메뉴 건너뛰기




Volumn 69, Issue , 2017, Pages 214-219

Revisiting the mechanisms of ACE inhibitory peptides from food proteins

Author keywords

ACE inhibition; ACE2; Antihypertension; Bioactive peptides; Cardiovascular disease; Endothelial function; Inflammation; Metabolic syndrome; Vascular oxidation

Indexed keywords

BIOCHEMISTRY; BLOOD PRESSURE; ENZYMES; METABOLISM; PATHOLOGY; PEPTIDES;

EID: 85024926621     PISSN: 09242244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tifs.2017.07.011     Document Type: Note
Times cited : (150)

References (73)
  • 2
    • 33747455671 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor-related angioedema: How to deal with it
    • Beltrami, L., Zingale, L.C., Carugo, S., Cicardi, M., Angiotensin-converting enzyme inhibitor-related angioedema: How to deal with it. Expert Opinion on Drug Safety 5 (2006), 643–649.
    • (2006) Expert Opinion on Drug Safety , vol.5 , pp. 643-649
    • Beltrami, L.1    Zingale, L.C.2    Carugo, S.3    Cicardi, M.4
  • 3
    • 0035955760 scopus 로고    scopus 로고
    • Novel clinical markers of vascular wall inflammation
    • Blake, G.J., Ridker, P.M., Novel clinical markers of vascular wall inflammation. Circulation Research 89 (2001), 763–771.
    • (2001) Circulation Research , vol.89 , pp. 763-771
    • Blake, G.J.1    Ridker, P.M.2
  • 4
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai, H., Harrison, D.G., Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress. Circulation Research 87 (2000), 840–844.
    • (2000) Circulation Research , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 5
    • 79959288378 scopus 로고    scopus 로고
    • Blood pressure lowering effect of lactotripeptides assumed as functional foods: A meta-analysis of current available clinical trials
    • Cicero, A.F.G., Gerocarni, B., Laghi, L., Borghi, C., Blood pressure lowering effect of lactotripeptides assumed as functional foods: A meta-analysis of current available clinical trials. Journal of Human Hypertension 25 (2011), 425–436.
    • (2011) Journal of Human Hypertension , vol.25 , pp. 425-436
    • Cicero, A.F.G.1    Gerocarni, B.2    Laghi, L.3    Borghi, C.4
  • 8
    • 0027095863 scopus 로고
    • Angiotensin-converting enzyme-inhibitors and insulin sensitivity-metabolic effects in hypertension, diabetes, and heart-failure
    • Donnelly, R., Angiotensin-converting enzyme-inhibitors and insulin sensitivity-metabolic effects in hypertension, diabetes, and heart-failure. Journal of Cardiovascular Pharmcology 20 (1992), S38–S44.
    • (1992) Journal of Cardiovascular Pharmcology , vol.20 , pp. S38-S44
    • Donnelly, R.1
  • 9
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • Donoghue, M., Hsieh, F., Baronas, E., Godbout, K., Gosselin, M., Stagliano, N., et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circulation Research 87 (2000), e1–e9.
    • (2000) Circulation Research , vol.87 , pp. e1-e9
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3    Godbout, K.4    Gosselin, M.5    Stagliano, N.6
  • 10
    • 78751649673 scopus 로고    scopus 로고
    • Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation
    • Ehlers, P.I., Nurmi, L., Turpeinen, A.M., Korpela, R., Vapaatalo, H., Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation. Life Sciences 88 (2011), 206–211.
    • (2011) Life Sciences , vol.88 , pp. 206-211
    • Ehlers, P.I.1    Nurmi, L.2    Turpeinen, A.M.3    Korpela, R.4    Vapaatalo, H.5
  • 11
    • 84900530306 scopus 로고    scopus 로고
    • The impact of milk proteins and peptides on blood pressure and vascular function: A review of evidence from human intervention studies
    • Fekete, A.A., Givens, D.I., Lovegrove, J.A., The impact of milk proteins and peptides on blood pressure and vascular function: A review of evidence from human intervention studies. Nutrition Research Reviews 26 (2013), 177–190.
    • (2013) Nutrition Research Reviews , vol.26 , pp. 177-190
    • Fekete, A.A.1    Givens, D.I.2    Lovegrove, J.A.3
  • 13
    • 4944250523 scopus 로고    scopus 로고
    • Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: Further evidence for the existence of the “vulnerable” patient
    • Fichtlscherer, S., Breuer, S., Zeiher, A.M., Prognostic value of systemic endothelial dysfunction in patients with acute coronary syndromes: Further evidence for the existence of the “vulnerable” patient. Circulation 110 (2004), 1926–1932.
