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Volumn 73, Issue 3, 2007, Pages 463-469

ACE2 of the heart: From angiotensin I to angiotensin (1-7)

Author keywords

ACE; ACE2; Angiotensin (1 7); Angiotensin II; Heart

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN[1-7]; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE 2; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LENTIVIRUS VECTOR; LISINOPRIL; LOSARTAN; MINERALOCORTICOID ANTAGONIST; MINERALOCORTICOID RECEPTOR; OLMESARTAN; RENIN; UNCLASSIFIED DRUG;

EID: 33846256550     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2006.09.006     Document Type: Review
Times cited : (214)

References (67)
  • 2
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    • Donoghue M., Hsieh F., Baronas E., Godbout K., Gosselin M., Stagliano N., et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 87 (2000) E1-E9
    • (2000) Circ Res , vol.87
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3    Godbout, K.4    Gosselin, M.5    Stagliano, N.6
  • 3
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • Tipnis S.R., Hooper N.M., Hyde R., Karran E., Christie G., and Turner A.J. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 275 (2000) 33238-33243
    • (2000) J Biol Chem , vol.275 , pp. 33238-33243
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3    Karran, E.4    Christie, G.5    Turner, A.J.6
  • 6
    • 0025598309 scopus 로고
    • Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart
    • Urata H., Kinoshita A., Misono K.S., Bumpus F.M., and Husain A. Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. J Biol Chem 265 (1990) 22348-22357
    • (1990) J Biol Chem , vol.265 , pp. 22348-22357
    • Urata, H.1    Kinoshita, A.2    Misono, K.S.3    Bumpus, F.M.4    Husain, A.5
  • 7
    • 0031283349 scopus 로고    scopus 로고
    • The renin-angiotensin system and vascular function: the role of angiotensin II, angiotensin-converting enzyme, and alternative conversion of angiotensin I
    • Roks A.J.M., Buikema H., Pinto Y.M., and van Gilst W.H. The renin-angiotensin system and vascular function: the role of angiotensin II, angiotensin-converting enzyme, and alternative conversion of angiotensin I. Heart Vessels suppl 12 (1997) 119-124
    • (1997) Heart Vessels , vol.SUPPL. 12 , pp. 119-124
    • Roks, A.J.M.1    Buikema, H.2    Pinto, Y.M.3    van Gilst, W.H.4
  • 8
    • 22744435012 scopus 로고    scopus 로고
    • Serine proteases and cardiac function
    • Wu Q., Kuo H.C., and Deng G.G. Serine proteases and cardiac function. Biochim Biophys Acta 1751 (2005) 82-94
    • (2005) Biochim Biophys Acta , vol.1751 , pp. 82-94
    • Wu, Q.1    Kuo, H.C.2    Deng, G.G.3
  • 9
    • 0037675052 scopus 로고    scopus 로고
    • The role of angiotensin II in regulating vascular structural and functional changes in hypertension
    • Touyz R.M. The role of angiotensin II in regulating vascular structural and functional changes in hypertension. Curr Hypertens Rep 5 (2003) 155-164
    • (2003) Curr Hypertens Rep , vol.5 , pp. 155-164
    • Touyz, R.M.1
  • 10
    • 0026083978 scopus 로고
    • Angiotensin and cell growth: a link to cardiovascular hypertrophy?
