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Volumn 8, Issue JUL, 2017, Pages

Cytokine-Induced killer cells as pharmacological tools for cancer immunotherapy

Author keywords

Cancer therapy; Clinical trials; Cytokine induced killer cells; Immunotherapy; Pharmacological tools

Indexed keywords

ANTINEOPLASTIC AGENT; BISPECIFIC ANTIBODY; BRENTUXIMAB VEDOTIN; CD3 ANTIBODY; CHIMERIC ANTIGEN RECEPTOR; CISPLATIN; CYTOKINE; DENDRITIC CELL VACCINE; DOCETAXEL; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 7; NANOPARTICLE; OBINUTUZUMAB; RITUXIMAB; TEMOZOLOMIDE; TUMOR NECROSIS FACTOR;

EID: 85022182380     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00774     Document Type: Review
Times cited : (118)

References (147)
  • 1
    • 84864367909 scopus 로고    scopus 로고
    • Global cancer transitions according to the Human Development Index (2008-2030): a population-based study
    • Bray F, Jemal A, Grey N, Ferlay J, Forman D. Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. Lancet Oncol (2012) 13(8):790-801. doi:10.1016/S1470-2045(12)70211-5
    • (2012) Lancet Oncol , vol.13 , Issue.8 , pp. 790-801
    • Bray, F.1    Jemal, A.2    Grey, N.3    Ferlay, J.4    Forman, D.5
  • 2
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer (2010) 127(12):2893-917. doi:10.1002/ijc.25516
    • (2010) Int J Cancer , vol.127 , Issue.12 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4    Mathers, C.5    Parkin, D.M.6
  • 3
    • 0018971129 scopus 로고
    • In vitro growth of murine T cell. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors
    • Yron I, Wood TA Jr, Spiess PJ, Rosenberg SA. In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors. J Immunol (1980) 125(1):238-45.
    • (1980) J Immunol , vol.125 , Issue.1 , pp. 238-245
    • Yron, I.1    Wood, T.A.2    Spiess, P.J.3    Rosenberg, S.A.4
  • 4
    • 0018958267 scopus 로고
    • The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors
    • Lotze MT, Line BR, Mathisen DJ, Rosenberg SA. The in vivo distribution of autologous human and murine lymphoid cells grown in T cell growth factor (TCGF): implications for the adoptive immunotherapy of tumors. J Immunol (1980) 125(4):1487-93.
    • (1980) J Immunol , vol.125 , Issue.4 , pp. 1487-1493
    • Lotze, M.T.1    Line, B.R.2    Mathisen, D.J.3    Rosenberg, S.A.4
  • 5
    • 0025856106 scopus 로고
    • Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
    • Schmidt-Wolf IG, Negrin RS, Kiem HP, Blume KG, Weissman IL. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J Exp Med (1991) 174(1):139-49. doi:10.1084/jem.174.1.139
    • (1991) J Exp Med , vol.174 , Issue.1 , pp. 139-149
    • Schmidt-Wolf, I.G.1    Negrin, R.S.2    Kiem, H.P.3    Blume, K.G.4    Weissman, I.L.5
  • 6
    • 0027860412 scopus 로고
    • Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells
    • Schmidt-Wolf IG, Lefterova P, Mehta BA, Fernandez LP, Huhn D, Blume KG, et al. Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells. Exp Hematol (1993) 21(13):1673-9.
