Flagellin-induced NLCR4 phosphorylation primes the inflammasome for activation by NAIP5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages 1541-1546

  Matusiak, Magdalena ^a,b   Van Opdenbosch, Nina ^a,b   Vande Walle, Lieselotte ^a,b   Sirard, Jean Claude ^c   Kanneganti, Thirumala Devi ^d   Lamkanfi, Mohamed ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c INSTITUT PASTEUR DE LILLE   (France)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Caspase 1; Flagellin; Inflammasome; NLRC4; Salmonella

Indexed keywords

FLAGELLIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MEMBRANE PROTEIN; NAIP5 PROTEIN; NLRC4 PROTEIN; SERINE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE; NAIP5 PROTEIN, MOUSE; NEURONAL APOPTOSIS INHIBITORY PROTEIN; PRIMER DNA;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HELICOBACTER PYLORI; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; YERSINIA ENTEROCOLITICA; ANIMAL; CHEMISTRY; ENZYME ACTIVATION; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM;

HELICOBACTER PYLORI; SALMONELLA; SALMONELLA TYPHIMURIUM; YERSINIA ENTEROCOLITICA;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CALCIUM-BINDING PROTEINS; CASPASE 1; DNA PRIMERS; ENZYME ACTIVATION; FLAGELLIN; INFLAMMASOMES; MICE; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM; SERINE; YERSINIA ENTEROCOLITICA;

EID: 84922311780     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417945112     Document Type: Article

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