2002) J. Biol. Chem. , vol.277 , pp. 47197-47204
    • Hickabottom, M.1    Parker, G.A.2    Freemont, P.3    Crook, T.4    Allday, M.J.5
  • 24
    • 85021308890 scopus 로고    scopus 로고
    • Gordon Wilson lecture: infectious disease causes of cancer: opportunities for prevention and treatment
    • Howley, P.M., Gordon Wilson lecture: infectious disease causes of cancer: opportunities for prevention and treatment. Trans. Am. Clin. Climatol. Assoc. 126 (2015), 117–132.
    • (2015) Trans. Am. Clin. Climatol. Assoc. , vol.126 , pp. 117-132
    • Howley, P.M.1
  • 28
    • 0032923696 scopus 로고    scopus 로고
    • The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2
    • Kaiser, C., Laux, G., Eick, D., Jochner, N., Bornkamm, G.W., Kempkes, B., The proto-oncogene c-myc is a direct target gene of Epstein-Barr virus nuclear antigen 2. J. Virol. 73 (1999), 4481–4484.
    • (1999) J. Virol. , vol.73 , pp. 4481-4484
    • Kaiser, C.1    Laux, G.2    Eick, D.3    Jochner, N.4    Bornkamm, G.W.5    Kempkes, B.6
  • 29
    • 84956815097 scopus 로고    scopus 로고
    • EBNA3C directs recruitment of RBPJ (CBF1) to chromatin during the process of gene repression in EBV infected B cells
    • Kalchschmidt, J.S., Gillman, A.C., Paschos, K., Bazot, Q., Kempkes, B., Allday, M.J., EBNA3C directs recruitment of RBPJ (CBF1) to chromatin during the process of gene repression in EBV infected B cells. PLoS Pathog., 12, 2016, e1005383.
    • (2016) PLoS Pathog. , vol.12 , pp. e1005383
    • Kalchschmidt, J.S.1    Gillman, A.C.2    Paschos, K.3    Bazot, Q.4    Kempkes, B.5    Allday, M.J.6
  • 32
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead, B., Trapnell, C., Pop, M., Salzberg, S.L., Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol., 10, 2009, R25.
    • (2009) Genome Biol. , vol.10 , pp. R25
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 34
    • 85002694679 scopus 로고    scopus 로고
    • Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation
    • Liang, J., Zhou, H., Gerdt, C., Tan, M., Colson, T., Kaye, K.M., Kieff, E., Zhao, B., Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation. Proc. Natl. Acad. Sci. USA 113 (2016), 14121–14126.
    • (2016) Proc. Natl. Acad. Sci. USA , vol.113 , pp. 14121-14126
    • Liang, J.1    Zhou, H.2    Gerdt, C.3    Tan, M.4    Colson, T.5    Kaye, K.M.6    Kieff, E.7    Zhao, B.8
  • 36
    • 0027358873 scopus 로고
    • The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer-binding protein
    • Ling, P.D., Rawlins, D.R., Hayward, S.D., The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer-binding protein. Proc. Natl. Acad. Sci. USA 90 (1993), 9237–9241.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9237-9241
    • Ling, P.D.1    Rawlins, D.R.2    Hayward, S.D.3
  • 38
    • 84901773703 scopus 로고    scopus 로고
    • Epstein-Barr Virus, Vol. 2
    • Eighth Edition Lippincott Williams & Wilkins, a Wolters Kluwer Business
    • Longnecker, R., Kieff, E., Cohen, J.I., Epstein-Barr Virus, Vol. 2. Eighth Edition, 2013, Lippincott Williams & Wilkins, a Wolters Kluwer Business.
    • (2013)
    • Longnecker, R.1    Kieff, E.2    Cohen, J.I.3
  • 41
    • 0141856301 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth
    • Maruo, S., Johannsen, E., Illanes, D., Cooper, A., Kieff, E., Epstein-Barr virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth. J. Virol. 77 (2003), 10437–10447.
    • (2003) J. Virol. , vol.77 , pp. 10437-10447
    • Maruo, S.1    Johannsen, E.2    Illanes, D.3    Cooper, A.4    Kieff, E.5
  • 42
    • 23244460780 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical
    • Maruo, S., Johannsen, E., Illanes, D., Cooper, A., Zhao, B., Kieff, E., Epstein-Barr virus nuclear protein 3A domains essential for growth of lymphoblasts: transcriptional regulation through RBP-Jkappa/CBF1 is critical. J. Virol. 79 (2005), 10171–10179.
