Participation of Lymphocyte Subpopulations in the Pathogenesis of Experimental Murine Cerebral Malaria

Journal of Immunology

Volumn 157, Issue 4, 1996, Pages 1620-1624

  Yañez, Deborah M ^a   Manning, Dean D ^a   Cooley, Avery J ^a   Weidanz, William P ^a   Van Der Heyde, Henri C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIGEN; BETA 2 MICROGLOBULIN; GAMMA INTERFERON; HLA ANTIGEN CLASS 2; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4;

ANIMAL; ARTICLE; C57BL MOUSE; CD8+ T LYMPHOCYTE; COMBINED IMMUNODEFICIENCY; FEMALE; GENE; GENETICS; GERMFREE ANIMAL; IMMUNE DEFICIENCY; IMMUNOLOGY; INVARIANT CHAIN; LYMPHOCYTE DEPLETION; LYMPHOCYTE SUBPOPULATION; MALARIA; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PLASMODIUM BERGHEI; SECRETION; TH1 CELL; TH2 CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; BETA 2-MICROGLOBULIN; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GENES, MHC CLASS II; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOCOMPROMISED HOST; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE DEPLETION; LYMPHOCYTE SUBSETS; MALARIA, CEREBRAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, SCID; PLASMODIUM BERGHEI; SEVERE COMBINED IMMUNODEFICIENCY; SPECIFIC PATHOGEN-FREE ORGANISMS; TH1 CELLS; TH2 CELLS;

