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Volumn 17, Issue 11, 2017, Pages 691-702

Heterogeneity in tuberculosis

Author keywords

[No Author keywords available]

Indexed keywords

FLUORINE 18; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; TUBERCULOSTATIC AGENT; TUMOR NECROSIS FACTOR;

EID: 85032363179     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri.2017.69     Document Type: Review
Times cited : (350)

References (135)
  • 2
    • 0012746992 scopus 로고    scopus 로고
    • The growing burden of tuberculosis: Global trends and interactions with the HIV epidemic
    • Corbett, E. L. et al. The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch. Intern. Med. 163, 1009-1021 (2003).
    • (2003) Arch. Intern. Med , vol.163 , pp. 1009-1021
    • Corbett, E.L.1
  • 3
    • 79959927732 scopus 로고    scopus 로고
    • Tuberculosis
    • Lawn, S. D. & Zumla, A. I. Tuberculosis. Lancet 378, 57-72 (2011).
    • (2011) Lancet , vol.378 , pp. 57-72
    • Lawn, S.D.1    Zumla, A.I.2
  • 4
    • 84935892144 scopus 로고    scopus 로고
    • World Health Organization World Health Organization
    • World Health Organization. Global Tuberculosis Report 2015 (World Health Organization, 2015).
    • (2015) Global Tuberculosis Report 2015
  • 5
    • 84857571954 scopus 로고    scopus 로고
    • Risk of progression to active tuberculosis following reinfection with Mycobacterium tuberculosis
    • Andrews, J. R. et al. Risk of progression to active tuberculosis following reinfection with Mycobacterium tuberculosis. Clin. Infect. Dis. 54, 784-791 (2012).
    • (2012) Clin. Infect. Dis , vol.54 , pp. 784-791
    • Andrews, J.R.1
  • 6
    • 77956216718 scopus 로고    scopus 로고
    • Understanding latent tuberculosis: A moving target
    • Lin, P. L. & Flynn, J. L. Understanding latent tuberculosis: a moving target. J. Immunol. 185, 15-22 (2010).
    • (2010) J. Immunol , vol.185 , pp. 15-22
    • Lin, P.L.1    Flynn, J.L.2
  • 7
    • 84915746502 scopus 로고    scopus 로고
    • PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis
    • Chen, R. Y. et al. PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis. Sci. Transl Med. 6, 265ra166 (2014).
    • (2014) Sci. Transl Med , vol.6 , pp. 265ra166
    • Chen, R.Y.1
  • 9
    • 2642623535 scopus 로고
    • Some clinical features of tuberculosis
    • Poulsen, A. Some clinical features of tuberculosis. Acta Tuberc. Scand. 33, 37-92 (1957).
    • (1957) Acta Tuberc. Scand , vol.33 , pp. 37-92
    • Poulsen, A.1
  • 10
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
    • Barry, C. E. 3rd et al. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat. Rev. Microbiol. 7, 845-855 (2009).
    • (2009) Nat. Rev. Microbiol , vol.7 , pp. 845-855
    • Barry, C.E.1
  • 12
    • 84987660570 scopus 로고    scopus 로고
    • 18F]fluoro-D-glucose positron emission and computed tomography
    • 18F]fluoro-D-glucose positron emission and computed tomography. Nat. Med. 22, 1090-1093 (2016).
    • (2016) Nat. Med , vol.22 , pp. 1090-1093
    • Esmail, H.1
  • 13
    • 0141669013 scopus 로고    scopus 로고
    • Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. Tuberculosis infection
    • Capuano, S. V. et al. Experimental Mycobacterium tuberculosis infection of cynomolgus macaques closely resembles the various manifestations of human M. tuberculosis infection. Infect. Immun. 71, 5831-5844 (2003).
    • (2003) Infect. Immun , vol.71 , pp. 5831-5844
    • Capuano, S.V.1
  • 14
    • 70349427123 scopus 로고    scopus 로고
    • Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
    • Lin, P. L. et al. Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model. Infect. Immun. 77, 4631-4642 (2009).
    • (2009) Infect. Immun , vol.77 , pp. 4631-4642
    • Lin, P.L.1
  • 15
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry, M. P. et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466, 973-977 (2010).
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1
  • 16
    • 80055042377 scopus 로고    scopus 로고
    • Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis
    • Maertzdorf, J. et al. Functional correlations of pathogenesis-driven gene expression signatures in tuberculosis. PLoS ONE 6, e26938 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e26938
    • Maertzdorf, J.1
  • 17
    • 84866686896 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis
    • Ottenhoff, T. H. et al. Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS ONE 7, e45839 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e45839
    • Ottenhoff, T.H.1
  • 18
    • 84923164028 scopus 로고    scopus 로고
    • The human immune response to tuberculosis and its treatment: A view from the blood
    • Cliff, J. M., Kaufmann, S. H., McShane, H., van Helden, P. & O'Garra, A. The human immune response to tuberculosis and its treatment: a view from the blood. Immunol. Rev. 264, 88-102 (2015).
    • (2015) Immunol. Rev , vol.264 , pp. 88-102
    • Cliff, J.M.1    Kaufmann, S.H.2    McShane, H.3    Van Helden, P.4    O'Garra, A.5
  • 19
    • 84867031010 scopus 로고    scopus 로고
    • Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy
    • Bloom, C. I. et al. Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy. PLoS ONE 7, e46191 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e46191
    • Bloom, C.I.1
  • 20
    • 84872978097 scopus 로고    scopus 로고
    • Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response
    • Cliff, J. M. et al. Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. J. Infect. Dis. 207, 18-29 (2013).
    • (2013) J. Infect. Dis , vol.207 , pp. 18-29
    • Cliff, J.M.1
  • 21
    • 84877267006 scopus 로고    scopus 로고
    • Advances in the development of new tuberculosis drugs and treatment regimens
    • Zumla, A., Nahid, P. & Cole, S. T. Advances in the development of new tuberculosis drugs and treatment regimens. Nat. Rev. Drug Discov. 12, 388-404 (2013).
