메뉴 건너뛰기




Volumn 242, Issue , 2018, Pages 75-82

Peptides derived from in vitro gastrointestinal digestion of germinated soybean proteins inhibit human colon cancer cells proliferation and inflammation

Author keywords

Anti inflammatory; Antiproliferative; Digestion; Germination; Peptides; Soybean

Indexed keywords

AMINO ACIDS; CELL PROLIFERATION; CELLS; CULTIVATION; PEPTIDES; SLUDGE DIGESTION;

EID: 85029145175     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2017.09.035     Document Type: Article
Times cited : (172)

References (39)
  • 2
    • 45349096041 scopus 로고    scopus 로고
    • Cancer facts and figures 2016
    • American Cancer Association, Cancer facts and figures 2016. 2016 http://old.cancer.org/acs/groups/content/@research/documents/document/acspc-047079.pdf.
    • (2016)
    • American Cancer Association1
  • 5
    • 77957604071 scopus 로고    scopus 로고
    • The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells
    • De Mejia, E.G., Dia, V.P., The role of nutraceutical proteins and peptides in apoptosis, angiogenesis, and metastasis of cancer cells. Cancer and Metastasis Reviews 29:3 (2010), 511–528.
    • (2010) Cancer and Metastasis Reviews , vol.29 , Issue.3 , pp. 511-528
    • De Mejia, E.G.1    Dia, V.P.2
  • 6
    • 84938749232 scopus 로고    scopus 로고
    • Germination of Phaseolus vulgaris and alcalase hydrolysis of its proteins produced bioactive peptides capable of improving markers related to type-2 diabetes in vitro
    • De Souza Rocha, T., Hernandez, L.M.R., Mojica, L., Johnson, M.H., Chang, Y.K., de Mejia, E.G., Germination of Phaseolus vulgaris and alcalase hydrolysis of its proteins produced bioactive peptides capable of improving markers related to type-2 diabetes in vitro. Food Research International 76:P1 (2015), 150–159.
    • (2015) Food Research International , vol.76 , Issue.P1 , pp. 150-159
    • De Souza Rocha, T.1    Hernandez, L.M.R.2    Mojica, L.3    Johnson, M.H.4    Chang, Y.K.5    de Mejia, E.G.6
  • 7
    • 84890955013 scopus 로고    scopus 로고
    • Peptides in pepsin–pancreatin hydrolysates from commercially available soy products that inhibit lipopolysaccharide-induced inflammation in macrophages
    • Dia, V.P., Bringe, N.A., de Mejia, E.G., Peptides in pepsin–pancreatin hydrolysates from commercially available soy products that inhibit lipopolysaccharide-induced inflammation in macrophages. Food Chemistry 152:1 (2014), 423–431.
    • (2014) Food Chemistry , vol.152 , Issue.1 , pp. 423-431
    • Dia, V.P.1    Bringe, N.A.2    de Mejia, E.G.3
  • 8
    • 79953319182 scopus 로고    scopus 로고
    • Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells
    • Dia, V.P., de Mejia, E.G., Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells. Molecular Nutrition & Food Research 55:4 (2011), 623–634.
    • (2011) Molecular Nutrition & Food Research , vol.55 , Issue.4 , pp. 623-634
    • Dia, V.P.1    de Mejia, E.G.2
  • 9
    • 84865140171 scopus 로고    scopus 로고
    • Bowman-Birk and Kunitz protease inhibitors among antinutrients and bioactives modified by germination and hydrolysis in Brazilian soybean cultivar BRS 133
    • Dia, V.P., Gomez, T., Vernaza, G., Berhow, M., Chang, Y.K., de Mejia, E.G., Bowman-Birk and Kunitz protease inhibitors among antinutrients and bioactives modified by germination and hydrolysis in Brazilian soybean cultivar BRS 133. Journal of Agricultural and Food Chemistry 60:32 (2012), 7886–7894.
    • (2012) Journal of Agricultural and Food Chemistry , vol.60 , Issue.32 , pp. 7886-7894
    • Dia, V.P.1    Gomez, T.2    Vernaza, G.3    Berhow, M.4    Chang, Y.K.5    de Mejia, E.G.6
  • 10
    • 84987984841 scopus 로고    scopus 로고
    • BG-4 a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells
    • Dia, V.P., Krishnan, H.B., BG-4 a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells. Scientific Reports, 6, 2016, 33532.
    • (2016) Scientific Reports , vol.6 , pp. 33532
    • Dia, V.P.1    Krishnan, H.B.2
  • 11
    • 84978069670 scopus 로고    scopus 로고
    • Evaluation of the antioxidant and antiproliferative effects of three peptide fractions of germinated soybeans on breast and cervical cancer cell lines
    • González-Montoya, M., Ramón-Gallegos, E., Robles-Ramírez, M. del C., Mora-Escobedo, R., Evaluation of the antioxidant and antiproliferative effects of three peptide fractions of germinated soybeans on breast and cervical cancer cell lines. Plant Foods for Human Nutrition 71:4 (2016), 368–374.
    • (2016) Plant Foods for Human Nutrition , vol.71 , Issue.4 , pp. 368-374
    • González-Montoya, M.1    Ramón-Gallegos, E.2    Robles-Ramírez, M.D.C.3    Mora-Escobedo, R.4
  • 12
    • 13244277961 scopus 로고    scopus 로고
    • Preparation of antioxidant enzymatic hydrolysates from alpha-lactalbumin and beta-lactoglobulin. Identification of active peptides by HPLC-MS/MS
    • Hernández-Ledesma, B., Dávalos, A., Bartolomé, B., Amigo, L., Preparation of antioxidant enzymatic hydrolysates from alpha-lactalbumin and beta-lactoglobulin. Identification of active peptides by HPLC-MS/MS. Journal of Agricultural and Food Chemistry 53:3 (2005), 588–593.
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , Issue.3 , pp. 588-593
    • Hernández-Ledesma, B.1    Dávalos, A.2    Bartolomé, B.3    Amigo, L.4
  • 13
    • 58149505705 scopus 로고    scopus 로고
    • Lunasin, a novel seed peptide for cancer prevention
    • Hernández-Ledesma, B., Hsieh, C.C., de Lumen, B.O., Lunasin, a novel seed peptide for cancer prevention. Peptides 30:2 (2009), 426–430.
    • (2009) Peptides , vol.30 , Issue.2 , pp. 426-430
    • Hernández-Ledesma, B.1    Hsieh, C.C.2    de Lumen, B.O.3
  • 14
  • 15
    • 84956993931 scopus 로고    scopus 로고
    • Anti-inflammatory action of high molecular weight Mytilus edulis hydrolysates fraction in LPS-induced RAW264.7 macrophage via NF-κB and MAPK pathways
    • Kim, Y.S., Ahn, C.B., Je, J.Y., Anti-inflammatory action of high molecular weight Mytilus edulis hydrolysates fraction in LPS-induced RAW264.7 macrophage via NF-κB and MAPK pathways. Food Chemistry 202:1 (2016), 9–14.
    • (2016) Food Chemistry , vol.202 , Issue.1 , pp. 9-14
    • Kim, Y.S.1    Ahn, C.B.2    Je, J.Y.3
  • 16
    • 84872383575 scopus 로고    scopus 로고
    • Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages
    • Kim, K.N., Ko, Y.J., Kang, M.C., Yang, H.M., Roh, S.W., Oda, T., Kim, D., Anti-inflammatory effects of trans-1,3-diphenyl-2,3-epoxypropane-1-one mediated by suppression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages. Food and Chemical Toxicology 53:1 (2013), 371–375.
    • (2013) Food and Chemical Toxicology , vol.53 , Issue.1 , pp. 371-375
    • Kim, K.N.1    Ko, Y.J.2    Kang, M.C.3    Yang, H.M.4    Roh, S.W.5    Oda, T.6    Kim, D.7
  • 17
    • 84896140078 scopus 로고    scopus 로고
    • Peptides in common bean fractions inhibit human colorectal cancer cells
    • Luna-Vital, D.A., de Mejia, E.G., Dia, V.P., Loarca-Piña, G., Peptides in common bean fractions inhibit human colorectal cancer cells. Food Chemistry 157:1 (2014), 347–355.
    • (2014) Food Chemistry , vol.157 , Issue.1 , pp. 347-355
    • Luna-Vital, D.A.1    de Mejia, E.G.2    Dia, V.P.3    Loarca-Piña, G.4
  • 18
    • 84959161050 scopus 로고    scopus 로고
    • Selective mechanism of action of dietary peptides from common bean on HCT116 human colorectal cancer cells through loss of mitochondrial membrane potential and DNA damage
    • Luna-Vital, D.A., de Mejia, E.G., Loarca-Piña, G., Selective mechanism of action of dietary peptides from common bean on HCT116 human colorectal cancer cells through loss of mitochondrial membrane potential and DNA damage. Journal of Functional Foods 23:1 (2016), 24–39.
