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Volumn 7, Issue JUL, 2017, Pages

Cytokines and chemokines in cerebral malaria pathogenesis

Author keywords

Blood brain barrier; Cerebral malaria; Chemokines; Cytokines; Endothelial activation; Malaria; Neuroinflammation; Plasmodium

Indexed keywords

CHEMOKINE; CYTOKINE;

EID: 85027568558     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2017.00324     Document Type: Review
Times cited : (185)

References (159)
  • 1
    • 84894234581 scopus 로고    scopus 로고
    • Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains
    • Adams, Y., Kuhnrae, P., Higgins, M. K., Ghumra, A., and Rowe, J. A. (2014). Rosetting Plasmodium falciparum-infected erythrocytes bind to human brain microvascular endothelial cells in vitro, demonstrating a dual adhesion phenotype mediated by distinct P. falciparum erythrocyte membrane protein 1 domains. Infect. Immun. 82, 949–959. doi: 10.1128/IAI.01233-13
    • (2014) Infect. Immun. , vol.82 , pp. 949-959
    • Adams, Y.1    Kuhnrae, P.2    Higgins, M.K.3    Ghumra, A.4    Rowe, J.A.5
  • 2
    • 65349181325 scopus 로고    scopus 로고
    • The pathophysiology of vivax malaria
    • Anstey, N. M., Russell, B., Yeo, T. W., and Price, R. N. (2009). The pathophysiology of vivax malaria. Trends Parasitol. 25, 220–227. doi: 10.1016/j.pt.2009.02.003
    • (2009) Trends Parasitol. , vol.25 , pp. 220-227
    • Anstey, N.M.1    Russell, B.2    Yeo, T.W.3    Price, R.N.4
  • 3
    • 38049009931 scopus 로고    scopus 로고
    • Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children
    • Armah, H. B., Wilson, N. O., Sarfo, B. Y., Powell, M. D., Bond, V. C., Anderson, W., et al. (2007). Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar. J. 6:147. doi: 10.1186/1475-2875-6-147
    • (2007) Malar. J. , vol.6
    • Armah, H.B.1    Wilson, N.O.2    Sarfo, B.Y.3    Powell, M.D.4    Bond, V.C.5    Anderson, W.6
  • 4
    • 84949604316 scopus 로고    scopus 로고
    • Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: possible role in cerebral malaria
    • Bakmiwewa, S. M., Weiser, S., Grey, M., Heng, B., Guillemin, G. J., Ball, H. J., et al. (2016). Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: possible role in cerebral malaria. Cytokine 78, 79–86. doi: 10.1016/j.cyto.2015.11.024
    • (2016) Cytokine , vol.78 , pp. 79-86
    • Bakmiwewa, S.M.1    Weiser, S.2    Grey, M.3    Heng, B.4    Guillemin, G.J.5    Ball, H.J.6
  • 5
    • 85014351357 scopus 로고    scopus 로고
    • miR-155 modifies inflammation, endothelial activation and blood-brain barrier dysfunction in cerebral malaria
    • Barker, K. R., Lu, Z., Kim, H., Zheng, Y., Chen, J., Conroy, A. L., et al. (2017). miR-155 modifies inflammation, endothelial activation and blood-brain barrier dysfunction in cerebral malaria. Mol. Med. 23, 24–33. doi: 10.2119/molmed.2016.00139
    • (2017) Mol. Med. , vol.23 , pp. 24-33
    • Barker, K.R.1    Lu, Z.2    Kim, H.3    Zheng, Y.4    Chen, J.5    Conroy, A.L.6
  • 6
    • 0028072587 scopus 로고
    • Stimulators of tumour necrosis factor production released by damaged erythrocytes
    • Bate, C. A., and Kwiatkowski, D. P. (1994). Stimulators of tumour necrosis factor production released by damaged erythrocytes. Immunology 83, 256–261.
    • (1994) Immunology , vol.83 , pp. 256-261
    • Bate, C.A.1    Kwiatkowski, D.P.2
  • 7
    • 0040078401 scopus 로고    scopus 로고
    • Regulation of endothelial cell adhesion molecule expression in an experimental model of cerebral malaria
    • Bauer, P. R., Van Der Heyde, H. C., Sun, G., Specian, R. D., and Granger, D. N. (2002). Regulation of endothelial cell adhesion molecule expression in an experimental model of cerebral malaria. Microcirculation 9, 463–470. doi: 10.1038/sj.mn.7800159
    • (2002) Microcirculation , vol.9 , pp. 463-470
    • Bauer, P.R.1    Van Der Heyde, H.C.2    Sun, G.3    Specian, R.D.4    Granger, D.N.5
  • 8
    • 58849132997 scopus 로고    scopus 로고
    • Perfusion abnormalities in children with cerebral malaria and malarial retinopathy
    • Beare, N. A., Harding, S. P., Taylor, T. E., Lewallen, S., and Molyneux, M. E. (2009). Perfusion abnormalities in children with cerebral malaria and malarial retinopathy. J. Infect. Dis. 199, 263–271. doi: 10.1086/595735
    • (2009) J. Infect. Dis. , vol.199 , pp. 263-271
    • Beare, N.A.1    Harding, S.P.2    Taylor, T.E.3    Lewallen, S.4    Molyneux, M.E.5
  • 9
    • 33947433233 scopus 로고    scopus 로고
    • Malarial retinopathy: a newly established diagnostic sign in severe malaria
    • Beare, N. A., Taylor, T. E., Harding, S. P., Lewallen, S., and Molyneux, M. E. (2006). Malarial retinopathy: a newly established diagnostic sign in severe malaria. Am. J. Trop. Med. Hyg. 75, 790–797. doi: 10.4269/ajtmh.2006.75.790
    • (2006) Am. J. Trop. Med. Hyg. , vol.75 , pp. 790-797
    • Beare, N.A.1    Taylor, T.E.2    Harding, S.P.3    Lewallen, S.4    Molyneux, M.E.5
  • 10
    • 84975720714 scopus 로고    scopus 로고
    • Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
    • Beeson, J. G., Drew, D. R., Boyle, M. J., Feng, G., Fowkes, F. J., and Richards, J. S. (2016). Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria. FEMS Microbiol. Rev. 40, 343–372. doi: 10.1093/femsre/fuw001
    • (2016) FEMS Microbiol. Rev. , vol.40 , pp. 343-372
    • Beeson, J.G.1    Drew, D.R.2    Boyle, M.J.3    Feng, G.4    Fowkes, F.J.5    Richards, J.S.6
  • 11
    • 0038103797 scopus 로고    scopus 로고
    • Chemokine receptor CCR2 is not essential for the development of experimental cerebral malaria
    • Belnoue, E., Costa, F. T., Vigario, A. M., Voza, T., Gonnet, F., Landau, I., et al. (2003). Chemokine receptor CCR2 is not essential for the development of experimental cerebral malaria. Infect. Immun. 71, 3648–3651. doi: 10.1128/IAI.71.6.3648-3651.2003
    • (2003) Infect. Immun. , vol.71 , pp. 3648-3651
    • Belnoue, E.1    Costa, F.T.2    Vigario, A.M.3    Voza, T.4    Gonnet, F.5    Landau, I.6
  • 12
    • 84973343099 scopus 로고    scopus 로고
    • Severe adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomass
    • Bernabeu, M., Danziger, S. A., Avril, M., Vaz, M., Babar, P. H., Brazier, A. J., et al. (2016). Severe adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomass. Proc. Natl. Acad. Sci. U.S.A. 113, E3270–E3279. doi: 10.1073/pnas.1524294113
    • (2016) Proc. Natl. Acad. Sci. U.S.A. , vol.113 , pp. E3270-E3279
    • Bernabeu, M.1    Danziger, S.A.2    Avril, M.3    Vaz, M.4    Babar, P.H.5    Brazier, A.J.6
  • 13
    • 85007578581 scopus 로고    scopus 로고
    • EPCR and malaria severity: the center of a perfect storm
    • Bernabeu, M., and Smith, J.D. (2017). EPCR and malaria severity: the center of a perfect storm. Trends Parasitol. 33, 295–308. doi: 10.1016/j.pt.2016.11.004
    • (2017) Trends Parasitol. , vol.33 , pp. 295-308
    • Bernabeu, M.1    Smith, J.D.2
  • 14
    • 34249318067 scopus 로고    scopus 로고
    • Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis
    • Bozza, F. A., Salluh, J. I., Japiassu, A. M., Soares, M., Assis, E. F., Gomes, R. N., et al. (2007). Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit. Care 11, R49. doi: 10.1186/cc5783
    • (2007) Crit. Care , vol.11 , pp. R49
    • Bozza, F.A.1    Salluh, J.I.2    Japiassu, A.M.3    Soares, M.4    Assis, E.F.5    Gomes, R.N.6
  • 15
    • 0032806215 scopus 로고    scopus 로고
    • Evidence of blood-brain barrier dysfunction in human cerebral malaria
    • Brown, H., Hien, T. T., Day, N., Mai, N. T., Chuong, L. V., Chau, T. T., et al. (1999). Evidence of blood-brain barrier dysfunction in human cerebral malaria. Neuropathol. Appl. Neurobiol. 25, 331–340. doi: 10.1046/j.1365-2990.1999.00188.x
    • (1999) Neuropathol. Appl. Neurobiol. , vol.25 , pp. 331-340
    • Brown, H.1    Hien, T.T.2    Day, N.3    Mai, N.T.4    Chuong, L.V.5    Chau, T.T.6
  • 17
    • 84958105971 scopus 로고    scopus 로고
    • Malaria-derived hemozoin exerts early modulatory effects on the phenotype and maturation of human dendritic cells
    • Bujila, I., Schwarzer, E., Skorokhod, O., Weidner, J. M., Troye-Blomberg, M., and Ostlund Farrants, A. K. (2016). Malaria-derived hemozoin exerts early modulatory effects on the phenotype and maturation of human dendritic cells. Cell. Microbiol. 18, 413–423. doi: 10.1111/cmi.12521
    • (2016) Cell. Microbiol. , vol.18 , pp. 413-423
    • Bujila, I.1    Schwarzer, E.2    Skorokhod, O.3    Weidner, J.M.4    Troye-Blomberg, M.5    Ostlund Farrants, A.K.6
  • 18
    • 42449135821 scopus 로고    scopus 로고
    • Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria
    • Campanella, G. S., Tager, A. M., El Khoury, J. K., Thomas, S. Y., Abrazinski, T. A., Manice, L. A., et al. (2008). Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria. Proc. Natl. Acad. Sci. U.S.A. 105, 4814–4819. doi: 10.1073/pnas.0801544105
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 4814-4819
    • Campanella, G.S.1    Tager, A.M.2    El Khoury, J.K.3    Thomas, S.Y.4    Abrazinski, T.A.5    Manice, L.A.6
  • 20
    • 85006810409 scopus 로고    scopus 로고
    • Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria
    • Capuccini, B., Lin, J., Talavera-Lopez, C., Khan, S. M., Sodenkamp, J., Spaccapelo, R., et al. (2016). Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria. Sci. Rep. 6:39258. doi: 10.1038/srep39258
    • (2016) Sci. Rep. , vol.6
    • Capuccini, B.1    Lin, J.2    Talavera-Lopez, C.3    Khan, S.M.4    Sodenkamp, J.5    Spaccapelo, R.6
  • 21
    • 0024513740 scopus 로고
    • Endothelial cell activation induced by tumor necrosis factor and lymphotoxin
    • Cavender, D. E., Edelbaum, D., and Ziff, M. (1989). Endothelial cell activation induced by tumor necrosis factor and lymphotoxin. Am. J. Pathol. 134, 551–560.
