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Volumn 452, Issue 3, 2013, Pages 545-557

Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin)

Author keywords

Apurinic apyrimidinic endonuclease 1 (APE1); Nucleophosmin (NPM1); Phylogenesis; Protein DNA interaction; Protein protein interaction

Indexed keywords

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; NUCLEOPHOSMIN;

EID: 84878400065     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121277     Document Type: Article
Times cited : (38)

References (45)
  • 1
    • 13244299159 scopus 로고    scopus 로고
    • A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells
    • DOI 10.1016/j.molcel.2004.12.029, PII S1097276505010397
    • Fung, H. and Demple, B. (2005) A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells. Mol. Cell 17, 463-470 (Pubitemid 40193316)
    • (2005) Molecular Cell , vol.17 , Issue.3 , pp. 463-470
    • Fung, H.1    Demple, B.2
  • 2
    • 0347504848 scopus 로고    scopus 로고
    • Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene
    • DOI 10.1093/emboj/cdg595
    • Bhakat, K. K., Izumi, T., Yang, S. H., Hazra, T. K. and Mitra, S. (2003) Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene. EMBO J. 1, 6299-6309 (Pubitemid 37522587)
    • (2003) EMBO Journal , vol.22 , Issue.23 , pp. 6299-6309
    • Bhakat, K.K.1    Izumi, T.2    Yang, S.-H.3    Hazra, T.K.4    Mitra, S.5
  • 4
    • 14044269479 scopus 로고    scopus 로고
    • The intracellular localization of APE1/Ref-1: More than a passive phenomenon?
    • DOI 10.1089/ars.2005.7.367
    • Tell, G., Damante, G., Caldwell, D. and Kelley, M. R. (2005) The intracellular localization of APE1/Ref-1: more than a passive phenomenon? Antioxid. Redox Signaling 7, 367-384 (Pubitemid 40279805)
    • (2005) Antioxidants and Redox Signaling , vol.7 , Issue.3-4 , pp. 367-384
    • Tell, G.1    Damante, G.2    Caldwell, D.3    Kelley, M.R.4
  • 6
    • 84961981834 scopus 로고    scopus 로고
    • Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases
    • DOI 10.1093/nar/26.11.2771
    • Erzberger, J. P., Barsky, D., Schärer, O. D., Colvin, M. E. and Wilson, III, D. M. (1998) Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases. Nucleic Acids Res. 26, 2771-2778 (Pubitemid 28297395)
    • (1998) Nucleic Acids Research , vol.26 , Issue.11 , pp. 2771-2778
    • Erzberger, J.P.1    Barsky, D.2    Scharer, O.D.3    Colvin, M.E.4    Wilson III, D.M.5
  • 7
    • 33645225808 scopus 로고    scopus 로고
    • Nucleotide sequence and DNA secondary structure, as well as replication protein A, modulate the single-stranded abasic endonuclease activity of APE1
    • DOI 10.1074/jbc.M511004200
    • Fan, J., Matsumoto, Y. and Wilson, III, D. M. (2006) Nucleotide sequence and DNA secondary structure, as well as replication protein A, modulate the single-stranded abasic endonuclease activity of APE1. J. Biol. Chem. 281, 3889-3898 (Pubitemid 43847812)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.7 , pp. 3889-3898
    • Fan, J.1    Matsumoto, Y.2    Wilson III, D.M.3
  • 8
    • 1842735418 scopus 로고    scopus 로고
    • Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA
    • DOI 10.1016/j.dnarep.2004.01.010, PII S1568786404000291
    • Marenstein, D. R., Wilson, III, D. M. and Teebor, G. W. (2004) Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA. DNA Repair 3, 527-533 (Pubitemid 38482027)
    • (2004) DNA Repair , vol.3 , Issue.5 , pp. 527-533
    • Marenstein, D.R.1    Wilson III, D.M.2    Teebor, G.W.3
  • 9
    • 79251647522 scopus 로고    scopus 로고
    • Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1
    • Sengupta, S., Mantha, A. K., Mitra, S. and Bhakat, K. K. (2011) Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1. Oncogene 30, 482-493
    • (2011) Oncogene , vol.30 , pp. 482-493
    • Sengupta, S.1    Mantha, A.K.2    Mitra, S.3    Bhakat, K.K.4
  • 10
    • 73549091674 scopus 로고    scopus 로고
    • Intrusion of a DNA repair protein in the RNome world: Is this the beginning of a new era?
    • Tell, G., Wilson, III, D. M. and Lee, C. H. (2010) Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era? Mol. Cell. Biol., 30, 366-371