    • (2016) Journal of Functional Foods , vol.23 , Issue.1 , pp. 24-39
    • Luna-Vital, D.A.1    de Mejia, E.G.2    Loarca-Piña, G.3
  • 19
    • 84983474704 scopus 로고    scopus 로고
    • Effect of germination on antioxidant and ACE inhibitory activities of legumes
    • Mamilla, R.K., Mishra, V.K., Effect of germination on antioxidant and ACE inhibitory activities of legumes. LWT – Food Science and Technology 75:1 (2017), 51–58.
    • (2017) LWT – Food Science and Technology , vol.75 , Issue.1 , pp. 51-58
    • Mamilla, R.K.1    Mishra, V.K.2
  • 21
    • 69149094546 scopus 로고    scopus 로고
    • Protein hydrolysates from β-Conglycinin enriched soybean genotypes inhibit lipid accumulation and inflammation in vitro
    • Martínez-Villaluenga, C., Dia, V.P., Berhow, M., Bringe, N.A., de Mejia, E.G., Protein hydrolysates from β-Conglycinin enriched soybean genotypes inhibit lipid accumulation and inflammation in vitro. Molecular Nutrition and Food Research 53:8 (2009), 1007–1018.
    • (2009) Molecular Nutrition and Food Research , vol.53 , Issue.8 , pp. 1007-1018
    • Martínez-Villaluenga, C.1    Dia, V.P.2    Berhow, M.3    Bringe, N.A.4    de Mejia, E.G.5
  • 22
    • 84945285813 scopus 로고    scopus 로고
    • Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells
    • Montales, M.T.E., Simmen, R.C.M., Ferreira, E.S., Neves, V.A., Simmen, F.A., Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells. Genes and Nutrition 10:6 (2015), 1–14.
    • (2015) Genes and Nutrition , vol.10 , Issue.6 , pp. 1-14
    • Montales, M.T.E.1    Simmen, R.C.M.2    Ferreira, E.S.3    Neves, V.A.4    Simmen, F.A.5
  • 23
  • 24
    • 84872765089 scopus 로고    scopus 로고
    • Britanin suppresses LPS-induced nitric oxide, PGE2 and cytokine production via NF- κβB and MAPK inactivation in RAW 264.7 cells
    • Park, H.H., Kim, M.J., Li, Y., Park, Y.N., Lee, J., Lee, Y.J., Lee, E., Britanin suppresses LPS-induced nitric oxide, PGE2 and cytokine production via NF- κβB and MAPK inactivation in RAW 264.7 cells. International Immunopharmacology 15:2 (2013), 296–302.
    • (2013) International Immunopharmacology , vol.15 , Issue.2 , pp. 296-302
    • Park, H.H.1    Kim, M.J.2    Li, Y.3    Park, Y.N.4    Lee, J.5    Lee, Y.J.6    Lee, E.7
  • 25
    • 70350568646 scopus 로고    scopus 로고
    • Optimisation of germination time and temperature on the concentration of bioactive compounds in Brazilian soybean cultivar BRS 133 using response surface methodology
    • Paucar-Menacho, L.M., Berhow, M.A., Mandarino, J.M.G., de Mejia, E.G., Chang, Y.K., Optimisation of germination time and temperature on the concentration of bioactive compounds in Brazilian soybean cultivar BRS 133 using response surface methodology. Food Chemistry 119:2 (2010), 636–642.
    • (2010) Food Chemistry , vol.119 , Issue.2 , pp. 636-642
    • Paucar-Menacho, L.M.1    Berhow, M.A.2    Mandarino, J.M.G.3    de Mejia, E.G.4    Chang, Y.K.5
  • 26
    • 8744284312 scopus 로고    scopus 로고
    • Prevention of colorectal cancer through the use of COX-2 selective inhibitors
    • Peek, R.M., Prevention of colorectal cancer through the use of COX-2 selective inhibitors. Cancer Chemotherapy and Pharmacology 54:1 (2004), 50–56, 10.1007/s00280-004-0887-x.
    • (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.1 , pp. 50-56
    • Peek, R.M.1
  • 27
    • 84860624979 scopus 로고    scopus 로고
    • A peptide fraction from germinated soybean protein down-regulates PTTG1 and TOP2A mRNA expression, inducing apoptosis in cervical cancer cells
