TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Greenfeld, Hannah ^a   Takasaki, Kaoru ^a   Walsh, Michael J ^a   Ersing, Ina ^a   Bernhardt, Katharina ^a   Ma, Yijie ^a   Fu, Bishi ^b   Ashbaugh, Camille W ^a   Cabo, Jackson ^a   Mollo, Sarah B ^a   Zhou, Hufeng ^a   Li, Shitao ^b,c   Gewurz, Benjamin E ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LATENT MEMBRANE PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; POLYUBIQUITIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; EBV-ASSOCIATED MEMBRANE ANTIGEN, EPSTEIN-BARR VIRUS; HYBRID PROTEIN; LYSINE; MATRIX PROTEIN; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; CONFOCAL MICROSCOPY; EPSTEIN BARR VIRUS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; LYMPHOBLASTOID CELL LINE; MASS SPECTROMETRY; MUTAGENESIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; B LYMPHOCYTE; CHEMISTRY; EPSTEIN BARR VIRUS INFECTION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; MUTATION; PROTEIN DOMAIN; RNA INTERFERENCE; TUMOR CELL LINE; VIROLOGY; VIRUS CELL TRANSFORMATION;

HUMAN HERPESVIRUS 4;

B-LYMPHOCYTES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, VIRAL; EPSTEIN-BARR VIRUS INFECTIONS; HEK293 CELLS; HERPESVIRUS 4, HUMAN; HUMANS; LYSINE; MUTATION; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 1; TNF RECEPTOR-ASSOCIATED FACTOR 2; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITINATION; VIRAL MATRIX PROTEINS;

EID: 84930330653     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004890     Document Type: Article

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