Bioactive food components prevent carcinogenic stress via Nrf2 activation in BRCA1 deficient breast epithelial cells

Toxicology Letters

Volumn 209, Issue 2, 2012, Pages 154-160

  Kang, Hyo Jin ^a   Hong, Young Bin ^a,b   Kim, Hee Jeong ^a   Wang, Antai ^c   Bae, Insoo ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b Dankook University   (South Korea)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Bioactive food components; BRCA1; Carcinogenesis; Chemoprevention; Nrf2; Oxidative stress

Indexed keywords

BENZO[A]PYRENE; BRCA1 PROTEIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; BREAST EPITHELIUM; CANCER PREVENTION; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVATION; FOOD COMPOSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RISK REDUCTION; XENOBIOTIC STRESS;

ANTICARCINOGENIC AGENTS; BENZO(A)PYRENE; BLOTTING, WESTERN; BRCA1 PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; EPITHELIAL CELLS; FEMALE; HUMANS; NF-E2-RELATED FACTOR 2; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; THIOCYANATES;

EID: 84862778902     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.12.002     Document Type: Article

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