-
1
-
-
33644860787
-
Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with l-NAME
-
Benter IF, Yousif MH, Anim JT, Cojocel C & Diz DI (2006). Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with l-NAME. Am J Physiol Heart Circ Physiol 290, H684-H691.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Benter, I.F.1
Yousif, M.H.2
Anim, J.T.3
Cojocel, C.4
Diz, D.I.5
-
2
-
-
0036173992
-
Studies of prevention, treatment and mechanisms of heart failure in the aging spontaneously hypertensive rat
-
Bing OH, Conrad CH, Boluyt MO, Robinson KG & Brooks WW (2002). Studies of prevention, treatment and mechanisms of heart failure in the aging spontaneously hypertensive rat. Heart Fail Rev 7, 71-88.
-
(2002)
Heart Fail Rev
, vol.7
, pp. 71-88
-
-
Bing, O.H.1
Conrad, C.H.2
Boluyt, M.O.3
Robinson, K.G.4
Brooks, W.W.5
-
3
-
-
79958820082
-
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit
-
Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, Guo D, Holland SM, Scholey JW, Penninger JM, Kassiri Z & Oudit GY (2011). Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit. Cardiovasc Res 91, 151-161.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 151-161
-
-
Bodiga, S.1
Zhong, J.C.2
Wang, W.3
Basu, R.4
Lo, J.5
Liu, G.C.6
Guo, D.7
Holland, S.M.8
Scholey, J.W.9
Penninger, J.M.10
Kassiri, Z.11
Oudit, G.Y.12
-
4
-
-
0030657940
-
Effect of angiotensin-converting enzyme inhibition on myocardial fibrosis and function in hypertrophied and failing myocardium from the spontaneously hypertensive rat
-
Brooks WW, Bing OH, Robinson KG, Slawsky MT, Chaletsky DM & Conrad CH (1997). Effect of angiotensin-converting enzyme inhibition on myocardial fibrosis and function in hypertrophied and failing myocardium from the spontaneously hypertensive rat. Circulation 96, 4002-4010.
-
(1997)
Circulation
, vol.96
, pp. 4002-4010
-
-
Brooks, W.W.1
Bing, O.H.2
Robinson, K.G.3
Slawsky, M.T.4
Chaletsky, D.M.5
Conrad, C.H.6
-
5
-
-
0034711753
-
Essential hypertension. Part I: definition and etiology
-
Carretero OA & Oparil S (2000). Essential hypertension. Part I: definition and etiology. Circulation 101, 329-335.
-
(2000)
Circulation
, vol.101
, pp. 329-335
-
-
Carretero, O.A.1
Oparil, S.2
-
6
-
-
0036175986
-
Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney
-
Chabrashvili T, Tojo A, Onozato ML, Kitiyakara C, Quinn MT, Fujita T, Welch WJ & Wilcox CS (2002). Expression and cellular localization of classic NADPH oxidase subunits in the spontaneously hypertensive rat kidney. Hypertension 39, 269-274.
-
(2002)
Hypertension
, vol.39
, pp. 269-274
-
-
Chabrashvili, T.1
Tojo, A.2
Onozato, M.L.3
Kitiyakara, C.4
Quinn, M.T.5
Fujita, T.6
Welch, W.J.7
Wilcox, C.S.8
-
7
-
-
0037142101
-
Angiotensin-converting enzyme 2 is an essential regulator of heart function
-
Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, Da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y & Penninger JM (2002). Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417, 822-828.
-
(2002)
Nature
, vol.417
, pp. 822-828
-
-
Crackower, M.A.1
Sarao, R.2
Oudit, G.Y.3
Yagil, C.4
Kozieradzki, I.5
Scanga, S.E.6
Oliveira-dos-Santos, A.J.7
Da Costa, J.8
Zhang, L.9
Pei, Y.10
Scholey, J.11
Ferrario, C.M.12
Manoukian, A.S.13
Chappell, M.C.14
Backx, P.H.15
Yagil, Y.16
Penninger, J.M.17
-
8
-
-
0036812489
-
Angiotensin II and nitric oxide interaction
-
de Gasparo M (2002). Angiotensin II and nitric oxide interaction. Heart Fail Rev 7, 347-358.