    • (1989) Am. J. Pathol. , vol.134 , pp. 551-560
    • Cavender, D.E.1    Edelbaum, D.2    Ziff, M.3
  • 22
    • 34249932411 scopus 로고    scopus 로고
    • Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: pathogenic or protective
    • Chakravorty, S. J., Carret, C., Nash, G. B., Ivens, A., Szestak, T., and Craig, A. G. (2007). Altered phenotype and gene transcription in endothelial cells, induced by Plasmodium falciparum-infected red blood cells: pathogenic or protective? Int. J. Parasitol. 37, 975–987. doi: 10.1016/j.ijpara.2007.02.006
    • (2007) Int. J. Parasitol. , vol.37 , pp. 975-987
    • Chakravorty, S.J.1    Carret, C.2    Nash, G.B.3    Ivens, A.4    Szestak, T.5    Craig, A.G.6
  • 23
    • 0033923163 scopus 로고    scopus 로고
    • Molecular aspects of severe malaria
    • Chen, Q., Schlichtherle, M., and Wahlgren, M. (2000). Molecular aspects of severe malaria. Clin. Microbiol. Rev. 13, 439–450. doi: 10.1128/CMR.13.3.439-450.2000
    • (2000) Clin. Microbiol. Rev. , vol.13 , pp. 439-450
    • Chen, Q.1    Schlichtherle, M.2    Wahlgren, M.3
  • 24
    • 3242802125 scopus 로고    scopus 로고
    • Pathogenesis of malaria and clinically similar conditions
    • Clark, I. A., Alleva, L. M., Mills, A. C., andCowden, W. B. (2004). Pathogenesis of malaria and clinically similar conditions. Clin. Microbiol. Rev. 17, 509–539. doi: 10.1128/CMR.17.3.509-539.2004
    • (2004) Clin. Microbiol. Rev. , vol.17 , pp. 509-539
    • Clark, I.A.1    Alleva, L.M.2    Mills, A.C.3    Cowden, W.B.4
  • 25
    • 33750625136 scopus 로고    scopus 로고
    • Human malarial disease: a consequence of inflammatory cytokine release
    • Clark, I. A., Budd, A. C., Alleva, L. M., and Cowden, W. B. (2006). Human malarial disease: a consequence of inflammatory cytokine release. Malar. J. 5:85. doi: 10.1186/1475-2875-5-85
    • (2006) Malar. J. , vol.5
    • Clark, I.A.1    Budd, A.C.2    Alleva, L.M.3    Cowden, W.B.4
  • 26
    • 0028059912 scopus 로고
    • The cytokine theory of human cerebral malaria
    • Clark, I. A., and Rockett, K. A. (1994). The cytokine theory of human cerebral malaria. Parasitol. Today 10, 410–412. doi: 10.1016/0169-4758(94)90237-2
    • (1994) Parasitol. Today , vol.10 , pp. 410-412
    • Clark, I.A.1    Rockett, K.A.2
  • 27
    • 85018331636 scopus 로고    scopus 로고
    • The meteorology of cytokine storms, and the clinical usefulness of this knowledge
    • Clark, I.A., and Vissel, B. (2017). The meteorology of cytokine storms, and the clinical usefulness of this knowledge. Semin. Immunopathol. 39, 505–516. doi: 10.1007/s00281-017-0628-y
    • (2017) Semin. Immunopathol. , vol.39 , pp. 505-516
    • Clark, I.A.1    Vissel, B.2
  • 28
    • 19944430901 scopus 로고    scopus 로고
    • Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
    • Coban, C., Ishii, K. J., Kawai, T., Hemmi, H., Sato, S., Uematsu, S., et al. (2005). Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J. Exp. Med. 201, 19–25. doi: 10.1084/jem.20041836
    • (2005) J. Exp. Med. , vol.201 , pp. 19-25
    • Coban, C.1    Ishii, K.J.2    Kawai, T.3    Hemmi, H.4    Sato, S.5    Uematsu, S.6
  • 29
    • 77952289572 scopus 로고    scopus 로고
    • Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis
    • Combes, V., El-Assaad, F., Faille, D., Jambou, R., Hunt, N. H., and Grau, G. E. (2010). Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Prog. Neurobiol. 91, 140–151. doi: 10.1016/j.pneurobio.2010.01.007
    • (2010) Prog. Neurobiol. , vol.91 , pp. 140-151
    • Combes, V.1    El-Assaad, F.2    Faille, D.3    Jambou, R.4    Hunt, N.H.5    Grau, G.E.6
  • 30
    • 77649221389 scopus 로고    scopus 로고
    • Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation
    • Couper, K. N., Barnes, T., Hafalla, J. C., Combes, V., Ryffel, B., Secher, T., et al. (2010). Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. PLoS Pathog. 6:e1000744. doi: 10.1371/journal.ppat.1000744
    • (2010) PLoS Pathog. , vol.6
    • Couper, K.N.1    Barnes, T.2    Hafalla, J.C.3    Combes, V.4    Ryffel, B.5    Secher, T.6
  • 32
    • 84965083897 scopus 로고    scopus 로고
    • Antimalarial drug resistance: literature review and activities and findings of the ICEMR network
    • Cui, L., Mharakurwa, S., Ndiaye, D., Rathod, P. K., and Rosenthal, P. J. (2015). Antimalarial drug resistance: literature review and activities and findings of the ICEMR network. Am. J. Trop. Med. Hyg. 93, 57–68. doi: 10.4269/ajtmh.15-0007
    • (2015) Am. J. Trop. Med. Hyg. , vol.93 , pp. 57-68
    • Cui, L.1    Mharakurwa, S.2    Ndiaye, D.3    Rathod, P.K.4    Rosenthal, P.J.5
  • 34
    • 0036213195 scopus 로고    scopus 로고
    • Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis
    • de Souza, J. B., and Riley, E. M. (2002). Cerebral malaria: the contribution of studies in animal models to our understanding of immunopathogenesis. Microbes Infect. 4, 291–300. doi: 10.1016/S1286-4579(02)01541-1
    • (2002) Microbes Infect. , vol.4 , pp. 291-300
    • de Souza, J.B.1    Riley, E.M.2
  • 35
    • 0028912884 scopus 로고
    • Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children
    • Di Perri, G., Di Perri, I. G., Monteiro, G. B., Bonora, S., Hennig, C., Cassatella, M., et al. (1995). Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children. J. Infect. Dis. 171, 1317–1322. doi: 10.1093/infdis/171.5.1317
    • (1995) J. Infect. Dis. , vol.171 , pp. 1317-1322
    • Di Perri, G.1    Di Perri, I.G.2    Monteiro, G.B.3    Bonora, S.4    Hennig, C.5    Cassatella, M.6
  • 36
    • 78449267241 scopus 로고    scopus 로고
    • Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
    • Dondorp, A. M., Fanello, C. I., Hendriksen, I. C., Gomes, E., Seni, A., Chhaganlal, K. D., et al. (2010). Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet 376, 1647–1657. doi: 10.1016/S0140-6736(10)61924-1
    • (2010) Lancet , vol.376 , pp. 1647-1657
    • Dondorp, A.M.1    Fanello, C.I.2    Hendriksen, I.C.3    Gomes, E.4    Seni, A.5    Chhaganlal, K.D.6
  • 37
    • 39349102894 scopus 로고    scopus 로고
    • Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria
    • Dondorp, A. M., Ince, C., Charunwatthana, P., Hanson, J., Van Kuijen, A., Faiz, M. A., et al. (2008). Direct in vivo assessment of microcirculatory dysfunction in severe falciparum malaria. J. Infect. Dis. 197, 79–84. doi: 10.1086/523762
    • (2008) J. Infect. Dis. , vol.197 , pp. 79-84
    • Dondorp, A.M.1    Ince, C.2    Charunwatthana, P.3    Hanson, J.4    Van Kuijen, A.5    Faiz, M.A.6
  • 38
    • 1642565100 scopus 로고    scopus 로고
    • Reduced microcirculatory flow in severe falciparum malaria: pathophysiology and electron-microscopic pathology
    • Dondorp, A. M., Pongponratn, E., and White, N. J. (2004). Reduced microcirculatory flow in severe falciparum malaria: pathophysiology and electron-microscopic pathology. Acta Trop. 89, 309–317. doi: 10.1016/j.actatropica.2003.10.004
    • (2004) Acta Trop. , vol.89 , pp. 309-317
    • Dondorp, A.M.1    Pongponratn, E.2    White, N.J.3
  • 40
    • 0035153212 scopus 로고    scopus 로고
    • Immune function of astrocytes
    • Dong, Y., and Benveniste, E. N. (2001). Immune function of astrocytes. Glia 36, 180–190. doi: 10.1002/glia.1107
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 41
    • 0037141025 scopus 로고    scopus 로고
    • Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria
    • Engwerda, C. R., Mynott, T. L., Sawhney, S., De Souza, J. B., Bickle, Q. D., and Kaye, P. M. (2002). Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J. Exp. Med. 195, 1371–1377. doi: 10.1084/jem.20020128
    • (2002) J. Exp. Med. , vol.195 , pp. 1371-1377
    • Engwerda, C.R.1    Mynott, T.L.2    Sawhney, S.3    De Souza, J.B.4    Bickle, Q.D.5    Kaye, P.M.6
  • 42
    • 84944747708 scopus 로고    scopus 로고
    • Toll-like Receptors and malaria: sensing and susceptibility
    • Eriksson, E. M., Sampaio, N. G., and Schofield, L. (2013). Toll-like Receptors and malaria: sensing and susceptibility. J. Trop. Dis. 2:126. doi: 10.4172/2329-891X.1000126
