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Volumn 17, Issue 1, 2012, Pages 65-77

The miR-200 and miR-221/222 microRNA families: Opposing effects on epithelial identity

Author keywords

Breast cancer; EMT; MET; miR 200; miR 221; miR 222

Indexed keywords

MICRORNA; MICRORNA 200; MICRORNA 221; MICRORNA 222; UNCLASSIFIED DRUG;

EID: 84858703841     PISSN: 10833021     EISSN: 15737039     Source Type: Journal    
DOI: 10.1007/s10911-012-9244-6     Document Type: Review
Times cited : (111)

References (142)
  • 1
    • 33846277696 scopus 로고    scopus 로고
    • Repression of protein synthesis by miRNAs: how many mechanisms?
    • DOI 10.1016/j.tcb.2006.12.007, PII S096289240600359X
    • Pillai RS, Bhattacharyya SN, Filipowicz W. Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol. 2007;17(3):118-26. (Pubitemid 46357525)
    • (2007) Trends in Cell Biology , vol.17 , Issue.3 , pp. 118-126
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Filipowicz, W.3
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-33.
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 33846905270 scopus 로고    scopus 로고
    • Maternally imprinted microRNAs are differentially expressed during mouse and human lung development
    • DOI 10.1002/dvdy.21047
    • Williams AE, Moschos SA, Perry MM, Barnes PJ, Lindsay MA. Maternally imprinted microRNAs are differentially expressed during mouse and human lung development. Developmental Dynamics: An Official Publication of the American Association of Anatomists. 2007;236(2):572-80. (Pubitemid 46233301)
    • (2007) Developmental Dynamics , vol.236 , Issue.2 , pp. 572-580
    • Williams, A.E.1    Moschos, S.A.2    Perry, M.M.3    Barnes, P.J.4    Lindsay, M.A.5
  • 4
    • 44349138854 scopus 로고    scopus 로고
    • Piecing together the mosaic of early mammalian development through microRNAs
    • Blakaj A, Lin H. Piecing together the mosaic of early mammalian development through microRNAs. J Biol Chem. 2008;283 (15):9505-8.
    • (2008) J Biol Chem , vol.283 , Issue.15 , pp. 9505-9508
    • Blakaj, A.1    Lin, H.2
  • 5
    • 39749110083 scopus 로고    scopus 로고
    • Small non-coding RNAs in animal development
    • DOI 10.1038/nrm2347, PII NRM2347
    • Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol. 2008;9(3):219-30. (Pubitemid 351301826)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.3 , pp. 219-230
    • Stefani, G.1    Slack, F.J.2
  • 6
    • 77954860342 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
    • Micalizzi DS, Farabaugh SM, Ford HL. Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia. 2010;15 (2):117-34.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 7
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • DOI 10.1016/j.ceb.2005.08.001, PII S0955067405001043
    • Huber MA, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol. 2005;17(5):548-58. (Pubitemid 41267170)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.5 SPEC. ISS. , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 8
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002;2(6):442-54.
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 9
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelialmesenchymal transitions. Nat Rev Mol Cell Biol. 2006;7(2):131-42. (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 10
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
    • DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
    • Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell. 2008;14(6):818-29. (Pubitemid 351757205)
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 11
    • 34249289041 scopus 로고    scopus 로고
    • Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • DOI 10.1038/nrc2131, PII NRC2131
    • Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer. 2007;7(6):415-28. (Pubitemid 46809165)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.6 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 12
    • 0033568198 scopus 로고    scopus 로고
    • New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites
    • DOI 10.1093/emboj/18.18.5073
    • Remacle JE, Kraft H, LerchnerW,Wuytens G, Collart C, Verschueren K, et al. New mode of DNA binding of multi-zinc finger transcription factors: deltaEF1 family members bind with two hands to two target sites. EMBO J. 1999;18(18):5073-84. (Pubitemid 29443809)
    • (1999) EMBO Journal , vol.18 , Issue.18 , pp. 5073-5084
    • Remacle, J.E.1    Kraft, H.2    Lerchner, W.3    Wuytens, G.4    Collart, C.5    Verschueren, K.6    Smith, J.C.7    Huylebroeck, D.8
  • 14
    • 20144388095 scopus 로고    scopus 로고
    • DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
    • DOI 10.1038/sj.onc.1208429
    • Eger A, Aigner K, Sonderegger S, Dampier B, Oehler S, Schreiber M, et al. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene. 2005;24(14):2375-85. (Pubitemid 40546696)
    • (2005) Oncogene , vol.24 , Issue.14 , pp. 2375-2385
    • Eger, A.1    Aigner, K.2    Sonderegger, S.3    Dampier, B.4    Oehler, S.5    Schreiber, M.6    Berx, G.7    Cano, A.8    Beug, H.9    Foisner, R.10
  • 16
    • 34548496683 scopus 로고    scopus 로고
    • Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial-mesenchymal transition induced by TGF-beta
    • DOI 10.1091/mbc.E07-03-0249
    • Shirakihara T, Saitoh M, Miyazono K. Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta. Mol Biol Cell. 2007;18(9):3533-44. (Pubitemid 47378691)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.9 , pp. 3533-3544
    • Shirakihara, T.1    Saitoh, M.2    Miyazono, K.3
  • 17
    • 34548565806 scopus 로고    scopus 로고
    • Overexpression of the MicroRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin
    • DOI 10.1158/0008-5472.CAN-07-1058
    • Hurteau GJ, Carlson JA, Spivack SD, Brock GJ. Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. Cancer Res. 2007;67(17):7972-6. (Pubitemid 47395127)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 7972-7976
    • Hurteau, G.J.1    Carlson, J.A.2    Spivack, S.D.3    Brock, G.J.4
  • 19
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • DOI 10.1101/gad.1640608
    • Park S-M, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008;22 (7):894-907. (Pubitemid 351482843)
    • (2008) Genes and Development , vol.22 , Issue.7 , pp. 894-907
    • Park, S.-M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 20
    • 79959216175 scopus 로고    scopus 로고
    • TRPS1 targeting by miR-221/222 promotes the epithelial-tomesenchymal transition in breast cancer
    • Stinson S, Lackner MR, Adai AT, Yu N, Kim H-J, O'Brien C, et al. TRPS1 targeting by miR-221/222 promotes the epithelial-tomesenchymal transition in breast cancer. Sci Signal. 2011;4(177): ra41.
    • (2011) Sci Signal , vol.4 , Issue.177
    • Stinson, S.1    Lackner, M.R.2    Adai, A.T.3    Yu, N.4    Kim, H.-J.5    O'Brien, C.6
  • 22
    • 77955172153 scopus 로고    scopus 로고
    • miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer
    • Uhlmann S, Zhang JD, Schwäger A, Mannsperger H, Riazalhosseini Y, Burmester S, et al. miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer. Oncogene. 2010;29(30):4297-306.