    • Robles-Ramírez, M.C., Ramón-Gallegos, E., Mora-Escobedo, R., Torres-Torres, N., A peptide fraction from germinated soybean protein down-regulates PTTG1 and TOP2A mRNA expression, inducing apoptosis in cervical cancer cells. Journal of Experimental Therapeutics & Oncology 9:4 (2012), 255–263.
    • (2012) Journal of Experimental Therapeutics & Oncology , vol.9 , Issue.4 , pp. 255-263
    • Robles-Ramírez, M.C.1    Ramón-Gallegos, E.2    Mora-Escobedo, R.3    Torres-Torres, N.4
  • 28
    • 84873690775 scopus 로고    scopus 로고
    • Effect of germinated soy protein on the growth of HeLa cervical cancer cells in female athymic mice
    • Robles-Ramírez, M.C., Ramón-Gallegos, E., Reyes-Duarte, F.J., Mora-Escobedo, R., Effect of germinated soy protein on the growth of HeLa cervical cancer cells in female athymic mice. Nutrition and Cancer 64:8 (2012), 1261–1268.
    • (2012) Nutrition and Cancer , vol.64 , Issue.8 , pp. 1261-1268
    • Robles-Ramírez, M.C.1    Ramón-Gallegos, E.2    Reyes-Duarte, F.J.3    Mora-Escobedo, R.4
  • 32
    • 84931846533 scopus 로고    scopus 로고
    • Proteases and their receptors as mediators of inflammation-associated colon cancer
    • Trusevych, E.H., MacNaughton, W.K., Proteases and their receptors as mediators of inflammation-associated colon cancer. Current Pharmaceutical Design 21:21 (2015), 2983–2992.
    • (2015) Current Pharmaceutical Design , vol.21 , Issue.21 , pp. 2983-2992
    • Trusevych, E.H.1    MacNaughton, W.K.2
  • 34
    • 84877285401 scopus 로고    scopus 로고
    • Almond protein hydrolysate fraction modulates the expression of proinflammatory cytokines and enzymes in activated macrophages
    • Udenigwe, C.C., Je, J.-Y., Cho, Y.-S., Yada, R.Y., Almond protein hydrolysate fraction modulates the expression of proinflammatory cytokines and enzymes in activated macrophages. Food and Function 4:5 (2013), 777–783.
    • (2013) Food and Function , vol.4 , Issue.5 , pp. 777-783
    • Udenigwe, C.C.1    Je, J.-Y.2    Cho, Y.-S.3    Yada, R.Y.4
  • 35
    • 84861574417 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory properties of germinated and hydrolysed Brazilian soybean flours
    • Vernaza, M.G., Dia, V.P., de Mejia, E.G., Chang, Y.K., Antioxidant and antiinflammatory properties of germinated and hydrolysed Brazilian soybean flours. Food Chemistry 134:4 (2012), 2217–2225.
    • (2012) Food Chemistry , vol.134 , Issue.4 , pp. 2217-2225
    • Vernaza, M.G.1    Dia, V.P.2    de Mejia, E.G.3    Chang, Y.K.4
  • 36
    • 85009435137 scopus 로고    scopus 로고
    • Improvement of soybean products through the response mechanism analysis using proteomic technique
    • Wang, X., Komatsu, S., Improvement of soybean products through the response mechanism analysis using proteomic technique. Advances in Food and Nutrition Research 82:1 (2017), 117–148.
    • (2017) Advances in Food and Nutrition Research , vol.82 , Issue.1 , pp. 117-148
    • Wang, X.1    Komatsu, S.2
  • 37
    • 0036850529 scopus 로고    scopus 로고
    • Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells
    • Yang, W., Dunlap, J.R., Andrews, R.B., Wetzel, R., Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells. Human Molecular Genetics 11:23 (2002), 2905–2917.
    • (2002) Human Molecular Genetics , vol.11 , Issue.23 , pp. 2905-2917
    • Yang, W.1    Dunlap, J.R.2    Andrews, R.B.3    Wetzel, R.4
  • 39
    • 84924229728 scopus 로고    scopus 로고
    • Dietary legume consumption reduces risk of colorectal cancer: Evidence from a meta-analysis of cohort studies
    • Zhu, B., Sun, Y., Qi, L., Zhong, R., Miao, X., Dietary legume consumption reduces risk of colorectal cancer: Evidence from a meta-analysis of cohort studies. Scientific Reports 5:1 (2015), 87–97.
    • (2015) Scientific Reports , vol.5 , Issue.1 , pp. 87-97
    • Zhu, B.1    Sun, Y.2    Qi, L.3    Zhong, R.4    Miao, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.