    • (2013) Nat. Rev. Drug Discov , vol.12 , pp. 388-404
    • Zumla, A.1    Nahid, P.2    Cole, S.T.3
  • 22
    • 79251589638 scopus 로고    scopus 로고
    • The challenge of new drug discovery for tuberculosis
    • Koul, A., Arnoult, E., Lounis, N., Guillemont, J. & Andries, K. The challenge of new drug discovery for tuberculosis. Nature 469, 483-490 (2011).
    • (2011) Nature , vol.469 , pp. 483-490
    • Koul, A.1    Arnoult, E.2    Lounis, N.3    Guillemont, J.4    Andries, K.5
  • 23
    • 84991227395 scopus 로고    scopus 로고
    • The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis
    • Blankley, S. et al. The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis. PLoS ONE 11, e0162220 (2016).
    • (2016) PLoS ONE , vol.11 , pp. e0162220
    • Blankley, S.1
  • 24
    • 84859371920 scopus 로고    scopus 로고
    • Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections
    • Banchereau, R. et al. Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections. PLoS ONE 7, e34390 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e34390
    • Banchereau, R.1
  • 25
    • 84975914135 scopus 로고    scopus 로고
    • A blood RNA signature for tuberculosis disease risk: A prospective cohort study
    • Zak, D. E. et al. A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Lancet 387, 2312-2322 (2016).
    • (2016) Lancet , vol.387 , pp. 2312-2322
    • Zak, D.E.1
  • 26
    • 77958003946 scopus 로고    scopus 로고
    • Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas
    • Mehra, S. et al. Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas. PLoS ONE 5, e12266 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e12266
    • Mehra, S.1
  • 27
    • 85001976231 scopus 로고    scopus 로고
    • Early whole blood transcriptional signatures are associated with severity of lung inflammation in cynomolgus macaques with Mycobacterium tuberculosis infection
    • Gideon, H. P., Skinner, J. A., Baldwin, N., Flynn, J. L. & Lin, P. L. Early whole blood transcriptional signatures are associated with severity of lung inflammation in cynomolgus macaques with Mycobacterium tuberculosis infection. J. Immunol. 197, 4817-4828 (2016).
    • (2016) J. Immunol , vol.197 , pp. 4817-4828
    • Gideon, H.P.1    Skinner, J.A.2    Baldwin, N.3    Flynn, J.L.4    Lin, P.L.5
  • 28
    • 0020526146 scopus 로고
    • Granulomatous inflammation - A review
    • Williams, G. T. & Williams, W. J. Granulomatous inflammation - a review. J. Clin. Pathol. 36, 723-733 (1983).
    • (1983) J. Clin. Pathol , vol.36 , pp. 723-733
    • Williams, G.T.1    Williams, W.J.2
  • 29
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell, D. G., Cardona, P. J., Kim, M. J., Allain, S. & Altare, F. Foamy macrophages and the progression of the human tuberculosis granuloma. Nat. Immunol. 10, 943-948 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.J.2    Kim, M.J.3    Allain, S.4    Altare, F.5
  • 30
    • 79955111092 scopus 로고    scopus 로고
    • Macrophages and control of granulomatous inflammation in tuberculosis
    • Flynn, J. L., Chan, J. & Lin, P. L. Macrophages and control of granulomatous inflammation in tuberculosis. Mucosal Immunol. 4, 271-278 (2011).
    • (2011) Mucosal Immunol , vol.4 , pp. 271-278
    • Flynn, J.L.1    Chan, J.2    Lin, P.L.3
  • 31
    • 58149083837 scopus 로고    scopus 로고
    • The role of the granuloma in expansion and dissemination of early tuberculous infection
    • Davis, J. M. & Ramakrishnan, L. The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell 136, 37-49 (2009).
    • (2009) Cell , vol.136 , pp. 37-49
    • Davis, J.M.1    Ramakrishnan, L.2
  • 32
    • 84860247190 scopus 로고    scopus 로고
    • Revisiting the role of the granuloma in tuberculosis
    • Ramakrishnan, L. Revisiting the role of the granuloma in tuberculosis. Nat. Rev. Immunol. 12, 352-366 (2012).
    • (2012) Nat. Rev. Immunol , vol.12 , pp. 352-366
    • Ramakrishnan, L.1
  • 33
    • 4444277765 scopus 로고    scopus 로고
    • Mutual attraction: Does it benefit the host or the bug?
    • Flynn, J. L. Mutual attraction: does it benefit the host or the bug? Nat. Immunol. 5, 778-779 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 778-779
    • Flynn, J.L.1
  • 34
    • 84875498895 scopus 로고    scopus 로고
    • The immune response in tuberculosis
    • O'Garra, A. et al. The immune response in tuberculosis. Annu. Rev. Immunol. 31, 475-527 (2013).
    • (2013) Annu. Rev. Immunol , vol.31 , pp. 475-527
    • O'Garra, A.1
  • 36
    • 79955460244 scopus 로고    scopus 로고
    • Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection
    • Ford, C. B. et al. Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection. Nat. Genet. 43, 482-486 (2011).
    • (2011) Nat. Genet , vol.43 , pp. 482-486
    • Ford, C.B.1
  • 37
    • 84891853921 scopus 로고    scopus 로고
    • Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
    • Lin, P. L. et al. Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing. Nat. Med. 20, 75-79 (2014).
    • (2014) Nat. Med , vol.20 , pp. 75-79
    • Lin, P.L.1
  • 38
    • 84940055246 scopus 로고    scopus 로고
    • Lesion-specific immune response in granulomas of patients with pulmonary tuberculosis: A pilot study
    • Subbian, S. et al. Lesion-specific immune response in granulomas of patients with pulmonary tuberculosis: a pilot study. PLoS ONE 10, e0132249 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0132249
    • Subbian, S.1
  • 39
    • 84923172431 scopus 로고    scopus 로고
    • Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses
    • Lenaerts, A., Barry, C. E. III & Dartois, V. Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses. Immunol. Rev. 264, 288-307 (2015).