    • (2004) Circulation , vol.110 , pp. 1926-1932
    • Fichtlscherer, S.1    Breuer, S.2    Zeiher, A.M.3
  • 16
    • 0029902995 scopus 로고    scopus 로고
    • Vasorelaxation by Casomokinin L, a derivative of h-Casomorphin and Casoxin D, is mediated by NK1 receptor
    • Fujita, H., Suganuma, H., Usui, H., Kurahashi, K., Nakagiri, R., Sasaki, R., et al. Vasorelaxation by Casomokinin L, a derivative of h-Casomorphin and Casoxin D, is mediated by NK1 receptor. Peptides 17 (1996), 635–639.
    • (1996) Peptides , vol.17 , pp. 635-639
    • Fujita, H.1    Suganuma, H.2    Usui, H.3    Kurahashi, K.4    Nakagiri, R.5    Sasaki, R.6
  • 17
    • 0029095148 scopus 로고
    • Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin
    • Fujita, H., Usui, H., Kurahashi, K., Yoshikawa, M., Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin. Peptides 16 (1995), 785–790.
    • (1995) Peptides , vol.16 , pp. 785-790
    • Fujita, H.1    Usui, H.2    Kurahashi, K.3    Yoshikawa, M.4
  • 18
    • 0037406338 scopus 로고    scopus 로고
    • Endothelial dysfunction and inflammation: What is the link?
    • Galle, J., Quaschning, T., Seibold, s., Wanner, C., Endothelial dysfunction and inflammation: What is the link?. Kidney International 84 (2003), S45–S49.
    • (2003) Kidney International , vol.84 , pp. S45-S49
    • Galle, J.1    Quaschning, T.2    Seibold, S.3    Wanner, C.4
  • 23
    • 84855726245 scopus 로고    scopus 로고
    • Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings
    • Hirota, T., Nonaka, A., Matsushita, A., Uchida, N., Ohki, K., Asakura, M., et al. Milk casein-derived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings. Heart and Vessels 26 (2011), 549–556.
    • (2011) Heart and Vessels , vol.26 , pp. 549-556
    • Hirota, T.1    Nonaka, A.2    Matsushita, A.3    Uchida, N.4    Ohki, K.5    Asakura, M.6
  • 25
    • 75749157000 scopus 로고    scopus 로고
    • Cardiovascular activity of milk casein-derived tripeptides and plant sterols in spontaneously hypertensive rats
    • Jakala, P., Pere, E., Lehtinen, R., Turpeinen, A., Korpela, R., Vapaatalo, H., Cardiovascular activity of milk casein-derived tripeptides and plant sterols in spontaneously hypertensive rats. Journal of Physiology Pharmacology 60 (2009), 11–20.
    • (2009) Journal of Physiology Pharmacology , vol.60 , pp. 11-20
    • Jakala, P.1    Pere, E.2    Lehtinen, R.3    Turpeinen, A.4    Korpela, R.5    Vapaatalo, H.6
  • 29
    • 33747503962 scopus 로고    scopus 로고
    • Bioactive peptides: Production and functionality
    • Korhonen, H., Pihlanto, A., Bioactive peptides: Production and functionality. International Dairy Journal 16 (2006), 945–960.
    • (2006) International Dairy Journal , vol.16 , pp. 945-960
    • Korhonen, H.1    Pihlanto, A.2
  • 30
    • 80054719529 scopus 로고    scopus 로고
    • Prediction of off-target effects on angiotensin converting enzyme 2
    • Kulemina, L.V., Ostrov, D., Prediction of off-target effects on angiotensin converting enzyme 2. Journal of Biomolecular Screening 16 (2011), 878–885.
    • (2011) Journal of Biomolecular Screening , vol.16 , pp. 878-885
    • Kulemina, L.V.1    Ostrov, D.2
  • 32
    • 33344456196 scopus 로고    scopus 로고
    • Oxidant stress - a major cause of reduced endothelial nitric oxide availability in cardiovascular disease
    • Landmesser, U., Harrison, D.G., Drexler, H., Oxidant stress - a major cause of reduced endothelial nitric oxide availability in cardiovascular disease. European Journal of Clinical Pharmacology 62 (2006), 13–19.
