Author Correction: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors (Nature Cell Biology, (2017), 19, 9, (1037-1048), 10.1038/ncb3598);ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors

Nature Cell Biology

Volumn 19, Issue 9, 2017, Pages 1037-1048

  Skamagki, Maria ^a   Correia, Cristina ^b   Yeung, Percy ^c   Baslan, Timour ^a   Beck, Samuel ^d   Zhang, Cheng ^b   Ross, Christian A ^b   Dang, Lam ^a   Liu, Zhong ^e   Giunta, Simona ^f   Chang, Tzu Pei ^a   Wang, Joye ^a   Ananthanarayanan, Aparna ^a   Bohndorf, Martina ^g   Bosbach, Benedikt ^a   Adjaye, James ^g   Funabiki, Hironori ^f   Kim, Jonghwan ^d   Lowe, Scott ^a   Collins, James J ^h   Lu, Chi Wei ^c   Li, Hu ^b   Zhao, Rui ^e   Kim, Kitai ^a   more..

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c CHILD HEALTH INSTITUTE OF NEW JERSEY   (United States)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f ROCKEFELLER UNIVERSITY   (United States)

^g HEINRICH HEINE UNIVERSITY   (Germany)

^h HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZSCAN10 PROTEIN; DNA BINDING PROTEIN; KRUPPEL LIKE FACTOR; MYC PROTEIN, HUMAN; POU5F1 PROTEIN, HUMAN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX; ZFP206 PROTEIN, MOUSE; ZNF206 PROTEIN, HUMAN;

ADULT; AGED; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DONOR; EMBRYO; FEMALE; GENOMIC INSTABILITY; HOMEOSTASIS; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REACTIVE OXYGEN SPECIES GLUTATHIONE HOMEOSTASIS; YOUNG ADULT; ADULT STEM CELL; AGE; AGING; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REPROGRAMMING TECHNIQUE; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GESTATIONAL AGE; METABOLISM; NEWBORN; OXIDATIVE STRESS; PATHOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADULT STEM CELLS; AGE FACTORS; AGED; AGING; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; CELLULAR REPROGRAMMING TECHNIQUES; DNA DAMAGE; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMIC INSTABILITY; GESTATIONAL AGE; GLUTATHIONE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICE, TRANSGENIC; OCTAMER TRANSCRIPTION FACTOR-3; OXIDATIVE STRESS; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-MYC; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TISSUE DONORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 85028673415     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/s41556-018-0269-y     Document Type: Erratum

References (65)