    • (2010) Oncogene , vol.29 , Issue.30 , pp. 4297-4306
    • Uhlmann, S.1    Zhang, J.D.2    Schwäger, A.3    Mannsperger, H.4    Riazalhosseini, Y.5    Burmester, S.6
  • 23
    • 67650561891 scopus 로고    scopus 로고
    • Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression
    • Hurteau GJ, Carlson JA, Roos E, Brock GJ. Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression. Cell Cycle. 2009;8(13):2064-9.
    • (2009) Cell Cycle , vol.8 , Issue.13 , pp. 2064-2069
    • Hurteau, G.J.1    Carlson, J.A.2    Roos, E.3    Brock, G.J.4
  • 25
    • 77954427807 scopus 로고    scopus 로고
    • MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells
    • Hu M, Xia M, Chen X, Lin Z, Xu Y, Ma Y, et al. MicroRNA-141 regulates Smad interacting protein 1 (SIP1) and inhibits migration and invasion of colorectal cancer cells. Dig Dis Sci. 2010;55 (8):2365-72.
    • (2010) Dig Dis Sci , vol.55 , Issue.8 , pp. 2365-2372
    • Hu, M.1    Xia, M.2    Chen, X.3    Lin, Z.4    Xu, Y.5    Ma, Y.6
  • 26
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag A, et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol. 2009;11(12):1487-95.
    • (2009) Nat Cell Biol , vol.11 , Issue.12 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3    Schmalhofer, O.4    Zhu, F.5    Sonntag, A.6
  • 27
    • 79953329774 scopus 로고    scopus 로고
    • The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice
    • Yang Y, Ahn Y-H, Gibbons DL, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121(4):1373-85.
    • (2011) J Clin Invest , vol.121 , Issue.4 , pp. 1373-1385
    • Yang, Y.1    Ahn, Y.-H.2    Gibbons, D.L.3    Zang, Y.4    Lin, W.5    Thilaganathan, N.6
  • 28
    • 79955373842 scopus 로고    scopus 로고
    • Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b
    • Wang Z, Zhao Y, Smith E, Goodall GJ, Drew PA, Brabletz T, et al. Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b. Toxicol Sci. 2011;121(1):110-22.
    • (2011) Toxicol Sci , vol.121 , Issue.1 , pp. 110-122
    • Wang, Z.1    Zhao, Y.2    Smith, E.3    Goodall, G.J.4    Drew, P.A.5    Brabletz, T.6
  • 29
    • 77951945516 scopus 로고    scopus 로고
    • Identification of microRNA profiles in docetaxel-resistant human non-small cell lung carcinoma cells (SPC-A1)
    • Rui W, Bing F, Hai-Zhu S, Wei D, Long-Bang C. Identification of microRNA profiles in docetaxel-resistant human non-small cell lung carcinoma cells (SPC-A1). J Cell Mol Med. 2010;14(1-2):206-14.
    • (2010) J Cell Mol Med , vol.14 , Issue.1-2 , pp. 206-214
    • Rui, W.1    Bing, F.2    Hai-Zhu, S.3    Wei, D.4    Long-Bang, C.5
  • 30
    • 77957280345 scopus 로고    scopus 로고
    • Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer
    • Ceppi P, Mudduluru G, Kumarswamy R, Rapa I, Scagliotti GV, Papotti M, et al. Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer. Mol Cancer Res. 2010;8(9):1207-16.
    • (2010) Mol Cancer Res , vol.8 , Issue.9 , pp. 1207-1216
    • Ceppi, P.1    Mudduluru, G.2    Kumarswamy, R.3    Rapa, I.4    Scagliotti, G.V.5    Papotti, M.6
  • 31
    • 70450263322 scopus 로고    scopus 로고
    • The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion
    • Sossey-Alaoui K, Bialkowska K, Plow EF. The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion. J Biol Chem. 2009;284(48):33019-29.
    • (2009) J Biol Chem , vol.284 , Issue.48 , pp. 33019-33029
    • Sossey-Alaoui, K.1    Bialkowska, K.2    Plow, E.F.3
  • 32
    • 79955102595 scopus 로고    scopus 로고
    • Targets of miR-200c mediate suppression of cell motility and anoikis resistance
    • Howe EN, Cochrane DR, Richer JK. Targets of miR-200c mediate suppression of cell motility and anoikis resistance. Breast Cancer Res. 2011;13(2):R45.
    • (2011) Breast Cancer Res , vol.13 , Issue.2
    • Howe, E.N.1    Cochrane, D.R.2    Richer, J.K.3
  • 33
    • 78449298671 scopus 로고    scopus 로고
    • MicroRNA- 200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells
    • Xia W, Li J, Chen L, Huang B, Li S, Yang G, et al. MicroRNA- 200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells. Mol Cell Biochem. 2010;344(1-2):261-6.
    • (2010) Mol Cell Biochem , vol.344 , Issue.1-2 , pp. 261-266
    • Xia, W.1    Li, J.2    Chen, L.3    Huang, B.4    Li, S.5    Yang, G.6
  • 34
    • 71149108895 scopus 로고    scopus 로고
    • Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K
    • Hyun S, Lee JH, Jin H, Nam J, Namkoong B, Lee G, et al. Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K. Cell. 2009;139(6):1096-108.
    • (2009) Cell , vol.139 , Issue.6 , pp. 1096-1108
    • Hyun, S.1    Lee, J.H.2    Jin, H.3    Nam, J.4    Namkoong, B.5    Lee, G.6
  • 35
    • 4344627055 scopus 로고    scopus 로고
    • Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
    • Douma S, Van Laar T, Zevenhoven J, Meuwissen R, Van Garderen E, Peeper DS. Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature. 2004;430(7003):1034-9.
    • (2004) Nature , vol.430 , Issue.7003 , pp. 1034-1039
    • Douma, S.1    Van Laar, T.2    Zevenhoven, J.3    Meuwissen, R.4    Van Garderen, E.5    Peeper, D.S.6
  • 36
    • 34447123807 scopus 로고    scopus 로고
    • Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis
    • DOI 10.1158/0008-5472.CAN-07-0121
    • Geiger TR, Peeper DS. Critical role for TrkB kinase function in anoikis suppression, tumorigenesis, and metastasis. Cancer Res. 2007;67(13):6221-9. (Pubitemid 47037503)
    • (2007) Cancer Research , vol.67 , Issue.13 , pp. 6221-6229
    • Geiger, T.R.1    Peeper, D.S.2
  • 37
    • 39749121408 scopus 로고    scopus 로고
    • Dieldrin promotes resistance to anoikis in breast cancer cells in vitro
    • Cameron HL, Foster WG. Dieldrin promotes resistance to anoikis in breast cancer cells in vitro. Reprod Toxicol. 2008;25(2):256-62.