    • (2013) J. Trop. Dis. , vol.2
    • Eriksson, E.M.1    Sampaio, N.G.2    Schofield, L.3
  • 43
    • 84929944191 scopus 로고    scopus 로고
    • Fever and the thermal regulation of immunity: the immune system feels the heat
    • Evans, S. S., Repasky, E. A., and Fisher, D. T. (2015). Fever and the thermal regulation of immunity: the immune system feels the heat. Nat. Rev. Immunol. 15, 335–349. doi: 10.1038/nri3843
    • (2015) Nat. Rev. Immunol. , vol.15 , pp. 335-349
    • Evans, S.S.1    Repasky, E.A.2    Fisher, D.T.3
  • 44
    • 0032695542 scopus 로고    scopus 로고
    • Role of ICAM-1 (CD54) in the development of murine cerebral malaria
    • Favre, N., Da Laperousaz, C., Ryffel, B., Weiss, N. A., Imhof, B. A., Rudin, W., et al. (1999). Role of ICAM-1 (CD54) in the development of murine cerebral malaria. Microbes Infect. 1, 961–968. doi: 10.1016/S1286-4579(99)80513-9
    • (1999) Microbes Infect. , vol.1 , pp. 961-968
    • Favre, N.1    Da Laperousaz, C.2    Ryffel, B.3    Weiss, N.A.4    Imhof, B.A.5    Rudin, W.6
  • 45
    • 0030879653 scopus 로고    scopus 로고
    • Hemoglobin metabolism in the malaria parasite Plasmodium falciparum
    • Francis, S. E., Sullivan, J. Jr., and Goldberg, D.E. (1997). Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu. Rev. Microbiol. 51, 97–123. doi: 10.1146/annurev.micro.51.1.97
    • (1997) Annu. Rev. Microbiol. , vol.51 , pp. 97-123
    • Francis, S.E.1    Sullivan, J.2    Goldberg, D.E.3
  • 47
    • 57549095016 scopus 로고    scopus 로고
    • Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites
    • Gilson, P. R., and Crabb, B. S. (2009). Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites. Int. J. Parasitol. 39, 91–96. doi: 10.1016/j.ijpara.2008.09.007
    • (2009) Int. J. Parasitol. , vol.39 , pp. 91-96
    • Gilson, P.R.1    Crabb, B.S.2
  • 48
    • 36349016500 scopus 로고    scopus 로고
    • TLR-mediated cell signaling by malaria GPIs
    • Gowda, D. C. (2007). TLR-mediated cell signaling by malaria GPIs. Trends Parasitol. 23, 596–604. doi: 10.1016/j.pt.2007.09.003
    • (2007) Trends Parasitol. , vol.23 , pp. 596-604
    • Gowda, D.C.1
  • 49
    • 0025781820 scopus 로고
    • Late administration of monoclonal antibody to leukocyte functionantigen 1 abrogates incipient murine cerebral malaria
    • Grau, G. E., Pointaire, P., Piguet, P. F., Vesin, C., Rosen, H., Stamenkovic, I., et al. (1991). Late administration of monoclonal antibody to leukocyte functionantigen 1 abrogates incipient murine cerebral malaria. Eur. J. Immunol. 21, 2265–2267. doi: 10.1002/eji.1830210939
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2265-2267
    • Grau, G.E.1    Pointaire, P.2    Piguet, P.F.3    Vesin, C.4    Rosen, H.5    Stamenkovic, I.6
  • 50
    • 84896902938 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: positioning cells for host defense and immunity
    • Griffith, J. W., Sokol, C. L., and Luster, A. D. (2014). Chemokines and chemokine receptors: positioning cells for host defense and immunity. Annu. Rev. Immunol. 32, 659–702. doi: 10.1146/annurev-immunol-032713-120145
    • (2014) Annu. Rev. Immunol. , vol.32 , pp. 659-702
    • Griffith, J.W.1    Sokol, C.L.2    Luster, A.D.3
  • 51
    • 79951870968 scopus 로고    scopus 로고
    • Cell biology and immunology of malaria
    • Hafalla, J. C., Silvie, O., and Matuschewski, K. (2011). Cell biology and immunology of malaria. Immunol. Rev. 240, 297–316. doi: 10.1111/j.1600-065X.2010.00988.x
    • (2011) Immunol. Rev. , vol.240 , pp. 297-316
    • Hafalla, J.C.1    Silvie, O.2    Matuschewski, K.3
  • 52
    • 33947356275 scopus 로고    scopus 로고
    • Malaria: mechanisms of erythrocytic infection and pathological correlates of severe disease
    • Haldar, K., Murphy, S. C., Milner, D. A., andTaylor, T. E. (2007). Malaria: mechanisms of erythrocytic infection and pathological correlates of severe disease. Annu. Rev. Pathol. 2, 217–249. doi: 10.1146/annurev.pathol.2.010506.091913
    • (2007) Annu. Rev. Pathol. , vol.2 , pp. 217-249
    • Haldar, K.1    Murphy, S.C.2    Milner, D.A.3    Taylor, T.E.4
  • 53
    • 0024512842 scopus 로고
    • Uninfected erythrocytes form “rosettes” around Plasmodium falciparum infected erythrocytes
    • Handunnetti, S. M., David, P. H., Perera, K. L., and Mendis, K. N. (1989). Uninfected erythrocytes form “rosettes” around Plasmodium falciparum infected erythrocytes. Am. J. Trop. Med. Hyg. 40, 115–118. doi: 10.4269/ajtmh.1989.40.115
    • (1989) Am. J. Trop. Med. Hyg. , vol.40 , pp. 115-118
    • Handunnetti, S.M.1    David, P.H.2    Perera, K.L.3    Mendis, K.N.4
  • 54
    • 34247582292 scopus 로고    scopus 로고
    • NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria
    • Hansen, D. S., Bernard, N. J., Nie, C. Q., and Schofield, L. (2007). NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria. J. Immunol. 178, 5779–5788. doi: 10.4049/jimmunol.178.9.5779
    • (2007) J. Immunol. , vol.178 , pp. 5779-5788
    • Hansen, D.S.1    Bernard, N.J.2    Nie, C.Q.3    Schofield, L.4
  • 55
    • 79958031319 scopus 로고    scopus 로고
    • Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria
    • Haque, A., Best, S. E., Unosson, K., Amante, F. H., De Labastida, F., Anstey, N. M., et al. (2011). Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria. J. Immunol. 186, 6148–6156. doi: 10.4049/jimmunol.1003955
    • (2011) J. Immunol. , vol.186 , pp. 6148-6156
    • Haque, A.1    Best, S.E.2    Unosson, K.3    Amante, F.H.4    De Labastida, F.5    Anstey, N.M.6
  • 56
    • 0038472396 scopus 로고    scopus 로고
    • Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections
    • Hermsen, C. C., Konijnenberg, Y., Mulder, L., Loe, C., Van Deuren, M., Van Der Meer, J. W., et al. (2003). Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections. Clin. Exp. Immunol. 132, 467–472. doi: 10.1046/j.1365-2249.2003.02160.x
    • (2003) Clin. Exp. Immunol. , vol.132 , pp. 467-472
    • Hermsen, C.C.1    Konijnenberg, Y.2    Mulder, L.3    Loe, C.4    Van Deuren, M.5    Van Der Meer, J.W.6
  • 57
    • 77950353500 scopus 로고    scopus 로고
    • The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies
    • Hol, J., Wilhelmsen, L., and Haraldsen, G. (2010). The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies. J. Leukoc. Biol. 87, 501–508. doi: 10.1189/jlb.0809532
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 501-508
    • Hol, J.1    Wilhelmsen, L.2    Haraldsen, G.3
  • 58
    • 84929840773 scopus 로고    scopus 로고
    • Pathogenic CD8+ T cells in experimental cerebral malaria
    • Howland, S. W., Claser, C., Poh, C. M., Gun, S. Y., and Renia, L. (2015). Pathogenic CD8+ T cells in experimental cerebral malaria. Semin. Immunopathol. 37, 221–231. doi: 10.1007/s00281-015-0476-6
    • (2015) Semin. Immunopathol. , vol.37 , pp. 221-231
    • Howland, S.W.1    Claser, C.2    Poh, C.M.3    Gun, S.Y.4    Renia, L.5
  • 59
    • 84936743898 scopus 로고    scopus 로고
    • Activated brain endothelial cells cross-present malaria antigen
    • Howland, S. W., Poh, C. M., and Renia, L. (2015b). Activated brain endothelial cells cross-present malaria antigen. PLoS Pathog. 11:e1004963. doi: 10.1371/journal.ppat.1004963
    • (2015) PLoS Pathog. , vol.11
    • Howland, S.W.1    Poh, C.M.2    Renia, L.3
  • 60
    • 85018634230 scopus 로고    scopus 로고
    • Perforin expression by CD8 T cells Is sufficient to cause fatal brain edema during experimental cerebral malaria
    • Huggins, M. A., Johnson, H. L., Jin, F., N'Songo A., Hanson, L. M., Lafrance, S. J., et al. (2017). Perforin expression by CD8 T cells Is sufficient to cause fatal brain edema during experimental cerebral malaria. Infect. Immun. 85, e00985–e00916. doi: 10.1128/IAI.00985-16
    • (2017) Infect. Immun. , vol.85
    • Huggins, M.A.1    Johnson, H.L.2    Jin, F.3    N'Songo, A.4    Hanson, L.M.5    Lafrance, S.J.6
  • 62
    • 0041378119 scopus 로고    scopus 로고
    • Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria
    • Hunt, N. H., and Grau, G. E. (2003). Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria. Trends Immunol. 24, 491–499. doi: 10.1016/S1471-4906(03)00229-1
    • (2003) Trends Immunol. , vol.24 , pp. 491-499
    • Hunt, N.H.1    Grau, G.E.2
  • 63
    • 77957288323 scopus 로고    scopus 로고
    • Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome
    • Idro, R., Marsh, K., John, C. C., and Newton, C. R. (2010). Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome. Pediatr. Res. 68, 267–274. doi: 10.1203/PDR.0b013e3181eee738
    • (2010) Pediatr. Res. , vol.68 , pp. 267-274
    • Idro, R.1    Marsh, K.2    John, C.C.3    Newton, C.R.4
  • 64
    • 84909606595 scopus 로고    scopus 로고
    • The role of chemokines in severe malaria: more than meets the eye
    • Ioannidis, L. J., Nie, C. Q., and Hansen, D. S. (2014). The role of chemokines in severe malaria: more than meets the eye. Parasitology 141, 602–613. doi: 10.1017/S0031182013001984
    • (2014) Parasitology , vol.141 , pp. 602-613
    • Ioannidis, L.J.1    Nie, C.Q.2    Hansen, D.S.3
  • 65
    • 84957621569 scopus 로고    scopus 로고
    • Monocyte- and neutrophil-derived CXCL10 impairs efficient control of blood-stage malaria infection and promotes severe disease
    • Ioannidis, L. J., Nie, C. Q., Ly, A., Ryg-Cornejo, V., Chiu, C. Y., and Hansen, D. S. (2016). Monocyte- and neutrophil-derived CXCL10 impairs efficient control of blood-stage malaria infection and promotes severe disease. J. Immunol. 196, 1227–1238. doi: 10.4049/jimmunol.1501562
    • (2016) J. Immunol. , vol.196 , pp. 1227-1238
    • Ioannidis, L.J.1    Nie, C.Q.2    Ly, A.3    Ryg-Cornejo, V.4    Chiu, C.Y.5    Hansen, D.S.6
  • 66
    • 44449105631 scopus 로고    scopus 로고
    • Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India
    • Jain, V., Armah, H. B., Tongren, J. E., Ned, R. M., Wilson, N. O., Crawford, S., et al. (2008). Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar. J. 7:83. doi: 10.1186/1475-2875-7-83
    • (2008) Malar. J. , vol.7
    • Jain, V.1    Armah, H.B.2    Tongren, J.E.3    Ned, R.M.4    Wilson, N.O.5    Crawford, S.6
  • 67
    • 77957660950 scopus 로고    scopus 로고
    • Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions
    • Jambou, R., Combes, V., Jambou, M. J., Weksler, B. B., Couraud, P. O., and Grau, G. E. (2010). Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions. PLoS Pathog. 6:e1001021. doi: 10.1371/journal.ppat.1001021
    • (2010) PLoS Pathog. , vol.6
    • Jambou, R.1    Combes, V.2    Jambou, M.J.3    Weksler, B.B.4    Couraud, P.O.5    Grau, G.E.6
  • 68
    • 48249115186 scopus 로고    scopus 로고
    • Cerebral malaria in children is associated with long-term cognitive impairment
    • John, C. C., Bangirana, P., Byarugaba, J., Opoka, R. O., Idro, R., Jurek, A. M., et al. (2008). Cerebral malaria in children is associated with long-term cognitive impairment. Pediatrics 122, e92–e99. doi: 10.1542/peds.2007-3709
    • (2008) Pediatrics , vol.122 , pp. e92-e99
    • John, C.C.1    Bangirana, P.2    Byarugaba, J.3    Opoka, R.O.4    Idro, R.5    Jurek, A.M.6
  • 70
    • 84892552656 scopus 로고    scopus 로고
    • Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria
    • Kalantari, P., Deoliveira, R. B., Chan, J., Corbett, Y., Rathinam, V., Stutz, A., et al. (2014). Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria. Cell Rep. 6, 196–210. doi: 10.1016/j.celrep.2013.12.014
    • (2014) Cell Rep. , vol.6 , pp. 196-210
    • Kalantari, P.1    Deoliveira, R.B.2    Chan, J.3    Corbett, Y.4    Rathinam, V.5    Stutz, A.6
  • 71
    • 84949556667 scopus 로고    scopus 로고
    • The role of chemokines in shaping the balance between CD4(+) T cell subsets and its therapeutic implications in autoimmune and cancer diseases
    • Karin, N., and Wildbaum, G. (2015). The role of chemokines in shaping the balance between CD4(+) T cell subsets and its therapeutic implications in autoimmune and cancer diseases. Front. Immunol. 6:609. doi: 10.3389/fimmu.2015.00609
    • (2015) Front. Immunol. , vol.6
    • Karin, N.1    Wildbaum, G.2
  • 72
    • 0026523620 scopus 로고
    • Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria
    • Karunaweera, N. D., Grau, G. E., Gamage, P., Carter, R., and Mendis, K. N. (1992). Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria. Proc. Natl. Acad. Sci. U.S.A. 89, 3200–3203. doi: 10.1073/pnas.89.8.3200
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 3200-3203
    • Karunaweera, N.D.1    Grau, G.E.2    Gamage, P.3    Carter, R.4    Mendis, K.N.5
  • 73
    • 59649087912 scopus 로고    scopus 로고
    • Severe Plasmodium vivax malaria: a report on serial cases from Bikaner in northwestern India
    • Kochar, D. K., Das, A., Kochar, S. K., Saxena, V., Sirohi, P., Garg, S., et al. (2009). Severe Plasmodium vivax malaria: a report on serial cases from Bikaner in northwestern India. Am. J. Trop. Med. Hyg. 80, 194–198. doi: 10.3410/f.1161230.621714
    • (2009) Am. J. Trop. Med. Hyg. , vol.80 , pp. 194-198
    • Kochar, D.K.1    Das, A.2    Kochar, S.K.3    Saxena, V.4    Sirohi, P.5    Garg, S.6
  • 74
    • 80052341059 scopus 로고    scopus 로고
    • Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria
    • Kordes, M., Matuschewski, K., and Hafalla, J.C. (2011). Caspase-1 activation of interleukin-1beta (IL-1beta) and IL-18 is dispensable for induction of experimental cerebral malaria. Infect. Immun. 79, 3633–3641. doi: 10.1128/IAI.05459-11
    • (2011) Infect. Immun. , vol.79 , pp. 3633-3641
    • Kordes, M.1    Matuschewski, K.2    Hafalla, J.C.3
  • 75
    • 14844337835 scopus 로고    scopus 로고
    • Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity
    • Krishnegowda, G., Hajjar, A. M., Zhu, J., Douglass, E. J., Uematsu, S., Akira, S., et al. (2005). Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity. J. Biol. Chem. 280, 8606–8616. doi: 10.1074/jbc.M413541200
    • (2005) J. Biol. Chem. , vol.280 , pp. 8606-8616
    • Krishnegowda, G.1    Hajjar, A.M.2    Zhu, J.3    Douglass, E.J.4    Uematsu, S.5    Akira, S.6
  • 77
    • 0025015479 scopus 로고
    • TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria
    • Kwiatkowski, D., Hill, A. V., Sambou, I., Twumasi, P., Castracane, J., Manogue, K. R., et al. (1990). TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 336, 1201–1204. doi: 10.1016/0140-6736(90)92827-5
    • (1990) Lancet , vol.336 , pp. 1201-1204
    • Kwiatkowski, D.1    Hill, A.V.2    Sambou, I.3    Twumasi, P.4    Castracane, J.5    Manogue, K.R.6
  • 78
    • 45549097494 scopus 로고    scopus 로고
    • Immunity to malaria: more questions than answers
    • Langhorne, J., Ndungu, F. M., Sponaas, A. M., and Marsh, K. (2008). Immunity to malaria: more questions than answers. Nat. Immunol. 9, 725–732. doi: 10.1038/ni.f.205
    • (2008) Nat. Immunol. , vol.9 , pp. 725-732
    • Langhorne, J.1    Ndungu, F.M.2    Sponaas, A.M.3    Marsh, K.4
  • 79
    • 85014755683 scopus 로고    scopus 로고
    • Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
    • Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., et al. (2017). Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria. Cell Host Microbe 21, 403–414. doi: 10.1016/j.chom.2017.02.009
    • (2017) Cell Host Microbe , vol.21 , pp. 403-414
    • Lennartz, F.1    Adams, Y.2    Bengtsson, A.3    Olsen, R.W.4    Turner, L.5    Ndam, N.T.6
  • 81
    • 84861714135 scopus 로고    scopus 로고
    • Innate recognition of malarial parasites by mammalian hosts
    • Liehl, P., and Mota, M. M. (2012). Innate recognition of malarial parasites by mammalian hosts. Int. J. Parasitol. 42, 557–566. doi: 10.1016/j.ijpara.2012.04.006
    • (2012) Int. J. Parasitol. , vol.42 , pp. 557-566
    • Liehl, P.1    Mota, M.M.2
  • 82
    • 84891874162 scopus 로고    scopus 로고
    • Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
    • Liehl, P., Zuzarte-Luis, V., Chan, J., Zillinger, T., Baptista, F., Carapau, D., et al. (2014). Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nat. Med. 20, 47–53. doi: 10.1038/nm.3424