    • (2006) European Journal of Clinical Pharmacology , vol.62 , pp. 13-19
    • Landmesser, U.1    Harrison, D.G.2    Drexler, H.3
  • 33
    • 84872178401 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar–Kyoto rats and spontaneously hypertensive rats
    • Lo, J., Patel, V.B., Wang, Z., Levasseur, J., Kaufman, S., Penninger, J.M., et al. Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar–Kyoto rats and spontaneously hypertensive rats. Experimental Physiology 98 (2013), 109–122.
    • (2013) Experimental Physiology , vol.98 , pp. 109-122
    • Lo, J.1    Patel, V.B.2    Wang, Z.3    Levasseur, J.4    Kaufman, S.5    Penninger, J.M.6
  • 34
    • 0842324724 scopus 로고    scopus 로고
    • Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells
    • Maes, W., Van Camp, J., Vermeirssen, V., Hemeryck, M., Ketelslegers, J.M., Schrezenmeir, J., et al. Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells. Regulatory Peptides 118 (2004), 105–109.
    • (2004) Regulatory Peptides , vol.118 , pp. 105-109
    • Maes, W.1    Van Camp, J.2    Vermeirssen, V.3    Hemeryck, M.4    Ketelslegers, J.M.5    Schrezenmeir, J.6
  • 35
    • 84874839826 scopus 로고    scopus 로고
    • Structure and activity study of egg protein ovotransferrin derived peptides (IRW and IQW) on endothelial inflammatory response and oxidative stress
    • Majumder, K., Chakrabarti, S., Davidge, S.T., Wu, J., Structure and activity study of egg protein ovotransferrin derived peptides (IRW and IQW) on endothelial inflammatory response and oxidative stress. Journal of Agricultural and Food Chemistry 61 (2013), 2120–2129.
    • (2013) Journal of Agricultural and Food Chemistry , vol.61 , pp. 2120-2129
    • Majumder, K.1    Chakrabarti, S.2    Davidge, S.T.3    Wu, J.4
  • 36
    • 84896691651 scopus 로고    scopus 로고
    • Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats
    • Majumder, K., Chakrabarti, S., Morton, J., Sareh, P., Kaufman, S., Davidge, S.T., et al. Egg-derived tri-peptide IRW exerts antihypertensive effects in spontaneously hypertensive rats. PLoS One, 8, 2013, e82829.
    • (2013) PLoS One , vol.8 , pp. e82829
    • Majumder, K.1    Chakrabarti, S.2    Morton, J.3    Sareh, P.4    Kaufman, S.5    Davidge, S.T.6
  • 37
    • 84922569199 scopus 로고    scopus 로고
    • Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats
    • Majumder, K., Chakrabarti, S., Morton, J., Sareh, P., Kaufman, S., Davidge, S.T., et al. Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats. Journal of Functional Foods 13 (2015), 50–60.
    • (2015) Journal of Functional Foods , vol.13 , pp. 50-60
    • Majumder, K.1    Chakrabarti, S.2    Morton, J.3    Sareh, P.4    Kaufman, S.5    Davidge, S.T.6
  • 38
    • 84942826619 scopus 로고    scopus 로고
    • Egg ovotransferrin derived ACE inhibitory peptide IRWincreases ACE 2 but decreases pro-inflammatory genes expression in mesenteric artery of spontaneously hypertensive rats
    • Majumder, K., Liang, G., Chen, Y., Guan, L.L., Davidge, S.T., Wu, J., Egg ovotransferrin derived ACE inhibitory peptide IRWincreases ACE 2 but decreases pro-inflammatory genes expression in mesenteric artery of spontaneously hypertensive rats. Molecular Nutrition and Food Research 59 (2015), 1735–1744.
    • (2015) Molecular Nutrition and Food Research , vol.59 , pp. 1735-1744
    • Majumder, K.1    Liang, G.2    Chen, Y.3    Guan, L.L.4    Davidge, S.T.5    Wu, J.6
  • 39
    • 84919795223 scopus 로고    scopus 로고
    • Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertension
    • Majumder, K., Wu, J., Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertension. International Journal of Molecular Sciences 16:1 (2014), 256–283.
    • (2014) International Journal of Molecular Sciences , vol.16 , Issue.1 , pp. 256-283
    • Majumder, K.1    Wu, J.2
  • 40
    • 34547985546 scopus 로고    scopus 로고
    • Diketopiperazines: Biological activity and synthesis
    • Martins, M.B., Carvalho, I., Diketopiperazines: Biological activity and synthesis. Tetrahedron 63 (2007), 9923–9932.