    • (2015) Immunol. Rev , vol.264 , pp. 288-307
    • Lenaerts, A.1    Barry, C.E.2    Dartois, V.3
  • 40
    • 84900426355 scopus 로고    scopus 로고
    • 18fluorodeoxyglucose positron emission tomography coregistered with computed tomography predict outcome after Mycobacterium tuberculosis infection in cynomolgus macaques
    • 18fluorodeoxyglucose positron emission tomography coregistered with computed tomography predict outcome after Mycobacterium tuberculosis infection in cynomolgus macaques. Infect. Immun. 82, 2400-2404 (2014).
    • (2014) Infect. Immun , vol.82 , pp. 2400-2404
    • Coleman, M.T.1
  • 41
    • 84965125893 scopus 로고    scopus 로고
    • The importance of first impressions: Early events in Mycobacterium tuberculosis infection influence outcome
    • Cadena, A. M., Flynn, J. L. & Fortune, S. M. The importance of first impressions: early events in Mycobacterium tuberculosis infection influence outcome. mBio 7, e00342-16 (2016).
    • (2016) MBio , vol.7 , pp. e00342-e00416
    • Cadena, A.M.1    Flynn, J.L.2    Fortune, S.M.3
  • 42
    • 84992756754 scopus 로고    scopus 로고
    • Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis
    • Lieberman, T. D. et al. Genomic diversity in autopsy samples reveals within-host dissemination of HIV-associated Mycobacterium tuberculosis. Nat. Med. 22, 1470-1474 (2016).
    • (2016) Nat. Med , vol.22 , pp. 1470-1474
    • Lieberman, T.D.1
  • 43
    • 79955110091 scopus 로고    scopus 로고
    • Role of innate cytokines in mycobacterial infection
    • Cooper, A. M., Mayer-Barber, K. D. & Sher, A. Role of innate cytokines in mycobacterial infection. Mucosal Immunol. 4, 252-260 (2011).
    • (2011) Mucosal Immunol , vol.4 , pp. 252-260
    • Cooper, A.M.1    Mayer-Barber, K.D.2    Sher, A.3
  • 44
    • 84940439333 scopus 로고    scopus 로고
    • The innate immune response in human tuberculosis
    • Lerner, T. R., Borel, S. & Gutierrez, M. G. The innate immune response in human tuberculosis. Cell. Microbiol. 17, 1277-1285 (2015).
    • (2015) Cell. Microbiol , vol.17 , pp. 1277-1285
    • Lerner, T.R.1    Borel, S.2    Gutierrez, M.G.3
  • 45
    • 33745622432 scopus 로고    scopus 로고
    • Early events in Mycobacterium tuberculosis infection in cynomolgus macaques
    • Lin, P. L. et al. Early events in Mycobacterium tuberculosis infection in cynomolgus macaques. Infect. Immun. 74, 3790-3803 (2006).
    • (2006) Infect. Immun , vol.74 , pp. 3790-3803
    • Lin, P.L.1
  • 46
    • 84962054174 scopus 로고    scopus 로고
    • Inflammatory signaling in human tuberculosis granulomas is spatially organized
    • Marakalala, M. J. et al. Inflammatory signaling in human tuberculosis granulomas is spatially organized. Nat. Med. 22, 531-538 (2016).
    • (2016) Nat. Med , vol.22 , pp. 531-538
    • Marakalala, M.J.1
  • 47
    • 79953194081 scopus 로고    scopus 로고
    • Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation
    • Fallahi-Sichani, M., El-Kebir, M., Marino, S., Kirschner, D. E. & Linderman, J. J. Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation. J. Immunol. 186, 3472-3483 (2011).
    • (2011) J. Immunol , vol.186 , pp. 3472-3483
    • Fallahi-Sichani, M.1    El-Kebir, M.2    Marino, S.3    Kirschner, D.E.4    Linderman, J.J.5
  • 48
    • 84883668448 scopus 로고    scopus 로고
    • Modeling the Mycobacterium tuberculosis granuloma - The critical battlefield in host immunity and disease
    • Guirado, E. & Schlesinger, L. S. Modeling the Mycobacterium tuberculosis granuloma - the critical battlefield in host immunity and disease. Front. Immunol. 4, 98 (2013).
    • (2013) Front. Immunol , vol.4 , pp. 98
    • Guirado, E.1    Schlesinger, L.S.2
  • 49
    • 10744233688 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis growth at the cavity surface: A microenvironment with failed immunity
    • Kaplan, G. et al. Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity. Infect. Immun. 71, 7099-7108 (2003).
    • (2003) Infect. Immun , vol.71 , pp. 7099-7108
    • Kaplan, G.1
  • 50
    • 84864357703 scopus 로고    scopus 로고
    • The immunological life cycle of tuberculosis
    • Ernst, J. D. The immunological life cycle of tuberculosis. Nat. Rev. Immunol. 12, 581-591 (2012).
    • (2012) Nat. Rev. Immunol , vol.12 , pp. 581-591
    • Ernst, J.D.1
  • 51
    • 84982958042 scopus 로고    scopus 로고
    • PET CT identifies reactivation risk in cynomolgus macaques with latent M
    • Lin, P. L. et al. PET CT identifies reactivation risk in cynomolgus macaques with latent M. tuberculosis. PLoS Pathog. 12, e1005739 (2016).
    • (2016) Tuberculosis. PLoS Pathog , vol.12 , pp. e1005739
    • Lin, P.L.1
  • 52
    • 84987660805 scopus 로고    scopus 로고
    • Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
    • Malherbe, S. T. et al. Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nat. Med. 22, 1094-1100 (2016).
    • (2016) Nat. Med , vol.22 , pp. 1094-1100
    • Malherbe, S.T.1
  • 53
    • 84880126124 scopus 로고    scopus 로고
    • Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
    • Mattila, J. T. et al. Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms. J. Immunol. 191, 773-784 (2013).
    • (2013) J. Immunol , vol.191 , pp. 773-784
    • Mattila, J.T.1
  • 54
    • 84856693171 scopus 로고    scopus 로고
    • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
    • Tobin, D. M. et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 148, 434-446 (2012).