    • (2008) Reprod Toxicol , vol.25 , Issue.2 , pp. 256-262
    • Cameron, H.L.1    Foster, W.G.2
  • 38
    • 67650045932 scopus 로고    scopus 로고
    • A Twist- Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis
    • Smit MA, Geiger TR, Song J-Y, Gitelman I, Peeper DS. A Twist- Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis. Mol Cell Biol. 2009;29(13):3722-37.
    • (2009) Mol Cell Biol , vol.29 , Issue.13 , pp. 3722-3737
    • Smit, M.A.1    Geiger, T.R.2    Song, J.-Y.3    Gitelman, I.4    Peeper, D.S.5
  • 39
    • 66849140943 scopus 로고    scopus 로고
    • MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
    • Cochrane DR, Spoelstra NS, Howe EN, Nordeen SK, Richer JK. MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. Mol Cancer Ther. 2009;8(5):1055-66.
    • (2009) Mol Cancer Ther , vol.8 , Issue.5 , pp. 1055-1066
    • Cochrane, D.R.1    Spoelstra, N.S.2    Howe, E.N.3    Nordeen, S.K.4    Richer, J.K.5
  • 40
    • 77954863985 scopus 로고    scopus 로고
    • Loss of miR- 200c: A marker of aggressiveness and chemoresistance in female reproductive cancers
    • Cochrane DR, Howe EN, Spoelstra NS, Richer JK. Loss of miR- 200c: A marker of aggressiveness and chemoresistance in female reproductive cancers. J Oncol. 2010;2010:821717.
    • (2010) J Oncol , vol.2010 , pp. 821717
    • Cochrane, D.R.1    Howe, E.N.2    Spoelstra, N.S.3    Richer, J.K.4
  • 42
    • 41349121211 scopus 로고    scopus 로고
    • Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin
    • Umezu T, Shibata K, Kajiyama H, Terauchi M, Ino K, Nawa A, et al. Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin. Int J Gynecol Pathol. 2008;27(2):207-12.
    • (2008) Int J Gynecol Pathol , vol.27 , Issue.2 , pp. 207-212
    • Umezu, T.1    Shibata, K.2    Kajiyama, H.3    Terauchi, M.4    Ino, K.5    Nawa, A.6
  • 43
    • 75549087583 scopus 로고    scopus 로고
    • Class III beta-tubulin expression and in vitro resistance to microtubule targeting agents
    • Stengel C, Newman SP, Leese MP, Potter BVL, Reed MJ, Purohit A. Class III beta-tubulin expression and in vitro resistance to microtubule targeting agents. Br J Cancer. 2010;102(2):316-24.
    • (2010) Br J Cancer , vol.102 , Issue.2 , pp. 316-324
    • Stengel, C.1    Newman, S.P.2    Leese, M.P.3    Potter, B.V.L.4    Reed, M.J.5    Purohit, A.6
  • 46
    • 77649191871 scopus 로고    scopus 로고
    • Microtubules and resistance to tubulin-binding agents
    • Kavallaris M. Microtubules and resistance to tubulin-binding agents. Nat Rev Cancer. 2010;10(3):194-204.
    • (2010) Nat Rev Cancer , vol.10 , Issue.3 , pp. 194-204
    • Kavallaris, M.1
  • 47
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer. 2010;127(8):1785-94.
    • (2010) Int J Cancer , vol.127 , Issue.8 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 48
    • 84868002446 scopus 로고    scopus 로고
    • Down-regulation of microRNA-200c is associated with drug resistance in human breast cancer
    • (Northwood, London, England) [Internet]. Nov 19 [cited 2011 Dec 12];Available from
    • Chen J, Tian W, Cai H, He H, Deng Y. Down-regulation of microRNA-200c is associated with drug resistance in human breast cancer. Medical Oncology (Northwood, London, England) [Internet]. 2011 Nov 19 [cited 2011 Dec 12];Available from: http:// www.ncbi.nlm.nih.gov/pubmed/22101791.
    • (2011) Medical Oncology
    • Chen, J.1    Tian, W.2    Cai, H.3    He, H.4    Deng, Y.5
  • 49
    • 69349087756 scopus 로고    scopus 로고
    • miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy
    • Adam L, Zhong M, Choi W, Qi W, Nicoloso M, Arora A, et al. miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res. 2009;15 (16):5060-72.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5060-5072
    • Adam, L.1    Zhong, M.2    Choi, W.3    Qi, W.4    Nicoloso, M.5    Arora, A.6
  • 50
    • 77955507555 scopus 로고    scopus 로고
    • miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1
    • Schickel R, Park S-M, Murmann AE, Peter ME. miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1. Mol Cell. 2010;38(6):908-15.
    • (2010) Mol Cell , vol.38 , Issue.6 , pp. 908-915
    • Schickel, R.1    Park, S.-M.2    Murmann, A.E.3    Peter, M.E.4
  • 52
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • DOI 10.1038/nrc1997, PII NRC1997
    • Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer. 2006;6(11):857-66. (Pubitemid 44629897)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 53
    • 68749117685 scopus 로고    scopus 로고
    • Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype
    • Grelier G, Voirin N, Ay A-S, Cox DG, Chabaud S, Treilleux I, et al. Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype. Br J Cancer. 2009;101(4):673-83.
    • (2009) Br J Cancer , vol.101 , Issue.4 , pp. 673-683
    • Grelier, G.1    Voirin, N.2    Ay, A.-S.3    Cox, D.G.4    Chabaud, S.5    Treilleux, I.6
  • 54
    • 77957902732 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells
    • Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, et al. Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS One. 2010;5(8): e12445.
    • (2010) PLoS One , vol.5 , Issue.8
    • Kong, D.1    Banerjee, S.2    Ahmad, A.3    Li, Y.4    Wang, Z.5    Sethi, S.6
  • 55
    • 79951810835 scopus 로고    scopus 로고
    • Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
    • Vallejo DM, Caparros E, Dominguez M. Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells. EMBO J. 2011;30(4):756-69.
    • (2011) EMBO J , vol.30 , Issue.4 , pp. 756-769
    • Vallejo, D.M.1    Caparros, E.2    Dominguez, M.3
  • 56
    • 68049114782 scopus 로고    scopus 로고
    • Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
    • Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138(3):592-603.
    • (2009) Cell , vol.138 , Issue.3 , pp. 592-603
    • Shimono, Y.1    Zabala, M.2    Cho, R.W.3    Lobo, N.4    Dalerba, P.5    Qian, D.6
  • 57
    • 77956547097 scopus 로고    scopus 로고
    • Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells
    • Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Mol Cell. 2010;39(5):761-72.
    • (2010) Mol Cell , vol.39 , Issue.5 , pp. 761-772
    • Iliopoulos, D.1    Lindahl-Allen, M.2    Polytarchou, C.3    Hirsch, H.A.4    Tsichlis, P.N.5    Struhl, K.6
  • 58
    • 77951248184 scopus 로고    scopus 로고
    • E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells
    • Tryndyak VP, Beland FA, Pogribny IP. E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells. Int J Cancer. 2010;126(11):2575-83.