    • (2014) Nat. Med. , vol.20 , pp. 47-53
    • Liehl, P.1    Zuzarte-Luis, V.2    Chan, J.3    Zillinger, T.4    Baptista, F.5    Carapau, D.6
  • 83
    • 84901850807 scopus 로고    scopus 로고
    • MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation
    • Lopez-Ramirez, M. A., Wu, D., Pryce, G., Simpson, J. E., Reijerkerk, A., King-Robson, J., et al. (2014). MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation. FASEB J. 28, 2551–2565. doi: 10.1096/fj.13-248880
    • (2014) FASEB J. , vol.28 , pp. 2551-2565
    • Lopez-Ramirez, M.A.1    Wu, D.2    Pryce, G.3    Simpson, J.E.4    Reijerkerk, A.5    King-Robson, J.6
  • 84
    • 15644382222 scopus 로고    scopus 로고
    • Crucial role of tumor necrosis factor.(TNF) receptor 2 and membranebound TNF in experimental cerebral malaria
    • Lucas, R., Juillard, P., Decoster, E., Redard, M., Burger, D., Donati, Y., et al. (1997). Crucial role of tumor necrosis factor.(TNF) receptor 2 and membranebound TNF in experimental cerebral malaria. Eur. J. Immunol. 27, 1719–1725. doi: 10.1002/eji.1830270719
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1719-1725
    • Lucas, R.1    Juillard, P.2    Decoster, E.3    Redard, M.4    Burger, D.5    Donati, Y.6
  • 85
    • 84882329201 scopus 로고    scopus 로고
    • An evolving new paradigm: endothelial cells–conditional innate immune cells
    • Mai, J., Virtue, A., Shen, J., Wang, H., and Yang, X. F. (2013). An evolving new paradigm: endothelial cells–conditional innate immune cells. J. Hematol. Oncol. 6:61. doi: 10.1186/1756-8722-6-61
    • (2013) J. Hematol. Oncol. , vol.6
    • Mai, J.1    Virtue, A.2    Shen, J.3    Wang, H.4    Yang, X.F.5
  • 86
    • 85017569163 scopus 로고    scopus 로고
    • Cytokine profiles in Malawian children presenting with uncomplicated malaria, severe malarial anemia and cerebral malaria
    • Mandala, W. L., Msefula, C. L., Gondwe, E. N., Drayson, M. T., Molyneux, M. E., and Maclennan, C. A. (2017). Cytokine profiles in Malawian children presenting with uncomplicated malaria, severe malarial anemia and cerebral malaria. Clin. Vaccine Immunol. 24:e00533-16. doi: 10.1128/CVI.00533-16
    • (2017) Clin. Vaccine Immunol. , vol.24 , pp. e00533-e00516
    • Mandala, W.L.1    Msefula, C.L.2    Gondwe, E.N.3    Drayson, M.T.4    Molyneux, M.E.5    Maclennan, C.A.6
  • 87
    • 84992360055 scopus 로고    scopus 로고
    • Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria
    • Mantel, P. Y., Hjelmqvist, D., Walch, M., Kharoubi-Hess, S., Nilsson, S., Ravel, D., et al. (2016). Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria. Nat. Commun. 7:12727. doi: 10.1038/ncomms12727
    • (2016) Nat. Commun. , vol.7
    • Mantel, P.Y.1    Hjelmqvist, D.2    Walch, M.3    Kharoubi-Hess, S.4    Nilsson, S.5    Ravel, D.6
  • 88
    • 84877855333 scopus 로고    scopus 로고
    • Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system
    • Mantel, P. Y., Hoang, A. N., Goldowitz, I., Potashnikova, D., Hamza, B., Vorobjev, I., et al. (2013). Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe 13, 521–534. doi: 10.1016/j.chom.2013.04.009
    • (2013) Cell Host Microbe , vol.13 , pp. 521-534
    • Mantel, P.Y.1    Hoang, A.N.2    Goldowitz, I.3    Potashnikova, D.4    Hamza, B.5    Vorobjev, I.6
  • 89
    • 0021592646 scopus 로고
    • Evolutionary relatedness of Plasmodium species as determined by the structure of DNA
    • McCutchan, T. F., Dame, J. B., Miller, L. H., and Barnwell, J. (1984). Evolutionary relatedness of Plasmodium species as determined by the structure of DNA. Science 225, 808–811. doi: 10.1126/science.6382604
    • (1984) Science , vol.225 , pp. 808-811
    • McCutchan, T.F.1    Dame, J.B.2    Miller, L.H.3    Barnwell, J.4
  • 90
    • 0034330847 scopus 로고    scopus 로고
    • Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparumparasitized erythrocytes: a role for CD36 in malarial clearance
    • McGilvray, I. D., Serghides, L., Kapus, A., Rotstein, O. D., and Kain, K. C. (2000). Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparumparasitized erythrocytes: a role for CD36 in malarial clearance. Blood 96, 3231–3240. Available online at: http://www.bloodjournal.org/content/96/9/3231
    • (2000) Blood , vol.96 , pp. 3231-3240
    • McGilvray, I.D.1    Serghides, L.2    Kapus, A.3    Rotstein, O.D.4    Kain, K.C.5
  • 91
    • 0035070574 scopus 로고    scopus 로고
    • Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology
    • Medana, I. M., Chaudhri, G., Chan-Ling, T., and Hunt, N. H. (2001). Central nervous system in cerebral malaria: 'Innocent bystander' or active participant in the induction of immunopathology? Immunol. Cell Biol. 79, 101–120. doi: 10.1046/j.1440-1711.2001.00995.x
    • (2001) Immunol. Cell Biol. , vol.79 , pp. 101-120
    • Medana, I.M.1    Chaudhri, G.2    Chan-Ling, T.3    Hunt, N.H.4
  • 92
    • 33646337645 scopus 로고    scopus 로고
    • Human cerebral malaria and the blood-brain barrier
    • Medana, I. M., and Turner, G. D. (2006). Human cerebral malaria and the blood-brain barrier. Int. J. Parasitol. 36, 555–568. doi: 10.1016/j.ijpara.2006.02.004
    • (2006) Int. J. Parasitol. , vol.36 , pp. 555-568
    • Medana, I.M.1    Turner, G.D.2
  • 93
    • 33947421712 scopus 로고    scopus 로고
    • Plasmodium falciparum and the blood-brain barrier–contacts and consequences
    • Medana, I. M., and Turner, G. D. (2007). Plasmodium falciparum and the blood-brain barrier–contacts and consequences. J. Infect. Dis. 195, 921–923. doi: 10.1086/512089
    • (2007) J. Infect. Dis. , vol.195 , pp. 921-923
    • Medana, I.M.1    Turner, G.D.2
  • 94
    • 84899626405 scopus 로고    scopus 로고
    • Interferon-mediated innate immune responses against malaria parasite liver stages
    • Miller, J. L., Sack, B. K., Baldwin, M., Vaughan, A. M., and Kappe, S. H. (2014). Interferon-mediated innate immune responses against malaria parasite liver stages. Cell Rep. 7, 436–447. doi: 10.1016/j.celrep.2014.03.018
    • (2014) Cell Rep. , vol.7 , pp. 436-447
    • Miller, J.L.1    Sack, B.K.2    Baldwin, M.3    Vaughan, A.M.4    Kappe, S.H.5
  • 95
    • 0037034017 scopus 로고    scopus 로고
    • The pathogenic basis of malaria
    • Miller, L. H., Baruch, D. I., Marsh, K., and Doumbo, O. K. (2002). The pathogenic basis of malaria. Nature 415, 673–679. doi: 10.1038/415673a
    • (2002) Nature , vol.415 , pp. 673-679
    • Miller, L.H.1    Baruch, D.I.2    Marsh, K.3    Doumbo, O.K.4
  • 96
    • 84943416408 scopus 로고    scopus 로고
    • Quantitative assessment of multiorgan sequestration of parasites in fatal pediatric cerebral malaria
    • Milner, D. A. Jr., Lee, J. J., Frantzreb, C., Whitten, R. O., Kamiza, S., Carr, R. A., et al. (2015). Quantitative assessment of multiorgan sequestration of parasites in fatal pediatric cerebral malaria. J. Infect. Dis. 212, 1317–1321. doi: 10.1093/infdis/jiv205
    • (2015) J. Infect. Dis. , vol.212 , pp. 1317-1321
    • Milner, D.A.1    Lee, J.J.2    Frantzreb, C.3    Whitten, R.O.4    Kamiza, S.5    Carr, R.A.6
  • 98
    • 40449101327 scopus 로고    scopus 로고
    • Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency
    • Miu, J., Mitchell, A. J., Muller, M., Carter, S. L., Manders, P. M., Mcquillan, J. A., et al. (2008). Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J. Immunol. 180, 1217–1230. doi: 10.4049/jimmunol.180.2.1217
    • (2008) J. Immunol. , vol.180 , pp. 1217-1230
    • Miu, J.1    Mitchell, A.J.2    Muller, M.3    Carter, S.L.4    Manders, P.M.5    Mcquillan, J.A.6
  • 100
    • 66349084437 scopus 로고    scopus 로고
    • IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection
    • Nie, C. Q., Bernard, N. J., Norman, M. U., Amante, F. H., Lundie, R. J., Crabb, B. S., et al. (2009). IP-10-mediated T cell homing promotes cerebral inflammation over splenic immunity to malaria infection. PLoS Pathog. :e1000369. doi: 10.1371/journal.ppat.1000369
    • (2009) PLoS Pathog.
