Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress

EMBO Journal

Volumn 32, Issue 24, 2013, Pages 3192-3205

  Chang, Jonathan ^a,b,c   Davis Dusenbery, Brandi N ^b   Kashima, Risa ^a   Jiang, Xuan ^a   Marathe, Nisha ^a   Sessa, Roberto ^a   Louie, Justin ^a   Gu, Wei ^d   Lagna, Giorgio ^a,b,e   Hata, Akiko ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apoptosis; Drosha; MiRNA; P53

Indexed keywords

ACYLTRANSFERASE; ANTISENSE OLIGONUCLEOTIDE; CAMPTOTHECIN; CASPASE 3; CASPASE 7; DACTINOMYCIN; MICRORNA; MICRORNA 103; MICRORNA 16; MICRORNA 203; NUTLIN 3; PROTEIN BAX; PROTEIN BCL W; PROTEIN P53; PROTEIN P68; PUMA PROTEIN; RNA HELICASE; SMAD PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ACETYLATION; AMINO ACID SUBSTITUTION; APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CELL CYCLE ARREST; CELL DEATH; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVITY; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; RNA PROCESSING; TRANSCRIPTION INITIATION;

ACETYLATION; APOPTOSIS REGULATORY PROTEINS; CAMPTOTHECIN; CELL SURVIVAL; DNA DAMAGE; HCT116 CELLS; HISTONE ACETYLTRANSFERASES; HUMANS; IMIDAZOLES; MICRORNAS; PIPERAZINES; PROMOTER REGIONS, GENETIC; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84890571063     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.242     Document Type: Article

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