    • (2010) Int J Cancer , vol.126 , Issue.11 , pp. 2575-2583
    • Tryndyak, V.P.1    Beland, F.A.2    Pogribny, I.P.3
  • 59
    • 79955497173 scopus 로고    scopus 로고
    • Phosphoglucose isomerase/autocrine motility factor mediates epithelial-mesenchymal transition regulated by miR-200 in breast cancer cells
    • Ahmad A, Aboukameel A, Kong D, Wang Z, Sethi S, Chen W, et al. Phosphoglucose isomerase/autocrine motility factor mediates epithelial- mesenchymal transition regulated by miR-200 in breast cancer cells. Cancer Res. 2011;71(9):3400-9.
    • (2011) Cancer Res , vol.71 , Issue.9 , pp. 3400-3409
    • Ahmad, A.1    Aboukameel, A.2    Kong, D.3    Wang, Z.4    Sethi, S.5    Chen, W.6
  • 60
    • 70349645539 scopus 로고    scopus 로고
    • miR- 200 enhances mouse breast cancer cell colonization to form distant metastases
    • Dykxhoorn DM, Wu Y, Xie H, Yu F, Lal A, Petrocca F, et al. miR- 200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One. 2009;4(9):e7181.
    • (2009) PLoS One , vol.4 , Issue.9
    • Dykxhoorn, D.M.1    Wu, Y.2    Xie, H.3    Yu, F.4    Lal, A.5    Petrocca, F.6
  • 61
    • 80052470207 scopus 로고    scopus 로고
    • Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
    • Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celià- Terrassa T, et al. Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med. 2011;17(9):1101-8.
    • (2011) Nat Med , vol.17 , Issue.9 , pp. 1101-1108
    • Korpal, M.1    Ell, B.J.2    Buffa, F.M.3    Ibrahim, T.4    Blanco, M.A.5    Celià- Terrassa, T.6
  • 63
    • 65649087527 scopus 로고    scopus 로고
    • Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues
    • Hui ABY, Shi W, Boutros PC, Miller N, Pintilie M, Fyles T, et al. Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest. 2009;89 (5):597-606.
    • (2009) Lab Invest , vol.89 , Issue.5 , pp. 597-606
    • Hui, A.B.Y.1    Shi, W.2    Boutros, P.C.3    Miller, N.4    Pintilie, M.5    Fyles, T.6
  • 64
    • 80051989350 scopus 로고    scopus 로고
    • MicroRNA profiles of healthy basal and luminal mammary epithelial cells are distinct and reflected in different breast cancer subtypes
    • Bockmeyer CL, Christgen M, Müller M, Fischer S, Ahrens P, Länger F, et al. MicroRNA profiles of healthy basal and luminal mammary epithelial cells are distinct and reflected in different breast cancer subtypes. Breast Cancer Res Treat. 2011;130 (3):735-45.
    • (2011) Breast Cancer Res Treat , vol.130 , Issue.3 , pp. 735-745
    • Bockmeyer, C.L.1    Christgen, M.2    Müller, M.3    Fischer, S.4    Ahrens, P.5    Länger, F.6
  • 65
    • 70349134366 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets
    • Baffa R, Fassan M, Volinia S, O'Hara B, Liu C-G, Palazzo JP, et al. MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J Pathol. 2009;219(2):214-21.
    • (2009) J Pathol , vol.219 , Issue.2 , pp. 214-221
    • Baffa, R.1    Fassan, M.2    Volinia, S.3    O'Hara, B.4    Liu, C.-G.5    Palazzo, J.P.6
  • 66
    • 79955419817 scopus 로고    scopus 로고
    • Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs
    • Gill JG, Langer EM, Lindsley RC, Cai M, Murphy TL, Kyba M, et al. Snail and the microRNA-200 family act in opposition to regulate epithelial-to- mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells. 2011;29(5):764-76.
    • (2011) Stem Cells , vol.29 , Issue.5 , pp. 764-776
    • Gill, J.G.1    Langer, E.M.2    Lindsley, R.C.3    Cai, M.4    Murphy, T.L.5    Kyba, M.6
  • 67
    • 70350302617 scopus 로고    scopus 로고
    • Mycregulated microRNAs attenuate embryonic stem cell differentiation
    • Lin C-H, Jackson AL, Guo J, Linsley PS, Eisenman RN. Mycregulated microRNAs attenuate embryonic stem cell differentiation. EMBO J. 2009;28(20):3157-70.
    • (2009) EMBO J , vol.28 , Issue.20 , pp. 3157-3170
    • Lin, C.-H.1    Jackson, A.L.2    Guo, J.3    Linsley, P.S.4    Eisenman, R.N.5
  • 68
    • 70349142665 scopus 로고    scopus 로고
    • Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
    • Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, et al. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev. 2009;23(18):2140-51.
    • (2009) Genes Dev , vol.23 , Issue.18 , pp. 2140-2151
    • Gibbons, D.L.1    Lin, W.2    Creighton, C.J.3    Rizvi, Z.H.4    Gregory, P.A.5    Goodall, G.J.6
  • 69
    • 79955954699 scopus 로고    scopus 로고
    • An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
    • Gregory PA, Bracken CP, Smith E, Bert AG,Wright JA, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22(10):1686-98.
    • (2011) Mol Biol Cell , vol.22 , Issue.10 , pp. 1686-1698
    • Gregory, P.A.1    Bracken, C.P.2    Smith, E.3    Bert, A.G.4    Wright, J.A.5    Roslan, S.6
  • 70
    • 78649644924 scopus 로고    scopus 로고
    • MicroRNA profiling reveals two distinct p53-relatedhuman pluripotent stem cell states
    • Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, et al. MicroRNA profiling reveals two distinct p53-relatedhuman pluripotent stem cell states. Cell Stem Cell. 2010;7 (6):671-81.
    • (2010) Cell Stem Cell , vol.7 , Issue.6 , pp. 671-681
    • Neveu, P.1    Kye, M.J.2    Qi, S.3    Buchholz, D.E.4    Clegg, D.O.5    Sahin, M.6
  • 71
    • 77956320116 scopus 로고    scopus 로고
    • Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
    • Samavarchi-Tehrani P, Golipour A, David L, Sung H-K, Beyer TA, Datti A, et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell. 2010;7(1):64-77.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 64-77
    • Samavarchi-Tehrani, P.1    Golipour, A.2    David, L.3    Sung, H.-K.4    Beyer, T.A.5    Datti, A.6
  • 72
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG,Wang J, Shannon MF, et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 2008;68(19):7846-54.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6
  • 73
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • DOI 10.1038/embor.2008.74, PII EMBOR200874
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008;9(6):582-9. (Pubitemid 351772923)
    • (2008) EMBO Reports , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 74
    • 79960391940 scopus 로고    scopus 로고
    • miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells
    • Eades G, Yao Y, Yang M, Zhang Y, Chumsri S, Zhou Q. miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cells. J Biol Chem. 2011;286(29):25992- 6002.