-
(2002)
Heart Fail Rev
, vol.7
, pp. 347-358
-
-
de Gasparo, M.1
-
9
-
-
33344475554
-
ACE2: a novel therapeutic target for cardiovascular diseases
-
Der Sarkissian S, Huentelman MJ, Stewart J, Katovich MJ & Raizada MK (2006). ACE2: a novel therapeutic target for cardiovascular diseases. Prog Biophys Mol Biol 91, 163-198.
-
(2006)
Prog Biophys Mol Biol
, vol.91
, pp. 163-198
-
-
Der Sarkissian, S.1
Huentelman, M.J.2
Stewart, J.3
Katovich, M.J.4
Raizada, M.K.5
-
10
-
-
33749437743
-
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR
-
Díez-Freire C, Vázquez J, Correa de Adjounian MF, Ferrari MF, Yuan L, Silver X, Torres R & Raizada MK (2006). ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics 27, 12-19.
-
(2006)
Physiol Genomics
, vol.27
, pp. 12-19
-
-
Díez-Freire, C.1
Vázquez, J.2
Correa de Adjounian, M.F.3
Ferrari, M.F.4
Yuan, L.5
Silver, X.6
Torres, R.7
Raizada, M.K.8
-
11
-
-
68849105984
-
Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes
-
Epelman S, Shrestha K, Troughton RW, Francis GS, Sen S, Klein AL & Tang WH (2009). Soluble angiotensin-converting enzyme 2 in human heart failure: relation with myocardial function and clinical outcomes. J Card Fail 15, 565-571.
-
(2009)
J Card Fail
, vol.15
, pp. 565-571
-
-
Epelman, S.1
Shrestha, K.2
Troughton, R.W.3
Francis, G.S.4
Sen, S.5
Klein, A.L.6
Tang, W.H.7
-
12
-
-
49349093061
-
Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system
-
Epelman S, Tang WH, Chen SY, Van Lente F, Francis GS & Sen S (2008). Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system. J Am Coll Cardiol 52, 750-754.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 750-754
-
-
Epelman, S.1
Tang, W.H.2
Chen, S.Y.3
Van Lente, F.4
Francis, G.S.5
Sen, S.6
-
13
-
-
41449089986
-
Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation
-
Feng Y, Yue X, Xia H, Bindom SM, Hickman PJ, Filipeanu CM, Wu G & Lazartigues E (2008). Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ Res 102, 729-736.
-
(2008)
Circ Res
, vol.102
, pp. 729-736
-
-
Feng, Y.1
Yue, X.2
Xia, H.3
Bindom, S.M.4
Hickman, P.J.5
Filipeanu, C.M.6
Wu, G.7
Lazartigues, E.8
-
14
-
-
19644384705
-
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
-
Ferrario CM, Jessup J, Chappell MC, Averill DB, Brosnihan KB, Tallant EA, Diz DI & Gallagher PE (2005). Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 111, 2605-2610.
-
(2005)
Circulation
, vol.111
, pp. 2605-2610
-
-
Ferrario, C.M.1
Jessup, J.2
Chappell, M.C.3
Averill, D.B.4
Brosnihan, K.B.5
Tallant, E.A.6
Diz, D.I.7
Gallagher, P.E.8
-
15
-
-
79951509062
-
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases
-
Ferreira AJ, Shenoy V, Qi Y, Fraga-Silva RA, Santos RAS, Katovich MJ & Raizada MK (2011). Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases. Exp Physiol 96, 287-294.
-
(2011)
Exp Physiol
, vol.96
, pp. 287-294
-
-
Ferreira, A.J.1
Shenoy, V.2
Qi, Y.3
Fraga-Silva, R.A.4
Santos, R.A.S.5
Katovich, M.J.6
Raizada, M.K.7
-
17
-
-
73849095442
-
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3′,5′-cyclic monophosphate-dependent pathway
-
Gomes ER, Lara AA, Almeida PW, Guimarães D, Resende RR, Campagnole-Santos MJ, Bader M, Santos RA & Guatimosim S (2010). Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3′, 5′-cyclic monophosphate-dependent pathway. Hypertension 55, 153-160.
-
(2010)
Hypertension
, vol.55
, pp. 153-160
-
-
Gomes, E.R.1
Lara, A.A.2
Almeida, P.W.3
Guimarães, D.4
Resende, R.R.5
Campagnole-Santos, M.J.6
Bader, M.7
Santos, R.A.8
Guatimosim, S.9
-
18
-
-
0142055950
-
Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS
-
Griendling KK & FitzGerald GA (2003). Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation 108, 1912-1916.