    • Schelling P., Fischer H., and Ganten D. Angiotensin and cell growth: a link to cardiovascular hypertrophy?. J Hypertens 9 (1991) 3-15
    • (1991) J Hypertens , vol.9 , pp. 3-15
    • Schelling, P.1    Fischer, H.2    Ganten, D.3
  • 11
    • 0344304669 scopus 로고    scopus 로고
    • Redox-dependent signaling by angiotensin II and vascular remodeling in hypertension
    • Touyz R.M., Tabet F., and Schiffrin E.L. Redox-dependent signaling by angiotensin II and vascular remodeling in hypertension. Clin Exp Pharmacol Physiol 30 (2003) 860-866
    • (2003) Clin Exp Pharmacol Physiol , vol.30 , pp. 860-866
    • Touyz, R.M.1    Tabet, F.2    Schiffrin, E.L.3
  • 12
    • 0035912117 scopus 로고    scopus 로고
    • Angiotensin, fibrinolysis, and vascular homeostasis
    • Vaughan D.E. Angiotensin, fibrinolysis, and vascular homeostasis. Am J Cardiol 19 87 (2001) 18C-24C
    • (2001) Am J Cardiol , vol.19 , Issue.87
    • Vaughan, D.E.1
  • 13
    • 0035383430 scopus 로고    scopus 로고
    • Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors
    • Lijnen P.J., Petrov V.V., and Fagard R.H. Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors. J Renin Angiotensin Aldosterone Syst 2 (2001) 117-122
    • (2001) J Renin Angiotensin Aldosterone Syst , vol.2 , pp. 117-122
    • Lijnen, P.J.1    Petrov, V.V.2    Fagard, R.H.3
  • 14
    • 0032004934 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects
    • Masaki H., Kurihara T., Yamaki A., Inomata N., Nozawa Y., Mori Y., et al. Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects. J Clin Invest 101 (1998) 527-535
    • (1998) J Clin Invest , vol.101 , pp. 527-535
    • Masaki, H.1    Kurihara, T.2    Yamaki, A.3    Inomata, N.4    Nozawa, Y.5    Mori, Y.6
  • 15
    • 0033031543 scopus 로고    scopus 로고
    • Recent progress in angiotensin II type 2 receptor research in the cardiovascular system
    • Horiuchi M., Akishita M., and Dzau V.J. Recent progress in angiotensin II type 2 receptor research in the cardiovascular system. Hypertension 33 (1999) 613-621
    • (1999) Hypertension , vol.33 , pp. 613-621
    • Horiuchi, M.1    Akishita, M.2    Dzau, V.J.3
  • 16
    • 23944519605 scopus 로고    scopus 로고
    • How to explain the differences between renin angiotensin system modulators
    • Levy B.I. How to explain the differences between renin angiotensin system modulators. Am J Hypertens 18 (2005) 134S-141S
    • (2005) Am J Hypertens , vol.18
    • Levy, B.I.1
  • 17
    • 0035843893 scopus 로고    scopus 로고
    • Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function
    • Serneri G.G., Boddi M., Cecioni I., Vanni S., Coppo M., Papa M.L., et al. Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function. Circ Res 88 (2001) 961-968
    • (2001) Circ Res , vol.88 , pp. 961-968
    • Serneri, G.G.1    Boddi, M.2    Cecioni, I.3    Vanni, S.4    Coppo, M.5    Papa, M.L.6
  • 18
    • 0037390060 scopus 로고    scopus 로고
    • Alteration in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure
    • Kaicimi R., and Gerdes A.M. Alteration in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure. Hypertension 41 (2003) 968-977
    • (2003) Hypertension , vol.41 , pp. 968-977
    • Kaicimi, R.1    Gerdes, A.M.2
  • 19
    • 18544378161 scopus 로고    scopus 로고
    • Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
    • Vickers C., Hales P., Kaushik V., Dick L., Gavin J., Tang J., et al. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 277 (2002) 14838-14843
    • (2002) J Biol Chem , vol.277 , pp. 14838-14843
    • Vickers, C.1    Hales, P.2    Kaushik, V.3    Dick, L.4    Gavin, J.5    Tang, J.6
  • 20
    • 33646153057 scopus 로고    scopus 로고
    • A place in our hearts for the lowly angiotensin 1-7 peptide?
