메뉴 건너뛰기




Volumn 23, Issue , 2016, Pages 315-328

Immunomodulatory activities and phytochemical characterisation of the methanolic extract of Dioscorea alata aerial tuber

Author keywords

Anti inflammatory; Cytokine; Dioscorea alata; GC MS; HPLC; Macrophage

Indexed keywords


EID: 84960082492     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2016.02.044     Document Type: Article
Times cited : (17)

References (49)
  • 1
    • 0345137458 scopus 로고
    • Genetic improvement of vegetable crops: Yam (Dioscorea spp
    • Pergamon Press, New York, M. Kasloo (Ed.)
    • Akoruda M.O. Genetic improvement of vegetable crops: Yam (Dioscorea spp. Genetic improvement of vegetable crops 1984, Pergamon Press, New York. M. Kasloo (Ed.).
    • (1984) Genetic improvement of vegetable crops
    • Akoruda, M.O.1
  • 3
    • 0035865329 scopus 로고    scopus 로고
    • Il-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production
    • Berg D.J., Zhang J., Lauricella D.M., Moore S.A. Il-10 is a central regulator of cyclooxygenase-2 expression and prostaglandin production. Journal of Immunology 2001, 166:2674-2680.
    • (2001) Journal of Immunology , vol.166 , pp. 2674-2680
    • Berg, D.J.1    Zhang, J.2    Lauricella, D.M.3    Moore, S.A.4
  • 6
    • 13244281580 scopus 로고    scopus 로고
    • Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide
    • Changhua L., Jindong Y., Defa L., Lidan Z., Shiyan Q., Jianjun X. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide. The Journal of Nutrition 2005, 135:239-244.
    • (2005) The Journal of Nutrition , vol.135 , pp. 239-244
    • Changhua, L.1    Jindong, Y.2    Defa, L.3    Lidan, Z.4    Shiyan, Q.5    Jianjun, X.6
  • 7
    • 0035214067 scopus 로고    scopus 로고
    • The efficacy of a commercial beta-glucan preparation, EcoActiva, on stimulating respiratory burst activity of head-kidney macrophages from pink snapper (Pagrus auratus), Sparidae
    • Cook M.T., Hayball P.J., Hutchinson W., Nowak B., Hayball J.D. The efficacy of a commercial beta-glucan preparation, EcoActiva, on stimulating respiratory burst activity of head-kidney macrophages from pink snapper (Pagrus auratus), Sparidae. Fish and Shellfish Immunology 2001, 11:661-672.
    • (2001) Fish and Shellfish Immunology , vol.11 , pp. 661-672
    • Cook, M.T.1    Hayball, P.J.2    Hutchinson, W.3    Nowak, B.4    Hayball, J.D.5
  • 8
    • 84875417400 scopus 로고    scopus 로고
    • Study of antioxidant and reactive oxygen species scavenging activity of the edible tuber of "greater yam" (Dioscorea alata l.) from north-east India
    • Das A., Chaudhuri D., Mandal N., Chatterjee A. Study of antioxidant and reactive oxygen species scavenging activity of the edible tuber of "greater yam" (Dioscorea alata l.) from north-east India. Asian Journal of Pharmaceutical and Clinical Research: AJPCR 2012, 5:74-84.
    • (2012) Asian Journal of Pharmaceutical and Clinical Research: AJPCR , vol.5 , pp. 74-84
    • Das, A.1    Chaudhuri, D.2    Mandal, N.3    Chatterjee, A.4
  • 9
    • 85068981199 scopus 로고    scopus 로고
    • In vitro modulation of TH1 and TH2 cytokine expression in mitogen induced splenic T-lymphocytes by the edible tubers of Dioscorea alata
    • Dey P., Chaudhuri T.K. In vitro modulation of TH1 and TH2 cytokine expression in mitogen induced splenic T-lymphocytes by the edible tubers of Dioscorea alata. Food Science and Human Wellness 2014, 3:1-8.