    • (2011) J Biol Chem , vol.286 , Issue.29 , pp. 25992-26002
    • Eades, G.1    Yao, Y.2    Yang, M.3    Zhang, Y.4    Chumsri, S.5    Zhou, Q.6
  • 75
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem. 2008;283(22):14910-4.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 76
    • 79960705270 scopus 로고    scopus 로고
    • TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/ Slug
    • Slabáková E, Pernicová Z, Slavíč ková E, Staršíchová A, Kozubík A, Souček K. TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/ Slug. Prostate. 2011;71(12):1332-43.
    • (2011) Prostate , vol.71 , Issue.12 , pp. 1332-1343
    • Slabáková, E.1    Pernicová, Z.2    Slavíč ková, E.3    Staršíchová, A.4    Kozubík, A.5    Souček, K.6
  • 77
    • 84859913271 scopus 로고    scopus 로고
    • Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis
    • Internet. Aug 29 [cited 2011 Dec 13];Available from
    • Davalos V, Moutinho C, Villanueva A, Boque R, Silva P, Carneiro F, et al. Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis. Oncogene [Internet]. 2011 Aug 29 [cited 2011 Dec 13];Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 21874049.
    • (2011) Oncogene
    • Davalos, V.1    Moutinho, C.2    Villanueva, A.3    Boque, R.4    Silva, P.5    Carneiro, F.6
  • 78
    • 77649251655 scopus 로고    scopus 로고
    • Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells
    • Vrba L, Jensen TJ, Garbe JC, Heimark RL, Cress AE, Dickinson S, et al. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells. PLoS One. 2010;5 (1):e8697.
    • (2010) PLoS One , vol.5 , Issue.1
    • Vrba, L.1    Jensen, T.J.2    Garbe, J.C.3    Heimark, R.L.4    Cress, A.E.5    Dickinson, S.6
  • 79
    • 79551469293 scopus 로고    scopus 로고
    • Coordinated epigenetic repression of the miR- 200 family and miR-205 in invasive bladder cancer
    • Wiklund ED, Bramsen JB, Hulf T, Dyrskjøt L, Ramanathan R, Hansen TB, et al. Coordinated epigenetic repression of the miR- 200 family and miR-205 in invasive bladder cancer. Int J Cancer. 2011;128(6):1327-34.
    • (2011) Int J Cancer , vol.128 , Issue.6 , pp. 1327-1334
    • Wiklund, E.D.1    Bramsen, J.B.2    Hulf, T.3    Dyrskjøt, L.4    Ramanathan, R.5    Hansen, T.B.6
  • 80
    • 82455168080 scopus 로고    scopus 로고
    • The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma
    • Yuan J-H, Yang F, Chen B-F, Lu Z, Huo X-S, Zhou W-P, et al. The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. Hepatology. 2011;54(6):2025-35.
    • (2011) Hepatology , vol.54 , Issue.6 , pp. 2025-2035
    • Yuan, J.-H.1    Yang, F.2    Chen, B.-F.3    Lu, Z.4    Huo, X.-S.5    Zhou, W.-P.6
  • 81
    • 69249156944 scopus 로고    scopus 로고
    • miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells
    • Kong D, Li Y, Wang Z, Banerjee S, Ahmad A, Kim H-RC, et al. miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells. Stem Cells. 2009;27(8):1712-21.
    • (2009) Stem Cells , vol.27 , Issue.8 , pp. 1712-1721
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Ahmad, A.5    Kim, H.-R.C.6
  • 82
    • 69249096109 scopus 로고    scopus 로고
    • Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
    • Li Y, VandenBoom 2nd TG, Kong D, Wang Z, Ali S, Philip PA, et al. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res. 2009;69(16):6704-12.
    • (2009) Cancer Res , vol.69 , Issue.16 , pp. 6704-6712
    • Li, Y.1    VandenBoom II, T.G.2    Kong, D.3    Wang, Z.4    Ali, S.5    Philip, P.A.6
  • 83
    • 79954576652 scopus 로고    scopus 로고
    • EMT and stem cell-like properties associated with miR- 205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells
    • Tellez CS, Juri DE, Do K, Bernauer AM, Thomas CL, Damiani LA, et al. EMT and stem cell-like properties associated with miR- 205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Res. 2011;71(8):3087-97.
    • (2011) Cancer Res , vol.71 , Issue.8 , pp. 3087-3097
    • Tellez, C.S.1    Juri, D.E.2    Do, K.3    Bernauer, A.M.4    Thomas, C.L.5    Damiani, L.A.6
  • 84
    • 79952382550 scopus 로고    scopus 로고
    • Antitumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer
    • Bao B, Ali S, Kong D, Sarkar SH, Wang Z, Banerjee S, et al. Antitumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. PLoS One. 2011;6(3):e17850.
    • (2011) PLoS One , vol.6 , Issue.3
    • Bao, B.1    Ali, S.2    Kong, D.3    Sarkar, S.H.4    Wang, Z.5    Banerjee, S.6
  • 86
    • 79952283482 scopus 로고    scopus 로고
    • p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
    • Chang C-J, Chao C-H, Xia W, Yang J-Y, Xiong Y, Li C-W, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011;13 (3):317-23.
    • (2011) Nat Cell Biol , vol.13 , Issue.3 , pp. 317-323
    • Chang, C.-J.1    Chao, C.-H.2    Xia, W.3    Yang, J.-Y.4    Xiong, Y.5    Li, C.-W.6
  • 87
    • 79956143950 scopus 로고    scopus 로고
    • p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
    • KimT, Veronese A, Pichiorri F, Lee TJ, Jeon Y-J, Volinia S, et al. p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2. J Exp Med. 2011;208(5):875-83.
    • (2011) J Exp Med , vol.208 , Issue.5 , pp. 875-883
    • Kim, T.1    Veronese, A.2    Pichiorri, F.3    Lee, T.J.4    Jeon, Y.-J.5    Volinia, S.6
  • 88
    • 84855865135 scopus 로고    scopus 로고
    • An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription
    • Internet. Sep 14 [cited 2011 Dec 13]; Available from
    • Knouf EC, Garg K, Arroyo JD, Correa Y, Sarkar D, Parkin RK, et al. An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription. Nucleic Acids Research [Internet]. 2011 Sep 14 [cited 2011 Dec 13]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 21917857.
    • (2011) Nucleic Acids Research
    • Knouf, E.C.1    Garg, K.2    Arroyo, J.D.3    Correa, Y.4    Sarkar, D.5    Parkin, R.K.6
  • 90
    • 84869225629 scopus 로고    scopus 로고
    • MiR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2
    • (Northwood, London, England) [Internet]. Apr 13 [cited 2011 Dec 13];Available from
    • Zheng C, Yinghao S, Li J. MiR-221 expression affects invasion potential of human prostate carcinoma cell lines by targeting DVL2. Medical Oncology (Northwood, London, England) [Internet].2011 Apr 13 [cited 2011 Dec 13];Available from: http://www. ncbi.nlm.nih.gov/pubmed/21487968.