    • (1993) Exp Hematol , vol.21 , Issue.13 , pp. 1673-1679
    • Schmidt-Wolf, I.G.1    Lefterova, P.2    Mehta, B.A.3    Fernandez, L.P.4    Huhn, D.5    Blume, K.G.6
  • 7
    • 0027991676 scopus 로고
    • Cytotoxicity of cytokine-induced killer cells coated with bispecific antibody against acute myeloid leukemia cells
    • Kaneko T, Fusauch Y, Kakui Y, Okumura K, Mizoguchi H, Oshimi K. Cytotoxicity of cytokine-induced killer cells coated with bispecific antibody against acute myeloid leukemia cells. Leuk Lymphoma (1994) 14(3-4):219-29. doi:10.3109/10428199409049672
    • (1994) Leuk Lymphoma , vol.14 , Issue.3-4 , pp. 219-229
    • Kaneko, T.1    Fusauch, Y.2    Kakui, Y.3    Okumura, K.4    Mizoguchi, H.5    Oshimi, K.6
  • 8
    • 0032433319 scopus 로고    scopus 로고
    • Generation of cytokine-induced killer cells using exogenous interleukin-2, -7 or -12
    • Zoll B, Lefterova P, Csipai M, Finke S, Trojaneck B, Ebert O, et al. Generation of cytokine-induced killer cells using exogenous interleukin-2, -7 or -12. Cancer Immunol Immunother (1998) 47(4):221-6. doi:10.1007/s002620050524
    • (1998) Cancer Immunol Immunother , vol.47 , Issue.4 , pp. 221-226
    • Zoll, B.1    Lefterova, P.2    Csipai, M.3    Finke, S.4    Trojaneck, B.5    Ebert, O.6
  • 9
    • 0032698796 scopus 로고    scopus 로고
    • Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma
    • Schmidt-Wolf IG, Finke S, Trojaneck B, Denkena A, Lefterova P, Schwella N, et al. Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma. Br J Cancer (1999) 81(6):1009-16. doi:10.1038/sj.bjc.6690800
    • (1999) Br J Cancer , vol.81 , Issue.6 , pp. 1009-1016
    • Schmidt-Wolf, I.G.1    Finke, S.2    Trojaneck, B.3    Denkena, A.4    Lefterova, P.5    Schwella, N.6
  • 10
    • 0035201489 scopus 로고    scopus 로고
    • Interactions between dendritic cells and cytokine-induced killer cells lead to an activation of both populations
    • Marten A, Ziske C, Schottker B, Renoth S, Weineck S, Buttgereit P, et al. Interactions between dendritic cells and cytokine-induced killer cells lead to an activation of both populations. J Immunother (2001) 24(6):502-10. doi:10.1097/00002371-200111000-00007
    • (2001) J Immunother , vol.24 , Issue.6 , pp. 502-510
    • Marten, A.1    Ziske, C.2    Schottker, B.3    Renoth, S.4    Weineck, S.5    Buttgereit, P.6
  • 11
    • 1842526956 scopus 로고    scopus 로고
    • Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells
    • Verneris MR, Karimi M, Baker J, Jayaswal A, Negrin RS. Role of NKG2D signaling in the cytotoxicity of activated and expanded CD8+ T cells. Blood (2004) 103(8):3065-72. doi:10.1182/blood-2003-06-2125
    • (2004) Blood , vol.103 , Issue.8 , pp. 3065-3072
    • Verneris, M.R.1    Karimi, M.2    Baker, J.3    Jayaswal, A.4    Negrin, R.S.5
  • 12
    • 33745565374 scopus 로고    scopus 로고
    • Treatment of advanced gastric cancer by chemotherapy combined with autologous cytokine-induced killer cells
    • Jiang J, Xu N, Wu C, Deng H, Lu M, Li M, et al. Treatment of advanced gastric cancer by chemotherapy combined with autologous cytokine-induced killer cells. Anticancer Res (2006) 26(3B):2237-42.
    • (2006) Anticancer Res , vol.26 , Issue.3 B , pp. 2237-2242
    • Jiang, J.1    Xu, N.2    Wu, C.3    Deng, H.4    Lu, M.5    Li, M.6
  • 13
    • 78649926094 scopus 로고    scopus 로고
    • Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells
    • Contag CH, Sikorski R, Negrin RS, Schmidt T, Fan AC, Bachireddy P, et al. Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells. Cancer Res (2010) 70(23):9837-45. doi:10.1158/0008-5472.CAN-10-2650
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9837-9845
    • Contag, C.H.1    Sikorski, R.2    Negrin, R.S.3    Schmidt, T.4    Fan, A.C.5    Bachireddy, P.6
  • 14
    • 78751628167 scopus 로고    scopus 로고
    • Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)
    • Hontscha C, Borck Y, Zhou H, Messmer D, Schmidt-Wolf IG. Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC). J Cancer Res Clin Oncol (2011) 137(2):305-10. doi:10.1007/s00432-010-0887-7
    • (2011) J Cancer Res Clin Oncol , vol.137 , Issue.2 , pp. 305-310
    • Hontscha, C.1    Borck, Y.2    Zhou, H.3    Messmer, D.4    Schmidt-Wolf, I.G.5
  • 15
