LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection

Journal of Experimental Medicine

Volumn 214, Issue 10, 2017, Pages 3051-3066

  Liu, Weiwei ^a   Liu, Xia'nan ^a   Li, Yu ^a   Zhao, Junjie ^b   Liu, Zhenshan ^a   Hu, Zhuqin ^a   Wang, Ying ^a   Yao, Yufeng ^a   Miller, Aaron W ^b   Su, Bing ^a   Cookson, Mark R ^c   Li, Xiaoxia ^b,d   Kang, Zizhen ^a,b,d  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUCINE RICH REPEAT KINASE 2; PROTEIN KINASE; PROTEIN NLRC4; SERINE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE; LRRK2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE SILENCING; HEK293T CELL LINE; HOST RESISTANCE; HUMAN; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; ANIMAL; ANIMAL SALMONELLOSIS; C57BL MOUSE; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM-BINDING PROTEINS; CASPASE 1; INFLAMMASOMES; INTERLEUKIN-1BETA; LEUCINE-RICH REPEAT SERINE-THREONINE PROTEIN KINASE-2; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM;

EID: 85030645713     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20170014     Document Type: Article

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