    • (2014) Food Science and Human Wellness , vol.3 , pp. 1-8
    • Dey, P.1    Chaudhuri, T.K.2
  • 10
    • 84927669947 scopus 로고    scopus 로고
    • Chemical characterization and assessment of antioxidant potentiality of Streptocaulon sylvestre Wight, an endangered plant of sub-Himalayan plains of West Bengal and Sikkim
    • Dey P., Ray S., Sarkar M.P., Chaudhuri T.K. Chemical characterization and assessment of antioxidant potentiality of Streptocaulon sylvestre Wight, an endangered plant of sub-Himalayan plains of West Bengal and Sikkim. BMC Complementary and Alternative Medicine 2015, 15:107.
    • (2015) BMC Complementary and Alternative Medicine , vol.15 , pp. 107
    • Dey, P.1    Ray, S.2    Sarkar, M.P.3    Chaudhuri, T.K.4
  • 11
    • 84979564619 scopus 로고    scopus 로고
    • Stimulation of murine immune response by the tubers of Dioscorea alata L. of north-eastern region of India
    • Dey P., Roy S., Chaudhuri T.K. Stimulation of murine immune response by the tubers of Dioscorea alata L. of north-eastern region of India. Proceedings of the Zoological Society 2013, 67:140-148.
    • (2013) Proceedings of the Zoological Society , vol.67 , pp. 140-148
    • Dey, P.1    Roy, S.2    Chaudhuri, T.K.3
  • 16
    • 0031206258 scopus 로고    scopus 로고
    • Effect of sodium alginate on the non-specific defense system of the common carp (Cyprinus carpio L.)
    • Fujiki K., Yano T. Effect of sodium alginate on the non-specific defense system of the common carp (Cyprinus carpio L.). Fish and Shellfish Immunology 1997, 7:417-427.
    • (1997) Fish and Shellfish Immunology , vol.7 , pp. 417-427
    • Fujiki, K.1    Yano, T.2
  • 19
    • 0032213375 scopus 로고    scopus 로고
    • Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
    • Hampton M.B., Kettle A.J., Winterbourn C.C. Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing. Blood 1998, 91:3007-3017.
    • (1998) Blood , vol.91 , pp. 3007-3017
    • Hampton, M.B.1    Kettle, A.J.2    Winterbourn, C.C.3
  • 20
    • 0031722075 scopus 로고    scopus 로고
    • Anti-inflammatory activity of myricetin-3-O-beta-D-glucuronide and related compounds
    • Hiermann A., Schramm H.W., Laufer S. Anti-inflammatory activity of myricetin-3-O-beta-D-glucuronide and related compounds. Inflammation Research 1998, 47:421-427.
    • (1998) Inflammation Research , vol.47 , pp. 421-427
    • Hiermann, A.1    Schramm, H.W.2    Laufer, S.3
  • 22
    • 84960160048 scopus 로고    scopus 로고
    • Accessed 22.07.15
    • IITA (International Institute of Tropical Agriculture) Research to Nourish Africa Accessed 22.07.15. http://www.iita.org/yam.
    • Research to Nourish Africa
  • 23
    • 85026949463 scopus 로고    scopus 로고
    • The tuber extract and flour of Dioscorea alata normalize the blood lipid profile of rabbits treated with high cholesterol diets
    • Imanningsih N., Muchtadi D., Palupi N.S., Wresdiyati T., Komari The tuber extract and flour of Dioscorea alata normalize the blood lipid profile of rabbits treated with high cholesterol diets. Health Science Journal of Indonesia 2014, 1:23-29.
    • (2014) Health Science Journal of Indonesia , vol.1 , pp. 23-29
    • Imanningsih, N.1    Muchtadi, D.2    Palupi, N.S.3    Wresdiyati, T.K.4
  • 25
    • 58249129942 scopus 로고    scopus 로고
    • MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin
    • Kim J.E., Kwon J.Y., Lee D.E., Kang N.J., Heo Y.S., Lee K.W., Lee H.J. MKK4 is a novel target for the inhibition of tumor necrosis factor-alpha-induced vascular endothelial growth factor expression by myricetin. Biochemical Pharmacology 2009, 77:412-421.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 412-421
    • Kim, J.E.1    Kwon, J.Y.2    Lee, D.E.3    Kang, N.J.4    Heo, Y.S.5    Lee, K.W.6    Lee, H.J.7
  • 26
  • 29
    • 67149099539 scopus 로고    scopus 로고
    • Yam storage protein dioscorins from Dioscorea alata and Dioscorea japonica exhibit distinct immunomodulatory activities in mice
    • Lin P.L., Lin K.W., Weng C.F., Lin K.C. Yam storage protein dioscorins from Dioscorea alata and Dioscorea japonica exhibit distinct immunomodulatory activities in mice. Journal of Agricultural and Food Chemistry 2009, 57:4606-4613.
    • (2009) Journal of Agricultural and Food Chemistry , vol.57 , pp. 4606-4613
    • Lin, P.L.1    Lin, K.W.2    Weng, C.F.3    Lin, K.C.4
  • 30
    • 84869077659 scopus 로고    scopus 로고
    • Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating Smad- and epithelial-mesenchymal transition signaling pathways
    • Liu S.F., Chang S.Y., Lee T.C., Chuang L.Y., Guh J.Y., Hung C.Y., Hung T.J., Hung Y.J., Chen P.Y., Hsieh P.F. Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating Smad- and epithelial-mesenchymal transition signaling pathways. PLoS ONE 2012, 7:e47482.
    • (2012) PLoS ONE , vol.7 , pp. e47482
    • Liu, S.F.1    Chang, S.Y.2    Lee, T.C.3    Chuang, L.Y.4    Guh, J.Y.5    Hung, C.Y.6    Hung, T.J.7    Hung, Y.J.8    Chen, P.Y.9    Hsieh, P.F.10
  • 33
    • 0027512562 scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55
    • Mackay F., Loetscher H., Stueber D., Gehr G., Lesslauer W. Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55. The Journal of Experimental Medicine 1993, 177:1277-1286.
    • (1993) The Journal of Experimental Medicine , vol.177 , pp. 1277-1286
    • Mackay, F.1    Loetscher, H.2    Stueber, D.3    Gehr, G.4    Lesslauer, W.5
  • 34
    • 80053241976 scopus 로고    scopus 로고
    • Antidiabetic activity of ethanolic extract of tubers of Dioscorea alata in alloxan induced diabetic rats
    • Maithili V., Dhanabal S.P., Mahendran S., Vadivelan R. Antidiabetic activity of ethanolic extract of tubers of Dioscorea alata in alloxan induced diabetic rats. Indian Journal of Pharmacology 2011, 43:455-459.
    • (2011) Indian Journal of Pharmacology , vol.43 , pp. 455-459
    • Maithili, V.1    Dhanabal, S.P.2    Mahendran, S.3    Vadivelan, R.4
  • 36
    • 84991101838 scopus 로고    scopus 로고
    • OECD guidelines for the testing of chemicals
    • PDF
    • OECD iLibrary OECD guidelines for the testing of chemicals. Section 4: Health effects 2002, PDF. 10.1787/9789264071001-en.
    • (2002) Section 4: Health effects
  • 37
    • 85026951678 scopus 로고    scopus 로고
    • The cooling effect on proinflammatory cytokines interferon-gamma, tumor necrosis factor-alpha, and nitric oxide in patients with multiple sclerosis
    • Poyraz T., Idiman E., Uysal S., Iyilikci L., Ozakbaş S., Coskuner-Poyraz E., Idiman F. The cooling effect on proinflammatory cytokines interferon-gamma, tumor necrosis factor-alpha, and nitric oxide in patients with multiple sclerosis. ISRN Neurology 2013, 16. 964572.
    • (2013) ISRN Neurology , vol.16
    • Poyraz, T.1    Idiman, E.2    Uysal, S.3    Iyilikci, L.4    Ozakbaş, S.5    Coskuner-Poyraz, E.6    Idiman, F.7