    • (2012) Cell , vol.148 , pp. 434-446
    • Tobin, D.M.1
  • 55
    • 58149296186 scopus 로고    scopus 로고
    • 4 in the induction of macrophage death
    • 4 in the induction of macrophage death. J. Exp. Med. 205, 2791-2801 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 2791-2801
    • Chen, M.1
  • 56
    • 67651171188 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair
    • Divangahi, M. et al. Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nat. Immunol. 10, 899-906 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 899-906
    • Divangahi, M.1
  • 57
    • 77954957267 scopus 로고    scopus 로고
    • Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis
    • Divangahi, M., Desjardins, D., Nunes-Alves, C., Remold, H. G. & Behar, S. M. Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis. Nat. Immunol. 11, 751-758 (2010).
    • (2010) Nat. Immunol , vol.11 , pp. 751-758
    • Divangahi, M.1    Desjardins, D.2    Nunes-Alves, C.3    Remold, H.G.4    Behar, S.M.5
  • 58
    • 84879533832 scopus 로고    scopus 로고
    • Dying to live: How the death modality of the infected macrophage affects immunity to tuberculosis
    • Divangahi, M., Behar, S. M. & Remold, H. Dying to live: how the death modality of the infected macrophage affects immunity to tuberculosis. Adv. Exp. Med. Biol. 783, 103-120 (2013).
    • (2013) Adv. Exp. Med. Biol , vol.783 , pp. 103-120
    • Divangahi, M.1    Behar, S.M.2    Remold, H.3
  • 59
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type i interferon crosstalk
    • Mayer-Barber, K. D. et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature 5 11, 99-103 (2014).
    • (2014) Nature , vol.5 , Issue.11 , pp. 99-103
    • Mayer-Barber, K.D.1
  • 60
    • 84925703181 scopus 로고    scopus 로고
    • Advancing host-directed therapy for tuberculosis
    • Wallis, R. S. & Hafner, R. Advancing host-directed therapy for tuberculosis. Nat. Rev. Immunol. 15, 255-263 (2015).
    • (2015) Nat. Rev. Immunol , vol.15 , pp. 255-263
    • Wallis, R.S.1    Hafner, R.2
  • 61
    • 84924281504 scopus 로고    scopus 로고
    • The balance between protective and pathogenic immune responses in the TB-infected lung
    • Orme, I. M., Robinson, R. T. & Cooper, A. M. The balance between protective and pathogenic immune responses in the TB-infected lung. Nat. Immunol. 16, 57-63 (2015).
    • (2015) Nat. Immunol , vol.16 , pp. 57-63
    • Orme, I.M.1    Robinson, R.T.2    Cooper, A.M.3
  • 62
    • 84923842431 scopus 로고    scopus 로고
    • Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization
    • Gideon, H. P. et al. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLoS Pathog. 11, e1004603 (2015).
    • (2015) PLoS Pathog , vol.11 , pp. e1004603
    • Gideon, H.P.1
  • 63
    • 84880273351 scopus 로고    scopus 로고
    • Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection
    • Cilfone, N. A., Perry, C. R., Kirschner, D. E. & Linderman, J. J. Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection. PLoS ONE 8, e68680 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e68680
    • Cilfone, N.A.1    Perry, C.R.2    Kirschner, D.E.3    Linderman, J.J.4
  • 64
    • 84920459654 scopus 로고    scopus 로고
    • Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during Mycobacterium tuberculosis infection
    • Cilfone, N. A. et al. Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during Mycobacterium tuberculosis infection. J. Immunol. 194, 664-677 (2015).
    • (2015) J. Immunol , vol.194 , pp. 664-677
    • Cilfone, N.A.1
  • 65
    • 84911207256 scopus 로고    scopus 로고
    • Beyond macrophages: The diversity of mononuclear cells in tuberculosis
    • Srivastava, S., Ernst, J. D. & Desvignes, L. Beyond macrophages: the diversity of mononuclear cells in tuberculosis. Immunol. Rev. 262, 179-192 (2014).
    • (2014) Immunol. Rev , vol.262 , pp. 179-192
    • Srivastava, S.1    Ernst, J.D.2    Desvignes, L.3
  • 66
    • 84920057801 scopus 로고    scopus 로고
    • Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: Immunity interruptus
    • Behar, S. M., Carpenter, S. M., Booty, M. G., Barber, D. L. & Jayaraman, P. Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus. Semin. Immunol. 26, 559-577 (2014).
    • (2014) Semin. Immunol , vol.26 , pp. 559-577
    • Behar, S.M.1    Carpenter, S.M.2    Booty, M.G.3    Barber, D.L.4    Jayaraman, P.5
  • 68
    • 84938243731 scopus 로고    scopus 로고
    • Innate immune defenses in human tuberculosis: An overview of the interactions between Mycobacterium tuberculosis and innate immune cells
    • Sia, J. K., Georgieva, M. & Rengarajan, J. Innate immune defenses in human tuberculosis: an overview of the interactions between Mycobacterium tuberculosis and innate immune cells. J. Immunol. Res. 2015, 747543 (2015).
    • (2015) J. Immunol. Res , vol.2015 , pp. 747543
    • Sia, J.K.1    Georgieva, M.2    Rengarajan, J.3
  • 69
    • 85022333849 scopus 로고    scopus 로고
    • Digitally barcoding Mycobacterium tuberculosis reveals in vivo infection dynamics in the macaque model of tuberculosis
    • Martin, C. J. et al. Digitally barcoding Mycobacterium tuberculosis reveals in vivo infection dynamics in the macaque model of tuberculosis. mBio 8, e00312-17 (2017).
    • (2017) MBio , vol.8 , pp. e00312-e00317
    • Martin, C.J.1
  • 70
    • 84994882425 scopus 로고    scopus 로고
    • Macrophage epithelial reprogramming underlies mycobacterial granuloma formation and promotes infection
    • Cronan, M. R. et al. Macrophage epithelial reprogramming underlies mycobacterial granuloma formation and promotes infection. Immunity 45, 861-876 (2016).