    • (2007) Tetrahedron , vol.63 , pp. 9923-9932
    • Martins, M.B.1    Carvalho, I.2
  • 41
    • 0026938894 scopus 로고
    • Leukocyte-endothelial cell interactions
    • McEver, R.P., Leukocyte-endothelial cell interactions. Current Opinion in Cell Biology 4 (1992), 840–849.
    • (1992) Current Opinion in Cell Biology , vol.4 , pp. 840-849
    • McEver, R.P.1
  • 43
    • 27944465326 scopus 로고    scopus 로고
    • Short-term effect of egg white hydrolysate products on the arterial blood pressure of hypertensive rats
    • Miguel, M., López-Fandiño, R., Ramos, M., Aleixandre, A., Short-term effect of egg white hydrolysate products on the arterial blood pressure of hypertensive rats. British Journal of Nutrition 94 (2005), 731–737.
    • (2005) British Journal of Nutrition , vol.94 , pp. 731-737
    • Miguel, M.1    López-Fandiño, R.2    Ramos, M.3    Aleixandre, A.4
  • 44
    • 84947789206 scopus 로고    scopus 로고
    • Modification of peptide functionality during enzymatic hydrolysis of whey proteins
    • Mohan, A., Udechukwu, M.C., Rajendran, S.R., Udenigwe, C.C., Modification of peptide functionality during enzymatic hydrolysis of whey proteins. RSC Advances 5 (2015), 97400–97407.
    • (2015) RSC Advances , vol.5 , pp. 97400-97407
    • Mohan, A.1    Udechukwu, M.C.2    Rajendran, S.R.3    Udenigwe, C.C.4
  • 45
    • 41649116606 scopus 로고    scopus 로고
    • Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction
    • Münzel, T., Sinning, C., Post, F., Warnholtz, A., Schulz, E., Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction. Annals of Medicine 40 (2008), 180–196.
    • (2008) Annals of Medicine , vol.40 , pp. 180-196
    • Münzel, T.1    Sinning, C.2    Post, F.3    Warnholtz, A.4    Schulz, E.5
  • 46
    • 84877869409 scopus 로고    scopus 로고
    • Milk-derived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein E-deficient mice: A preliminary study
    • Nakamura, T., Hirota, T., Mizushima, K., Ohki, K., Naito, Y., Yamamoto, N., et al. Milk-derived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein E-deficient mice: A preliminary study. Journal of Medicinal Food 16 (2013), 396–403.
    • (2013) Journal of Medicinal Food , vol.16 , pp. 396-403
    • Nakamura, T.1    Hirota, T.2    Mizushima, K.3    Ohki, K.4    Naito, Y.5    Yamamoto, N.6
  • 47
    • 0029319296 scopus 로고
    • Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-Converting enzyme
    • Nakamura, Y., Yamamoto, N., Sakai, K., Takano, T., Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-Converting enzyme. Journal of Dairy Science 78 (1995), 1253–1257.
    • (1995) Journal of Dairy Science , vol.78 , pp. 1253-1257
    • Nakamura, Y.1    Yamamoto, N.2    Sakai, K.3    Takano, T.4
  • 48
    • 42349105833 scopus 로고    scopus 로고
    • Structure-based identification of small molecule angiotensin converting enzyme 2 activators as novel antihypertensive agents
    • Prada, J.A.H., Ferreira, A.J., Katovich, M.J., Shenoy, V., Qi, Y., Santos, R.A.S., et al. Structure-based identification of small molecule angiotensin converting enzyme 2 activators as novel antihypertensive agents. Hypertension 51 (2008), 1312–1317.
    • (2008) Hypertension , vol.51 , pp. 1312-1317
    • Prada, J.A.H.1    Ferreira, A.J.2    Katovich, M.J.3    Shenoy, V.4    Qi, Y.5    Santos, R.A.S.6
  • 49
  • 50
    • 63049116186 scopus 로고    scopus 로고
    • Tripeptides from dietary proteins inhibit TNF alpha-induced monocyte adhesion to human aortic endothelial cells
    • Ringseis, R., Gotze, V., Eder, K., Tripeptides from dietary proteins inhibit TNF alpha-induced monocyte adhesion to human aortic endothelial cells. Regulatory Peptides 154 (2009), 91–96.
