Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Antoniali, Giulia ^a   Serra, Fabrizio ^a,h   Lirussi, Lisa ^a,i   Tanaka, Mikiei ^b   D'Ambrosio, Chiara ^c   Zhang, Shiheng ^d   Radovic, Slobodanka ^e   Dalla, Emiliano ^f   Ciani, Yari ^f   Scaloni, Andrea ^c   Li, Mengxia ^d   Piazza, Silvano ^f,g   Tell, Gianluca ^a  

^a UNIVERSITY OF UDINE   (Italy)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c CNR   (Italy)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

^e C/o Parco Scientifico e Tecnologico L Danieli   (Italy)

^f Laboratorio Nazionale CIB   (Italy)

^g UNIVERSITY OF TRENTO   (Italy)

^h CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

ⁱ AKERSHUS UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; MICRORNA; MICRORNA 221; MICRORNA 222; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN DROSHA; RNA; UNCLASSIFIED DRUG; APEX1 PROTEIN, HUMAN; MIRN221 MICRORNA, HUMAN; MIRN222 MICRORNA, HUMAN; PTEN PROTEIN, HUMAN;

CANCER; DNA; ENZYME; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; METABOLISM; OXIDATIVE STRESS; PROTEIN; RNA;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; GENE EXPRESSION; GENOTOXICITY; HCT 116 CELL LINE; HELA CELL LINE; HUMAN; HUMAN TISSUE; INTERACTOME; MCF-7 CELL LINE; MOLECULAR BIOLOGY; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; RNA METABOLISM; RNA PROCESSING; TUMOR GENE; BRAIN TUMOR; BREAST TUMOR; COLORECTAL TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GLIOBLASTOMA; MALE; METABOLISM; NEOPLASM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERINE CERVIX TUMOR;

MAMMALIA;

BRAIN NEOPLASMS; BREAST NEOPLASMS; COLORECTAL NEOPLASMS; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HCT116 CELLS; HELA CELLS; HUMANS; MALE; MCF-7 CELLS; MICRORNAS; NEOPLASMS; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; UTERINE CERVICAL NEOPLASMS;

EID: 85030749992     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00842-8     Document Type: Article

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