    • (2016) Immunity , vol.45 , pp. 861-876
    • Cronan, M.R.1
  • 71
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent
    • Keane, J. et al. Tuberculosis associated with infliximab, a tumor necrosis factor α-neutralizing agent. N. Engl. J. Med. 345, 1098-1104 (2001).
    • (2001) N. Engl. J. Med , vol.345 , pp. 1098-1104
    • Keane, J.1
  • 72
    • 66449083072 scopus 로고    scopus 로고
    • + T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans
    • + T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans. J. Clin. Invest. 11 9, 1167-1177 (2009).
    • (2009) J. Clin. Invest , vol.11 , Issue.9 , pp. 1167-1177
    • Bruns, H.1
  • 73
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial
    • Maini, R. et al. Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 354, 1932-1939 (1999).
    • (1999) ATTRACT Study Group. Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1
  • 74
    • 75749099727 scopus 로고    scopus 로고
    • Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model
    • Lin, P. L. et al. Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model. Arthritis Rheum. 62, 340-350 (2010).
    • (2010) Arthritis Rheum , vol.62 , pp. 340-350
    • Lin, P.L.1
  • 75
    • 84964758662 scopus 로고    scopus 로고
    • Computational and empirical studies predict Mycobacterium tuberculosis-specific T cells as a biomarker for infection outcome
    • Marino, S. et al. Computational and empirical studies predict Mycobacterium tuberculosis-specific T cells as a biomarker for infection outcome. PLoS Comput. Biol. 12,e1004804 (2016).
    • (2016) PLoS Comput. Biol , vol.12 , pp. e1004804
    • Marino, S.1
  • 76
    • 84919495222 scopus 로고    scopus 로고
    • Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection
    • Marino, S. et al. Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection. Infect. Immun. 83, 324-338 (2015).
    • (2015) Infect. Immun , vol.83 , pp. 324-338
    • Marino, S.1
  • 77
    • 62149147607 scopus 로고    scopus 로고
    • Mathematical and computational approaches can complement experimental studies of host-pathogen interactions
    • Kirschner, D. E. & Linderman, J. J. Mathematical and computational approaches can complement experimental studies of host-pathogen interactions. Cell. Microbiol. 11, 531-539 (2009).
    • (2009) Cell. Microbiol , vol.11 , pp. 531-539
    • Kirschner, D.E.1    Linderman, J.J.2
  • 79
    • 0038496713 scopus 로고    scopus 로고
    • A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes
    • Lopez, B. et al. A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes. Clin. Exp. Immunol. 133, 30-37 (2003).
    • (2003) Clin. Exp. Immunol , vol.133 , pp. 30-37
    • Lopez, B.1
  • 80
    • 84903765139 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis strains of the modern sublineage of the Beijing family are more likely to display increased virulence than strains of the ancient sublineage
    • Ribeiro, S. C. et al. Mycobacterium tuberculosis strains of the modern sublineage of the Beijing family are more likely to display increased virulence than strains of the ancient sublineage. J. Clin. Microbiol. 52, 2615-2624 (2014).
    • (2014) J. Clin. Microbiol , vol.52 , pp. 2615-2624
    • Ribeiro, S.C.1
  • 81
    • 4544298326 scopus 로고    scopus 로고
    • A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response
    • Reed, M. B. et al. A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 431, 84-87 (2004).
    • (2004) Nature , vol.431 , pp. 84-87
    • Reed, M.B.1
  • 82
    • 4344592858 scopus 로고    scopus 로고
    • Correlation of virulence, lung pathology, bacterial load and delayed type hypersensitivity responses after infection with different Mycobacterium tuberculosis genotypes in a BALB/c mouse model
    • Dormans, J. et al. Correlation of virulence, lung pathology, bacterial load and delayed type hypersensitivity responses after infection with different Mycobacterium tuberculosis genotypes in a BALB/c mouse model. Clin. Exp. Immunol. 137, 460-468 (2004).
    • (2004) Clin. Exp. Immunol , vol.137 , pp. 460-468
    • Dormans, J.1
  • 83
    • 4544380418 scopus 로고    scopus 로고
    • Differential monocyte activation underlies strain-specific Mycobacterium tuberculosis pathogenesis
    • Manca, C. et al. Differential monocyte activation underlies strain-specific Mycobacterium tuberculosis pathogenesis. Infect. Immun. 72, 5511-5514 (2004).
    • (2004) Infect. Immun , vol.72 , pp. 5511-5514
    • Manca, C.1
  • 84
    • 79953274965 scopus 로고    scopus 로고
    • Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages
    • Portevin, D., Gagneux, S., Comas, I. & Young, D. Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages. PLoS Pathog. 7, e1001307 (2011).
    • (2011) PLoS Pathog , vol.7 , pp. e1001307
    • Portevin, D.1    Gagneux, S.2    Comas, I.3    Young, D.4
  • 85
    • 84879468975 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis strains are differentially recognized by TLRs with an impact on the immune response
    • Carmona, J. et al. Mycobacterium tuberculosis strains are differentially recognized by TLRs with an impact on the immune response. PLoS ONE 8, e67277 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e67277
    • Carmona, J.1
  • 86
    • 43249099379 scopus 로고    scopus 로고
    • Modelling within-host spatiotemporal dynamics of invasive bacterial disease
    • Grant, A. J. et al. Modelling within-host spatiotemporal dynamics of invasive bacterial disease. PLoS Biol. 6, e74 (2008).
    • (2008) PLoS Biol , vol.6 , pp. e74
    • Grant, A.J.1
  • 87
    • 84931565184 scopus 로고    scopus 로고
    • Bottlenecks in HIV-1 transmission: Insights from the study of founder viruses
    • Joseph, S. B., Swanstrom, R., Kashuba, A. D. & Cohen, M. S. Bottlenecks in HIV-1 transmission: insights from the study of founder viruses. Nat. Rev. Microbiol. 13, 414-425 (2015).