    • Reudelhuber T.L. A place in our hearts for the lowly angiotensin 1-7 peptide?. Hypertension 47 (2006) 811-815
    • (2006) Hypertension , vol.47 , pp. 811-815
    • Reudelhuber, T.L.1
  • 21
    • 6344246036 scopus 로고    scopus 로고
    • Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
    • Rice G.I., Thomas D.A., Grant P.J., Turner A.J., and Hooper N.M. Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochem J 383 (2004) 45-51
    • (2004) Biochem J , vol.383 , pp. 45-51
    • Rice, G.I.1    Thomas, D.A.2    Grant, P.J.3    Turner, A.J.4    Hooper, N.M.5
  • 22
    • 0141988865 scopus 로고    scopus 로고
    • Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2
    • Zisman L.S., Keller R.S., Weaver B., Lin Q., Speth R., Bristow M.R., et al. Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2. Circulation 108 (2003) 1707-1712
    • (2003) Circulation , vol.108 , pp. 1707-1712
    • Zisman, L.S.1    Keller, R.S.2    Weaver, B.3    Lin, Q.4    Speth, R.5    Bristow, M.R.6
  • 23
    • 27644585370 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
    • Keidar S., Gamliel-Lazarovich A., Kaplan M., Pavlotzky E., Hamoud S., Hayek T., et al. Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. Circ Res 97 (2005) 946-953
    • (2005) Circ Res , vol.97 , pp. 946-953
    • Keidar, S.1    Gamliel-Lazarovich, A.2    Kaplan, M.3    Pavlotzky, E.4    Hamoud, S.5    Hayek, T.6
  • 24
    • 33750589885 scopus 로고    scopus 로고
    • Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat
    • Ocaranza M.P., Godoy I., Jalil J.E., Varas M., Collantes P., Pinto M., et al. Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat. Hypertension 48 (2006) 572-578
    • (2006) Hypertension , vol.48 , pp. 572-578
    • Ocaranza, M.P.1    Godoy, I.2    Jalil, J.E.3    Varas, M.4    Collantes, P.5    Pinto, M.6
  • 25
    • 12144277081 scopus 로고    scopus 로고
    • The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules
    • Li N., Zimpelmann J., Cheng K., Wilkins J.A., and Burns K.D. The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules. Am J Physiol Renal Physiol 288 (2005) F353-F362
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Li, N.1    Zimpelmann, J.2    Cheng, K.3    Wilkins, J.A.4    Burns, K.D.5
  • 26
    • 33846241330 scopus 로고    scopus 로고
    • Angiotensin metabolism in renal proximal tubules, urine and serum of sheep: evidence for ACE2-dependent processing of angiotensin II
    • [Electronic publication ahead of print]
    • Shaltout H.A., Westwood B., Averill D.B., Ferrario C.M., Figueroa J., Diz D.I., et al. Angiotensin metabolism in renal proximal tubules, urine and serum of sheep: evidence for ACE2-dependent processing of angiotensin II. Am J Physiol Renal Physiol (Aug 8 2006) [Electronic publication ahead of print]
    • (2006) Am J Physiol Renal Physiol
    • Shaltout, H.A.1    Westwood, B.2    Averill, D.B.3    Ferrario, C.M.4    Figueroa, J.5    Diz, D.I.6
  • 28
    • 0026605307 scopus 로고
    • In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats
    • Yamamoto K., Chappell M.C., Brosnihan K.B., and Ferrario C.M. In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats. Hypertension 19 (1992) 692-696
    • (1992) Hypertension , vol.19 , pp. 692-696
    • Yamamoto, K.1    Chappell, M.C.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 29
    • 0028631453 scopus 로고
    • Conversion of angiotensin I to angiotensin-(1-7) by thimet oligopeptidase (EC 3.4.24.15) in vascular smooth muscle cells
    • Chappell M.C., Tallant E.A., Brosnihan K.B., and Ferrario C.M. Conversion of angiotensin I to angiotensin-(1-7) by thimet oligopeptidase (EC 3.4.24.15) in vascular smooth muscle cells. J Vasc Med Biol 5 (1994) 129-137
    • (1994) J Vasc Med Biol , vol.5 , pp. 129-137
    • Chappell, M.C.1    Tallant, E.A.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 32
    • 33644653008 scopus 로고    scopus 로고
    • Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart
    • Castro C.H., Santos R.A., Ferreira A.J., Bader M., Alenina N., and Almeida A.P. Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart. Hypertension 46 (2005) 937-942
    • (2005) Hypertension , vol.46 , pp. 937-942
    • Castro, C.H.1    Santos, R.A.2    Ferreira, A.J.3    Bader, M.4    Alenina, N.5    Almeida, A.P.6
  • 34
    • 0030844113 scopus 로고    scopus 로고
    • Angiotensin-(1-7) and the rat aorta: modulation by the endothelium
    • Le Tran Y., and Forster C. Angiotensin-(1-7) and the rat aorta: modulation by the endothelium. J Cardiovasc Pharmacol 30 (1997) 676-682
    • (1997) J Cardiovasc Pharmacol , vol.30 , pp. 676-682
    • Le Tran, Y.1    Forster, C.2
  • 35
    • 4243617032 scopus 로고    scopus 로고
    • Vasodilator action of angiotensin 1-7 (Ang 1-7) in the isolated afferent arteriole of the rabbit kidney
    • Ren Y., Garvin J.L., and Carretero O.A. Vasodilator action of angiotensin 1-7 (Ang 1-7) in the isolated afferent arteriole of the rabbit kidney. J Am Soc Nephrol 9 (1998) 345A
    • (1998) J Am Soc Nephrol , vol.9
    • Ren, Y.1    Garvin, J.L.2    Carretero, O.A.3
  • 37
    • 0034028647 scopus 로고    scopus 로고
    • Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man
    • Ueda S., Masumori-Maemoto S., Ashino K., Nagahara T., Gotoh E., Umemura S., et al. Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man. Hypertension 35 (2000) 998-1001
    • (2000) Hypertension , vol.35 , pp. 998-1001
    • Ueda, S.1    Masumori-Maemoto, S.2    Ashino, K.3    Nagahara, T.4    Gotoh, E.5    Umemura, S.6
  • 38
    • 0032888404 scopus 로고    scopus 로고
    • Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor
    • Davie A.P., and McMurray J.J. Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor. Hypertension 34 (1999) 457-460
    • (1999) Hypertension , vol.34 , pp. 457-460
    • Davie, A.P.1    McMurray, J.J.2
  • 39
    • 0028560423 scopus 로고
    • Angiotensin(1-7) is an antagonist at the type 1 angiotensin II receptor
    • Mahon J.M., Carr R.D., Nicol A.K., and Henderson I.W. Angiotensin(1-7) is an antagonist at the type 1 angiotensin II receptor. J Hypertens 12 (1994) 1377-1381
    • (1994) J Hypertens , vol.12 , pp. 1377-1381
    • Mahon, J.M.1    Carr, R.D.2    Nicol, A.K.3    Henderson, I.W.4
  • 40
    • 0028275331 scopus 로고
    • Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor
    • Pörsti I., Bara A., Busse R., and Hecker M. Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor. Br J Pharmacol 111 (1994) 652-654
    • (1994) Br J Pharmacol , vol.111 , pp. 652-654
    • Pörsti, I.1    Bara, A.2    Busse, R.3    Hecker, M.4
  • 41
    • 0029926375 scopus 로고    scopus 로고
    • Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide
    • Brosnihan K.B., Li P., and Ferrario C.M. Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide. Hypertension 27 (1996) 523-528
    • (1996) Hypertension , vol.27 , pp. 523-528
    • Brosnihan, K.B.1    Li, P.2    Ferrario, C.M.3
  • 42
    • 0028822339 scopus 로고
    • Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats
    • Paula R.D., Lima C.V., Khosla M.C., and Santos R.A. Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats. Hypertension 26 (1995) 1154-1159
    • (1995) Hypertension , vol.26 , pp. 1154-1159
    • Paula, R.D.1    Lima, C.V.2    Khosla, M.C.3    Santos, R.A.4
  • 46
    • 0141988867 scopus 로고    scopus 로고
    • Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate
    • Zisman L.S., Meixell G.E., Bristow M.R., and Canver C.C. Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate. Circulation 108 (2003) 1679-1681
    • (2003) Circulation , vol.108 , pp. 1679-1681
    • Zisman, L.S.1    Meixell, G.E.2    Bristow, M.R.3    Canver, C.C.4
  • 47
    • 0025098451 scopus 로고
    • The renin-angiotensin system during acute myocardial ischemia in dogs
    • [Suppl]