    • Nie, C.Q.1    Bernard, N.J.2    Norman, M.U.3    Amante, F.H.4    Lundie, R.J.5    Crabb, B.S.6
  • 102
    • 84889872057 scopus 로고    scopus 로고
    • Development, maintenance and disruption of the blood-brain barrier
    • Obermeier, B., Daneman, R., andRansohoff, R. M. (2013). Development, maintenance and disruption of the blood-brain barrier. Nat. Med. 19, 1584–1596. doi: 10.1038/nm.3407
    • (2013) Nat. Med. , vol.19 , pp. 1584-1596
    • Obermeier, B.1    Daneman, R.2    Ransohoff, R.M.3
  • 104
    • 84976509278 scopus 로고    scopus 로고
    • Seven-Year efficacy of RTS,S/AS01 malaria vaccine among young African children
    • Olotu, A., Fegan, G., Wambua, J., Nyangweso, G., Leach, A., Lievens, M., et al. (2016). Seven-Year efficacy of RTS,S/AS01 malaria vaccine among young African children. N. Engl. J. Med. 374, 2519–2529. doi: 10.1056/NEJMoa1515257
    • (2016) N. Engl. J. Med. , vol.374 , pp. 2519-2529
    • Olotu, A.1    Fegan, G.2    Wambua, J.3    Nyangweso, G.4    Leach, A.5    Lievens, M.6
  • 105
    • 0035852652 scopus 로고    scopus 로고
    • Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria
    • Pain, A., Ferguson, D. J., Kai, O., Urban, B. C., Lowe, B., Marsh, K., et al. (2001). Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria. Proc. Natl. Acad. Sci. U.S.A. 98, 1805–1810. doi: 10.1073/pnas.98.4.1805
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 1805-1810
    • Pain, A.1    Ferguson, D.J.2    Kai, O.3    Urban, B.C.4    Lowe, B.5    Marsh, K.6
  • 106
    • 84885735527 scopus 로고    scopus 로고
    • Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA
    • Palomo, J., Fauconnier, M., Coquard, L., Gilles, M., Meme, S., Szeremeta, F., et al. (2013). Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA. Eur. J. Immunol. 43, 2683–2695. doi: 10.1002/eji.201343327
    • (2013) Eur. J. Immunol. , vol.43 , pp. 2683-2695
    • Palomo, J.1    Fauconnier, M.2    Coquard, L.3    Gilles, M.4    Meme, S.5    Szeremeta, F.6
  • 107
    • 33846911691 scopus 로고    scopus 로고
    • Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9
    • Parroche, P., Lauw, F. N., Goutagny, N., Latz, E., Monks, B. G., Visintin, A., et al. (2007). Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9. Proc. Natl. Acad. Sci. U.S.A. 104, 1919–1924. doi: 10.1073/pnas.0608745104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 1919-1924
    • Parroche, P.1    Lauw, F.N.2    Goutagny, N.3    Latz, E.4    Monks, B.G.5    Visintin, A.6
  • 108
    • 0028342953 scopus 로고
    • Malaria, the red cell, and the endothelium
    • Pasloske, B. L., and Howard, R. J. (1994). Malaria, the red cell, and the endothelium. Annu. Rev. Med. 45, 283–295. doi: 10.1146/annurev.med.45.1.283
    • (1994) Annu. Rev. Med. , vol.45 , pp. 283-295
    • Pasloske, B.L.1    Howard, R.J.2
  • 109
    • 0025304016 scopus 로고
    • Cytokines and endothelial cell biology
    • Pober, J. S., and Cotran, R. S. (1990). Cytokines and endothelial cell biology. Physiol. Rev. 70, 427–451.
    • (1990) Physiol. Rev. , vol.70 , pp. 427-451
    • Pober, J.S.1    Cotran, R.S.2
  • 110
    • 34748914299 scopus 로고    scopus 로고
    • Evolving functions of endothelial cells in inflammation
    • Pober, J. S., and Sessa, W. C. (2007). Evolving functions of endothelial cells in inflammation. Nat. Rev. Immunol. 7, 803–815. doi: 10.1038/nri2171
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 803-815
    • Pober, J.S.1    Sessa, W.C.2
  • 111
    • 84863063544 scopus 로고    scopus 로고
    • Sequestration and microvascular congestion are associated with coma in human cerebral malaria
    • Ponsford, M. J., Medana, I. M., Prapansilp, P., Hien, T. T., Lee, S. J., Dondorp, A. M., et al. (2012). Sequestration and microvascular congestion are associated with coma in human cerebral malaria. J. Infect. Dis. 205, 663–671. doi: 10.1093/infdis/jir812
    • (2012) J. Infect. Dis. , vol.205 , pp. 663-671
    • Ponsford, M.J.1    Medana, I.M.2    Prapansilp, P.3    Hien, T.T.4    Lee, S.J.5    Dondorp, A.M.6
  • 112
    • 33746128777 scopus 로고    scopus 로고
    • Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of central India
    • Prakash, D., Fesel, C., Jain, R., Cazenave, P. A., Mishra, G. C., and Pied, S. (2006). Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of central India. J. Infect. Dis. 194, 198–207. doi: 10.1086/504720
    • (2006) J. Infect. Dis. , vol.194 , pp. 198-207
    • Prakash, D.1    Fesel, C.2    Jain, R.3    Cazenave, P.A.4    Mishra, G.C.5    Pied, S.6
  • 115
    • 70349311420 scopus 로고    scopus 로고
    • Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications
    • Rowe, J. A., Claessens, A., Corrigan, R. A., and Arman, M. (2009). Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications. Expert Rev. Mol. Med. 11:e16. doi: 10.1017/S1462399409001082
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Rowe, J.A.1    Claessens, A.2    Corrigan, R.A.3    Arman, M.4
  • 117
    • 84877014666 scopus 로고    scopus 로고
    • Association of TNF level with production of circulating cellular microparticles during clinical manifestation of human cerebral malaria
    • Sahu, U., Sahoo, P. K., Kar, S. K., Mohapatra, B. N., and Ranjit, M. (2013). Association of TNF level with production of circulating cellular microparticles during clinical manifestation of human cerebral malaria. Hum. Immunol. 74, 713–721. doi: 10.1016/j.humimm.2013.02.006
    • (2013) Hum. Immunol. , vol.74 , pp. 713-721
    • Sahu, U.1    Sahoo, P.K.2    Kar, S.K.3    Mohapatra, B.N.4    Ranjit, M.5
  • 118
    • 25444475850 scopus 로고    scopus 로고
    • Immunological processes in malaria pathogenesis
    • Schofield, L., and Grau, G. E. (2005). Immunological processes in malaria pathogenesis. Nat. Rev. Immunol. 5, 722–735. doi: 10.1038/nri1686
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 722-735
    • Schofield, L.1    Grau, G.E.2
  • 119
    • 0027471132 scopus 로고
    • Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites
    • Schofield, L., and Hackett, F. (1993). Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites. J. Exp. Med. 177, 145–153. doi: 10.1084/jem.177.1.145
    • (1993) J. Exp. Med. , vol.177 , pp. 145-153
    • Schofield, L.1    Hackett, F.2
  • 120
    • 85019677538 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria
    • Shabani, E., Ouma, B. J., Idro, R., Bangirana, P., Opoka, R. O., Park, G. S., et al. (2017). Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria. Parasite Immunol. 39:e12438. doi: 10.1111/pim.12438
    • (2017) Parasite Immunol. , vol.39
    • Shabani, E.1    Ouma, B.J.2    Idro, R.3    Bangirana, P.4    Opoka, R.O.5    Park, G.S.6
  • 121
    • 80051880722 scopus 로고    scopus 로고
    • Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome
    • Sharma, S., Deoliveira, R. B., Kalantari, P., Parroche, P., Goutagny, N., Jiang, Z., et al. (2011). Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity 35, 194–207. doi: 10.1016/j.immuni.2011.05.016
    • (2011) Immunity , vol.35 , pp. 194-207
    • Sharma, S.1    Deoliveira, R.B.2    Kalantari, P.3    Parroche, P.4    Goutagny, N.5    Jiang, Z.6
  • 122
    • 84990173825 scopus 로고    scopus 로고
    • Uptake of parasite-derived vesicles by astrocytes and microglial phagocytosis of infected erythrocytes may drive neuroinflammation in cerebral malaria
    • Shrivastava, S. K., Dalko, E., Delcroix-Genete, D., Herbert, F., Cazenave, P. A., and Pied, S. (2017). Uptake of parasite-derived vesicles by astrocytes and microglial phagocytosis of infected erythrocytes may drive neuroinflammation in cerebral malaria. Glia 65, 75–92. doi: 10.1002/glia.23075
    • (2017) Glia , vol.65 , pp. 75-92
    • Shrivastava, S.K.1    Dalko, E.2    Delcroix-Genete, D.3    Herbert, F.4    Cazenave, P.A.5    Pied, S.6
  • 123
    • 84907567820 scopus 로고    scopus 로고
    • The peculiarities and paradoxes of Plasmodium heme metabolism
    • Sigala, P. A., and Goldberg, D. E. (2014). The peculiarities and paradoxes of Plasmodium heme metabolism. Annu. Rev. Microbiol. 68, 259–278. doi: 10.1146/annurev-micro-091313-103537