    • (2015) Nat. Rev. Microbiol , vol.13 , pp. 414-425
    • Joseph, S.B.1    Swanstrom, R.2    Kashuba, A.D.3    Cohen, M.S.4
  • 88
    • 79956371903 scopus 로고
    • Infective dose in pulmonary tuberculosis
    • Jacobs, A. L. Infective dose in pulmonary tuberculosis. Tubercle 22, 266-271 (1941).
    • (1941) Tubercle , vol.22 , pp. 266-271
    • Jacobs, A.L.1
  • 89
    • 84872513471 scopus 로고    scopus 로고
    • Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: A retrospective observational study
    • Walker, T. M. et al. Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Lancet Infect. Dis. 13,137-146 (2013).
    • (2013) Lancet Infect. Dis , vol.13 , pp. 137-146
    • Walker, T.M.1
  • 90
    • 84874261750 scopus 로고    scopus 로고
    • Inferring patient to patient transmission of Mycobacterium tuberculosis from whole genome sequencing data
    • Bryant, J. M. et al. Inferring patient to patient transmission of Mycobacterium tuberculosis from whole genome sequencing data. BMC Infect. Dis. 13, 110 (2013).
    • (2013) BMC Infect. Dis , vol.13 , pp. 110
    • Bryant, J.M.1
  • 91
    • 50349141358 scopus 로고
    • Treatment of staphylococcal infections with penicillin by intermittent sterilisation
    • Bigger, J. W. Treatment of staphylococcal infections with penicillin by intermittent sterilisation. Lancet 244, 497-500 (1944).
    • (1944) Lancet , vol.244 , pp. 497-500
    • Bigger, J.W.1
  • 92
    • 84896339295 scopus 로고    scopus 로고
    • Persisters and beyond: Mechanisms of phenotypic drug resistance and drug tolerance in bacteria
    • Kester, J. C. & Fortune, S. M. Persisters and beyond: mechanisms of phenotypic drug resistance and drug tolerance in bacteria. Crit. Rev. Biochem. Mol. Biol. 49, 91-101 (2014).
    • (2014) Crit. Rev. Biochem. Mol. Biol , vol.49 , pp. 91-101
    • Kester, J.C.1    Fortune, S.M.2
  • 93
    • 0031886212 scopus 로고    scopus 로고
    • How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis
    • Mitchison, D. A. How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis. Int. J. Tuberc. Lung Dis. 2, 10-15 (1998).
    • (1998) Int. J. Tuberc. Lung Dis , vol.2 , pp. 10-15
    • Mitchison, D.A.1
  • 94
    • 84907064892 scopus 로고    scopus 로고
    • How sisters grow apart: Mycobacterial growth and division
    • Kieser, K. J. & Rubin, E. J. How sisters grow apart: mycobacterial growth and division. Nat. Rev. Microbiol. 12, 550-562 (2014).
    • (2014) Nat. Rev. Microbiol , vol.12 , pp. 550-562
    • Kieser, K.J.1    Rubin, E.J.2
  • 95
    • 84871859996 scopus 로고    scopus 로고
    • Dynamic persistence of antibiotic-stressed mycobacteria
    • Wakamoto, Y. et al. Dynamic persistence of antibiotic-stressed mycobacteria. Science 339, 91-95 (2013).
    • (2013) Science , vol.339 , pp. 91-95
    • Wakamoto, Y.1
  • 96
    • 0032821532 scopus 로고    scopus 로고
    • Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications
    • Fox, W, Ellard, G. A. & Mitchison, D. A. Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications. Int. J. Tuberc. Lung Dis. 3, S231-S279 (1999).
    • (1999) Int. J. Tuberc. Lung Dis , vol.3 , pp. S231-S279
    • Fox Ellard W, G.A.1    Mitchison, D.A.2
  • 97
    • 0001907887 scopus 로고
    • A bacteriologic study of resected tuberculous lesions
    • Medlar, E. M., Bernstein, S. & Steward, D. M. A bacteriologic study of resected tuberculous lesions. Am. Rev. Tuberc. 66, 36-43 (1952).
    • (1952) Am. Rev. Tuberc , vol.66 , pp. 36-43
    • Medlar, E.M.1    Bernstein, S.2    Steward, D.M.3
  • 98
    • 0002887764 scopus 로고
    • A study of the tubercle bacillus in resected pulmonary lesions
    • Beck, F. & Yegian, D. A study of the tubercle bacillus in resected pulmonary lesions. Am. Rev. Tuberc. 66, 44-51 (1952).
    • (1952) Am. Rev. Tuberc , vol.66 , pp. 44-51
    • Beck, F.1    Yegian, D.2
  • 99
    • 0002952935 scopus 로고
    • Anatomical and bacteriological changes in tuberculous lesions under the influence of antibiotics and chemotherapy
    • Canetti, G. Anatomical and bacteriological changes in tuberculous lesions under the influence of antibiotics and chemotherapy. Bull. Int. Union Tuberc. 24, 144-240 (1954).
    • (1954) Bull. Int. Union Tuberc , vol.24 , pp. 144-240
    • Canetti, G.1
  • 100
    • 0000610130 scopus 로고
    • The bacteriology of resected tuberculous pulmonary lesions. I. the effect of interval between reversal of infectiousness and subsequent surgery
    • Salkin, D. & Wayne, L. G. The bacteriology of resected tuberculous pulmonary lesions. I. The effect of interval between reversal of infectiousness and subsequent surgery. Am. Rev. Tuberc. 74, 376-387 (1956).
    • (1956) Am. Rev. Tuberc , vol.74 , pp. 376-387
    • Salkin, D.1    Wayne, L.G.2
  • 101
    • 0034780485 scopus 로고    scopus 로고
    • Nonreplicating persistence of Mycobacterium tuberculosis
    • Wayne, L. G. & Sohaskey, C. D. Nonreplicating persistence of Mycobacterium tuberculosis. Annu. Rev. Microbiol. 55, 139-163 (2001).
