Chronic cerebral hypoperfusion alters amyloid-β peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice

Clinical Science

Volumn 131, Issue 16, 2017, Pages 2109-2123

  Salvadores, Natalia ^a,b   Searcy, James L ^a   Holland, Philip R ^a,c   Horsburgh, Karen ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSIDAD MAYOR   (Chile)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (40-42); CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; PEPTIDE FRAGMENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; CHRONIC CEREBRAL HYPOPERFUSION; CONTROLLED STUDY; DEMENTIA; DISEASE EXACERBATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARENCHYMA; PERFUSION; PRIORITY JOURNAL; VASCULAR AMYLOIDOSIS; ANIMAL; BRAIN; BRAIN CIRCULATION; BRAIN ISCHEMIA; CHRONIC DISEASE; COMPLICATION; DISEASE MODEL; METABOLISM; PATHOLOGY; PHYSIOLOGY; SOLUBILITY; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; ANIMALS; BRAIN; BRAIN ISCHEMIA; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL HEMORRHAGE; CEREBRAL INFARCTION; CEREBROVASCULAR CIRCULATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; MEMBRANE GLYCOPROTEINS; MICE, TRANSGENIC; NADPH OXIDASE 2; NADPH OXIDASES; OXIDATIVE STRESS; PARENCHYMAL TISSUE; PEPTIDE FRAGMENTS; SOLUBILITY;

EID: 85026807320     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20170962     Document Type: Article

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