    • (2014) Annu. Rev. Microbiol. , vol.68 , pp. 259-278
    • Sigala, P.A.1    Goldberg, D.E.2
  • 124
    • 84887615340 scopus 로고    scopus 로고
    • Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes
    • Smith, J. D., Rowe, J. A., Higgins, M. K., and Lavstsen, T. (2013). Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes. Cell. Microbiol. 15, 1976–1983. doi: 10.1111/cmi.12183
    • (2013) Cell. Microbiol. , vol.15 , pp. 1976-1983
    • Smith, J.D.1    Rowe, J.A.2    Higgins, M.K.3    Lavstsen, T.4
  • 125
    • 0347989376 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells
    • Song, L., and Pachter, J. S. (2004). Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells. Microvasc. Res. 67, 78–89. doi: 10.1016/j.mvr.2003.07.001
    • (2004) Microvasc. Res. , vol.67 , pp. 78-89
    • Song, L.1    Pachter, J.S.2
  • 127
    • 0344465840 scopus 로고    scopus 로고
    • Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase
    • Stamatovic, S. M., Keep, R. F., Kunkel, S. L., and Andjelkovic, A. V. (2003). Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J. Cell Sci. 116, 4615–4628. doi: 10.1242/jcs.00755
    • (2003) J. Cell Sci. , vol.116 , pp. 4615-4628
    • Stamatovic, S.M.1    Keep, R.F.2    Kunkel, S.L.3    Andjelkovic, A.V.4
  • 128
    • 1542720941 scopus 로고    scopus 로고
    • Innate immunity to malaria
    • Stevenson, M. M., and Riley, E. M. (2004). Innate immunity to malaria. Nat. Rev. Immunol. 4, 169–180. doi: 10.1038/nri1311
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 169-180
    • Stevenson, M.M.1    Riley, E.M.2
  • 129
    • 84987985154 scopus 로고    scopus 로고
    • Pathogenesis of cerebral malaria– inflammation and cytoadherence
    • Storm, J., and Craig, A. G. (2014). Pathogenesis of cerebral malaria– inflammation and cytoadherence. Front. Cell. Infect. Microbiol. 4:100. doi: 10.3389/fcimb.2014.00100
    • (2014) Front. Cell. Infect. Microbiol. , vol.4
    • Storm, J.1    Craig, A.G.2
  • 130
    • 0346949034 scopus 로고    scopus 로고
    • Regulation of the kinetics of intracerebral chemokine gene expression in murine Toxoplasma encephalitis: impact of host genetic factors
    • Strack, A., Schlüter, D., Asensio, V.C., Campbell, I. L., and Deckert, M. (2002). Regulation of the kinetics of intracerebral chemokine gene expression in murine Toxoplasma encephalitis: impact of host genetic factors. Glia 40, 372–377. doi: 10.1002/glia.10104
    • (2002) Glia , vol.40 , pp. 372-377
    • Strack, A.1    Schlüter, D.2    Asensio, V.C.3    Campbell, I.L.4    Deckert, M.5
  • 131
    • 0030042523 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway
    • Tachado, S. D., Gerold, P., Mcconville, M. J., Baldwin, T., Quilici, D., Schwarz, R. T., et al. (1996). Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway. J. Immunol. 156, 1897–1907.
    • (1996) J. Immunol. , vol.156 , pp. 1897-1907
    • Tachado, S.D.1    Gerold, P.2    Mcconville, M.J.3    Baldwin, T.4    Quilici, D.5    Schwarz, R.T.6
  • 132
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O., and Akira, S. (2010). Pattern recognition receptors and inflammation. Cell 140, 805–820. doi: 10.1016/j.cell.2010.01.022
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 133
    • 34249701886 scopus 로고    scopus 로고
    • Severe malaria in Cameroonian children: correlation between plasma levels of three soluble inducible adhesion molecules and TNF-alpha
    • Tchinda, V. H., Tadem, A. D., Tako, E. A., Tene, G., Fogako, J., Nyonglema, P., et al. (2007). Severe malaria in Cameroonian children: correlation between plasma levels of three soluble inducible adhesion molecules and TNF-alpha. Acta Trop. 102, 20–28. doi: 10.1016/j.actatropica.2007.02.011
    • (2007) Acta Trop. , vol.102 , pp. 20-28
    • Tchinda, V.H.1    Tadem, A.D.2    Tako, E.A.3    Tene, G.4    Fogako, J.5    Nyonglema, P.6
  • 134
    • 79851506686 scopus 로고    scopus 로고
    • Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia
    • Thuma, P. E., Van Dijk, J., Bucala, R., Debebe, Z., Nekhai, S., Kuddo, T., et al. (2011). Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia. J. Infect. Dis. 203, 211–219. doi: 10.1093/infdis/jiq041
    • (2011) J. Infect. Dis. , vol.203 , pp. 211-219
    • Thuma, P.E.1    Van Dijk, J.2    Bucala, R.3    Debebe, Z.4    Nekhai, S.5    Kuddo, T.6
  • 135
    • 85002718315 scopus 로고    scopus 로고
    • Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content
    • Tiberti, N., Latham, S. L., Bush, S., Cohen, A., Opoka, R. O., John, C. C., et al. (2016). Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content. Sci. Rep. 6:37871. doi: 10.1038/srep37871
    • (2016) Sci. Rep. , vol.6
    • Tiberti, N.1    Latham, S.L.2    Bush, S.3    Cohen, A.4    Opoka, R.O.5    John, C.C.6
  • 136
    • 34250866255 scopus 로고    scopus 로고
    • Murine cerebral malaria development is independent of toll-like receptor signaling
    • Togbe, D., Schofield, L., Grau, G. E., Schnyder, B., Boissay, V., Charron, S., et al. (2007). Murine cerebral malaria development is independent of toll-like receptor signaling. Am. J. Pathol. 170, 1640–1648. doi: 10.2353/ajpath.2007.060889
    • (2007) Am. J. Pathol. , vol.170 , pp. 1640-1648
    • Togbe, D.1    Schofield, L.2    Grau, G.E.3    Schnyder, B.4    Boissay, V.5    Charron, S.6
  • 137
    • 77950530988 scopus 로고    scopus 로고
    • Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium
    • Tripathi, A. K., Sha, W., Shulaev, V., Stins, M. F., and Sullivan, D. J. Jr., (2009). Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium. Blood 114, 4243–4252. doi: 10.1182/blood-2009-06-226415
    • (2009) Blood , vol.114 , pp. 4243-4252
    • Tripathi, A.K.1    Sha, W.2    Shulaev, V.3    Stins, M.F.4    Sullivan, D.J.J.5
  • 138
    • 33646947271 scopus 로고    scopus 로고
    • Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB
    • Tripathi, A. K., Sullivan, D. J., and Stins, M. F. (2006). Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB. Infect. Immun. 74, 3262–3270. doi: 10.1128/IAI.01625-05
    • (2006) Infect. Immun. , vol.74 , pp. 3262-3270
    • Tripathi, A.K.1    Sullivan, D.J.2    Stins, M.F.3
  • 139
    • 33947428432 scopus 로고    scopus 로고
    • Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers
    • Tripathi, A. K., Sullivan, D. J., and Stins, M. F. (2007). Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers. J. Infect. Dis. 195, 942–950. doi: 10.1086/512083
    • (2007) J. Infect. Dis. , vol.195 , pp. 942-950
    • Tripathi, A.K.1    Sullivan, D.J.2    Stins, M.F.3
  • 140
    • 2642644550 scopus 로고    scopus 로고
    • Systemic endothelial activation occurs in both mild and severe malaria. Correlating dermal microvascular endothelial cell phenotype and soluble cell adhesion molecules with disease severity
    • Turner, G. D., Ly, V. C., Nguyen, T. H., Tran, T. H., Nguyen, H. P., Bethell, D., et al. (1998). Systemic endothelial activation occurs in both mild and severe malaria. Correlating dermal microvascular endothelial cell phenotype and soluble cell adhesion molecules with disease severity. Am. J. Pathol. 152, 1477–1487.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1477-1487
    • Turner, G.D.1    Ly, V.C.2    Nguyen, T.H.3    Tran, T.H.4    Nguyen, H.P.5    Bethell, D.6
  • 141
    • 0028046041 scopus 로고
    • An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration
    • Turner, G. D., Morrison, H., Jones, M., Davis, T. M., Looareesuwan, S., Buley, I. D., et al. (1994). An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. Am. J. Pathol. 145, 1057–1069.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1057-1069
    • Turner, G.D.1    Morrison, H.2    Jones, M.3    Davis, T.M.4    Looareesuwan, S.5    Buley, I.D.6
  • 142
    • 84879691819 scopus 로고    scopus 로고
    • Severe malaria is associated with parasite binding to endothelial protein C receptor
    • Turner, L., Lavstsen, T., Berger, S. S., Wang, C. W., Petersen, J. E., Avril, M., et al. (2013). Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature 498, 502–505. doi: 10.1038/nature12216
