Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch

Nucleic Acids Research

Volumn 45, Issue 13, 2017, Pages

  Hirosawa, Moe ^a,b   Fujita, Yoshihiko ^a   Parr, Callum J C ^a   Hayashi, Karin ^a   Kashida, Shunnichi ^a   Hotta, Akitsu ^a   Woltjen, Knut ^a,c   Saito, Hirohide ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; CRISPR ASSOCIATED PROTEIN; MICRORNA; MICRORNA 21; MICRORNA 21 5P; MICRORNA 302; MICRORNA 302A 5P; UNCLASSIFIED DRUG; 5' UNTRANSLATED REGION; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; ENDONUCLEASE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; GUIDE RNA; SYNTHETIC DNA;

5' UNTRANSLATED REGION; ARTICLE; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EDITING; GENE SWITCHING; HELA CELL LINE; HUMAN; HUMAN CELL; NERVE CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; TARGET CELL; ALU SEQUENCE; CELL DIFFERENTIATION; COCULTURE; CRISPR CAS SYSTEM; CYTOLOGY; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; PROCEDURES; REGULATOR GENE;

5' UNTRANSLATED REGIONS; ALU ELEMENTS; BACTERIAL PROTEINS; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; CRISPR-CAS SYSTEMS; ENDONUCLEASES; GENE EDITING; GENES, SWITCH; GENES, SYNTHETIC; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICRORNAS; NEURONS; RNA, GUIDE;

EID: 85026446269     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkx309     Document Type: Article

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