    • 84859701718 scopus 로고    scopus 로고
    • Improved activation toward primary colorectal cancer cells by antigen-specific targeting autologous cytokine-induced killer cells
    • Schlimper C, Hombach AA, Abken H, Schmidt-Wolf IG. Improved activation toward primary colorectal cancer cells by antigen-specific targeting autologous cytokine-induced killer cells. Clin Dev Immunol (2012) 2012:238924. doi:10.1155/2012/238924
    • (2012) Clin Dev Immunol , vol.2012 , pp. 238924
    • Schlimper, C.1    Hombach, A.A.2    Abken, H.3    Schmidt-Wolf, I.G.4
  • 16
    • 84961603856 scopus 로고    scopus 로고
    • Implication of combined PD-L1/PD-1 blockade with cytokine-induced killer cells as a synergistic immunotherapy for gastrointestinal cancer
    • Dai C, Lin F, Geng R, Ge X, Tang W, Chang J, et al. Implication of combined PD-L1/PD-1 blockade with cytokine-induced killer cells as a synergistic immunotherapy for gastrointestinal cancer. Oncotarget (2016) 7(9):10332-44. doi:10.18632/oncotarget.7243
    • (2016) Oncotarget , vol.7 , Issue.9 , pp. 10332-10344
    • Dai, C.1    Lin, F.2    Geng, R.3    Ge, X.4    Tang, W.5    Chang, J.6
  • 17
    • 84977156500 scopus 로고    scopus 로고
    • Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling
    • Lee HK, Kim YG, Kim JS, Park EJ, Kim B, Park KH, et al. Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling. Cancer Lett (2016) 378(2):142-9. doi:10.1016/j.canlet.2016.05.020
    • (2016) Cancer Lett , vol.378 , Issue.2 , pp. 142-149
    • Lee, H.K.1    Kim, Y.G.2    Kim, J.S.3    Park, E.J.4    Kim, B.5    Park, K.H.6
  • 18
    • 0036162007 scopus 로고    scopus 로고
    • Generation of cytokine-induced killer cells from leukaemic samples with in vitro cytotoxicity against autologous and allogeneic leukaemic blasts
    • Linn YC, Lau LC, Hui KM. Generation of cytokine-induced killer cells from leukaemic samples with in vitro cytotoxicity against autologous and allogeneic leukaemic blasts. Br J Haematol (2002) 116(1):78-86. doi:10.1046/j.1365-2141.2002.03247.x
    • (2002) Br J Haematol , vol.116 , Issue.1 , pp. 78-86
    • Linn, Y.C.1    Lau, L.C.2    Hui, K.M.3
  • 19
    • 84901434103 scopus 로고    scopus 로고
    • A killer choice for cancer immunotherapy
    • Schmidt TL, Negrin RS, Contag CH. A killer choice for cancer immunotherapy. Immunol Res (2014) 58(2-3):300-6. doi:10.1007/s12026-014-8507-2
    • (2014) Immunol Res , vol.58 , Issue.2-3 , pp. 300-306
    • Schmidt, T.L.1    Negrin, R.S.2    Contag, C.H.3
  • 20
    • 78751489103 scopus 로고    scopus 로고
    • Enhanced killing of human B-cell lymphoma targets by combined use of cytokine-induced killer cell (CIK) cultures and anti-CD20 antibodies
    • Pievani A, Belussi C, Klein C, Rambaldi A, Golay J, Introna M. Enhanced killing of human B-cell lymphoma targets by combined use of cytokine-induced killer cell (CIK) cultures and anti-CD20 antibodies. Blood (2011) 117(2):510-8. doi:10.1182/blood-2010-06-290858
    • (2011) Blood , vol.117 , Issue.2 , pp. 510-518
    • Pievani, A.1    Belussi, C.2    Klein, C.3    Rambaldi, A.4    Golay, J.5    Introna, M.6
  • 21
    • 19444383219 scopus 로고    scopus 로고
    • Comparative gene expression profiling of cytokine-induced killer cells in response to acute myloid leukemic and acute lymphoblastic leukemic stimulators using oligonucleotide arrays
    • Linn YC, Wang SM, Hui KM. Comparative gene expression profiling of cytokine-induced killer cells in response to acute myloid leukemic and acute lymphoblastic leukemic stimulators using oligonucleotide arrays. Exp Hematol (2005) 33(6):671-81. doi:10.1016/j.exphem.2005.03.005
    • (2005) Exp Hematol , vol.33 , Issue.6 , pp. 671-681
    • Linn, Y.C.1    Wang, S.M.2    Hui, K.M.3
  • 22
    • 84855520803 scopus 로고    scopus 로고
    • Cytokine induced killer cells as promising immunotherapy for solid tumors
    • Sangiolo D. Cytokine induced killer cells as promising immunotherapy for solid tumors. J Cancer (2011) 2:363-8. doi:10.7150/jca.2.363
    • (2011) J Cancer , vol.2 , pp. 363-368
    • Sangiolo, D.1
  • 23
    • 0028103808 scopus 로고
    • A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency
    • Lu PH, Negrin RS. A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. J Immunol (1994) 153(4):1687-96.