-
(2003)
Circulation
, vol.108
, pp. 1912-1916
-
-
Griendling, K.K.1
FitzGerald, G.A.2
-
19
-
-
0028365310
-
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
-
Griendling KK, Minieri CA, Ollerenshaw JD & Alexander RW (1994). Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 74, 1141-1148.
-
(1994)
Circ Res
, vol.74
, pp. 1141-1148
-
-
Griendling, K.K.1
Minieri, C.A.2
Ollerenshaw, J.D.3
Alexander, R.W.4
-
20
-
-
0034677947
-
NAD(P)H oxidase: role in cardiovascular biology and disease
-
Griendling KK, Sorescu D & Ushio-Fukai M (2000). NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86, 494-501.
-
(2000)
Circ Res
, vol.86
, pp. 494-501
-
-
Griendling, K.K.1
Sorescu, D.2
Ushio-Fukai, M.3
-
21
-
-
42349105833
-
Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents
-
Hernández Prada JA, Ferreira AJ, Katovich MJ, Shenoy V, Qi Y, Santos RA, Castellano RK, Lampkins AJ, Gubala V, Ostrov DA & Raizada MK (2008). Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension 51, 1312-1317.
-
(2008)
Hypertension
, vol.51
, pp. 1312-1317
-
-
Hernández Prada, J.A.1
Ferreira, A.J.2
Katovich, M.J.3
Shenoy, V.4
Qi, Y.5
Santos, R.A.6
Castellano, R.K.7
Lampkins, A.J.8
Gubala, V.9
Ostrov, D.A.10
Raizada, M.K.11
-
22
-
-
26044453206
-
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats
-
Huentelman MJ, Grobe JL, Vazquez J, Stewart JM, Mecca AP, Katovich MJ, Ferrario CM & Raizada MK (2005). Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats. Exp Physiol 90, 783-790.
-
(2005)
Exp Physiol
, vol.90
, pp. 783-790
-
-
Huentelman, M.J.1
Grobe, J.L.2
Vazquez, J.3
Stewart, J.M.4
Mecca, A.P.5
Katovich, M.J.6
Ferrario, C.M.7
Raizada, M.K.8
-
23
-
-
21844460785
-
Angiotensin-converting enzyme 2 protects from severe acute lung failure
-
Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C & Penninger JM (2005). Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436, 112-116.
-
(2005)
Nature
, vol.436
, pp. 112-116
-
-
Imai, Y.1
Kuba, K.2
Rao, S.3
Huan, Y.4
Guo, F.5
Guan, B.6
Yang, P.7
Sarao, R.8
Wada, T.9
Leong-Poi, H.10
Crackower, M.A.11
Fukamizu, A.12
Hui, C.C.13
Hein, L.14
Uhlig, S.15
Slutsky, A.S.16
Jiang, C.17
Penninger, J.M.18
-
24
-
-
2342620869
-
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors
-
Ishiyama Y, Gallagher PE, Averill DB, Tallant EA, Brosnihan KB & Ferrario CM (2004). Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors. Hypertension 43, 970-976.
-
(2004)
Hypertension
, vol.43
, pp. 970-976
-
-
Ishiyama, Y.1
Gallagher, P.E.2
Averill, D.B.3
Tallant, E.A.4
Brosnihan, K.B.5
Ferrario, C.M.6
-
25
-
-
18844381161
-
Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertension
-
Katovich MJ, Grobe JL, Huentelman M & Raizada MK (2005). Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertension. Exp Physiol 90, 299-305.
-
(2005)
Exp Physiol
, vol.90
, pp. 299-305
-
-
Katovich, M.J.1
Grobe, J.L.2
Huentelman, M.3
Raizada, M.K.4
-
26
-
-
0034100147
-
Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases
-
Kim S & Iwao H (2000). Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 52, 11-34.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 11-34
-
-
Kim, S.1
Iwao, H.2
-
27
-
-
43449084360
-
Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway
-
Koka V, Huang XR, Chung AC, Wang W, Truong LD & Lan HY (2008). Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway. Am J Pathol 172, 1174-1183.