    • (2009) Regulatory Peptides , vol.154 , pp. 91-96
    • Ringseis, R.1    Gotze, V.2    Eder, K.3
  • 53
    • 42149112825 scopus 로고    scopus 로고
    • Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: An integrated view in humans
    • Sarzani, R., Salvi, F., Dessi-Fulgheri, P., Rappelli, A., Renin-angiotensin system, natriuretic peptides, obesity, metabolic syndrome, and hypertension: An integrated view in humans. Journal of Hypertension 26 (2008), 831–843.
    • (2008) Journal of Hypertension , vol.26 , pp. 831-843
    • Sarzani, R.1    Salvi, F.2    Dessi-Fulgheri, P.3    Rappelli, A.4
  • 54
    • 2442513360 scopus 로고    scopus 로고
    • Inflammation and endothelial dysfunction: Intimate companions in the pathogenesis of vascular disease?
    • Sattar, N., Inflammation and endothelial dysfunction: Intimate companions in the pathogenesis of vascular disease?. Clinical Science 106 (2004), 443–445.
    • (2004) Clinical Science , vol.106 , pp. 443-445
    • Sattar, N.1
  • 55
    • 2342567868 scopus 로고    scopus 로고
    • Oxidative stress, antioxidants, and endothelial function
    • Schulz, E., Anter, E., Keaney, J.F. Jr., Oxidative stress, antioxidants, and endothelial function. Current Medicinal Chemistry 11 (2004), 1093–1104.
    • (2004) Current Medicinal Chemistry , vol.11 , pp. 1093-1104
    • Schulz, E.1    Anter, E.2    Keaney, J.F.3
  • 56
    • 79958132625 scopus 로고    scopus 로고
    • Oxidative stress and endothelial dysfunction in hypertension
    • Schulz, E., Gori, T., Münzel, T., Oxidative stress and endothelial dysfunction in hypertension. Hypertension Research 34 (2011), 665–673.
    • (2011) Hypertension Research , vol.34 , pp. 665-673
    • Schulz, E.1    Gori, T.2    Münzel, T.3
  • 58
    • 0037008465 scopus 로고    scopus 로고
    • α-lactorphin and β-lactorphin improve arterial function in spontaneously hypertensive rats
    • Sipola, M., Finchenberg, P., Vapaatalo, H., Korhonen, H., Nurminen, M.L., α-lactorphin and β-lactorphin improve arterial function in spontaneously hypertensive rats. Life Sciences 71 (2002), 1245–1253.
    • (2002) Life Sciences , vol.71 , pp. 1245-1253
    • Sipola, M.1    Finchenberg, P.2    Vapaatalo, H.3    Korhonen, H.4    Nurminen, M.L.5
  • 59
    • 84856032752 scopus 로고    scopus 로고
    • Food protein-derived bioactive peptides: Production, processing, and potential health benefits
    • Udenigwe, C.C., Aluko, R.E., Food protein-derived bioactive peptides: Production, processing, and potential health benefits. Journal of Food Science 77 (2012), R11–R24.
    • (2012) Journal of Food Science , vol.77 , pp. R11-R24
    • Udenigwe, C.C.1    Aluko, R.E.2
  • 60
    • 84899908460 scopus 로고    scopus 로고
    • Mechanisms of food protein-derived antihypertensive peptides other than ACE inhibition
    • Udenigwe, C.C., Mohan, A., Mechanisms of food protein-derived antihypertensive peptides other than ACE inhibition. Journal of Functional Foods 8 (2014), 45–52.
    • (2014) Journal of Functional Foods , vol.8 , pp. 45-52
    • Udenigwe, C.C.1    Mohan, A.2
  • 61
    • 83755178244 scopus 로고    scopus 로고
    • Chemical modifications of peptides and their impact on food properties
    • Van Lancker, F., Adams, A., De Kimpe, N., Chemical modifications of peptides and their impact on food properties. Chemical Reviews 111 (2011), 7876–7903.
    • (2011) Chemical Reviews , vol.111 , pp. 7876-7903
    • Van Lancker, F.1    Adams, A.2    De Kimpe, N.3
  • 62
    • 0024360030 scopus 로고
    • Endothelium and control of vascular function: State of the art lecture
    • Vanhoutte, P.M., Endothelium and control of vascular function: State of the art lecture. Hypertension 13 (1989), 658–667.
    • (1989) Hypertension , vol.13 , pp. 658-667
    • Vanhoutte, P.M.1
  • 63
    • 6944221879 scopus 로고    scopus 로고
    • Bioavailability of angiotensin I converting enzyme inhibitory peptides
    • Vermeirssen, V., Van Camp, J., Verstraete, W., Bioavailability of angiotensin I converting enzyme inhibitory peptides. British Journal of Nutrition 92 (2004), 357–366.
