Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 49, 2016, Pages 14121-14126

  Liang, Jun ^a,b   Zhou, Hufeng ^a,b   Gerdt, Catherine ^a   Tan, Min ^a   Colson, Tyler ^a   Kaye, Kenneth M ^a   Kieff, Elliott ^a,b   Zhao, Bo ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Epstein Barr virus; ERNA; MYC; Super enhancer

Indexed keywords

BROMODOMAIN CONTAINING PROTEIN 4; EPSTEIN BARR VIRUS ANTIGEN 2; MYC PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; BRD4 PROTEIN, HUMAN; MYC PROTEIN, HUMAN; NUCLEAR PROTEIN; SND1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENHANCER REGION; EPSTEIN BARR VIRUS; GENE SILENCING; LYMPHOBLAST; LYMPHOBLASTOID CELL LINE; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; TRANSCRIPTION INITIATION SITE; CELL LINE; HOST PATHOGEN INTERACTION; HUMAN; LYMPHOPROLIFERATIVE DISEASE; METABOLISM; PHYSIOLOGY; VIROLOGY;

CELL LINE; ENHANCER ELEMENTS, GENETIC; HERPESVIRUS 4, HUMAN; HOST-PATHOGEN INTERACTIONS; HUMANS; LYMPHOPROLIFERATIVE DISORDERS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; TRANSCRIPTION FACTORS;

EID: 85002694679     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1616697113     Document Type: Article

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