    • (1994) J Immunol , vol.153 , Issue.4 , pp. 1687-1696
    • Lu, P.H.1    Negrin, R.S.2
  • 24
    • 33750151607 scopus 로고    scopus 로고
    • Rapid and massive expansion of cord blood-derived cytokine-induced killer cells: an innovative proposal for the treatment of leukemia relapse after cord blood transplantation
    • Introna M, Franceschetti M, Ciocca A, Borleri G, Conti E, Golay J, et al. Rapid and massive expansion of cord blood-derived cytokine-induced killer cells: an innovative proposal for the treatment of leukemia relapse after cord blood transplantation. Bone Marrow Transplant (2006) 38(9):621-7. doi:10.1038/sj.bmt.1705503
    • (2006) Bone Marrow Transplant , vol.38 , Issue.9 , pp. 621-627
    • Introna, M.1    Franceschetti, M.2    Ciocca, A.3    Borleri, G.4    Conti, E.5    Golay, J.6
  • 25
    • 84865480017 scopus 로고    scopus 로고
    • Ex vivo allogeneic stimulation significantly improves expansion of cytokine-induced killer cells without increasing their alloreactivity across HLA barriers
    • Todorovic M, Mesiano G, Gammaitoni L, Leuci V, Giraudo Diego L, Cammarata C, et al. Ex vivo allogeneic stimulation significantly improves expansion of cytokine-induced killer cells without increasing their alloreactivity across HLA barriers. J Immunother (2012) 35(7):579-86. doi:10.1097/CJI.0b013e31826b1fd9
    • (2012) J Immunother , vol.35 , Issue.7 , pp. 579-586
    • Todorovic, M.1    Mesiano, G.2    Gammaitoni, L.3    Leuci, V.4    Giraudo Diego, L.5    Cammarata, C.6
  • 26
    • 0029040855 scopus 로고
    • Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes
    • Hayes MP, Wang J, Norcross MA. Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. Blood (1995) 86(2):646-50.
    • (1995) Blood , vol.86 , Issue.2 , pp. 646-650
    • Hayes, M.P.1    Wang, J.2    Norcross, M.A.3
  • 27
    • 0030064148 scopus 로고    scopus 로고
    • The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells
    • Ma X, Chow JM, Gri G, Carra G, Gerosa F, Wolf SF, et al. The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells. J Exp Med (1996) 183(1):147-57. doi:10.1084/jem.183.1.147
    • (1996) J Exp Med , vol.183 , Issue.1 , pp. 147-157
    • Ma, X.1    Chow, J.M.2    Gri, G.3    Carra, G.4    Gerosa, F.5    Wolf, S.F.6
  • 28
    • 0034948138 scopus 로고    scopus 로고
    • CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells
    • Lopez RD, Waller EK, Lu PH, Negrin RS. CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells. Cancer Immunol Immunother (2001) 49(12):629-40. doi:10.1007/s002620000148
    • (2001) Cancer Immunol Immunother , vol.49 , Issue.12 , pp. 629-640
    • Lopez, R.D.1    Waller, E.K.2    Lu, P.H.3    Negrin, R.S.4
  • 29
    • 0023126984 scopus 로고
    • Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta
    • Ochoa AC, Gromo G, Alter BJ, Sondel PM, Bach FH. Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta. J Immunol (1987) 138(8):2728-33.