    • (2005) J. Virol. , vol.79 , pp. 10171-10179
    • Maruo, S.1    Johannsen, E.2    Illanes, D.3    Cooper, A.4    Zhao, B.5    Kieff, E.6
  • 43
    • 33845900225 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells
    • Maruo, S., Wu, Y., Ishikawa, S., Kanda, T., Iwakiri, D., Takada, K., Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 103 (2006), 19500–19505.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 19500-19505
    • Maruo, S.1    Wu, Y.2    Ishikawa, S.3    Kanda, T.4    Iwakiri, D.5    Takada, K.6
  • 44
    • 63149180521 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth
    • Maruo, S., Wu, Y., Ito, T., Kanda, T., Kieff, E.D., Takada, K., Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth. Proc. Natl. Acad. Sci. USA 106 (2009), 4419–4424.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4419-4424
    • Maruo, S.1    Wu, Y.2    Ito, T.3    Kanda, T.4    Kieff, E.D.5    Takada, K.6
  • 45
    • 79952170344 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
    • Maruo, S., Zhao, B., Johannsen, E., Kieff, E., Zou, J., Takada, K., Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression. Proc. Natl. Acad. Sci. USA 108 (2011), 1919–1924.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 1919-1924
    • Maruo, S.1    Zhao, B.2    Johannsen, E.3    Kieff, E.4    Zou, J.5    Takada, K.6
  • 47
    • 84955619179 scopus 로고    scopus 로고
    • The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth
    • Ohashi, M., Holthaus, A.M., Calderwood, M.A., Lai, C.Y., Krastins, B., Sarracino, D., Johannsen, E., The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog., 11, 2015, e1004822.
    • (2015) PLoS Pathog. , vol.11 , pp. e1004822
    • Ohashi, M.1    Holthaus, A.M.2    Calderwood, M.A.3    Lai, C.Y.4    Krastins, B.5    Sarracino, D.6    Johannsen, E.7
  • 48
    • 79952901680 scopus 로고    scopus 로고
    • Enhancer function: new insights into the regulation of tissue-specific gene expression
    • Ong, C.T., Corces, V.G., Enhancer function: new insights into the regulation of tissue-specific gene expression. Nat. Rev. Genet. 12 (2011), 283–293.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 283-293
    • Ong, C.T.1    Corces, V.G.2
  • 49
    • 84867288340 scopus 로고    scopus 로고
    • BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV
    • Paschos, K., Parker, G.A., Watanatanasup, E., White, R.E., Allday, M.J., BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV. Nucleic Acids Res. 40 (2012), 7233–7246.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 7233-7246
    • Paschos, K.1    Parker, G.A.2    Watanatanasup, E.3    White, R.E.4    Allday, M.J.5
  • 53
    • 79956348321 scopus 로고    scopus 로고
    • EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding
    • Portal, D., Zhao, B., Calderwood, M.A., Sommermann, T., Johannsen, E., Kieff, E., EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding. Proc. Natl. Acad. Sci. USA 108 (2011), 7808–7813.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 7808-7813
    • Portal, D.1    Zhao, B.2    Calderwood, M.A.3    Sommermann, T.4    Johannsen, E.5    Kieff, E.6
  • 55
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • Quinlan, A.R., Hall, I.M., BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26 (2010), 841–842.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 56
    • 0029990265 scopus 로고    scopus 로고
    • The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa)
    • Robertson, E.S., Lin, J., Kieff, E., The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa). J. Virol. 70 (1996), 3068–3074.
    • (1996) J. Virol. , vol.70 , pp. 3068-3074
    • Robertson, E.S.1    Lin, J.2    Kieff, E.3
  • 57
    • 8744233976 scopus 로고    scopus 로고
    • Epstein-Barr virus quantitation by real-time PCR targeting multiple gene segments: a novel approach to screen for the virus in paraffin-embedded tissue and plasma
    • Ryan, J.L., Fan, H., Glaser, S.L., Schichman, S.A., Raab-Traub, N., Gulley, M.L., Epstein-Barr virus quantitation by real-time PCR targeting multiple gene segments: a novel approach to screen for the virus in paraffin-embedded tissue and plasma. J. Mol. Diagn. 6 (2004), 378–385.
    • (2004) J. Mol. Diagn. , vol.6 , pp. 378-385
    • Ryan, J.L.1    Fan, H.2    Glaser, S.L.3    Schichman, S.A.4    Raab-Traub, N.5    Gulley, M.L.6
  • 60
    • 84899493057 scopus 로고    scopus 로고
    • ngs.plot: quick mining and visualization of next-generation sequencing data by integrating genomic databases
    • Shen, L., Shao, N., Liu, X., Nestler, E., ngs.plot: quick mining and visualization of next-generation sequencing data by integrating genomic databases. BMC Genomics, 15, 2014, 284.