    • (2011) Medical Oncology
    • Zheng, C.1    Yinghao, S.2    Li, J.3
  • 91
    • 79960670757 scopus 로고    scopus 로고
    • miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3
    • Li X, Zhang Y, Zhang H, Liu X, Gong T, Li M, et al. miRNA-223 promotes gastric cancer invasion and metastasis by targeting tumor suppressor EPB41L3. Mol Cancer Res. 2011;9(7):824-33.
    • (2011) Mol Cancer Res , vol.9 , Issue.7 , pp. 824-833
    • Li, X.1    Zhang, Y.2    Zhang, H.3    Liu, X.4    Gong, T.5    Li, M.6
  • 93
    • 77952386365 scopus 로고    scopus 로고
    • miR-146b is highly expressed in adult papillary thyroid carcinomas with high risk features including extrathyroidal invasion and the BRAF(V600E) mutation
    • Chou C-K, Chen R-F, Chou F-F, Chang H-W, Chen Y-J, Lee Y-F, et al. miR-146b is highly expressed in adult papillary thyroid carcinomas with high risk features including extrathyroidal invasion and the BRAF(V600E) mutation. Thyroid. 2010;20(5):489-94.
    • (2010) Thyroid , vol.20 , Issue.5 , pp. 489-494
    • Chou, C.-K.1    Chen, R.-F.2    Chou, F.-F.3    Chang, H.-W.4    Chen, Y.-J.5    Lee, Y.-F.6
  • 94
    • 79952432768 scopus 로고    scopus 로고
    • MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma
    • Sun K, Wang W, Zeng J-jie, Wu C-tang, Lei S-tong, Li Gxin. MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. Acta Pharmacol Sin. 2011;32 (3):375-84.
    • (2011) Acta Pharmacol Sin , vol.32 , Issue.3 , pp. 375-384
    • Sun, K.1    Wang, W.2    Zeng, J.-J.3    Wu, C.-T.4    Lei, S.-T.5    Li, G.6
  • 96
    • 77951540421 scopus 로고    scopus 로고
    • Differential expression of specific microRNA and their targets in acute myeloid leukemia
    • Cammarata G, Augugliaro L, Salemi D, Agueli C, La Rosa M, Dagnino L, et al. Differential expression of specific microRNA and their targets in acute myeloid leukemia. Am J Hematol. 2010;85(5):331-9.
    • (2010) Am J Hematol , vol.85 , Issue.5 , pp. 331-339
    • Cammarata, G.1    Augugliaro, L.2    Salemi, D.3    Agueli, C.4    La Rosa, M.5    Dagnino, L.6
  • 97
    • 63449123568 scopus 로고    scopus 로고
    • MiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31
    • Veerla S, Lindgren D, Kvist A, Frigyesi A, Staaf J, Persson H, et al. MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31. Int J Cancer. 2009;124(9):2236-42.
    • (2009) Int J Cancer , vol.124 , Issue.9 , pp. 2236-2242
    • Veerla, S.1    Lindgren, D.2    Kvist, A.3    Frigyesi, A.4    Staaf, J.5    Persson, H.6
  • 98
    • 69549111268 scopus 로고    scopus 로고
    • Analysis of miR-221 and p27 expression in human gliomas
    • Lu X, Zhao P, Zhang C, Fu Z, Chen Y, Lu A, et al. Analysis of miR-221 and p27 expression in human gliomas. Mol Med Report. 2009;2(4):651-6.
    • (2009) Mol Med Report , vol.2 , Issue.4 , pp. 651-656
    • Lu, X.1    Zhao, P.2    Zhang, C.3    Fu, Z.4    Chen, Y.5    Lu, A.6
  • 100
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA- 221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • Zhao J-J, Lin J, Yang H, Kong W, He L, Ma X, et al. MicroRNA- 221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem. 2008;283(45):31079-86.
    • (2008) J Biol Chem , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.-J.1    Lin, J.2    Yang, H.3    Kong, W.4    He, L.5    Ma, X.6
  • 102
    • 80052223077 scopus 로고    scopus 로고
    • microRNA-associated progression pathways andpotential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer
    • Buffa FM, Camps C, Winchester L, Snell CE, Gee HE, Sheldon H, et al. microRNA-associated progression pathways andpotential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancer. Cancer Res. 2011;71(17):5635-45.
    • (2011) Cancer Res , vol.71 , Issue.17 , pp. 5635-5645
    • Buffa, F.M.1    Camps, C.2    Winchester, L.3    Snell, C.E.4    Gee, H.E.5    Sheldon, H.6
  • 103
    • 70349941429 scopus 로고    scopus 로고
    • Expression profile of microRNAs in c-Myc induced mouse mammary tumors
    • Sun Y, Wu J, Wu S-hung, Thakur A, Bollig A, Huang Y, et al. Expression profile of microRNAs in c-Myc induced mouse mammary tumors. Breast Cancer Res Treat. 2009;118(1):185-96.
    • (2009) Breast Cancer Res Treat , vol.118 , Issue.1 , pp. 185-196
    • Sun, Y.1    Wu, J.2    Wu, S.-H.3    Thakur, A.4    Bollig, A.5    Huang, Y.6
  • 104
    • 82455208876 scopus 로고    scopus 로고
    • Distinct expressions of microRNAs that directly target estrogen receptor α in human breast cancer
    • Yoshimoto N, Toyama T, Takahashi S, Sugiura H, Endo Y, Iwasa M, et al. Distinct expressions of microRNAs that directly target estrogen receptor α in human breast cancer. Breast Cancer Res Treat. 2011;130(1):331-9.
    • (2011) Breast Cancer Res Treat , vol.130 , Issue.1 , pp. 331-339
    • Yoshimoto, N.1    Toyama, T.2    Takahashi, S.3    Sugiura, H.4    Endo, Y.5    Iwasa, M.6
  • 105
    • 77955429106 scopus 로고    scopus 로고
    • MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN
    • Chun-Zhi Z, Lei H, An-Ling Z, Yan-Chao F, Xiao Y, Guang-Xiu W, et al. MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN. BMC Cancer. 2010;10:367.
    • (2010) BMC Cancer , vol.10 , pp. 367
    • Chun-Zhi, Z.1    Lei, H.2    An-Ling, Z.3    Yan-Chao, F.4    Xiao, Y.5    Guang-Xiu, W.6
  • 106
    • 69349083676 scopus 로고    scopus 로고
    • MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality
    • Gramantieri L, Fornari F, Ferracin M, Veronese A, Sabbioni S, Calin GA, et al. MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. Clin Cancer Res. 2009;15(16):5073-81.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5073-5081
    • Gramantieri, L.1    Fornari, F.2    Ferracin, M.3    Veronese, A.4    Sabbioni, S.5    Calin, G.A.6
  • 107
    • 84857924822 scopus 로고    scopus 로고
    • Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs
    • Internet. May 7 [cited 2011 Dec 14];Available from
    • Guttilla IK, Phoenix KN, Hong X, Tirnauer JS, Claffey KP, White BA. Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs. Breast Cancer Res. Treat. [Internet]. 2011 May 7 [cited 2011 Dec 14];Available from: http://www.ncbi.nlm.nih. gov/pubmed/21553120.