    • Santos R.A., Brum J.M., Brosnihan K.B., and Ferrario C.M. The renin-angiotensin system during acute myocardial ischemia in dogs. Hypertension 15 (1990) I121-I127 [Suppl]
    • (1990) Hypertension , vol.15
    • Santos, R.A.1    Brum, J.M.2    Brosnihan, K.B.3    Ferrario, C.M.4
  • 49
    • 0037007055 scopus 로고    scopus 로고
    • Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats
    • Loot A.E., Roks A.J., Henning R.H., Tio R.A., Suurmeijer A.J., Boomsma F., et al. Angiotensin-(1-7) attenuates the development of heart failure after myocardial infarction in rats. Circulation 105 (2002) 1548-1550
    • (2002) Circulation , vol.105 , pp. 1548-1550
    • Loot, A.E.1    Roks, A.J.2    Henning, R.H.3    Tio, R.A.4    Suurmeijer, A.J.5    Boomsma, F.6
  • 50
    • 33646161714 scopus 로고    scopus 로고
    • Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice
    • Santos R.A., Castro C.H., Gava E., Pinheiro S.V., Almeida A.P., Paula R.D., et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension 47 (2006) 996-1002
    • (2006) Hypertension , vol.47 , pp. 996-1002
    • Santos, R.A.1    Castro, C.H.2    Gava, E.3    Pinheiro, S.V.4    Almeida, A.P.5    Paula, R.D.6
  • 51
    • 21344442672 scopus 로고    scopus 로고
    • Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure
    • Kittleson M.M., Minhas K.M., Irizarry R.A., Ye S.Q., Edness G., Breton E., et al. Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure. Physiol Genomics 21 (2005) 299-307
    • (2005) Physiol Genomics , vol.21 , pp. 299-307
    • Kittleson, M.M.1    Minhas, K.M.2    Irizarry, R.A.3    Ye, S.Q.4    Edness, G.5    Breton, E.6
  • 52
    • 30744445980 scopus 로고    scopus 로고
    • Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy
    • Lieb W., Graf J., Gotz A., Konig I.R., Mayer B., Fischer M., et al. Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy. J Mol Med 84 (2006) 88-96
    • (2006) J Mol Med , vol.84 , pp. 88-96
    • Lieb, W.1    Graf, J.2    Gotz, A.3    Konig, I.R.4    Mayer, B.5    Fischer, M.6
  • 54
    • 2342620869 scopus 로고    scopus 로고
    • Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors
    • Ishiyama Y., Gallagher P.E., Averill D.B., Tallant E.A., Brosnihan K.B., and Ferrario C.M. Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors. Hypertension 43 (2004) 970-976
    • (2004) Hypertension , vol.43 , pp. 970-976
    • Ishiyama, Y.1    Gallagher, P.E.2    Averill, D.B.3    Tallant, E.A.4    Brosnihan, K.B.5    Ferrario, C.M.6
  • 55
    • 0037142101 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is an essential regulator of heart function
    • Crackower M.A., Sarao R., Oudit G.Y., Yagil C., Kozieradzki I., Scanga S.E., et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417 (2002) 822-828
    • (2002) Nature , vol.417 , pp. 822-828
    • Crackower, M.A.1    Sarao, R.2    Oudit, G.Y.3    Yagil, C.4    Kozieradzki, I.5    Scanga, S.E.6
  • 56
    • 33645834948 scopus 로고    scopus 로고
    • Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
    • Yamamoto K., Ohishi M., Katsuya T., Ito N., Ikushima M., Kaibe M., et al. Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension 47 (2006) 718-726
    • (2006) Hypertension , vol.47 , pp. 718-726
    • Yamamoto, K.1    Ohishi, M.2    Katsuya, T.3    Ito, N.4    Ikushima, M.5    Kaibe, M.6
  • 57
    • 0037048716 scopus 로고    scopus 로고
    • Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors
    • Dales N.A., Gould A.E., Brown J.A., Calderwood E.F., Guan B., Minor C.A., et al. Substrate-based design of the first class of angiotensin-converting enzyme-related carboxypeptidase (ACE2) inhibitors. J Am Chem Soc 124 (2002) 11852-11853
    • (2002) J Am Chem Soc , vol.124 , pp. 11852-11853
    • Dales, N.A.1    Gould, A.E.2    Brown, J.A.3    Calderwood, E.F.4    Guan, B.5    Minor, C.A.6
  • 60
    • 2342472108 scopus 로고    scopus 로고
    • Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?
