Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w

Molecular Cell

Volumn 59, Issue 1, 2015, Pages 50-61

  Wang, Jian Xun ^a   Gao, Jie ^a   Ding, Su Ling ^a   Wang, Kun ^a   Jiao, Jian Qin ^a   Wang, Yin ^a   Sun, Teng ^a   Zhou, Lu Yu ^a   Long, Bo ^a   Zhang, Xiao Jie ^a   Li, Qian ^a   Liu, Jin Ping ^a   Feng, Chang ^a   Liu, Jia ^a   Gong, Ying ^a   Zhou, Zhixia ^a   Li, Pei Feng ^a  

^a QINGDAO UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 184; PROTEIN BCL W; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; BCL2L1 PROTEIN, MOUSE; BCL2L2 PROTEIN, MOUSE; MIRN184 MICRORNA, MOUSE; PROTEIN; PROTEIN BCL X; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; HEART INFARCTION; HEART MUSCLE CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MOUSE; MOUSE MODEL; NONHUMAN; OXIDATION; OXIDATIVE MODIFICATION; OXIDATIVE STRESS; PROTEIN TARGETING; RAT; RAT MODEL; REPERFUSION INJURY; TANDEM MASS SPECTROMETRY; ULTRAVIOLET SPECTROSCOPY; ANIMAL; C57BL MOUSE; CELL LINE; CYTOLOGY; GENETICS; HEART MUSCLE; MALE; METABOLISM; OXIDATION REDUCTION REACTION; RNA INTERFERENCE;

RATTUS;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELL LINE; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MYOCARDIUM; OXIDATION-REDUCTION; PROTEINS; RATS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84937162158     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.05.003     Document Type: Article

References (60)

1. Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
2. Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A., Brunskill E.W., Sayen M.R., Gottlieb R.A., Dorn G.W., et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005, 434:658-662.
3. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
4. Basson M. MicroRNAs loom large in the heart. Nat. Med. 2007, 13:541.
5. Bonauer A., Carmona G., Iwasaki M., Mione M., Koyanagi M., Fischer A., Burchfield J., Fox H., Doebele C., Ohtani K., et al. MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 2009, 324:1710-1713.
6. Chen C.H., Budas G.R., Churchill E.N., Disatnik M.H., Hurley T.D., Mochly-Rosen D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science 2008, 321:1493-1495.
7. Cheng K.C., Cahill D.S., Kasai H., Nishimura S., Loeb L.A. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G→T and A→C substitutions. J.Biol. Chem. 1992, 267:166-172.
8. Choi W.Y., Giraldez A.J., Schier A.F. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 2007, 318:271-274.
9. Ding Q., Markesbery W.R., Chen Q., Li F., Keller J.N. Ribosome dysfunction is an early event in Alzheimer's disease. J.Neurosci. 2005, 25:9171-9175.
10. Duggan S.T., Keating G.M. Pegylated liposomal doxorubicin: a review of its use in metastatic breast cancer, ovarian cancer, multiple myeloma and AIDS-related Kaposi's sarcoma. Drugs 2011, 71:2531-2558.
11. Fiala E.S., Conaway C.C., Mathis J.E. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989, 49:5518-5522.
12. Friedman R.C., Farh K.K., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19:92-105.
13. Giordano F.J. Oxygen, oxidative stress, hypoxia, and heart failure. J.Clin. Invest. 2005, 115:500-508.
14. Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
15. Henriksen T., Hillestrøm P.R., Poulsen H.E., Weimann A. Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2'-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry. Free Radic. Biol. Med. 2009, 47:629-635.
16. Hirotani S., Otsu K., Nishida K., Higuchi Y., Morita T., Nakayama H., Yamaguchi O., Mano T., Matsumura Y., Ueno H., et al. Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 2002, 105:509-515.
17. Honda K., Smith M.A., Zhu X., Baus D., Merrick W.C., Tartakoff A.M., Hattier T., Harris P.L., Siedlak S.L., Fujioka H., et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J.Biol. Chem. 2005, 280:20978-20986.
18. Kasai H., Chung M.H., Jones D.S., Inoue H., Ishikawa H., Kamiya H., Ohtsuka E., Nishimura S. 8-Hydroxyguanine, a DNA adduct formed by oxygen radicals: its implication on oxygen radical-involved mutagenesis/carcinogenesis. J.Toxicol. Sci. 1991, 16:95-105.
19. Kennedy L.J., Moore K., Caulfield J.L., Tannenbaum S.R., Dedon P.C. Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents. Chem. Res. Toxicol. 1997, 10:386-392.
20. Klungland A., Rosewell I., Hollenbach S., Larsen E., Daly G., Epe B., Seeberg E., Lindahl T., Barnes D.E. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc. Natl. Acad. Sci. USA 1999, 96:13300-13305.
21. Kong Q., Lin C.L. Oxidative damage to RNA: mechanisms, consequences, and diseases. Cell. Mol. Life Sci. 2010, 67:1817-1829.
22. Lee Y., Ahn C., Han J., Choi H., Kim J., Yim J., Lee J., Provost P., Rådmark O., Kim S., Kim V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003, 425:415-419.
23. Li L., Thomas R.M., Suzuki H., De Brabander J.K., Wang X., Harran P.G. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science 2004, 305:1471-1474.
24. Maga G., Villani G., Crespan E., Wimmer U., Ferrari E., Bertocci B., Hübscher U. 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. Nature 2007, 447:606-608.
25. Maki H., Sekiguchi M. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature 1992, 355:273-275.
26. Malayappan B., Garrett T.J., Segal M., Leeuwenburgh C. Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress. J.Chromatogr. A 2007, 1167:54-62.
27. McCord J.M. Oxygen-derived free radicals in postischemic tissue injury. N.Engl. J. Med. 1985, 312:159-163.
28. Miller D.M., Buettner G.R., Aust S.D. Transition metals as catalysts of "autoxidation" reactions. Free Radic. Biol. Med. 1990, 8:95-108.
29. Minotti G., Menna P., Salvatorelli E., Cairo G., Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 2004, 56:185-229.
30. Moriya M., Ou C., Bodepudi V., Johnson F., Takeshita M., Grollman A.P. Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E.coli. Mutat. Res. 1991, 254:281-288.
31. Ni T.T., Marsischky G.T., Kolodner R.D. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S.cerevisiae. Mol. Cell 1999, 4:439-444.
32. Nunomura A., Chiba S., Lippa C.F., Cras P., Kalaria R.N., Takeda A., Honda K., Smith M.A., Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol. Dis. 2004, 17:108-113.
33. Ørom U.A., Lund A.H. Isolation of microRNA targets using biotinylated synthetic microRNAs. Methods 2007, 43:162-165.
34. Palomeque J., Rueda O.V., Sapia L., Valverde C.A., Salas M., Petroff M.V., Mattiazzi A. Angiotensin II-induced oxidative stress resets the Ca2+ dependence of Ca2+-calmodulin protein kinase II and promotes a death pathway conserved across different species. Circ. Res. 2009, 105:1204-1212.
35. Petersen S.L., Wang L., Yalcin-Chin A., Li L., Peyton M., Minna J., Harran P., Wang X. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 2007, 12:445-456.
36. Plasterk R.H. Micro RNAs in animal development. Cell 2006, 124:877-881.
37. Ren X.P., Wu J., Wang X., Sartor M.A., Qian J., Jones K., Nicolaou P., Pritchard T.J., Fan G.C. MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20. Circulation 2009, 119:2357-2366.
38. Reth M. Hydrogen peroxide as second messenger in lymphocyte activation. Nat. Immunol. 2002, 3:1129-1134.
39. Shan X., Lin C.L. Quantification of oxidized RNAs in Alzheimer's disease. Neurobiol. Aging 2006, 27:657-662.
40. Shan X., Tashiro H., Lin C.L. The identification and characterization of oxidized RNAs in Alzheimer's disease. J.Neurosci. 2003, 23:4913-4921.
41. Shan X., Chang Y., Lin C.L. Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression. FASEB J. 2007, 21:2753-2764.
42. Shibutani S., Takeshita M., Grollman A.P. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. Nature 1991, 349:431-434.
43. Simpson P.J., Lucchesi B.R. Free radicals and myocardial ischemia and reperfusion injury. J.Lab. Clin. Med. 1987, 110:13-30.
44. Singal P.K., Iliskovic N. Doxorubicin-induced cardiomyopathy. N.Engl. J. Med. 1998, 339:900-905.
45. Singal P.K., Khaper N., Palace V., Kumar D. The role of oxidative stress in the genesis of heart disease. Cardiovasc. Res. 1998, 40:426-432.
46. Small E.M., Olson E.N. Pervasive roles of microRNAs in cardiovascular biology. Nature 2011, 469:336-342.
47. Stark A., Brennecke J., Bushati N., Russell R.B., Cohen S.M. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell 2005, 123:1133-1146.
48. Surmeier D.J., Guzman J.N., Sanchez-Padilla J., Goldberg J.A. The origins of oxidant stress in Parkinson's disease and therapeutic strategies. Antioxid. Redox Signal. 2011, 14:1289-1301.
49. Taddei F., Hayakawa H., Bouton M., Cirinesi A., Matic I., Sekiguchi M., Radman M. Counteraction by MutT protein of transcriptional errors caused by oxidative damage. Science 1997, 278:128-130.
50. Tanaka M., Chock P.B., Stadtman E.R. Oxidized messenger RNA induces translation errors. Proc. Natl. Acad. Sci. USA 2007, 104:66-71.
51. Valencia-Sanchez M.A., Liu J., Hannon G.J., Parker R. Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 2006, 20:515-524.
52. van Rooij E., Sutherland L.B., Qi X., Richardson J.A., Hill J., Olson E.N. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007, 316:575-579.
53. van Rooij E., Quiat D., Johnson B.A., Sutherland L.B., Qi X., Richardson J.A., Kelm R.J., Olson E.N. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev. Cell 2009, 17:662-673.
54. Varfolomeev E., Blankenship J.W., Wayson S.M., Fedorova A.V., Kayagaki N., Garg P., Zobel K., Dynek J.N., Elliott L.O., Wallweber H.J., et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007, 131:669-681.
55. Wamer W.G., Yin J.J., Wei R.R. Oxidative damage to nucleic acids photosensitized by titanium dioxide. Free Radic. Biol. Med. 1997, 23:851-858.
56. Wang J.X., Jiao J.Q., Li Q., Long B., Wang K., Liu J.P., Li Y.R., Li P.F. miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat. Med. 2011, 17:71-78.
57. Woo D.K., Shadel G.S. Mitochondrial stress signals revise an old aging theory. Cell 2011, 144:11-12.
58. Yang J., Maity B., Huang J., Gao Z., Stewart A., Weiss R.M., Anderson M.E., Fisher R.A. G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin. Cancer Res. 2013, 73:1662-1667.
59. Zawia N.H., Lahiri D.K., Cardozo-Pelaez F. Epigenetics, oxidative stress, and Alzheimer disease. Free Radic. Biol. Med. 2009, 46:1241-1249.
60. Zhao Y., Ransom J.F., Li A., Vedantham V., von Drehle M., Muth A.N., Tsuchihashi T., McManus M.T., Schwartz R.J., Srivastava D. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 2007, 129:303-317.