  • 38
    • 84872897187 scopus 로고    scopus 로고
    • Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats
    • Pragasam S.J., Venkatesan V., Rasool M. Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. Inflammation 2013, 36:169-176.
    • (2013) Inflammation , vol.36 , pp. 169-176
    • Pragasam, S.J.1    Venkatesan, V.2    Rasool, M.3
  • 40
    • 84878136101 scopus 로고    scopus 로고
    • Total phenolic, flavonoid contents and in vitro antioxidant activity of Dioscorea alata L. tuber
    • Sakthidevi G., Mohan V.R. Total phenolic, flavonoid contents and in vitro antioxidant activity of Dioscorea alata L. tuber. Journal of Pharmaceutical Sciences and Research 2013, 5:115-119.
    • (2013) Journal of Pharmaceutical Sciences and Research , vol.5 , pp. 115-119
    • Sakthidevi, G.1    Mohan, V.R.2
  • 44
    • 33745194553 scopus 로고    scopus 로고
    • Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation
    • Stentz F.B., Kitabchi A.E. Palmitic acid-induced activation of human T-lymphocytes and aortic endothelial cells with production of insulin receptors, reactive oxygen species, cytokines, and lipid peroxidation. Biochemical and Biophysical Research Communications 2006, 346:721-726.
    • (2006) Biochemical and Biophysical Research Communications , vol.346 , pp. 721-726
    • Stentz, F.B.1    Kitabchi, A.E.2
  • 45
    • 33745123647 scopus 로고    scopus 로고
    • Capillary electrophoresis of the active ingredients of Dioscorea bulbifera L. and its medicinal preparations
    • Tang Z., Zhou Y., Zeng Y., Zang S., He P., Fang Y. Capillary electrophoresis of the active ingredients of Dioscorea bulbifera L. and its medicinal preparations. Chromatographia 2006, 63:617-622.
    • (2006) Chromatographia , vol.63 , pp. 617-622
    • Tang, Z.1    Zhou, Y.2    Zeng, Y.3    Zang, S.4    He, P.5    Fang, Y.6
  • 46
    • 80054039736 scopus 로고    scopus 로고
    • Analysis and identification of phenolic compounds in Dioscorea hispida Dennst
    • Theerasin S., Baker A.T. Analysis and identification of phenolic compounds in Dioscorea hispida Dennst. Asian Journal of Agricultural and Food Sciences 2009, 2:547-560.
    • (2009) Asian Journal of Agricultural and Food Sciences , vol.2 , pp. 547-560
    • Theerasin, S.1    Baker, A.T.2
  • 48
    • 84928572516 scopus 로고    scopus 로고
    • Transcriptome analysis reveals flavonoid biosynthesis regulation and simple sequence repeats in yam (Dioscorea alata L.) tubers
    • Wu Z., Jiang W., Mantri N., Bao X., Chen S., Tao Z. Transcriptome analysis reveals flavonoid biosynthesis regulation and simple sequence repeats in yam (Dioscorea alata L.) tubers. BMC Genomics 2015, 16:346.
    • (2015) BMC Genomics , vol.16 , pp. 346
    • Wu, Z.1    Jiang, W.2    Mantri, N.3    Bao, X.4    Chen, S.5    Tao, Z.6
  • 49
    • 33846867711 scopus 로고    scopus 로고
    • Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects
    • Zhao G., Etherton T.D., Martin K.R., Gillies P.J., West S.G., Kris-Etherton P.M. Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. The American Journal of Clinical Nutrition 2007, 85:385-391.
    • (2007) The American Journal of Clinical Nutrition , vol.85 , pp. 385-391
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    Gillies, P.J.4    West, S.G.5    Kris-Etherton, P.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.