-
(2008)
Am J Pathol
, vol.172
, pp. 1174-1183
-
-
Koka, V.1
Huang, X.R.2
Chung, A.C.3
Wang, W.4
Truong, L.D.5
Lan, H.Y.6
-
28
-
-
33746616817
-
Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats
-
Lodi F, Cogolludo A, Duarte J, Moreno L, Coviello A, Peral De Bruno M, Vera R, Galisteo M, Jiménez R, Tamargo J & Perez-Vizcaino F (2006). Increased NADPH oxidase activity mediates spontaneous aortic tone in genetically hypertensive rats. Eur J Pharmacol 544, 97-103.
-
(2006)
Eur J Pharmacol
, vol.544
, pp. 97-103
-
-
Lodi, F.1
Cogolludo, A.2
Duarte, J.3
Moreno, L.4
Coviello, A.5
Peral De Bruno, M.6
Vera, R.7
Galisteo, M.8
Jiménez, R.9
Tamargo, J.10
Perez-Vizcaino, F.11
-
29
-
-
0015237841
-
The natural history of congestive heart failure: the Framingham study
-
McKee PA, Castelli WP, McNamara PM & Kannel WB (1971). The natural history of congestive heart failure: the Framingham study. N Engl J Med 285, 1441-1446.
-
(1971)
N Engl J Med
, vol.285
, pp. 1441-1446
-
-
McKee, P.A.1
Castelli, W.P.2
McNamara, P.M.3
Kannel, W.B.4
-
30
-
-
64849108788
-
Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2
-
Masson R, Nicklin SA, Craig MA, McBride M, Gilday K, Gregorevic P, Allen JM, Chamberlain JS, Smith G, Graham D, Dominiczak AF, Napoli C & Baker AH (2009). Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension 53, 694-700.
-
(2009)
Hypertension
, vol.53
, pp. 694-700
-
-
Masson, R.1
Nicklin, S.A.2
Craig, M.A.3
McBride, M.4
Gilday, K.5
Gregorevic, P.6
Allen, J.M.7
Chamberlain, J.S.8
Smith, G.9
Graham, D.10
Dominiczak, A.F.11
Napoli, C.12
Baker, A.H.13
-
31
-
-
33846362954
-
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
-
Mehta PK & Griendling KK (2007). Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292, C82-C97.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Mehta, P.K.1
Griendling, K.K.2
-
32
-
-
58149352445
-
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart
-
Mercure C, Yogi A, Callera GE, Aranha AB, Bader M, Ferreira AJ, Santos RA, Walther T, Touyz RM & Reudelhuber TL (2008). Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart. Circ Res 103, 1319-1326.
-
(2008)
Circ Res
, vol.103
, pp. 1319-1326
-
-
Mercure, C.1
Yogi, A.2
Callera, G.E.3
Aranha, A.B.4
Bader, M.5
Ferreira, A.J.6
Santos, R.A.7
Walther, T.8
Touyz, R.M.9
Reudelhuber, T.L.10
-
33
-
-
42649105447
-
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease
-
Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gosele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC & Hubner N (2008). Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nat Genet 40, 529-537.
-
(2008)
Nat Genet
, vol.40
, pp. 529-537
-
-
Monti, J.1
Fischer, J.2
Paskas, S.3
Heinig, M.4
Schulz, H.5
Gosele, C.6
Heuser, A.7
Fischer, R.8
Schmidt, C.9
Schirdewan, A.10
Gross, V.11
Hummel, O.12
Maatz, H.13
Patone, G.14
Saar, K.15
Vingron, M.16
Weldon, S.M.17
Lindpaintner, K.18
Hammock, B.D.19
Rohde, K.20
Dietz, R.21
Cook, S.A.22
Schunck, W.H.23
Luft, F.C.24
Hubner, N.25
more..
-
34
-
-
84857060387
-
Renal sympathetic activation from long-term low-dose angiotensin II infusion in rabbits
-
Moretti JL, Burke SL, Davern PJ, Evans RG, Lambert GW & Head GA (2012). Renal sympathetic activation from long-term low-dose angiotensin II infusion in rabbits. J Hypertens 30, 551-560.
-
(2012)
J Hypertens
, vol.30
, pp. 551-560
-
-
Moretti, J.L.1
Burke, S.L.2
Davern, P.J.3
Evans, R.G.4
Lambert, G.W.5
Head, G.A.6
-
35
-
-
33744731510
-
Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis
-
Oudit GY, Herzenberg AM, Kassiri Z, Wong D, Reich H, Khokha R, Crackower MA, Backx PH, Penninger JM & Scholey JW (2006). Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis. Am J Pathol 168, 1808-1820.