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 366-371
    • Tell, G.1    Wilson III, D.M.2    Lee, C.H.3
  • 11
    • 4944240061 scopus 로고    scopus 로고
    • Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endocuclease from human placenta
    • DOI 10.1093/nar/gkh846
    • Beloglazova, N. G., Kirpota, O. O., Starostin, K. V., Ishchenko, A. A., Yamkovoy, V. I., Zharkov, D. O., Douglas, K. T. and Nevinsky, G. A. (2004) Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta. Nucleic Acids Res. 32, 5134-5146 (Pubitemid 39445501)
    • (2004) Nucleic Acids Research , vol.32 , Issue.17 , pp. 5134-5146
    • Beloglazova, N.G.1    Kirpota, O.O.2    Starostin, K.V.3    Ishchenko, A.A.4    Yamkovoy, V.I.5    Zharkov, D.O.6    Douglas, K.T.7    Nevinsky, G.A.8
  • 13
    • 67651149733 scopus 로고    scopus 로고
    • Identification of apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA
    • Barnes, T., Kim, W. C., Mantha, A. K., Kim, S. E., Izumi, T., Mitra, S. and Lee, C. H. (2009) Identification of apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA. Nucleic Acids Res. 37, 3946-3958
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3946-3958
    • Barnes, T.1    Kim, W.C.2    Mantha, A.K.3    Kim, S.E.4    Izumi, T.5    Mitra, S.6    Lee, C.H.7
  • 14
    • 0030728449 scopus 로고    scopus 로고
    • The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites
    • DOI 10.1093/emboj/16.21.6548
    • Gorman, M. A., Morera, S., Rothwell, D. G., de La Fortelle, E., Mol, C. D., Tainer, J. A., Hickson, I. D. and Freemont, P. S. (1997) The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. EMBO J. 16, 6548-6558 (Pubitemid 27483279)
    • (1997) EMBO Journal , vol.16 , Issue.21 , pp. 6548-6558
    • Gorman, M.A.1    Morera, S.2    Rothwell, D.G.3    De La, F.E.4    Mol, C.D.5    Tainer, J.A.6    Hickson, I.D.7    Freemont, P.S.8
  • 15
    • 0035815108 scopus 로고    scopus 로고
    • Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: Implications for the catalytic mechanism
    • DOI 10.1006/jmbi.2001.4529
    • Beernink, P. T., Segelke, B. W., Hadi, M. Z., Erzberger, J. P., Wilson, III, D. M. and Rupp, B. (2001) Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism. J. Mol. Biol. 307, 1023-1034 (Pubitemid 33029950)
    • (2001) Journal of Molecular Biology , vol.307 , Issue.4 , pp. 1023-1034
    • Beernink, P.T.1    Segelke, B.W.2    Hadi, M.Z.3    Erzberger, J.P.4    Wilson III, D.M.5    Rupp, B.6
  • 16
    • 0032486475 scopus 로고    scopus 로고
    • Domain mapping of human apurinic/apyrimidinic endonuclease: Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain
    • DOI 10.1074/jbc.273.23.14435
    • Strauss, P. R. and Holt, C. M. (1998) Domain mapping of human apurinic/apyrimidinic endonuclease. Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain. J. Biol. Chem. 273, 14435-14441 (Pubitemid 28319164)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.23 , pp. 14435-14441
    • Strauss, P.R.1    Holt, C.M.2
  • 18
    • 0037318731 scopus 로고    scopus 로고
    • Cleaving the oxidative repair protein Ape I enhances cell death mediated by granzyme A
    • DOI 10.1038/ni885
    • Fan, Z., Beresford, P. J., Zhang, D., Xu, Z., Novina, C. D., Yoshida, A., Pommier, Y. and Lieberman, J. (2003) Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat. Immunol. 4, 145-153 (Pubitemid 36193016)
    • (2003) Nature Immunology , vol.4 , Issue.2 , pp. 145-153
    • Fan, Z.1    Beresford, P.J.2    Zhang, D.3    Xu, Z.4    Novina, C.D.5    Yoshida, A.6    Pommier, Y.7    Lieberman, J.8
  • 19
    • 64049110265 scopus 로고    scopus 로고
    • Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway
    • Busso, C. S., Iwakuma, T. and Izumi, T. (2009) Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway. Oncogene 28, 1616-1625
    • (2009) Oncogene , vol.28 , pp. 1616-1625
    • Busso, C.S.1    Iwakuma, T.2    Izumi, T.3
  • 22
    • 84862978423 scopus 로고    scopus 로고
    • Oxidized base damage and single-strand break repairin mammalian genomes: Role of disordered regions and posttranslational modifications in early enzymes
