-
1
-
-
15044338866
-
The global distribution of clinical episodes of Plasmodium falciparum malaria
-
Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI: The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 2005, 434:214-217
-
(2005)
Nature
, vol.434
, pp. 214-217
-
-
Snow, R.W.1
Guerra, C.A.2
Noor, A.M.3
Myint, H.Y.4
Hay, S.I.5
-
2
-
-
0034761722
-
Pathogenesis of cerebral malaria: Recent experimental data and possible applications for humans
-
Lou J, Lucas R, Grau GE: Pathogenesis of cerebral malaria: recent experimental data and possible applications for humans. Clin Microbiol Rev 2001, 14:810-820
-
(2001)
Clin Microbiol Rev
, vol.14
, pp. 810-820
-
-
Lou, J.1
Lucas, R.2
Grau, G.E.3
-
3
-
-
25444475850
-
Immunological processes in malaria pathogenesis
-
Schofield L, Grau GE: Immunological processes in malaria pathogenesis. Nat Rev Immunol 2005, 5:722-735
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 722-735
-
-
Schofield, L.1
Grau, G.E.2
-
4
-
-
0023189866
-
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria
-
Grau GE, Fajardo LF, Piguet PF, Allet B, Lambert PH, Vassalli P: Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 1987, 237:1210-1212
-
(1987)
Science
, vol.237
, pp. 1210-1212
-
-
Grau, G.E.1
Fajardo, L.F.2
Piguet, P.F.3
Allet, B.4
Lambert, P.H.5
Vassalli, P.6
-
5
-
-
0031012981
-
Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response
-
Rudin W, Eugster HP, Bordmann G, Bonato J, Muller M, Yamage M, Ryffel B: Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response. Am J Pathol 1997, 150:257-266
-
(1997)
Am J Pathol
, vol.150
, pp. 257-266
-
-
Rudin, W.1
Eugster, H.P.2
Bordmann, G.3
Bonato, J.4
Muller, M.5
Yamage, M.6
Ryffel, B.7
-
6
-
-
0343618458
-
Involvement of IFN-gamma receptor-medicated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection
-
Amani V, Vigario AM, Belnoue E, Marussig M, Fonseca L, Mazier D, Renia L: Involvement of IFN-gamma receptor-medicated signaling in pathology and anti-malarial immunity induced by Plasmodium berghei infection. Eur J Immunol 2000, 30:1646-1655
-
(2000)
Eur J Immunol
, vol.30
, pp. 1646-1655
-
-
Amani, V.1
Vigario, A.M.2
Belnoue, E.3
Marussig, M.4
Fonseca, L.5
Mazier, D.6
Renia, L.7
-
7
-
-
0032695542
-
Role of ICAM-1 (CD54) in the development of murine cerebral malaria
-
Favre N, Da Laperousaz C, Ryffel B, Weiss NA, Imfiof BA, Rudin W, Lucas R, Piguet PF: Role of ICAM-1 (CD54) in the development of murine cerebral malaria. Microbes Infect 1999, 1:961-968
-
(1999)
Microbes Infect
, vol.1
, pp. 961-968
-
-
Favre, N.1
Da Laperousaz, C.2
Ryffel, B.3
Weiss, N.A.4
Imfiof, B.A.5
Rudin, W.6
Lucas, R.7
Piguet, P.F.8
-
8
-
-
0037141025
-
Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria
-
Engwerda CR, Mynott TL, Sawhney S, De Souza JB, Bickle QD, Kaye PM: Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med 2002, 195:1371-1377
-
(2002)
J Exp Med
, vol.195
, pp. 1371-1377
-
-
Engwerda, C.R.1
Mynott, T.L.2
Sawhney, S.3
De Souza, J.B.4
Bickle, Q.D.5
Kaye, P.M.6
-
9
-
-
0037290876
-
Mammalian Toll-like receptors
-
Akira S: Mammalian Toll-like receptors. Curr Opin Immunol 2003, 15:5-11
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 5-11
-
-
Akira, S.1
-
10
-
-
33646183566
-
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
-