-
(2006)
Am J Pathol
, vol.168
, pp. 1808-1820
-
-
Oudit, G.Y.1
Herzenberg, A.M.2
Kassiri, Z.3
Wong, D.4
Reich, H.5
Khokha, R.6
Crackower, M.A.7
Backx, P.H.8
Penninger, J.M.9
Scholey, J.W.10
-
36
-
-
77449160523
-
Human recombinant ACE2 reduces the progression of diabetic nephropathy
-
Oudit GY, Liu GC, Zhong J, Basu R, Chow FL, Zhou J, Loibner H, Janzek E, Schuster M, Penninger JM, Herzenberg AM, Kassiri Z & Scholey JW (2010). Human recombinant ACE2 reduces the progression of diabetic nephropathy. Diabetes 59, 529-538.
-
(2010)
Diabetes
, vol.59
, pp. 529-538
-
-
Oudit, G.Y.1
Liu, G.C.2
Zhong, J.3
Basu, R.4
Chow, F.L.5
Zhou, J.6
Loibner, H.7
Janzek, E.8
Schuster, M.9
Penninger, J.M.10
Herzenberg, A.M.11
Kassiri, Z.12
Scholey, J.W.13
-
37
-
-
80055049289
-
Recombinant human angiotensin-converting enzyme 2 as a new renin-angiotensin system peptidase for heart failure therapy
-
Oudit GY & Penninger JM (2011). Recombinant human angiotensin-converting enzyme 2 as a new renin-angiotensin system peptidase for heart failure therapy. Curr Heart Fail Rep 8, 176-183.
-
(2011)
Curr Heart Fail Rep
, vol.8
, pp. 176-183
-
-
Oudit, G.Y.1
Penninger, J.M.2
-
38
-
-
84861099242
-
Loss of Angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis
-
Patel VB, Bodiga S, Basu R, Das SK, Wang W, Wang Z, Lo J, Grant MB, Zhong J, Kassiri Z & Oudit GY (2012a). Loss of Angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axis. Circ Res 110, 1322-1335.
-
(2012)
Circ Res
, vol.110
, pp. 1322-1335
-
-
Patel, V.B.1
Bodiga, S.2
Basu, R.3
Das, S.K.4
Wang, W.5
Wang, Z.6
Lo, J.7
Grant, M.B.8
Zhong, J.9
Kassiri, Z.10
Oudit, G.Y.11
-
39
-
-
84861528870
-
cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice
-
Patel VB, Bodiga S, Fan D, Das SK, Wang Z, Wang W, Basu R, Zhong J, Kassiri Z & Oudit GY (2012b). cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice. Hypertension 59, 1195-1203.
-
(2012)
Hypertension
, vol.59
, pp. 1195-1203
-
-
Patel, V.B.1
Bodiga, S.2
Fan, D.3
Das, S.K.4
Wang, Z.5
Wang, W.6
Basu, R.7
Zhong, J.8
Kassiri, Z.9
Oudit, G.Y.10
-
40
-
-
34547951695
-
ACE2: a new target for cardiovascular disease therapeutics
-
Raizada MK & Ferreira AJ (2007). ACE2: a new target for cardiovascular disease therapeutics. J Cardiovasc Pharmacol 50, 112-119.
-
(2007)
J Cardiovasc Pharmacol
, vol.50
, pp. 112-119
-
-
Raizada, M.K.1
Ferreira, A.J.2
-
41
-
-
0030005713
-
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone
-
Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK & Harrison DG (1996). Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest 97, 1916-1923.
-
(1996)
J Clin Invest
, vol.97
, pp. 1916-1923
-
-
Rajagopalan, S.1
Kurz, S.2
Munzel, T.3
Tarpey, M.4
Freeman, B.A.5
Griendling, K.K.6
Harrison, D.G.7
-
42
-
-
36448975192
-
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells
-
Sampaio WO, Henrique De Castro C, Santos RA, Schiffrin EL & Touyz RM (2007). Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells. Hypertension 50, 1093-1098.