    • (2001) Annu. Rev. Microbiol , vol.55 , pp. 139-163
    • Wayne, L.G.1    Sohaskey, C.D.2
  • 102
    • 85015991786 scopus 로고    scopus 로고
    • Acid-fast positive and acid-fast negative Mycobacterium tuberculosis: The Koch paradox
    • Vilcheze, C. & Kremer, L. Acid-fast positive and acid-fast negative Mycobacterium tuberculosis: the Koch paradox. Microbiol. Spectr. http://dx.doi.org/10.1128/ microbiolspec.TBTB2-0003-2015 (2017).
    • (2017) Microbiol. Spectr
    • Vilcheze, C.1    Kremer, L.2
  • 103
    • 0242552007 scopus 로고    scopus 로고
    • Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    • Seiler, P. et al. Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection. J. Infect. Dis. 188, 1326-1331 (2003).
    • (2003) J. Infect. Dis , vol.188 , pp. 1326-1331
    • Seiler, P.1
  • 104
    • 85015540298 scopus 로고    scopus 로고
    • Cortisone-forced reactivation of weakly acid fast positive Mycobacterium tuberculosis in Guinea pigs previously treated with chemotherapy
    • Obregon-Henao, A. et al. Cortisone-forced reactivation of weakly acid fast positive Mycobacterium tuberculosis in guinea pigs previously treated with chemotherapy. Mycobact. Dis. 2, 1000116 (2012).
    • (2012) Mycobact. Dis , vol.2 , pp. 1000116
    • Obregon-Henao, A.1
  • 106
    • 85007453750 scopus 로고    scopus 로고
    • Detection and quantification of differentially culturable tubercle bacteria in sputum from patients with tuberculosis
    • Chengalroyen, M. D. et al. Detection and quantification of differentially culturable tubercle bacteria in sputum from patients with tuberculosis. Am. J. Respir. Crit. Care Med. 194, 1532-1540 (2016).
    • (2016) Am. J. Respir. Crit. Care Med , vol.194 , pp. 1532-1540
    • Chengalroyen, M.D.1
  • 107
    • 43249101747 scopus 로고    scopus 로고
    • Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
    • Garton, N. J. et al. Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum. PLoS Med. 5, e75 (2008).
    • (2008) PLoS Med , vol.5 , pp. e75
    • Garton, N.J.1
  • 108
    • 84940756084 scopus 로고    scopus 로고
    • Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis during treatment of human tuberculosis
    • Walter, N. D. et al. Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis during treatment of human tuberculosis. J. Infect. Dis. 212, 990-998 (2015).
    • (2015) J. Infect. Dis , vol.212 , pp. 990-998
    • Walter, N.D.1
  • 109
    • 84962861468 scopus 로고    scopus 로고
    • Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy
    • Honeyborne, I. et al. Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy. BMC Med. 14, 68 (2016).
    • (2016) BMC Med , vol.14 , pp. 68
    • Honeyborne, I.1
  • 110
    • 84907584291 scopus 로고    scopus 로고
    • Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection
    • Sukumar, N., Tan, S., Aldridge, B. B. & Russell, D. G. Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection. PLoS Pathog. 10, e1004394 (2014).
    • (2014) PLoS Pathog , vol.10 , pp. e1004394
    • Sukumar, N.1    Tan, S.2    Aldridge, B.B.3    Russell, D.G.4
  • 111
    • 84920880232 scopus 로고    scopus 로고
    • Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms
    • Manina, G., Dhar, N. & McKinney, J. D. Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms. Cell Host Microbe 17, 32-46 (2015).
    • (2015) Cell Host Microbe , vol.17 , pp. 32-46
    • Manina, G.1    Dhar, N.2    McKinney, J.D.3
  • 112
    • 84908126151 scopus 로고    scopus 로고
    • Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis
    • Gillespie, S. H. et al. Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis. N. Engl. J. Med. 371, 1577-1587 (2014).
    • (2014) N. Engl. J. Med , vol.371 , pp. 1577-1587
    • Gillespie, S.H.1
  • 113
    • 80052393888 scopus 로고    scopus 로고
    • Nitroimidazoles for the treatment of TB: Past, present and future
    • Mukherjee, T. & Boshoff, H. Nitroimidazoles for the treatment of TB: past, present and future. Future Med. Chem. 3, 1427-1454 (2011).
    • (2011) Future Med. Chem , vol.3 , pp. 1427-1454
    • Mukherjee, T.1    Boshoff, H.2
  • 114
    • 33845323336 scopus 로고    scopus 로고
    • OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice
    • Matsumoto, M. et al. OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. PLoS Med. 3, e466 (2006).
    • (2006) PLoS Med , vol.3 , pp. e466
    • Matsumoto, M.1
  • 115
    • 0034702247 scopus 로고    scopus 로고
    • A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis
    • Stover, C. K. et al. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis. Nature 405, 962-966 (2000).
    • (2000) Nature , vol.405 , pp. 962-966
    • Stover, C.K.1
  • 116
    • 34248998479 scopus 로고    scopus 로고
    • Diarylquinolines target subunit c of mycobacterial ATP synthase
    • Koul, A. et al. Diarylquinolines target subunit c of mycobacterial ATP synthase. Nat. Chem. Biol. 3, 323-324 (2007).
    • (2007) Nat. Chem. Biol , vol.3 , pp. 323-324
    • Koul, A.1
  • 117
    • 84988811913 scopus 로고    scopus 로고
    • Inhibiting Mycobacterium tuberculosis within and without
    • Cole, S. T. Inhibiting Mycobacterium tuberculosis within and without. Phil. Trans. R. Soc. B Biol. Sci. http://dx.doi.org/10.1098/rstb.2015.0506 (2016).
    • (2016) Phil. Trans. R. Soc. B Biol. Sci
    • Cole, S.T.1
  • 118
    • 0037252098 scopus 로고    scopus 로고
    • The curious characteristics of pyrazinamide: A review
    • Zhang, Y. & Mitchison, D. The curious characteristics of pyrazinamide: a review. Int. J. Tuberc. Lung Dis. 7, 6-21 (2003).
    • (2003) Int. J. Tuberc. Lung Dis , vol.7 , pp. 6-21
    • Zhang, Y.1    Mitchison, D.2
  • 119
    • 84943664518 scopus 로고    scopus 로고
    • The association between sterilizing activity and drug distribution into tuberculosis lesions
    • Prideaux, B. et al. The association between sterilizing activity and drug distribution into tuberculosis lesions. Nat. Med. 21, 1223-1227 (2015).