Beutler B, Jiang Z, Georgel P, Crozat K, Croker B, Rutschmann S, Du X, Hoebe K: Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol 2006, 24:353-389
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 353-389
-
-
Beutler, B.1
Jiang, Z.2
Georgel, P.3
Crozat, K.4
Croker, B.5
Rutschmann, S.6
Du, X.7
Hoebe, K.8
-
11
-
-
19944430901
-
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S: Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med 2005, 201:19-25
-
(2005)
J Exp Med
, vol.201
, pp. 19-25
-
-
Coban, C.1
Ishii, K.J.2
Kawai, T.3
Hemmi, H.4
Sato, S.5
Uematsu, S.6
Yamamoto, M.7
Takeuchi, O.8
Itagaki, S.9
Kumar, N.10
Horii, T.11
Akira, S.12
-
12
-
-
14844337835
-
Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: Cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity
-
Krishnegowda G, Hajjar AM, Zhu J, Douglass EJ, Uematsu S, Akira S, Woods AS, Gowda DC: Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity. J Biol Chem 2005, 280:8606-8616
-
(2005)
J Biol Chem
, vol.280
, pp. 8606-8616
-
-
Krishnegowda, G.1
Hajjar, A.M.2
Zhu, J.3
Douglass, E.J.4
Uematsu, S.5
Akira, S.6
Woods, A.S.7
Gowda, D.C.8
-
13
-
-
26244442975
-
Stimulation of innate immune responses by malarial glycosylphosphatidylinositol via pattern recognition receptors
-
Nebl T, De Veer MJ, Schofield L: Stimulation of innate immune responses by malarial glycosylphosphatidylinositol via pattern recognition receptors. Parasitology 2005, 130:S45-S62
-
(2005)
Parasitology
, vol.130
-
-
Nebl, T.1
De Veer, M.J.2
Schofield, L.3
-
14
-
-
0037102205
-
Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria
-
Schofield L, Hewitt MC, Evans K, Siomos MA, Seeberger PH: Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature 2002, 418:785-789
-
(2002)
Nature
, vol.418
, pp. 785-789
-
-
Schofield, L.1
Hewitt, M.C.2
Evans, K.3
Siomos, M.A.4
Seeberger, P.H.5
-
15
-
-
26844548625
-
Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum
-
Baratin M, Roetynck S, Lepolard C, Falk C, Sawadogo S, Uematsu S, Akira S, Ryffel B, Tiraby JG, Alexopoulou L, Kirschning CJ, Gysin J, Vivier E, Ugolini S: Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum. Proc Natl Acad Sci USA 2005, 102:14747-14752
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14747-14752
-
-
Baratin, M.1
Roetynck, S.2
Lepolard, C.3
Falk, C.4
Sawadogo, S.5
Uematsu, S.6
Akira, S.7
Ryffel, B.8
Tiraby, J.G.9
Alexopoulou, L.10
Kirschning, C.J.11
Gysin, J.12
Vivier, E.13
Ugolini, S.14
-
16
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, Modlin RL, Akira S: Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 2002, 169:10-14
-
(2002)
J Immunol
, vol.169
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
17
-
-
0035854686
-
The role of Toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2
-
Michelsen KS, Aicher A, Mohaupt M, Hartung T, Dimmeler S, Kirschning CJ, Schumann RR: The role of Toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2. J Biol Chem 2001, 276:25680-25686
-
(2001)
J Biol Chem
, vol.276
, pp. 25680-25686
-
-
Michelsen, K.S.1
Aicher, A.2
Mohaupt, M.3
Hartung, T.4
Dimmeler, S.5
Kirschning, C.J.6
Schumann, R.R.7
-
18
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA: Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001, 413:732-738
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
19
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product
-
Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S: Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 1999, 162:3749-3752
-
(1999)
J Immunol
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
20
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S: Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001, 13:933-940
-
(2001)
Int Immunol
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
21
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, Horiuchi T, Tomizawa H, Takeda K, Akira S: Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002, 3:196-200
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
22
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S: A Toll-like receptor recognizes bacterial DNA, Nature 2000, 408:740-745
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
23
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng T, Barton GM, Flavell RA, Medzhitov R: The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002, 420:329-333
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
24
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S: Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999, 11:115-122
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
25
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B: Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 2003, 424:743-748
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
Crozat, K.11
Sovath, S.12
Han, J.13
Beutler, B.14
-
26
-
-
0028979065
-
Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness
-
Banks TA, Rouse BT, Kerley MK, Blair PJ, Godfrey VL, Kuklin NA, Bouley DM, Thomas J, Kanangat S, Mucenski ML: Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness. J Immunol 1995, 155:1685-1693
-
(1995)
J Immunol
, vol.155
, pp. 1685-1693
-
-
Banks, T.A.1
Rouse, B.T.2
Kerley, M.K.3
Blair, P.J.4
Godfrey, V.L.5
Kuklin, N.A.6
Bouley, D.M.7
Thomas, J.8
Kanangat, S.9
Mucenski, M.L.10
-
27
-
-
0037108521
-
Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice
-
Yang KK, Dorner BG, Merkel U, Ryffel B, Schutt C, Golenbock D, Freeman MW, Jack RS: Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice. J Immunol 2002, 169:4475-4480
-
(2002)
J Immunol
, vol.169
, pp. 4475-4480
-
-
Yang, K.K.1
Dorner, B.G.2
Merkel, U.3
Ryffel, B.4
Schutt, C.5
Golenbock, D.6
Freeman, M.W.7
Jack, R.S.8
-
28
-
-
23844535777
-
Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration
-
Franke-Fayard B, Janse CJ, Cunha-Rodrigues M, Ramesar J, Buscher P, Que I, Lowik C, Voshol PJ, den Boer MA, van Duinen SG, Febbraio M, Mota MM, Waters AP: Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci USA 2005, 102:11468-11473
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11468-11473
-
-
Franke-Fayard, B.1
Janse, C.J.2
Cunha-Rodrigues, M.3
Ramesar, J.4
Buscher, P.5
Que, I.6
Lowik, C.7
Voshol, P.J.8
den Boer, M.A.9
van Duinen, S.G.10
Febbraio, M.11
Mota, M.M.12
Waters, A.P.13
-
29
-
-
0029751937
-
Correction or transfer of immunodeficiency due to TNF-LT alpha deletion by bone marrow transplantation
-
Muller M, Eugster HP, Le Hir M, Shakhov A, Di Padova F, Maurer C, Quesniaux VF, Ryffel B: Correction or transfer of immunodeficiency due to TNF-LT alpha deletion by bone marrow transplantation. Mol Med 1996, 2:247-255
-
(1996)
Mol Med
, vol.2
, pp. 247-255
-
-
Muller, M.1
Eugster, H.P.2
Le Hir, M.3