    • (2013) Nature , vol.498 , pp. 502-505
    • Turner, L.1    Lavstsen, T.2    Berger, S.S.3    Wang, C.W.4    Petersen, J.E.5    Avril, M.6
  • 143
    • 44849129838 scopus 로고    scopus 로고
    • CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines
    • Van den Steen, P. E., Deroost, K., Van Aelst, I., Geurts, N., Martens, E., Struyf, S., et al. (2008). CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines. Eur. J. Immunol. 38, 1082–1095. doi: 10.1002/eji.200737906
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1082-1095
    • Van den Steen, P.E.1    Deroost, K.2    Van Aelst, I.3    Geurts, N.4    Martens, E.5    Struyf, S.6
  • 144
    • 33749266350 scopus 로고    scopus 로고
    • A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction
    • van der Heyde, H. C., Nolan, J., Combes, V., Gramaglia, I., and Grau, G. E. (2006). A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction. Trends Parasitol. 22, 503–508. doi: 10.1016/j.pt.2006.09.002
    • (2006) Trends Parasitol. , vol.22 , pp. 503-508
    • van der Heyde, H.C.1    Nolan, J.2    Combes, V.3    Gramaglia, I.4    Grau, G.E.5
  • 145
    • 19244362897 scopus 로고    scopus 로고
    • The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria
    • van Hensbroek, M. B., Palmer, A., Onyiorah, E., Schneider, G., Jaffar, S., Dolan, G., et al. (1996). The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria. J. Infect. Dis. 174, 1091–1097. doi: 10.1093/infdis/174.5.1091
    • (1996) J. Infect. Dis. , vol.174 , pp. 1091-1097
    • van Hensbroek, M.B.1    Palmer, A.2    Onyiorah, E.3    Schneider, G.4    Jaffar, S.5    Dolan, G.6
  • 146
    • 19744372987 scopus 로고    scopus 로고
    • Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes
    • Viebig, N. K., Wulbrand, U., Forster, R., Andrews, K. T., Lanzer, M., and Knolle, P. A. (2005). Direct activation of human endothelial cells by Plasmodium falciparum-infected erythrocytes. Infect. Immun. 73, 3271–3277. doi: 10.1128/IAI.73.6.3271-3277.2005
    • (2005) Infect. Immun. , vol.73 , pp. 3271-3277
    • Viebig, N.K.1    Wulbrand, U.2    Forster, R.3    Andrews, K.T.4    Lanzer, M.5    Knolle, P.A.6
  • 147
    • 84863621019 scopus 로고    scopus 로고
    • IFN-gamma-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain
    • Villegas-Mendez, A., Greig, R., Shaw, T. N., De Souza, J. B., Gwyer Findlay, E., Stumhofer, J. S., et al. (2012). IFN-gamma-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J. Immunol. 189, 968–979. doi: 10.4049/jimmunol.1200688
    • (2012) J. Immunol. , vol.189 , pp. 968-979
    • Villegas-Mendez, A.1    Greig, R.2    Shaw, T.N.3    De Souza, J.B.4    Gwyer Findlay, E.5    Stumhofer, J.S.6
  • 148
    • 41149111580 scopus 로고    scopus 로고
    • Chemokines and their receptors: drug targets in immunity and inflammation
    • Viola, A., and Luster, A. D. (2008). Chemokines and their receptors: drug targets in immunity and inflammation. Annu. Rev. Pharmacol. Toxicol. 48, 171–197. doi: 10.1146/annurev.pharmtox.48.121806.154841
    • (2008) Annu. Rev. Pharmacol. Toxicol. , vol.48 , pp. 171-197
    • Viola, A.1    Luster, A.D.2
  • 149
    • 84998699267 scopus 로고    scopus 로고
    • Severe malaria: what's new on the pathogenesis front
    • Wassmer, S. C., and Grau, G. E. (2017). Severe malaria: what's new on the pathogenesis front? Int. J. Parasitol. 47, 145–152. doi: 10.1016/j.ijpara.2016.08.002
    • (2017) Int. J. Parasitol. , vol.47 , pp. 145-152
    • Wassmer, S.C.1    Grau, G.E.2
  • 150
    • 78651414899 scopus 로고    scopus 로고
    • Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF
    • Wassmer, S. C., Moxon, C. A., Taylor, T., Grau, G. E., Molyneux, M. E., and Craig, A. G. (2011). Vascular endothelial cells cultured from patients with cerebral or uncomplicated malaria exhibit differential reactivity to TNF. Cell. Microbiol. 13, 198–209. doi: 10.1111/j.1462-5822.2010.01528.x
    • (2011) Cell. Microbiol. , vol.13 , pp. 198-209
    • Wassmer, S.C.1    Moxon, C.A.2    Taylor, T.3    Grau, G.E.4    Molyneux, M.E.5    Craig, A.G.6
  • 151
    • 85012983566 scopus 로고    scopus 로고
    • World Malaria Report 2016
    • Geneva: World Health Organisation
    • WHO (2016). World Malaria Report 2016. Geneva: World Health Organisation.
    • (2016)
  • 152
    • 84951567221 scopus 로고    scopus 로고
    • Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial
    • White, M. T., Verity, R., Griffin, J. T., Asante, K. P., Owusu-Agyei, S., Greenwood, B., et al. (2015). Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. Lancet Infect. Dis. 15, 1450–1458. doi: 10.1016/S1473-3099(15)00239-X
    • (2015) Lancet Infect. Dis. , vol.15 , pp. 1450-1458
    • White, M.T.1    Verity, R.2    Griffin, J.T.3    Asante, K.P.4    Owusu-Agyei, S.5    Greenwood, B.6
  • 153
    • 79955085793 scopus 로고    scopus 로고
    • CXCL4 and CXCL10 predict risk of fatal cerebral malaria
    • Wilson, N. O., Jain, V., Roberts, C. E., Lucchi, N., Joel, P. K., Singh, M. P., et al. (2011). CXCL4 and CXCL10 predict risk of fatal cerebral malaria. Dis. Markers 30, 39–49. doi: 10.1155/2011/828256
    • (2011) Dis. Markers , vol.30 , pp. 39-49
    • Wilson, N.O.1    Jain, V.2    Roberts, C.E.3    Lucchi, N.4    Joel, P.K.5    Singh, M.P.6
  • 154
    • 84942878158 scopus 로고    scopus 로고
    • Phagosomal acidification prevents macrophage inflammatory cytokine production to malaria, and dendritic cells are the major source at the early stages of infection: implication for malaria protective immunity development
    • Wu, X., Gowda, N. M., and Gowda, D. C. (2015). Phagosomal acidification prevents macrophage inflammatory cytokine production to malaria, and dendritic cells are the major source at the early stages of infection: implication for malaria protective immunity development. J. Biol. Chem. 290, 23135–23147. doi: 10.1074/jbc.M115.671065
    • (2015) J. Biol. Chem. , vol.290 , pp. 23135-23147
    • Wu, X.1    Gowda, N.M.2    Gowda, D.C.3
  • 155
    • 0030586620 scopus 로고    scopus 로고
    • Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria
    • Yanez, D. M., Manning, D. D., Cooley, A. J., Weidanz, W. P., and Van Der Heyde, H. C. (1996). Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malaria. J. Immunol. 157, 1620–1624.
    • (1996) J. Immunol. , vol.157 , pp. 1620-1624
    • Yanez, D.M.1    Manning, D.D.2    Cooley, A.J.3    Weidanz, W.P.4    Van Der Heyde, H.C.5
  • 156
    • 79955531506 scopus 로고    scopus 로고
    • Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption
    • Yao, Y., and Tsirka, S. E. (2011). Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption. J. Cell Sci. 124, 1486–1495. doi: 10.1242/jcs.082834
    • (2011) J. Cell Sci. , vol.124 , pp. 1486-1495
    • Yao, Y.1    Tsirka, S.E.2
  • 157
    • 79956110876 scopus 로고    scopus 로고
    • Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1
    • Zhu, J., Krishnegowda, G., Li, G., and Gowda, D. C. (2011). Proinflammatory responses by glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1. Exp. Parasitol. 128, 205–211. doi: 10.1016/j.exppara.2011.03.010
    • (2011) Exp. Parasitol. , vol.128 , pp. 205-211
    • Zhu, J.1    Krishnegowda, G.2    Li, G.3    Gowda, D.C.4
  • 158
    • 67650106539 scopus 로고    scopus 로고
    • MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophages
    • Zhu, J., Wu, X., Goel, S., Gowda, N. M., Kumar, S., Krishnegowda, G., et al. (2009). MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophages. J. Biol. Chem. 284, 15750–15761. doi: 10.1074/jbc.M901111200
    • (2009) J. Biol. Chem. , vol.284 , pp. 15750-15761
    • Zhu, J.1    Wu, X.2    Goel, S.3    Gowda, N.M.4    Kumar, S.5    Krishnegowda, G.6
  • 159
    • 84861426163 scopus 로고    scopus 로고
    • The chemokine superfamily revisited
    • Zlotnik, A., and Yoshie, O. (2012). The chemokine superfamily revisited. Immunity 36, 705–716. doi: 10.1016/j.immuni.2012.05.008
    • (2012) Immunity , vol.36 , pp. 705-716
    • Zlotnik, A.1    Yoshie, O.2


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