    • Hedge, M. L., Izumi, T. and Mitra, S. (2012) Oxidized base damage and single-strand break repairin mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes. Prog. Mol. Biol. Transl. Sci. 110, 123-153
    • (2012) Prog. Mol. Biol. Transl. Sci. , vol.110 , pp. 123-153
    • Hedge, M.L.1    Izumi, T.2    Mitra, S.3
  • 23
    • 78149471195 scopus 로고    scopus 로고
    • Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment
    • Tell, G., Fantini, D. and Quadrifoglio, F. (2010) Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment. Cell. Mol. Life Sci. 67, 3589-3608
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 3589-3608
    • Tell, G.1    Fantini, D.2    Quadrifoglio, F.3
  • 24
    • 34248679167 scopus 로고    scopus 로고
    • Tricine-SDS-PAGE
    • Schägger, H. (2006) Tricine-SDS-PAGE. Nat. Protoc. 1, 16-22
    • (2006) Nat. Protoc. , vol.1 , pp. 16-22
    • Schägger, H.1
  • 25
    • 0034607548 scopus 로고    scopus 로고
    • Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease
    • Nguyen, L. H., Barsky, D., Erzberger, J. P. and Wilson, III, D. M. (2000) Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease. J. Mol. Biol. 298, 447-459
    • (2000) J. Mol. Biol. , vol.298 , pp. 447-459
    • Nguyen, L.H.1    Barsky, D.2    Erzberger, J.P.3    Wilson III, D.M.4
  • 26
    • 43049167396 scopus 로고    scopus 로고
    • Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision
    • Berquist, B. R., McNeill, D. R. and Wilson, III, D. M. (2008) Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision. J. Mol. Biol. 379, 17-27
    • (2008) J. Mol. Biol. , vol.379 , pp. 17-27
    • Berquist, B.R.1    McNeill, D.R.2    Wilson III, D.M.3
  • 27
    • 0034719372 scopus 로고    scopus 로고
    • DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
    • DOI 10.1038/35000249
    • Mol, C. D., Izumi, T., Mitra, S. and Tainer, J. A. (2000) DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination. Nature 403, 451-456 (Pubitemid 30073097)
    • (2000) Nature , vol.403 , Issue.6768 , pp. 451-456
    • Mol, C.D.1    Izumi, T.2    Mitra, S.3    Talner, J.A.4
  • 28
    • 0030839750 scopus 로고    scopus 로고
    • Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites
    • DOI 10.1093/nar/25.5.933
    • Wilson, III, D. M., Takeshita, M. and Demple, B. (1997) Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites. Nucleic Acids Res. 25, 933-939 (Pubitemid 27298260)
    • (1997) Nucleic Acids Research , vol.25 , Issue.5 , pp. 933-939
    • Wilson III, D.M.1    Takeshita, M.2    Demple, B.3
  • 29
    • 0036351172 scopus 로고    scopus 로고
    • Kinetic studies of RNA-protein interactions using surface plasmon resonance
    • DOI 10.1016/S1046-2023(02)00012-9, PII S1046202302000129
    • Katsamba, P. S., Park, S. and Laird-Offringa, I. A. (2002) Kinetic studies of RNA-protein interactions using surface plasmon resonance. Methods 26, 95-104 (Pubitemid 34969571)
    • (2002) Methods , vol.26 , Issue.2 , pp. 95-104
    • Katsamba, P.S.1    Park, S.2    Laird-Offringa, I.A.3
  • 30
    • 33745616104 scopus 로고    scopus 로고
    • The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA
    • DOI 10.1261/rna.75206
    • Law, M. J., Rice, A. J., Lin, P. and Laird-Offringa, I. A. (2006) The role of RNA structure in the interaction of U1A protein with U1 hairpin II RNA. RNA 12, 1168-1178 (Pubitemid 43990542)
    • (2006) RNA , vol.12 , Issue.7 , pp. 1168-1178
    • Law, M.J.1    Rice, A.J.2    Lin, P.3    Laird-Offringa, I.A.4
  • 31
    • 0030478864 scopus 로고    scopus 로고
    • Negative regulation of the major human AP-endonuclease, a multifunctional protein
    • DOI 10.1021/bi961995u
    • Izumi, T., Henner, W. D. and Mitra, S. (1996) Negative regulation of the major human AP-endonuclease, a multifunctional protein. Biochemistry 35, 14679-14683 (Pubitemid 26423798)
    • (1996) Biochemistry , vol.35 , Issue.47 , pp. 14679-14683
    • Izumi, T.1    Henner, W.D.2    Mitra, S.3
  • 32
    • 80051670958 scopus 로고    scopus 로고
    • Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1
    • Kim, W. C., Berquist, B. R., Chohan, M., Uy, C., Wilson, III, D. M. and Lee, C. H. (2011) Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1. J. Mol. Biol. 411, 960-971