    • (2011) Breast Cancer Res. Treat
    • Guttilla, I.K.1    Phoenix, K.N.2    Hong, X.3    Tirnauer, J.S.4    Claffey, K.P.5    White, B.A.6
  • 109
    • 78650217926 scopus 로고    scopus 로고
    • Quantitative immunohistochemical analysis and prognostic significance of TRPS-1, a new GATA transcription factor family member, in breast cancer
    • Chen JQ, Litton J, Xiao L, Zhang H-Z, Warneke CL, Wu Y, et al. Quantitative immunohistochemical analysis and prognostic significance of TRPS-1, a new GATA transcription factor family member, in breast cancer. Horm Cancer. 2010;1(1):21-33.
    • (2010) Horm Cancer , vol.1 , Issue.1 , pp. 21-33
    • Chen, J.Q.1    Litton, J.2    Xiao, L.3    Zhang, H.-Z.4    Warneke, C.L.5    Wu, Y.6
  • 110
    • 80053576554 scopus 로고    scopus 로고
    • MicroRNAs miR-221 and miR-222: A new level of regulation in aggressive breast cancer
    • Shah MY, Calin GA. MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer. Genome Med. 2011;3(8):56.
    • (2011) Genome Med , vol.3 , Issue.8 , pp. 56
    • Shah, M.Y.1    Calin, G.A.2
  • 112
    • 52949127316 scopus 로고    scopus 로고
    • MiR-221 controls CDKN1C/p57 and CDKN1B/ p27 expression in human hepatocellular carcinoma
    • Fornari F, Gramantieri L, Ferracin M, Veronese A, Sabbioni S, Calin GA, et al. MiR-221 controls CDKN1C/p57 and CDKN1B/ p27 expression in human hepatocellular carcinoma. Oncogene. 2008;27(43):5651-61.
    • (2008) Oncogene , vol.27 , Issue.43 , pp. 5651-5661
    • Fornari, F.1    Gramantieri, L.2    Ferracin, M.3    Veronese, A.4    Sabbioni, S.5    Calin, G.A.6
  • 114
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(Kip1) tumor suppressor by miR- 221 and miR-222 promotes cancer cell proliferation
    • le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, et al. Regulation of the p27(Kip1) tumor suppressor by miR- 221 and miR-222 promotes cancer cell proliferation. EMBO J. 2007;26(15):3699-708.
    • (2007) EMBO J , vol.26 , Issue.15 , pp. 3699-3708
    • Le Sage, C.1    Nagel, R.2    Egan, D.A.3    Schrier, M.4    Mesman, E.5    Mangiola, A.6
  • 116
    • 77953004738 scopus 로고    scopus 로고
    • MicroRNA and proliferation control in chronic lymphocytic leukemia: Functional relationship between miR-221/222 cluster and p27
    • Frenquelli M, Muzio M, Scielzo C, Fazi C, Scarfò L, Rossi C, et al. MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27. Blood. 2010;115(19):3949-59.
    • (2010) Blood , vol.115 , Issue.19 , pp. 3949-3959
    • Frenquelli, M.1    Muzio, M.2    Scielzo, C.3    Fazi, C.4    Scarfò, L.5    Rossi, C.6
  • 117
    • 58149240996 scopus 로고    scopus 로고
    • The inhibition of the highly expressed miR-221 and miR- 222 impairs the growth of prostate carcinoma xenografts in mice
    • MercatelliN, CoppolaV, Bonci D,Miele F, Costantini A, Guadagnoli M, et al. The inhibition of the highly expressed miR-221 and miR- 222 impairs the growth of prostate carcinoma xenografts in mice. PLoS One. 2008;3(12):e4029.
    • (2008) PLoS One , vol.3 , Issue.12
    • Mercatelli, N.1    Coppola, V.2    Bonci, D.3    Miele, F.4    Costantini, A.5    Guadagnoli, M.6
  • 118
    • 67649424199 scopus 로고    scopus 로고
    • Cosuppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo
    • Zhang C, Kang C, You Y, Pu P, Yang W, Zhao P, et al. Cosuppression of miR-221/222 cluster suppresses human glioma cell growth by targeting p27kip1 in vitro and in vivo. Int J Oncol. 2009;34(6):1653-60.
    • (2009) Int J Oncol , vol.34 , Issue.6 , pp. 1653-1660
    • Zhang, C.1    Kang, C.2    You, Y.3    Pu, P.4    Yang, W.5    Zhao, P.6
  • 119
    • 84255192032 scopus 로고    scopus 로고
    • miR-221 Silencing Blocks Hepatocellular Carcinoma and Promotes Survival
    • Park J-K, Kogure T, Nuovo GJ, Jiang J, He L, Kim JH, et al. miR-221 Silencing Blocks Hepatocellular Carcinoma and Promotes Survival. Cancer Res. 2011;71(24):7608-16.
    • (2011) Cancer Res , vol.71 , Issue.24 , pp. 7608-7616
    • Park, J.-K.1    Kogure, T.2    Nuovo, G.J.3    Jiang, J.4    He, L.5    Kim, J.H.6
  • 120
    • 78650842745 scopus 로고    scopus 로고
    • MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer
    • Phila
    • Chen Y, Zaman MS, Deng G, Majid S, Saini S, Liu J, et al. MicroRNAs 221/222 and genistein-mediated regulation of ARHI tumor suppressor gene in prostate cancer. Cancer Prev Res (Phila). 2011;4(1):76-86.
    • (2011) Cancer Prev Res , vol.4 , Issue.1 , pp. 76-86
    • Chen, Y.1    Zaman, M.S.2    Deng, G.3    Majid, S.4    Saini, S.5    Liu, J.6
  • 124
    • 70349904531 scopus 로고    scopus 로고
    • Antisense inhibition of microRNA-21 or -221 arrests cell cycle, induces apoptosis, and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma
    • Park J-K, Lee EJ, Esau C, Schmittgen TD. Antisense inhibition of microRNA-21 or -221 arrests cell cycle, induces apoptosis, and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma. Pancreas. 2009;38(7):e190-199.
    • (2009) Pancreas , vol.38 , Issue.7
    • Park, J.-K.1    Lee, E.J.2    Esau, C.3    Schmittgen, T.D.4
  • 125
    • 77954378366 scopus 로고    scopus 로고
    • MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    • Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, et al. MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J Biol Chem. 2010;285 (28):21496-507.