Shakhov, A.4
Di Padova, F.5
Maurer, C.6
Quesniaux, V.F.7
Ryffel, B.8
-
31
-
-
0024210917
-
Immunopathology of thrombocytopenia in experimental malaria
-
Grau GE, Piguet PF, Gretener D, Vesin C, Lambert PH: Immunopathology of thrombocytopenia in experimental malaria. Immunology 1988, 65:501-506
-
(1988)
Immunology
, vol.65
, pp. 501-506
-
-
Grau, G.E.1
Piguet, P.F.2
Gretener, D.3
Vesin, C.4
Lambert, P.H.5
-
32
-
-
0035889873
-
Plasmodium berghei infection in mice induces liver injury by an IL-12-and Toll-like receptor/myeloid differentiation factor 88-dependent mechanism
-
Adachi K, Tsutsui H, Kashiwamura S, Seki E, Nakano H, Takeuchi O, Takeda K, Okumura K, Van Kaer L, Okamura H, Akira S, Nakanishi K: Plasmodium berghei infection in mice induces liver injury by an IL-12-and Toll-like receptor/myeloid differentiation factor 88-dependent mechanism. J Immunol 2001, 167:5928-5934
-
(2001)
J Immunol
, vol.167
, pp. 5928-5934
-
-
Adachi, K.1
Tsutsui, H.2
Kashiwamura, S.3
Seki, E.4
Nakano, H.5
Takeuchi, O.6
Takeda, K.7
Okumura, K.8
Van Kaer, L.9
Okamura, H.10
Akira, S.11
Nakanishi, K.12
-
33
-
-
27744448143
-
Innate immunity to mycobacterial infection in mice: Critical role for Toll-like receptors
-
Ryffel B, Fremond C, Jacobs M, Parida S, Botha T, Schnyder B, Ouesniaux V: Innate immunity to mycobacterial infection in mice: critical role for Toll-like receptors. Tuberculosis (Edinb) 2005, 85:395-405
-
(2005)
Tuberculosis (Edinb)
, vol.85
, pp. 395-405
-
-
Ryffel, B.1
Fremond, C.2
Jacobs, M.3
Parida, S.4
Botha, T.5
Schnyder, B.6
Ouesniaux, V.7
-
34
-
-
27444439702
-
Comparative genomics of malaria parasites
-
Hall N, Carlton J: Comparative genomics of malaria parasites. Curr Opin Genet Dev 2005, 15:609-613
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 609-613
-
-
Hall, N.1
Carlton, J.2
-
36
-
-
4444291696
-
Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP 1(42) formulated with novel adjuvants or with alum
-
Pichyangkul S, Gettayacamin M, Miller RS, Lyon JA, Angov E, Tongtawe P, Ruble DL, Heppner Jr DG, Kester KE, Ballou WR, Diggs CL, Voss G, Cohen JD, Walsh DS: Pre-clinical evaluation of the malaria vaccine candidate P. falciparum MSP 1(42) formulated with novel adjuvants or with alum. Vaccine 2004, 22:3831-3840
-
(2004)
Vaccine
, vol.22
, pp. 3831-3840
-
-
Pichyangkul, S.1
Gettayacamin, M.2
Miller, R.S.3
Lyon, J.A.4
Angov, E.5
Tongtawe, P.6
Ruble, D.L.7
Heppner Jr, D.G.8
Kester, K.E.9
Ballou, W.R.10
Diggs, C.L.11
Voss, G.12
Cohen, J.D.13
Walsh, D.S.14
-
37
-
-
32244432768
-
-
Lee HK, Dunzendorfer S, Soldau K, Tobias PS: Double-stranded RNA-mediated TLR3 activation is enhanced by CD 14, Immunity 2006, 24:153-163
-
Lee HK, Dunzendorfer S, Soldau K, Tobias PS: Double-stranded RNA-mediated TLR3 activation is enhanced by CD 14, Immunity 2006, 24:153-163
-
-
-
-
39
-
-
33845972672
-
Markers of sulfadoxine-pyrimethamine resistant falciparum malaria in placenta and circulation of pregnant women
-
Mockenhaupt FP, Bedu-Addo G, Junge C, Hommerich L, Eggelte TA, Bienzle U: Markers of sulfadoxine-pyrimethamine resistant falciparum malaria in placenta and circulation of pregnant women. Antimicrob Agents Chemother 2007, 51:332-334
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 332-334
-
-
Mockenhaupt, F.P.1
Bedu-Addo, G.2
Junge, C.3
Hommerich, L.4
Eggelte, T.A.5
Bienzle, U.6
|