    • Ye M., Wysocki J., Naaz P., Salabat M.R., LaPointe M.S., and Batlle D. Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?. Hypertension 43 (2004) 1120-1125
    • (2004) Hypertension , vol.43 , pp. 1120-1125
    • Ye, M.1    Wysocki, J.2    Naaz, P.3    Salabat, M.R.4    LaPointe, M.S.5    Batlle, D.6
  • 61
    • 10744223104 scopus 로고    scopus 로고
    • Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins
    • Donoghue M., Wakimoto H., Maguire C.T., Acton S., Hales P., Stagliano N., et al. Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. J Mol Cell Cardiol 35 9 (Sep 2003) 1043-1053
    • (2003) J Mol Cell Cardiol , vol.35 , Issue.9 , pp. 1043-1053
    • Donoghue, M.1    Wakimoto, H.2    Maguire, C.T.3    Acton, S.4    Hales, P.5    Stagliano, N.6
  • 62
    • 3242769868 scopus 로고    scopus 로고
    • Interaction of ACE2 and integrin beta 1 in failing human heart
    • Lin Q., Keller R.S., Weaver B., and Zisman L.S. Interaction of ACE2 and integrin beta 1 in failing human heart. Biochim Biophys Acta 1689 (2004) 175-178
    • (2004) Biochim Biophys Acta , vol.1689 , pp. 175-178
    • Lin, Q.1    Keller, R.S.2    Weaver, B.3    Zisman, L.S.4
  • 63
    • 26044453206 scopus 로고    scopus 로고
    • Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats
    • Huentelman M.J., Grobe J.L., Vazquez J., Stewart J.M., Mecca A.P., Katovich M.J., et al. Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats. Exp Physiol 90 (2005) 783-790
    • (2005) Exp Physiol , vol.90 , pp. 783-790
    • Huentelman, M.J.1    Grobe, J.L.2    Vazquez, J.3    Stewart, J.M.4    Mecca, A.P.5    Katovich, M.J.6
  • 64
    • 0027379394 scopus 로고
    • Hemodynamic and neurohormonal effects of the angiotensin II antagonist losartan in patients with congestive heart failure
    • Gottlieb S.S., Dickstein K., Fleck E., Kostis J., Levine T.B., LeJemtel T., et al. Hemodynamic and neurohormonal effects of the angiotensin II antagonist losartan in patients with congestive heart failure. Circulation 88 (1993) 1602-1609
    • (1993) Circulation , vol.88 , pp. 1602-1609
    • Gottlieb, S.S.1    Dickstein, K.2    Fleck, E.3    Kostis, J.4    Levine, T.B.5    LeJemtel, T.6
  • 65
    • 0031601350 scopus 로고    scopus 로고
    • Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system
    • Iyer S.N., Ferrario C.M., and Chappell M.C. Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension 31 (1998) 356-361
    • (1998) Hypertension , vol.31 , pp. 356-361
    • Iyer, S.N.1    Ferrario, C.M.2    Chappell, M.C.3
  • 66
    • 19644384705 scopus 로고    scopus 로고
    • Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
    • Ferrario C.M., Jessup J., Chappell M.C., Averill D.B., Brosnihan K.B., Tallant E.A., et al. Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 111 (2005) 2605-2610
    • (2005) Circulation , vol.111 , pp. 2605-2610
    • Ferrario, C.M.1    Jessup, J.2    Chappell, M.C.3    Averill, D.B.4    Brosnihan, K.B.5    Tallant, E.A.6
  • 67
    • 23944472129 scopus 로고    scopus 로고
    • Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats
    • Igase M., Strawn W.B., Gallagher P.E., Geary R.L., and Ferrario C.M. Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 289 (2005) H1013-H1019
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Igase, M.1    Strawn, W.B.2    Gallagher, P.E.3    Geary, R.L.4    Ferrario, C.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.