Effect of ischemic neuronal insults on amyloid precursor protein processing

Neurochemical Research

Volumn 31, Issue 6, 2006, Pages 821-827

  Lee, Phil Hyu ^a   Hwang, Eun Mi ^b   Hong, Hyun Seok ^b   Boo, Jung Hyun ^b   Mook Jung, Inhee ^b   Huh, Kyoon ^a  

^a Ajou University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Alzheimer's disease; Amyloid precursor protein processing; Ischemic insults

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; DISINTEGRIN; GAMMA SECRETASE; GLUCOSE; MESSENGER RNA; METALLOPROTEINASE; METALLOPROTEINASE ADAM 10; OXYGEN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN OXYGEN CONSUMPTION; CONTROLLED STUDY; ENZYME ACTIVITY; EVALUATION; FETUS; GLUCOSE BRAIN LEVEL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS REGULATION; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; AMYLOID; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; BRAIN ISCHEMIA; CELL LINE, TUMOR; DNA PRIMERS; ENDOPEPTIDASES; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL;

MUS MUSCULUS;

EID: 33746341185     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9086-y     Document Type: Article

References (25)

1. Breteler MM (2000) Vascular risk factors for Alzheimer's disease an epidemiological study. Neurobiol Aging 21:153-160
2. Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN (1996) Apolipoprotein E e4 alleles in CAA and cerebrovascular pathology in Alzheimer's disease. Am J Pathol 148:2083-2095
3. Kalaria RN, Ballard C (1999) Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimer Dis Assoc Disord 13:S115-S123
4. Selkoe DJ (1998) The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 8:447-453
5. Nunan J, Small DH (2000) Regulation of APP cleavage by α-, β- and γ-secretases. FEBS Lett 483:6-10
6. Bennett SAL, Pappas BA, Stevens WD, Davidson CM, Fortin T, Chen J (2000) Cleavage of amyloid precursor protein elicited by chronic cerebral hypoperfusion. Neurobiol Aging 21:207-214
7. Nihashi T, Inao S, Kajita Y, Kawai T, Sugimoto T, Niwa M, Kabeya R, Hata N, Hayashi S, Yoshida J (2001) Expression and distribution of beta amyloid precursor protein and beta amyloid peptide in reactive astrocytes after transient middle cerebral artery occlusion. Acta Neurochir 143:287-295
8. Shi J, Yang SH, Stubley L, Day AL, Simpkins JW (2000) Hypoperfusion induces overexpression of beta-amyloid precursor protein mRNA in a focal ischemic rodent model. Brain Res 853:1-4
9. Farmery MR, Tjernberg LO, Pursglove SE, Bergman A, Winblad B, Naslund J (2003) Partial purification and characterization of gamma-secretase from post-mortem human brain. J Biol Chem 278:24277-24284
10. Lammich S, Kojro E, Postina R, Gilbert S, Pfeiffer R, Jasionowski M, Haass C, Fahrenholz F (1999) Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. Proc Natl Acad Sci USA 96:3922-3927
11. Asai M, Hattori C, Szabo B, Sasagawa N, Maruyama K, Tanuma S, Ishiura S (2003) Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase. Biochem Biophys Res Commun 301:231-235
12. Bernstein HG, Bukowska A, Krell D, Bogerts B, Ansorge S, Lendeckel U (2003) Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome. J Neurocytol 32:153-160
13. Hurtado O, Cardenas A, Lizasoain I, Bosca L, Leza JC, Lorenzo P, Moro MA (2001) Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices. Neuropharmacology 40:1094-1102
14. Hurtado O, Lizasoain I, Fernandez-Tome P, Alvarez-Barrientos A, Leza JC, Lorenzo P, Moro MA (2002) TACE/ADAM17-TNF-alpha pathway in rat cortical cultures after exposure to oxygen-glucose deprivation or glutamate. J Cereb Blood Flow Metab 22:576-585
15. Cardenas A, Moro MA, Leza JC, O'Shea E, Davalos A, Castillo J, Lorenzo P, Lizasoain I (2002) Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance. J Cereb Blood Flow Metab 22:1297-1302
16. Sinha S, Anderson JP, Barbour R (1999) Purification and cloning of amyloid precursor protein β-secretase from human brain. Nature 402:537-540
17. Fukumoto H, Cheung BS, Hyman BT, Irizarry M (2002) β-secretase protein and activity are increased in the neocortex in Alzheimer disease. Arch Neurol 59:1381-1389
18. Gatta LB, Albertini A, Ravid R, Finazzi D (2002) Levels of beta-secretase BACE and alpha-secretase ADAM10 mRNAs in Alzheimer hippocampus. Neuroreport 13:2031-2033
19. Preece P, Virley DJ, Costandi M, Coombes R, Moss SJ, Mudge AW, Jazin E, Cairns NJ (2003) Beta-secretase (BACE) and GSK-3 mRNA levels in Alzheimer's disease. Brain Res Mol Brain Res 116:155-158
20. Tamagno E, Bardini P, Obbili A, Vitali A, Borghi R, Zaccheo D, Pronzato MA, Danni O, Smith MA, Perry G, Tabaton M (2002) Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis 10:279-288
21. De Strooper B, Saftig P, Craessaerts K, Vanderstichele H, Guhde G, Annaert W, Von Figura K, Van Leuven F (1998) Deficiency of presenillin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391:387-390
22. Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med 3:67-72
23. Iwatsubo T (2004) The gamma-secretase complex: machinery for intramembrane proteolysis. Curr Opin Neurobiol 14:379-383
24. Tanimukai H, Imaizumi K, Kudo T, Katayama T, Tsuda M, Takagi T, Tohyama M, Takeda M (1998) Alzheimer-associated presenilin-1 gene is induced in gerbil hippocampus after transient ischemia. Brain Res Mol Brain Res 54:212-218
25. Pennypacker KR, Hernandez H, Benkovic S, Morgan DG, Willing AE, Sanberg PR (1999) Induction of presenilins in the rat brain after middle cerebral arterial occlusion. Brain Res Bull 48:539-543