EID: 0030586620     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. World Health Organization. 1994. World malaria situation in 1992, part I. Weekly Epidemiol. Rec. 64:309.
2. Warrell, D. A. 1989. Drugs for prevention and treatment of severe malaria. TDR News 26:6.
3. Greenwood, B. M., A. K. Bradley, A. M. Greenwood, P. Byass, K. Jammeh, K. Marsh, S. Tulloch, F. S. J. Oldfield, and R. Hayes. 1987. Mortality and morbidity from malaria among children in rural area of the Gambia, West Africa. Trans. R. Soc. Trop. Med. Hyg. 81:478.
4. World Health Organization. 1986. Severe and complicated malaria. Trans. R. Soc. Trop. Med. Hyg. 80(Suppl.):1.
5. World Health Organization. 1990. Severe and complicated malaria, 2nd Ed. Trans. R. Soc. Trap. Med. Hyg. 84(Suppl. 2):1.
6. Lemercier, G. 1969. Le neopaludisme aspects electroencephaliques, neuropathologiques. Pathol. Biol. 17:459.
7. Molyneux, M. E., T. E. Taylor, J. J. Wirma, and A. Borgstien. 1989. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawain children. Q. J. Med. 71:441.
8. + T lymphocytes play a major role in the pathogenesis of murine cerebral malaria. J. Immunol. 137:2348.
9. Rest, J. 1982. Cerebral malaria in inbred mice. I. A new model and its pathology. Trans. R. Soc. Trop. Med. Hyg. 76:410.
10. Wright, D. H. 1968. The effect of thymectomy on the survival of golden hamsters infected with Plasmodium berghei. Br. J. Exp. Pathol. 49:379.
11. Wright, D. H., R. M. Masembe, and E. R. Bazira. 1971. The effect of antithymocyte serum on golden hamsters and rats infected with Plasmodium berghei. Br. J. Exp. Pathol., 52:465.
12. Finley, R. W., L. J. Mackey, and P. H. Lambert. 1982. Virulent P. berghei malaria: prolonged survival and decreased cerebral pathology in cell-dependent nude mice. J. Immunol. 129:2213.
13. Clark, I. A., K. A. Rockett, and W. B. Cowden. 1992. TNF in malaria. In Tumor Necrosis Factor: The Molecules and Their Emerging Roles in Medicine. B. Beutler, ed. Raven Press, New York, pp. 308-328.
14. Grau, G. E., P.-F. Piguet, P. Vassalli, and P.-H. Lambert. 1989. Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data. Immunol. Rev: 112:49.
15. Grau, G. E., L. F. Fajardo, P.-F. Piguet, B. Allet, P.-H. Lambert, and P. Vassalli. 1987. Tumor-necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 237:1210.
16. de Kossodo, S., and G. E. Grau. 1993. Profiles of cytokine production in relation with susceptibility to cerebral malaria. J. Immunol. 151:4811.
17. Grau, G. E., H. Heremans, P.-F. Piguet, P. Pointaire, P.-H. Lambert, A. Billiau, and P. Vassalli. 1987. Monoclonal antibody against interferon-γ can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor. Proc. Natl. Acad. Sci. USA 86:5572.
18. Curfs, J. H. A., P. H. van der Meide, A. Billiau, J. H. E. Th. Meuwissen, and W. M. Eling. 1993. Plasmodium berghei: recombinant interferon-γ and the development of parasitemia and cerebral lesions in malaria-infected mice. Exp. Parasitol. 77:212.
19. Adam, C., M. Geniteau, M. Gougerot-Pocidalo, P. Verroust, J. Lebras, C. Gilbert, and L. Morel-Maroger. 1981. Cryoglobulins, circulating immune complexes and complement activation in cerebral malaria. Infect. Immun. 31:530.
20. Grau, G. E., and C. Behr. 1994. T cells and malaria: is Th1 cell activation a prerequisite for pathology? Res. Immunol. 145:441.
21. Viville, S., J. Neefjes, V. Lotteau, A. Dierich, M. Lemeur, H. Ploegh, C. Benoist, and D. Mathis. 1993. Mice lacking the MHC class II-associated invariant chain. Cell 72:635.
22. Cosgrove, D., D. Gray, A. Dierich, J. Kaufman, M. Lemur, C. Benoist, and D. Mathis. 1991. Mice lacking MHC class II molecules. Cell 66:1051.
23. Dalton, D., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739.
24. Schorle, H., T. Holtschke, T. Hündig, A. Schimpl, and I. Horak. 1991. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 352:621.
25. Kuhn, R., and K. Rajewsky. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254:707.
26. Kuhn, R., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263.
27. H locus. Int. Immunol. 5:647.
28. Ehlich, A., S. Schaal, H. J. Gu, D. Kitamura, W. Müller, and K. Rajewsky. 1993. Immunoglobulin heavy and light chains rearrange independently at early stages of B cell development. Cell 72:695.
29. + T cells. Science 248:1227.
30. + cytolytic T cells. Nature 344:742.
31. Stevenson, M. M. 1989. Genetic control of host resistance to malaria. In Malaria: Host Responses to Infection. M. M. Stevenson, ed. CRC, Boca Raton, FL, pp. 147-161.
32. Grun, J. L., and W. P. Weidanz. 1981. Immunity to Plasmodium chabaudi adami in the B-cell-deficient mouse. Nature 290:143.
33. -, γδ T cell subset in the spleens of mice during non-lethal blood-stage malaria. Eur. J. Immunol. 23:1846.
34. - T cells acquire specific lymphokine secretion potentials during thymic maturation. Nature 353:68.
35. Bendelac, A., P. Matzinger, R. A. Seder, W. E. Paul, and R. H. Schwartz. 1992. Activation events during thymic maturation. J. Exp. Med. 175:731.
36. + T cell subsets: a subset (Thy0) that secretes diverse cytokines and overexpresses the Vβ8 T cell receptor gene family. J. Exp. Med. 176:269.
37. - thymocytes with specific lymphokine secretion. Eur. J. Immunol. 23:307.
38. + cells in the liver of mice. J. Exp. Med. 180:699.
39. - thymocytes by class I molecules expressed by hematopoietic cells. J. Exp. Med 178:901.
40. + thymocytes. J. Exp. Med. 178:901.
41. pos T cells promptly produced interleukin-4 in response to in vivo challenge with anti-CD3. J. Exp. Med 179:1285.
42. Kündig, T., M. H. Schorle, M. F. Bachmann, H. Hengartner, R. M. Zinkernagel, and I. Horak. 1993. Immune responses in interleukin-2-deficient mice. Science 262:1059.
43. Weidanz, W. P., J. Melancon-Kaplan, and L. A. Cavacini. 1990. Cell-mediated immunity to the asexual blood stages of malarial parasites: animal models. Immunol. Lett. 25:87.
44. + T cells in the protective immune response to Plasmodium chabaudi in vivo. Immunol. Lett. 25:101.
45. Waki, S., S. Uehara, K. Kanbe, K. Ono, M. Suzuki, and H. Nariuchi. 1992. The role of T cells in pathogenesis and protective immunity to murine malaria. Immunology 75:646.
46. Imai, Y., and T. Kamiyama. 1994. T lymphocyte-dependent development of cerebral symptoms in WM/Ms rats infected with Plasmodium berghei. Ann. Trop. Med. Parasitol. 88:83.