The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a

Cell

Volumn 170, Issue 4, 2017, Pages 714-726.e10

  Liu, Liang ^a   Li, Xueyan ^a,b   Ma, Jun ^a   Li, Zongqiang ^a   You, Lilan ^a,b   Wang, Jiuyu ^a   Wang, Min ^a   Zhang, Xinzheng ^a,b   Wang, Yanli ^a,b,c  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

C2c2; Cas13a; CRISPR Cas; RNA guided RNA cleavage; RNase

Indexed keywords

CAS13A PROTEIN; CRRNA; RIBONUCLEASE; RNA; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL RNA; CRISPR ASSOCIATED PROTEIN; GUIDE RNA; VIRUS RNA;

ARTICLE; BACTERIAL GENE; CAS13A GENE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRYSTAL STRUCTURE; GENE ACTIVATION; GENE DUPLICATION; GENE TARGETING; LEPTOTRICHIA BUCCALIS; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA BINDING; RNA CLEAVAGE; RNA CONFORMATION; RNA PROCESSING; RNA STRUCTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; LEPTOTRICHIA; METABOLISM; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; ULTRASTRUCTURE; VIROLOGY; X RAY DIFFRACTION;

BACTERIAL PROTEINS; BASE SEQUENCE; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; LEPTOTRICHIA; MODELS, MOLECULAR; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, BACTERIAL; RNA, GUIDE; RNA, VIRAL; X-RAY DIFFRACTION;

EID: 85026197774     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.06.050     Document Type: Article

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