1. Prigione, A., et al. Mitochondrial-associated cell death mechanisms are reset to an embryonic-like state in aged donor-derived iPS cells harboring chromosomal aberrations. PLoS ONE 6, e27352 (2011
2. Kang, E., et al. Age-related accumulation of somatic mitochondrial DNA mutations in adult-derived human iPSCs. Cell Stem Cell 18, 625-636 (2016
3. Lo Sardo, V., et al. Influence of donor age on induced pluripotent stem cells. Nat. Biotechnol. 35, 69-74 (2016
4. Garber, K. RIKEN suspends first clinical trial involving induced pluripotent stem cells. Nat. Biotechnol. 33, 890-891 (2015
5. Coghlan, A. Unexpected mutations put stem cell trial on hold. New Sci. 227, 9 (2015
6. Kang, E., et al. Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations. Nature 540, 270-275 (2016
7. Mandai, M., et al. Autologous induced stem-cell-derived retinal cells for macular degeneration. New Engl. J. Med. 376, 1038-1046 (2017
8. Holmstrom, K. M., & Finkel, T. Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat. Rev. Mol. Cell Biol. 15, 411-421 (2014
9. Bigarella, C. L., Liang, R., & Ghaffari, S. Stem cells and the impact of ROS signaling. Development 141, 4206-4218 (2014
10. Liochev, S. I. Reactive oxygen species and the free radical theory of aging. Free Radic. Biol. Med. 60, 1-4 (2013
11. Baccelli, I., & Trumpp, A. The evolving concept of cancer and metastasis stem cells. J. Cell Biol. 198, 281-293 (2012
12. Alfadda, A. A., & Sallam, R. M. Reactive oxygen species in health and disease. J. Biomed. Biotechnol. 2012, 936486 (2012
13. Sleigh, M. J. The mechanism of DNA breakage by phleomycin in vitro. Nucl. Acids Res. 3, 891-901 (1976
14. Franco, R., & Cidlowski, J. A. Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ. 16, 1303-1314 (2009
15. Harris, I. S., et al. Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell 27, 211-222 (2015
16. Guo, Z., Kozlov, S., Lavin, M. F., Person, M. D., & Paull, T. T. ATM activation by oxidative stress. Science 330, 517-521 (2010
17. Takahashi, K., & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676 (2006
18. Smith, K. P., Luong, M. X., & Stein, G. S. Pluripotency: toward a gold standard for human ES and iPS cells. J. Cell Physiol. 220, 21-29 (2009
19. Kim, K., et al. Epigenetic memory in induced pluripotent stem cells. Nature 467, 285-290 (2010
20. Liu, J. C., Lerou, P. H., & Lahav, G. Stem cells: balancing resistance and sensitivity to DNA damage. Trends Cell Biol. 24, 268-274 (2014
21. Liu, J. C., et al. High mitochondrial priming sensitizes hESCs to DNA-damageinduced apoptosis. Cell Stem Cell 13, 483-491 (2013
22. Zhivotovsky, B., & Kroemer, G. Apoptosis and genomic instability. Nat. Rev. Mol. Cell Biol. 5, 752-762 (2004
23. Gurdon, J. B., & Wilmut, I. Nuclear transfer to eggs and oocytes. Cold Spring Harb. Perspect. Biol. 3, 1-14 (2011
24. Ma, H., et al. Abnormalities in human pluripotent cells due to reprogramming mechanisms. Nature 511, 177-183 (2014
25. Cowan, C. A., Atienza, J., Melton, D. A., & Eggan, K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309, 1369-1373 (2005
26. Kim, J., Chu, J., Shen, X., Wang, J., & Orkin, S. H. An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061 (2008
27. Yu, H. B., Kunarso, G., Hong, F. H., & Stanton, L. W. Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells. J. Biol. Chem. 284, 31327-31335 (2009
28. Zhang, W., et al. Zfp206 regulates ES cell gene expression and differentiation. Nucl. Acids Res. 34, 4780-4790 (2006
29. Ford, J., Ahmed, S., Allison, S., Jiang, M., & Milner, J. JNK2-dependent regulation of SIRT1 protein stability. Cell Cycle 7, 3091-3097 (2008
30. Jiang, J., et al. Zscan4 promotes genomic stability during reprogramming and dramatically improves the quality of iPS cells as demonstrated by tetraploid complementation. Cell Res. 23, 92-106 (2013
31. Chan, E. M., et al. Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nat. Biotechnol. 27, 1033-1037 (2009
32. Tsuda, H., Sasaki, K., & Tanaka, N. Establishment of hypoxanthine phosphoribosyltransferase(HPRT)-locus mutation assay system in mouse ES cells. Altern. Anim. Test. Exp. 11, 118-128 (2005
33. Balendiran, G. K., Dabur, R., & Fraser, D. The role of glutathione in cancer. Cell Biochem. Funct. 22, 343-352 (2004