-
(2007)
Hypertension
, vol.50
, pp. 1093-1098
-
-
Sampaio, W.O.1
Henrique De Castro, C.2
Santos, R.A.3
Schiffrin, E.L.4
Touyz, R.M.5
-
43
-
-
25444473110
-
Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor
-
Tallant EA, Ferrario CM & Gallagher PE (2005). Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor. Am J Physiol Heart Circ Physiol 289, H1560-H1566.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Tallant, E.A.1
Ferrario, C.M.2
Gallagher, P.E.3
-
44
-
-
83455195588
-
Regulation of angiotensin-converting enzyme 2 and Mas receptor by Ang-(1-7) in heart and kidney of spontaneously hypertensive rats
-
Tan Z, Wu J & Ma H (2011). Regulation of angiotensin-converting enzyme 2 and Mas receptor by Ang-(1-7) in heart and kidney of spontaneously hypertensive rats. J Renin Angiotensin Aldosterone Syst 12, 413-419.
-
(2011)
J Renin Angiotensin Aldosterone Syst
, vol.12
, pp. 413-419
-
-
Tan, Z.1
Wu, J.2
Ma, H.3
-
45
-
-
0034721906
-
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
-
Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G & Turner AJ (2000). A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 275, 33238-33243.
-
(2000)
J Biol Chem
, vol.275
, pp. 33238-33243
-
-
Tipnis, S.R.1
Hooper, N.M.2
Hyde, R.3
Karran, E.4
Christie, G.5
Turner, A.J.6
-
46
-
-
38349138319
-
Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling
-
Tsai CT, Lai LP, Kuo KT, Hwang JJ, Hsieh CS, Hsu KL, Tseng CD, Tseng YZ, Chiang FT & Lin JL (2008). Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. Circulation 117, 344-355.
-
(2008)
Circulation
, vol.117
, pp. 344-355
-
-
Tsai, C.T.1
Lai, L.P.2
Kuo, K.T.3
Hwang, J.J.4
Hsieh, C.S.5
Hsu, K.L.6
Tseng, C.D.7
Tseng, Y.Z.8
Chiang, F.T.9
Lin, J.L.10
-
47
-
-
77949891096
-
Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction
-
Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE & Ferrario CM (2010). Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Ther Adv Cardiovasc Dis 4, 17-25.
-
(2010)
Ther Adv Cardiovasc Dis
, vol.4
, pp. 17-25
-
-
Varagic, J.1
Ahmad, S.2
Brosnihan, K.B.3
Groban, L.4
Chappell, M.C.5
Tallant, E.A.6
Gallagher, P.E.7
Ferrario, C.M.8
-
48
-
-
18544378161
-
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
-
Vickers C, Hales P, Kaushik V, Dick L, Gavin J, Tang J, Godbout K, Parsons T, Baronas E, Hsieh F, Acton S, Patane M, Nichols A & Tummino P (2002). Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 277, 14838-14843.
-
(2002)
J Biol Chem
, vol.277
, pp. 14838-14843
-
-
Vickers, C.1
Hales, P.2
Kaushik, V.3
Dick, L.4
Gavin, J.5
Tang, J.6
Godbout, K.7
Parsons, T.8
Baronas, E.9
Hsieh, F.10
Acton, S.11
Patane, M.12
Nichols, A.13
Tummino, P.14
-
49
-
-
84862648459
-
Role of ACE2 in diastolic and systolic heart failure
-
Wang W, Bodiga S, Das SK, Lo J, Patel V & Oudit GY (2012). Role of ACE2 in diastolic and systolic heart failure. Heart Fail Rev 17, 683-691.
-
(2012)
Heart Fail Rev
, vol.17
, pp. 683-691
-
-
Wang, W.1
Bodiga, S.2
Das, S.K.3
Lo, J.4
Patel, V.5
Oudit, G.Y.6
-
50
-
-
0025770664
-
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system
-
Weber KT & Brilla CG (1991). Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 83, 1849-1865.
-
(1991)
Circulation
, vol.83
, pp. 1849-1865
-
-
Weber, K.T.1
Brilla, C.G.2
-
51
-
-
0032759357
-
Cardiovascular effects of angiotensin-(1-7) in conscious spontaneously hypertensive rats
-
Widdop RE, Sampey DB & Jarrott B (1999). Cardiovascular effects of angiotensin-(1-7) in conscious spontaneously hypertensive rats. Hypertension 34, 964-968.