    • (2004) British Journal of Nutrition , vol.92 , pp. 357-366
    • Vermeirssen, V.1    Van Camp, J.2    Verstraete, W.3
  • 64
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme related carboxypeptidase
    • Vickers, C., Hales, P., Kaushik, V., Dick, L., Gavin, J., Tang, J., et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme related carboxypeptidase. The Journal of Biological Chemistry 277 (2002), 14838–14843.
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3    Dick, L.4    Gavin, J.5    Tang, J.6
  • 65
    • 70349084110 scopus 로고    scopus 로고
    • Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis
    • Yamaguchi, N., Kawaguchi, K., Yamamoto, N., Study of the mechanism of antihypertensive peptides VPP and IPP in spontaneously hypertensive rats by DNA microarray analysis. European Journal Pharmacology 620 (2009), 71–77.
    • (2009) European Journal Pharmacology , vol.620 , pp. 71-77
    • Yamaguchi, N.1    Kawaguchi, K.2    Yamamoto, N.3
  • 66
    • 84878015222 scopus 로고    scopus 로고
    • Effects of enalapril on the expression of cardiac angiotensin-converting enzyme and angiotensin-converting enzyme 2 in spontaneously hypertensive rats
    • Yang, Z., Yu, X., Cheng, L., Miao, L., Li, H., Han, L., et al. Effects of enalapril on the expression of cardiac angiotensin-converting enzyme and angiotensin-converting enzyme 2 in spontaneously hypertensive rats. Archives of Cardiovascular Diseases 106 (2013), 196–201.
    • (2013) Archives of Cardiovascular Diseases , vol.106 , pp. 196-201
    • Yang, Z.1    Yu, X.2    Cheng, L.3    Miao, L.4    Li, H.5    Han, L.6
  • 69
    • 12344266754 scopus 로고    scopus 로고
    • TNF-alpha induces interleukin-8 and endothelin-1 expression in human endothelial cells with different redox pathways
    • Zhao, R.Z., Chen, X., Yao, Q., Chen, C., TNF-alpha induces interleukin-8 and endothelin-1 expression in human endothelial cells with different redox pathways. Biochemical and Biophysical Research Communications 327 (2005), 985–992.
    • (2005) Biochemical and Biophysical Research Communications , vol.327 , pp. 985-992
    • Zhao, R.Z.1    Chen, X.2    Yao, Q.3    Chen, C.4
  • 70
    • 77955981900 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction
    • Zhong, J., Basu, R., Guo, D., Chow, F.L., Byrns, S., Schuster, M., et al. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation 122 (2010), 717–728.
    • (2010) Circulation , vol.122 , pp. 717-728
    • Zhong, J.1    Basu, R.2    Guo, D.3    Chow, F.L.4    Byrns, S.5    Schuster, M.6
  • 71
    • 9644258509 scopus 로고    scopus 로고
    • Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acids in spontaneously hypertensive rats
    • Zhong, J., Huang, D., Yang, Y., Li, Y., Liu, G., Song, H., et al. Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acids in spontaneously hypertensive rats. Hypertension 44 (2004), 907–912.
    • (2004) Hypertension , vol.44 , pp. 907-912
    • Zhong, J.1    Huang, D.2    Yang, Y.3    Li, Y.4    Liu, G.5    Song, H.6
  • 72
    • 78650170861 scopus 로고    scopus 로고
    • Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression
    • Zhong, J., Ye, J., Jin, H., Yu, X., Yu, H., Zhu, D., et al. Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression. Regulatory Peptides 166 (2011), 90–97.
    • (2011) Regulatory Peptides , vol.166 , pp. 90-97
    • Zhong, J.1    Ye, J.2    Jin, H.3    Yu, X.4    Yu, H.5    Zhu, D.6
  • 73
    • 84890263719 scopus 로고    scopus 로고
    • New frontiers in the intrarenal renin-angiotensin system: A critical review of classical and new paradigms
    • Zhuo, J.L., Ferrao, F.M., Zheng, Y., Li, X.C., New frontiers in the intrarenal renin-angiotensin system: A critical review of classical and new paradigms. Frontiers in Endocrinology, 4, 2013, 166.
    • (2013) Frontiers in Endocrinology , vol.4 , pp. 166
    • Zhuo, J.L.1    Ferrao, F.M.2    Zheng, Y.3    Li, X.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.