Acacia nilotica leaf improves insulin resistance and hyperglycemia associated acute hepatic injury and nephrotoxicity by improving systemic antioxidant status in diabetic mice

Journal of Ethnopharmacology

Volumn 210, Issue , 2018, Pages 275-286

  Saha, Manas Ranjan ^a   Dey, Priyankar ^a,b   Sarkar, Indrani ^a   De Sarker, Dilip ^c   Haldar, Biswajit ^d   Chaudhuri, Tapas Kumar ^a   Sen, Arnab ^a  

^a UNIVERSITY OF NORTH BENGAL   (India)

^b OHIO STATE UNIVERSITY   (United States)

^c RAIGANJ UNIVERSITY   (India)

^d NORTH BENGAL MEDICAL COLLEGE   (India)

Author keywords

Acacia nilotica; Antidiabetic; Antioxidant; GC MS; Insulin resistance; Nrf2

Indexed keywords

ACACIA NILOTICA EXTRACT; ACID PHOSPHATASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; CATECHOL; CREATININE; GALLIC ACID; GLIBENCLAMIDE; GLUCOSE; GLYCOGEN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; MALONALDEHYDE; NITROGEN; PEROXIDASE; PHYTOL; PYROGALLOL; QUERCETIN; SITOSTEROL; SQUALENE; STIGMASTEROL; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TOCOPHEROL; TRANSCRIPTION FACTOR NRF2; TRIACYLGLYCEROL; UNINDEXED DRUG; UREA; URIC ACID; ANTIDIABETIC AGENT; ANTIOXIDANT; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; PLANT EXTRACT;

ALLOXAN-INDUCED DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIABETES CONTROL; DRUG MEGADOSE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; HISTOPATHOLOGY; HYPERGLYCEMIA; HYPERLIPIDEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; KIDNEY; LIPID PEROXIDATION; LIVER; LIVER INJURY; LOW DRUG DOSE; MALE; METABOLIC PARAMETERS; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOUSE; NEPHROTOXICITY; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; PLANT LEAF; SKELETAL MUSCLE; UREA NITROGEN BLOOD LEVEL; VACHELLIA NILOTICA; ACACIA; ANIMAL; CHEMISTRY; COMPLICATION; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; MASS FRAGMENTOGRAPHY; METABOLISM; ORAL DRUG ADMINISTRATION; TRADITIONAL MEDICINE;

ACACIA; ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCATED HEMOGLOBIN A; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MALE; MEDICINE, TRADITIONAL; MICE; MOLECULAR DOCKING SIMULATION; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES;

EID: 85028862943     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2017.08.036     Document Type: Article

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