-
(1999)
Hypertension
, vol.34
, pp. 964-968
-
-
Widdop, R.E.1
Sampey, D.B.2
Jarrott, B.3
-
52
-
-
77956813371
-
Comparative pharmacology of chemically distinct NADPH oxidase inhibitors
-
Wind S, Beuerlein K, Eucker T, Muller H, Scheurer P, Armitage ME, Ho H, Schmidt HH & Wingler K (2010). Comparative pharmacology of chemically distinct NADPH oxidase inhibitors. Br J Pharmacol 161, 885-898.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 885-898
-
-
Wind, S.1
Beuerlein, K.2
Eucker, T.3
Muller, H.4
Scheurer, P.5
Armitage, M.E.6
Ho, H.7
Schmidt, H.H.8
Wingler, K.9
-
53
-
-
73849101073
-
Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension
-
Wysocki J, Ye M, Rodriguez E, González-Pacheco FR, Barrios C, Evora K, Schuster M, Loibner H, Brosnihan KB, Ferrario CM, Penninger JM & Batlle D (2009). Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension. Hypertension 55, 90-98.
-
(2009)
Hypertension
, vol.55
, pp. 90-98
-
-
Wysocki, J.1
Ye, M.2
Rodriguez, E.3
González-Pacheco, F.R.4
Barrios, C.5
Evora, K.6
Schuster, M.7
Loibner, H.8
Brosnihan, K.B.9
Ferrario, C.M.10
Penninger, J.M.11
Batlle, D.12
-
54
-
-
34047193877
-
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
-
Yamazato M, Yamazato Y, Sun C, Diez-Freire C & Raizada MK (2007). Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension 49, 926-931.
-
(2007)
Hypertension
, vol.49
, pp. 926-931
-
-
Yamazato, M.1
Yamazato, Y.2
Sun, C.3
Diez-Freire, C.4
Raizada, M.K.5
-
55
-
-
79551485466
-
Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2
-
Zhong J, Guo D, Chen CB, Wang W, Schuster M, Loibner H, Penninger JM, Scholey JW, Kassiri Z & Oudit GY (2011a). Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension 57, 314-322.
-
(2011)
Hypertension
, vol.57
, pp. 314-322
-
-
Zhong, J.1
Guo, D.2
Chen, C.B.3
Wang, W.4
Schuster, M.5
Loibner, H.6
Penninger, J.M.7
Scholey, J.W.8
Kassiri, Z.9
Oudit, G.Y.10
-
56
-
-
77955981900
-
Angiotensin converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis and cardiac dysfunction
-
Zhong JC, Basu R, Guo D, Chow FL, Byrns S, Shuster M, Loibner H, Wang X, Penninger JM, Kassiri Z & Oudit GY (2010). Angiotensin converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis and cardiac dysfunction. Circulation 122, 717-728.
-
(2010)
Circulation
, vol.122
, pp. 717-728
-
-
Zhong, J.C.1
Basu, R.2
Guo, D.3
Chow, F.L.4
Byrns, S.5
Shuster, M.6
Loibner, H.7
Wang, X.8
Penninger, J.M.9
Kassiri, Z.10
Oudit, G.Y.11
-
57
-
-
78650170861
-
Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression
-
Zhong JC, Ye JY, Jin HY, Yu X, Yu HM, Zhu DL, Gao PJ, Huang DY, Shuster M, Loibner H, Guo JM, Yu XY, Xiao BX, Gong ZH, Penninger JM & Oudit GY (2011b). Telmisartan attenuates aortic hypertrophy in hypertensive rats by the modulation of ACE2 and profilin-1 expression. Regul Pept 166, 90-97.
-
(2011)
Regul Pept
, vol.166
, pp. 90-97
-
-
Zhong, J.C.1
Ye, J.Y.2
Jin, H.Y.3
Yu, X.4
Yu, H.M.5
Zhu, D.L.6
Gao, P.J.7
Huang, D.Y.8
Shuster, M.9
Loibner, H.10
Guo, J.M.11
Yu, X.Y.12
Xiao, B.X.13
Gong, Z.H.14
Penninger, J.M.15
Oudit, G.Y.16
-
58
-
-
0037177171
-
New concepts in diastolic dysfunction and diastolic heart failure: Part II: causal mechanisms and treatment
-
Zile MR & Brutsaert DL (2002). New concepts in diastolic dysfunction and diastolic heart failure: Part II: causal mechanisms and treatment. Circulation 105, 1503-1508.
-
(2002)
Circulation
, vol.105
, pp. 1503-1508
-
-
Zile, M.R.1
Brutsaert, D.L.2
|