34. Estrela, J. M., Ortega, A., & Obrador, E. Glutathione in cancer biology and therapy. Crit. Rev. Clin. Lab. Sci. 43, 143-181 (2006
35. Traverso, N., et al. Role of glutathione in cancer progression and chemoresistance. Oxid. Med. Cell. Longev. 2013, 972913 (2013
36. Miller, J. D., et al. Human iPSC-based modeling of late-onset disease via progerininduced aging. Cell Stem Cell 13, 691-705 (2013
37. Kyttala, A., et al. Genetic variability overrides the impact of parental cell type and determines iPSC differentiation potential. Stem Cell Rep. 6, 200-212 (2016
38. Takahashi, K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007
39. Nakagawa, M., et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26, 101-106 (2008
40. Araki, R., et al. Crucial role of c-Myc in the generation of induced pluripotent stem cells. Stem Cells 29, 1362-1370 (2011
41. Okita, K., et al. A more efficient method to generate integration-free human iPS cells. Nat. Methods 8, 409-412 (2011
42. Unternaehrer, J. J., et al. The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming. Stem Cell Rep. 3, 691-698 (2014
43. Baslan, T., et al. Optimizing sparse sequencing of single cells for highly multiplex copy number profiling. Genome Res. 25, 714-724 (2015
44. Yamamoto, S., et al. Rapid selection of XO embryonic stem cells using Y chromosomelinked GFP transgenic mice. Transgenic Res. 23, 757-765 (2014
45. Seol, H. W., et al. Separation and maintenance of normal cells from human embryonic stem cells with trisomy 12 mosaicism. Chromosome Res. 16, 1075-1084 (2008
46. Kilpinen, H., et al. Common genetic variation drives molecular heterogeneity in human iPSCs. Nature 546, 370-375 (2017
47. Finkel, T., & Holbrook, N. J. Oxidants, oxidative stress and the biology of ageing. Nature 408, 239-247 (2000
48. Shaw, P. X., Werstuck, G., & Chen, Y. Oxidative stress and aging diseases. Oxid. Med. Cell. Longev. 2014, 569146 (2014
49. Son, J., et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature 496, 101-105 (2013
50. Hollander, M., & Wolfe, D. A. Nonparametric Statistical Methods (Wiley, 1973
51. Kim, K., et al. Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat. Biotechnol. 29, 1117-1119 (2011
52. Johnson, G. E. Mammalian cell HPRT gene mutation assay: test methods. Methods Mol. Biol. 817, 55-67 (2012
53. Rass, E., Chandramouly, G., Zha, S., Alt, F. W., & Xie, A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J. Biol. Chem. 288, 7086-7095 (2013
54. Hahn, P., Kapp, L. N., & Painter, R. B. Establishment and characterization of two human cell lines with amplified dihydrofolate reductase genes. Exp. Cell Res. 168, 89-94 (1987
55. Tian, B., Yang, J., & Brasier, A. R. Two-step cross-linking for analysis of protein-chromatin interactions. Methods Mol. Biol. 809, 105-120 (2012
56. Buzzard, J. J., Gough, N. M., Crook, J. M., & Colman, A. Karyotype of human ES cells during extended culture. Nat. Biotechnol. 22, 381-382 (2004
57. Imreh, M. P., et al. In vitro culture conditions favoring selection of chromosomal abnormalities in human ES cells. J. Cell. Biochem. 99, 508-516 (2006
58. Li, S. S., et al. Characterization and gene expression profiling of five new human embryonic stem cell lines derived in Taiwan. Stem Cells Dev. 15, 532-555 (2006
59. Plaia, T. W., et al. Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research. Stem Cells 24, 531-546 (2006
60. Altmann, H. M., et al. Homozygous/compound heterozygous triadin mutations associated with autosomal-recessive long-QT syndrome and pediatric sudden cardiac arrest: elucidation of the triadin knockout syndrome. Circulation 131, 2051-2060 (2015
61. Chiang, C., et al. SpeedSeq: ultra-fast personal genome analysis and interpretation. Nat. Methods 12, 966-968 (2015
62. Li, Y., et al. Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat. Genet. 42, 969-972 (2010
63. The 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010
64. The 1000 Genomes Project Consortium An integrated map of genetic variation from 1,092 human genomes. Nature 491, 56-65 (2012
65. Kocher, J. P., et al. The Biological Reference Repository (BioR): a rapid and flexible system for genomics annotation. Bioinformatics 30, 1920-1922 (2014