    • (2011) J. Mol. Biol. , vol.411 , pp. 960-971
    • Kim, W.C.1    Berquist, B.R.2    Chohan, M.3    Uy, C.4    Wilson III, D.M.5    Lee, C.H.6
  • 33
    • 82655179905 scopus 로고    scopus 로고
    • Intrinsically disordered regions as affinity tuners in protein-DNA interactions
    • Vuzman, D. and Levy, Y. (2012) Intrinsically disordered regions as affinity tuners in protein-DNA interactions. Mol. Biosyst. 8, 47-57
    • (2012) Mol. Biosyst. , vol.8 , pp. 47-57
    • Vuzman, D.1    Levy, Y.2
  • 34
    • 0032515143 scopus 로고    scopus 로고
    • Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product
    • DOI 10.1074/jbc.273.46.30352
    • Masuda, Y., Bennett, R. A. O. and Demple, B. (1998) Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product. J. Biol. Chem. 273, 30352-30359 (Pubitemid 28545505)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.46 , pp. 30352-30359
    • Masuda, Y.1    Bennett, R.A.O.2    Demple, B.3
  • 35
    • 0023657761 scopus 로고
    • Identification and characterization of a hexameric form of nucleolar phosphoprotein B23
    • Yung, B. Y. and Chan, P. K. (1987) Identification and characterization of a hexameric form of nucleolar phosphoprotein B23. Biochim. Biophys. Acta 925, 74-82
    • (1987) Biochim. Biophys. Acta , vol.925 , pp. 74-82
    • Yung, B.Y.1    Chan, P.K.2
  • 37
    • 20444490757 scopus 로고    scopus 로고
    • Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
    • DOI 10.1093/nar/gki641
    • Jackson, E. B., Theriot, C. A., Chattopadhyay, R., Mitra, S. and Izumi, T. (2005) Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1). Nucleic Acids Res. 33, 3303-3312 (Pubitemid 41194474)
    • (2005) Nucleic Acids Research , vol.33 , Issue.10 , pp. 3303-3312
    • Jackson, E.B.1    Theriot, C.A.2    Chattopadhyay, R.3    Mitra, S.4    Izumi, T.5
  • 40
    • 40149091820 scopus 로고    scopus 로고
    • Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity
    • Guo, Y., Chen, J., Zhao, T. and Fan, Z. (2008) Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity. Mol. Immunol. 45, 2225-2235
    • (2008) Mol. Immunol. , vol.45 , pp. 2225-2235
    • Guo, Y.1    Chen, J.2    Zhao, T.3    Fan, Z.4
  • 41
    • 0035890069 scopus 로고    scopus 로고
    • XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
    • DOI 10.1093/emboj/20.22.6530
    • Vidal, A. E., Boiteux, S., Hickson, I. D. and Radicella, J. P. (2001) XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions. EMBO J. 20, 6530-6539 (Pubitemid 33078725)
    • (2001) EMBO Journal , vol.20 , Issue.22 , pp. 6530-6539
    • Vidal, A.E.1    Boiteux, S.2    Hickson, I.D.3    Radicella, J.P.4
  • 42
    • 77951895418 scopus 로고    scopus 로고
    • Probing conformational changes in Ape1 during the progression of base excision repair
    • Yu, E., Gaucher, S. P. and Hadi, M. Z. (2010) Probing conformational changes in Ape1 during the progression of base excision repair. Biochemistry 49, 3786-3796
    • (2010) Biochemistry , vol.49 , pp. 3786-3796
    • Yu, E.1    Gaucher, S.P.2    Hadi, M.Z.3
  • 43
    • 34547627642 scopus 로고    scopus 로고
    • Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates
    • DOI 10.1093/nar/gkm404
    • Wong, H. K., Muftuoglu, M., Beck, G., Imam, S. Z., Bohr, V. A. and Wilson, III, D. M. (2007) Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates. Nucleic Acids Res. 35, 4103-4113 (Pubitemid 47244631)
    • (2007) Nucleic Acids Research , vol.35 , Issue.12 , pp. 4103-4113
    • Wong, H.-K.1    Muftuoglu, M.2    Beck, G.3    Imam, S.Z.4    Bohr, V.A.5    Wilson III, D.M.6
  • 44
    • 49049087691 scopus 로고    scopus 로고
    • Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
    • Georgiadis, M. M., Luo, M., Gaur, R. K., Delaplane, S., Li, X. and Kelley, M. R. (2008) Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease. Mutat. Res. 643, 54-63
    • (2008) Mutat. Res. , vol.643 , pp. 54-63
    • Georgiadis, M.M.1    Luo, M.2    Gaur, R.K.3    Delaplane, S.4    Li, X.5    Kelley, M.R.6


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