    • (2010) J Biol Chem , vol.285 , Issue.28 , pp. 21496-21507
    • Zhou, M.1    Liu, Z.2    Zhao, Y.3    Ding, Y.4    Liu, H.5    Xi, Y.6
  • 126
    • 77749340705 scopus 로고    scopus 로고
    • miR- 221/222 promote malignant progression of glioma through activation of the Akt pathway
    • Zhang J, Han L, Ge Y, Zhou X, Zhang A, Zhang C, et al. miR- 221/222 promote malignant progression of glioma through activation of the Akt pathway. Int J Oncol. 2010;36(4):913-20.
    • (2010) Int J Oncol , vol.36 , Issue.4 , pp. 913-920
    • Zhang, J.1    Han, L.2    Ge, Y.3    Zhou, X.4    Zhang, A.5    Zhang, C.6
  • 127
    • 3242712110 scopus 로고    scopus 로고
    • Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: Subgroup analysis from celecoxib antiaromatase neoadjuvant trial
    • DOI 10.1158/1078-0432.CCR-04-0057
    • Zhu L, Chow LWC, Loo WTY, Guan X-Y, Toi M. Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial. Clin Cancer Res. 2004;10 (14):4639-44. (Pubitemid 38955513)
    • (2004) Clinical Cancer Research , vol.10 , Issue.14 , pp. 4639-4644
    • Zhu, L.1    Chow, L.W.C.2    Loo, W.T.Y.3    Guan, X.-Y.4    Toi, M.5
  • 128
    • 0034761909 scopus 로고    scopus 로고
    • The predictive value of HER2 in breast cancer
    • DOI 10.1159/000055405
    • Piccart M, Lohrisch C, Di Leo A, Larsimont D. The predictive value of HER2 in breast cancer. Oncology. 2001;61 Suppl 2:73-82. (Pubitemid 33033428)
    • (2001) Oncology , vol.61 , Issue.SUPPL. 2 , pp. 73-82
    • Piccart, M.1    Lohrisch, C.2    Di, L.A.3    Larsimont, D.4
  • 129
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B, Roy S, Datta J, Shapiro CL, et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem. 2008;283 (44):29897-903.
    • (2008) J Biol Chem , vol.283 , Issue.44 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3    Roy, S.4    Datta, J.5    Shapiro, C.L.6
  • 130
    • 82755176300 scopus 로고    scopus 로고
    • Anti-microRNA-222 (Anti-miR-222) and -181B Suppress Growth of Tamoxifen-resistant Xenografts in Mouse by Targeting TIMP3 Protein and Modulating Mitogenic Signal
    • Lu Y, Roy S, Nuovo G, Ramaswamy B, Miller T, Shapiro C, et al. Anti-microRNA-222 (Anti-miR-222) and -181B Suppress Growth of Tamoxifen-resistant Xenografts in Mouse by Targeting TIMP3 Protein and Modulating Mitogenic Signal. J Biol Chem. 2011;286(49):42292-302.
    • (2011) J Biol Chem , vol.286 , Issue.49 , pp. 42292-42302
    • Lu, Y.1    Roy, S.2    Nuovo, G.3    Ramaswamy, B.4    Miller, T.5    Shapiro, C.6
  • 131
    • 79952281614 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
    • Rao X, Di Leva G, Li M, Fang F, Devlin C, Hartman-Frey C, et al. MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene. 2011;30(9):1082-97.
    • (2011) Oncogene , vol.30 , Issue.9 , pp. 1082-1097
    • Rao, X.1    Di Leva, G.2    Li, M.3    Fang, F.4    Devlin, C.5    Hartman-Frey, C.6
  • 134
    • 0032771824 scopus 로고    scopus 로고
    • 1 on breast cancer cell proliferation are mediated through regulation of aberrant nuclear factor-kappaB/Rel expression
    • Sovak MA, Arsura M, Zanieski G, Kavanagh KT, Sonenshein GE. The inhibitory effects of transforming growth factor beta1 on breast cancer cell proliferation are mediated through regulation ofaberrant nuclear factor-kappaB/Rel expression. Cell Growth Differ. 1999;10(8):537-44. (Pubitemid 29399061)
    • (1999) Cell Growth and Differentiation , vol.10 , Issue.8 , pp. 537-544
    • Sovak, M.A.1    Arsura, M.2    Zanieski, G.3    Kavanagh, K.T.4    Sonenshein, G.E.5
  • 135
    • 78449253475 scopus 로고    scopus 로고
    • Down-regulation of microRNAs 222/221 in acute myelogenous leukemia with deranged core-binding factor subunits
    • Brioschi M, Fischer J, Cairoli R, Rossetti S, Pezzetti L, Nichelatti M, et al. Down-regulation of microRNAs 222/221 in acute myelogenous leukemia with deranged core-binding factor subunits. Neoplasia. 2010;12(11):866-76.
    • (2010) Neoplasia , vol.12 , Issue.11 , pp. 866-876
    • Brioschi, M.1    Fischer, J.2    Cairoli, R.3    Rossetti, S.4    Pezzetti, L.5    Nichelatti, M.6
  • 137
    • 14844290887 scopus 로고    scopus 로고
    • FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells
    • DOI 10.1038/sj.onc.1208312
    • Belguise K, Kersual N, Galtier F, Chalbos D. FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells. Oncogene. 2005;24(8):1434-44. (Pubitemid 40343123)
    • (2005) Oncogene , vol.24 , Issue.8 , pp. 1434-1444
    • Belguise, K.1    Kersual, N.2    Galtier, F.3    Chalbos, D.4
  • 138
    • 76349121520 scopus 로고    scopus 로고
    • The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression
    • Luo YP, Zhou H, Krueger J, Kaplan C, Liao D, Markowitz D, et al. The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression. Oncogene. 2010;29(5):662-73.
    • (2010) Oncogene , vol.29 , Issue.5 , pp. 662-673
    • Luo, Y.P.1    Zhou, H.2    Krueger, J.3    Kaplan, C.4    Liao, D.5    Markowitz, D.6
  • 139
    • 70350464482 scopus 로고    scopus 로고
    • Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells
    • Ndlovu'Matladi N, Van Lint C, Van Wesemael K, Callebert P, Chalbos D, Haegeman G, et al. Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells. Mol Cell Biol. 2009;29 (20):5488-504.
    • (2009) Mol Cell Biol , vol.29 , Issue.20 , pp. 5488-5504
    • Ndlovu'Matladi, N.1    Van Lint, C.2    Van Wesemael, K.3    Callebert, P.4    Chalbos, D.5    Haegeman, G.6
  • 141
    • 77958558613 scopus 로고    scopus 로고
    • TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
    • Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin Y-L, et al. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 2010;467(7318):986-90.
    • (2010) Nature , vol.467 , Issue.7318 , pp. 986-990
    • Su, X.1    Chakravarti, D.2    Cho, M.S.3    Liu, L.4    Gi, Y.J.5    Lin, Y.-L.6


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