    • (2014) BMC Genomics , vol.15 , pp. 284
    • Shen, L.1    Shao, N.2    Liu, X.3    Nestler, E.4
  • 61
    • 84962440911 scopus 로고    scopus 로고
    • Targeting CDK4 and CDK6: from discovery to therapy
    • Sherr, C.J., Beach, D., Shapiro, G.I., Targeting CDK4 and CDK6: from discovery to therapy. Cancer Discov. 6 (2016), 353–367.
    • (2016) Cancer Discov. , vol.6 , pp. 353-367
    • Sherr, C.J.1    Beach, D.2    Shapiro, G.I.3
  • 62
    • 0028233417 scopus 로고
    • EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus
    • Sinclair, A.J., Palmero, I., Peters, G., Farrell, P.J., EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO J. 13 (1994), 3321–3328.
    • (1994) EMBO J. , vol.13 , pp. 3321-3328
    • Sinclair, A.J.1    Palmero, I.2    Peters, G.3    Farrell, P.J.4
  • 63
    • 77954664053 scopus 로고    scopus 로고
    • Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP
    • Skalska, L., White, R.E., Franz, M., Ruhmann, M., Allday, M.J., Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP. PLoS Pathog., 6, 2010, e1000951.
    • (2010) PLoS Pathog. , vol.6 , pp. e1000951
    • Skalska, L.1    White, R.E.2    Franz, M.3    Ruhmann, M.4    Allday, M.J.5
  • 64
    • 84874772161 scopus 로고    scopus 로고
    • Induction of p16(INK4A) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines
    • Skalska, L., White, R.E., Parker, G.A., Sinclair, A.J., Paschos, K., Allday, M.J., Induction of p16(INK4A) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines. PLoS Pathog., 9, 2013, e1003187.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003187
    • Skalska, L.1    White, R.E.2    Parker, G.A.3    Sinclair, A.J.4    Paschos, K.5    Allday, M.J.6
  • 66
    • 84961164811 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 3 (EBNA3) proteins regulate EBNA2 binding to distinct RBPJ genomic sites
    • Wang, A., Welch, R., Zhao, B., Ta, T., Keles, S., Johannsen, E., Epstein-Barr virus nuclear antigen 3 (EBNA3) proteins regulate EBNA2 binding to distinct RBPJ genomic sites. J. Virol. 90 (2015), 2906–2919.
    • (2015) J. Virol. , vol.90 , pp. 2906-2919
    • Wang, A.1    Welch, R.2    Zhao, B.3    Ta, T.4    Keles, S.5    Johannsen, E.6
  • 67
    • 0029795731 scopus 로고    scopus 로고
    • Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines
    • Wang, S., Rowe, M., Lundgren, E., Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines. Cancer Res. 56 (1996), 4610–4613.
    • (1996) Cancer Res. , vol.56 , pp. 4610-4613
    • Wang, S.1    Rowe, M.2    Lundgren, E.3
  • 68
    • 84876216563 scopus 로고    scopus 로고
    • Master transcription factors and mediator establish super-enhancers at key cell identity genes
    • Whyte, Warren A., Orlando, David A., Hnisz, D., Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong I., Young, Richard A., Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell 153 (2013), 307–319.
    • (2013) Cell , vol.153 , pp. 307-319
    • Whyte, W.A.1    Orlando, D.A.2    Hnisz, D.3    Abraham, B.J.4    Lin, C.Y.5    Kagey, M.H.6    Rahl, P.B.7    Lee, T.I.8    Young, R.A.9
  • 69
    • 84985914211 scopus 로고    scopus 로고
    • MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs
    • Wood, C.D., Veenstra, H., Khasnis, S., Gunnell, A., Webb, H.M., Shannon-Lowe, C., Andrews, S., Osborne, C.S., West, M.J., MYC activation and BCL2L11 silencing by a tumour virus through the large-scale reconfiguration of enhancer-promoter hubs. Elife, 5, 2016, e18270.
    • (2016) Elife , vol.5 , pp. e18270
    • Wood, C.D.1    Veenstra, H.2    Khasnis, S.3    Gunnell, A.4    Webb, H.M.5    Shannon-Lowe, C.6    Andrews, S.7    Osborne, C.S.8    West, M.J.9
  • 73
    • 84878658527 scopus 로고    scopus 로고
    • IntPath – an integrated pathway gene relationship database for model organisms and important pathogens
    • Zhou, H., Jin, J., Zhang, H., Yi, B., Wozniak, M., Wong, L., IntPath – an integrated pathway gene relationship database for model organisms and important pathogens. BMC Syst. Biol., 6(Suppl 2), 2012, S2.
    • (2012) BMC Syst. Biol. , vol.6 , pp. S2
    • Zhou, H.1    Jin, J.2    Zhang, H.3    Yi, B.4    Wozniak, M.5    Wong, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.