    • (1987) J Immunol , vol.138 , Issue.8 , pp. 2728-2733
    • Ochoa, A.C.1    Gromo, G.2    Alter, B.J.3    Sondel, P.M.4    Bach, F.H.5
  • 30
    • 0023721718 scopus 로고
    • Augmentation of cell number and LAK activity in peripheral blood mononuclear cells activated with anti-CD3 and interleukin-2. Preliminary results in children with acute lymphocytic leukemia and neuroblastoma
    • Anderson PM, Bach FH, Ochoa AC. Augmentation of cell number and LAK activity in peripheral blood mononuclear cells activated with anti-CD3 and interleukin-2. Preliminary results in children with acute lymphocytic leukemia and neuroblastoma. Cancer Immunol Immunother (1988) 27(1):82-8. doi:10.1007/BF00205763
    • (1988) Cancer Immunol Immunother , vol.27 , Issue.1 , pp. 82-88
    • Anderson, P.M.1    Bach, F.H.2    Ochoa, A.C.3
  • 31
    • 14244263846 scopus 로고    scopus 로고
    • A phase I trial of autologous cytokine-induced killer cells for the treatment of relapsed Hodgkin disease and non-Hodgkin lymphoma
    • Leemhuis T, Wells S, Scheffold C, Edinger M, Negrin RS. A phase I trial of autologous cytokine-induced killer cells for the treatment of relapsed Hodgkin disease and non-Hodgkin lymphoma. Biol Blood Marrow Transplant (2005) 11(3):181-7. doi:10.1016/j.bbmt.2004.11.019
    • (2005) Biol Blood Marrow Transplant , vol.11 , Issue.3 , pp. 181-187
    • Leemhuis, T.1    Wells, S.2    Scheffold, C.3    Edinger, M.4    Negrin, R.S.5
  • 32
    • 0035874525 scopus 로고    scopus 로고
    • Expansion of cytolytic CD8(+) natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon gamma production
    • Baker J, Verneris MR, Ito M, Shizuru JA, Negrin RS. Expansion of cytolytic CD8(+) natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon gamma production. Blood (2001) 97(10):2923-31. doi:10.1182/blood.V97.10.2923
    • (2001) Blood , vol.97 , Issue.10 , pp. 2923-2931
    • Baker, J.1    Verneris, M.R.2    Ito, M.3    Shizuru, J.A.4    Negrin, R.S.5
  • 33
    • 84860713073 scopus 로고    scopus 로고
    • Review of Chinese clinical trials on CIK cell treatment for malignancies
    • Li XD, Xu B, Wu J, Ji M, Xu BH, Jiang JT, et al. Review of Chinese clinical trials on CIK cell treatment for malignancies. Clin Transl Oncol (2012) 14(2):102-8. doi:10.1007/s12094-012-0768-4
    • (2012) Clin Transl Oncol , vol.14 , Issue.2 , pp. 102-108
    • Li, X.D.1    Xu, B.2    Wu, J.3    Ji, M.4    Xu, B.H.5    Jiang, J.T.6
  • 35
    • 78649732786 scopus 로고    scopus 로고
    • Thymoglobulin, interferon-gamma and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures
    • Bonanno G, Iudicone P, Mariotti A, Procoli A, Pandolfi A, Fioravanti D, et al. Thymoglobulin, interferon-gamma and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures. J Transl Med (2010) 8:129. doi:10.1186/1479-5876-8-129
    • (2010) J Transl Med , vol.8 , pp. 129
    • Bonanno, G.1    Iudicone, P.2    Mariotti, A.3    Procoli, A.4    Pandolfi, A.5    Fioravanti, D.6
  • 36
    • 83755188591 scopus 로고    scopus 로고
    • The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells
    • Rettinger E, Kuci S, Naumann I, Becker P, Kreyenberg H, Anzaghe M, et al. The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells. Cytotherapy (2012) 14(1):91-103. doi:10.3109/14653249.2011.613931
    • (2012) Cytotherapy , vol.14 , Issue.1 , pp. 91-103
    • Rettinger, E.1    Kuci, S.2    Naumann, I.3    Becker, P.4    Kreyenberg, H.5    Anzaghe, M.6
  • 37
    • 85016166516 scopus 로고    scopus 로고
    • Dual functional capability of dendritic cells - cytokine-induced killer cells in improving side effects of colorectal cancer therapy
    • Mosinska P, Gabryelska A, Zasada M, Fichna J. Dual functional capability of dendritic cells - cytokine-induced killer cells in improving side effects of colorectal cancer therapy. Front Pharmacol (2017) 8:126. doi:10.3389/fphar.2017.00126
    • (2017) Front Pharmacol , vol.8 , pp. 126
    • Mosinska, P.1    Gabryelska, A.2    Zasada, M.3    Fichna, J.4