    • (2015) Nat. Med , vol.21 , pp. 1223-1227
    • Prideaux, B.1
  • 120
    • 84973579918 scopus 로고    scopus 로고
    • The zebrafish breathes new life into the study of tuberculosis
    • Myllymaki, H., Bauerlein, C. A. & Ramet, M. The zebrafish breathes new life into the study of tuberculosis. Front. Immunol. 7, 196 (2016).
    • (2016) Front. Immunol , vol.7 , pp. 196
    • Myllymaki, H.1    Bauerlein, C.A.2    Ramet, M.3
  • 121
    • 84959529153 scopus 로고    scopus 로고
    • Mouse models of human TB pathology: Roles in the analysis of necrosis and the development of host-directed therapies
    • Kramnik, I. & Beamer, G. Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies. Semin. Immunopathol. 38, 221-237 (2016).
    • (2016) Semin. Immunopathol , vol.38 , pp. 221-237
    • Kramnik, I.1    Beamer, G.2
  • 123
    • 84923169949 scopus 로고    scopus 로고
    • Immunology studies in non-human primate models of tuberculosis
    • Flynn, J. L., Gideon, H. P., Mattila, J. T. & Lin, P. L. Immunology studies in non-human primate models of tuberculosis. Immunol. Rev. 264, 60-73 (2015).
    • (2015) Immunol. Rev , vol.264 , pp. 60-73
    • Flynn, J.L.1    Gideon, H.P.2    Mattila, J.T.3    Lin, P.L.4
  • 124
    • 84922962816 scopus 로고    scopus 로고
    • Monkey models of tuberculosis: Lessons learned
    • Pena, J. C. & Ho, W. Z. Monkey models of tuberculosis: lessons learned. Infect. Immun. 83, 852-862 (2015).
    • (2015) Infect. Immun , vol.83 , pp. 852-862
    • Pena, J.C.1    Ho, W.Z.2
  • 125
    • 77949758134 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load
    • Diedrich, C. R. et al. Reactivation of latent tuberculosis in cynomolgus macaques infected with SIV is associated with early peripheral T cell depletion and not virus load. PLoS ONE 5, e9611 (2010).
    • (2010) PLoS ONE , vol.5 , pp. e9611
    • Diedrich, C.R.1
  • 126
    • 84868134466 scopus 로고    scopus 로고
    • CD4 T cell depletion exacerbates acute Mycobacterium tuberculosis while reactivation of latent infection is dependent on severity of tissue depletion in cynomolgus macaques
    • Lin, P. L. et al. CD4 T cell depletion exacerbates acute Mycobacterium tuberculosis while reactivation of latent infection is dependent on severity of tissue depletion in cynomolgus macaques. AIDS Res. Hum. Retroviruses 28, 1693-1702 (2012).
    • (2012) AIDS Res. Hum. Retroviruses , vol.28 , pp. 1693-1702
    • Lin, P.L.1
  • 127
    • 84864817250 scopus 로고    scopus 로고
    • Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis
    • Shah, J. A. et al. Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis. J. Immunol. 189, 1737-1746 (2012).
    • (2012) J. Immunol , vol.189 , pp. 1737-1746
    • Shah, J.A.1
  • 128
    • 85028608930 scopus 로고    scopus 로고
    • A functional TOLLIP variant is associated with BCG-specific immune responses and tuberculosis
    • Shah, J. A. et al. A functional TOLLIP variant is associated with BCG-specific immune responses and tuberculosis. Am. J. Respir. Crit. Care Med. http:// dx.doi.org/10.1164/rccm.201611-2346OC (2017).
    • (2017) Am. J. Respir. Crit. Care Med
    • Shah, J.A.1
  • 129
    • 85014581607 scopus 로고    scopus 로고
    • The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes
    • Graustein, A. D. et al. The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes. Tuberculosis (Edinb.) 104, 38-45 (2017).
    • (2017) Tuberculosis (Edinb.) , vol.104 , pp. 38-45
    • Graustein, A.D.1
  • 130
    • 84994472454 scopus 로고    scopus 로고
    • Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype
    • Smith, C. M. et al. Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype. mBio 7, e01516-16 (2016).
    • (2016) MBio , vol.7 , pp. e01516-e01616
    • Smith, C.M.1
  • 131
    • 34548559007 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis, macrophages, and the innate immune response: Does common variation matter?
    • Berrington, W. R. & Hawn, T. R. Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter? Immunol. Rev. 219, 167-186 (2007).
    • (2007) Immunol. Rev , vol.219 , pp. 167-186
    • Berrington, W.R.1    Hawn, T.R.2
  • 132
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • Casanova, J. L. & Abel, L. Genetic dissection of immunity to mycobacteria: the human model. Annu. Rev. Immunol. 20, 581-620 (2002).
    • (2002) Annu. Rev. Immunol , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 133
    • 39549123040 scopus 로고    scopus 로고
    • Toll-like receptor polymorphisms and susceptibility to human disease
    • Misch, E. A. & Hawn, T. R. Toll-like receptor polymorphisms and susceptibility to human disease. Clin. Sci. (Lond.) 11 4, 347-360 (2008).
    • (2008) Clin. Sci. (Lond.) , vol.11 , Issue.4 , pp. 347-360
    • Misch, E.A.1    Hawn, T.R.2
  • 134
    • 14644441018 scopus 로고    scopus 로고
    • The Collaborative Cross, a community resource for the genetic analysis of complex traits
    • Churchill, G. A. et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat. Genet. 36, 1133-1137 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 1133-1137
    • Churchill, G.A.1
  • 135
    • 84863115856 scopus 로고    scopus 로고
    • The genome architecture of the Collaborative Cross mouse genetic reference population
    • Collaborative Cross Consortium
    • Collaborative Cross Consortium. The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics 190, 389-401 (2012).
    • (2012) Genetics , vol.190 , pp. 389-401


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