  • 38
    • 80053210017 scopus 로고    scopus 로고
    • Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation
    • Laport GG, Sheehan K, Baker J, Armstrong R, Wong RM, Lowsky R, et al. Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant (2011) 17(11):1679-87. doi:10.1016/j.bbmt.2011.05.012
    • (2011) Biol Blood Marrow Transplant , vol.17 , Issue.11 , pp. 1679-1687
    • Laport, G.G.1    Sheehan, K.2    Baker, J.3    Armstrong, R.4    Wong, R.M.5    Lowsky, R.6
  • 39
    • 84863722188 scopus 로고    scopus 로고
    • The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies
    • Linn YC, Niam M, Chu S, Choong A, Yong HX, Heng KK, et al. The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies. Bone Marrow Transplant (2012) 47(7):957-66. doi:10.1038/bmt.2011.202
    • (2012) Bone Marrow Transplant , vol.47 , Issue.7 , pp. 957-966
    • Linn, Y.C.1    Niam, M.2    Chu, S.3    Choong, A.4    Yong, H.X.5    Heng, K.K.6
  • 40
    • 34548801834 scopus 로고    scopus 로고
    • Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study
    • Introna M, Borleri G, Conti E, Franceschetti M, Barbui AM, Broady R, et al. Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study. Haematologica (2007) 92(7):952-9. doi:10.3324/haematol.11132
    • (2007) Haematologica , vol.92 , Issue.7 , pp. 952-959
    • Introna, M.1    Borleri, G.2    Conti, E.3    Franceschetti, M.4    Barbui, A.M.5    Broady, R.6
  • 41
    • 77958581448 scopus 로고    scopus 로고
    • Optimized protocols for generation of cord blood-derived cytokine-induced killer/natural killer cells
    • Li Y, Schmidt-Wolf IG, Wu YF, Huang SL, Wei J, Fang J, et al. Optimized protocols for generation of cord blood-derived cytokine-induced killer/natural killer cells. Anticancer Res (2010) 30(9):3493-9.
    • (2010) Anticancer Res , vol.30 , Issue.9 , pp. 3493-3499
    • Li, Y.1    Schmidt-Wolf, I.G.2    Wu, Y.F.3    Huang, S.L.4    Wei, J.5    Fang, J.6
  • 42
    • 84927125715 scopus 로고    scopus 로고
    • Phenotypic characterization and anti-tumor effects of cytokine-induced killer cells derived from cord blood
    • Zhang Z, Zhao X, Zhang T, Wang L, Yang L, Huang L, et al. Phenotypic characterization and anti-tumor effects of cytokine-induced killer cells derived from cord blood. Cytotherapy (2015) 17(1):86-97. doi:10.1016/j.jcyt.2014.09.006
    • (2015) Cytotherapy , vol.17 , Issue.1 , pp. 86-97
    • Zhang, Z.1    Zhao, X.2    Zhang, T.3    Wang, L.4    Yang, L.5    Huang, L.6
  • 43
    • 84937637214 scopus 로고    scopus 로고
    • Efficacy and safety of cord blood-derived cytokine-induced killer cells in treatment of patients with malignancies
    • Zhang Z, Wang L, Luo Z, Zhao X, Huang J, Li H, et al. Efficacy and safety of cord blood-derived cytokine-induced killer cells in treatment of patients with malignancies. Cytotherapy (2015) 17(8):1130-8. doi:10.1016/j.jcyt.2015.04.002
    • (2015) Cytotherapy , vol.17 , Issue.8 , pp. 1130-1138
    • Zhang, Z.1    Wang, L.2    Luo, Z.3    Zhao, X.4    Huang, J.5    Li, H.6
  • 44
    • 79952734945 scopus 로고    scopus 로고
    • Cord blood-derived cytokine-induced killer cells biotherapy combined with second-line chemotherapy in the treatment of advanced solid malignancies
    • Niu Q, Wang W, Li Y, Qin S, Wang Y, Wan G, et al. Cord blood-derived cytokine-induced killer cells biotherapy combined with second-line chemotherapy in the treatment of advanced solid malignancies. Int Immunopharmacol (2011) 11(4):449-56. doi:10.1016/j.intimp.2010.12.014
    • (2011) Int Immunopharmacol , vol.11 , Issue.4 , pp. 449-456
    • Niu, Q.1    Wang, W.2    Li, Y.3    Qin, S.4    Wang, Y.5    Wan, G.6
  • 45
    • 84859570163 scopus 로고    scopus 로고
    • New adoptive immunotherapy strategies for solid tumours with CIK cells
    • Thanendrarajan S, Kim Y, Schmidt-Wolf I. New adoptive immunotherapy strategies for solid tumours with CIK cells. Expert Opin Biol Ther (2012) 12(5):565-72. doi:10.1517/14712598.2012.668879
    • (2012) Expert Opin Biol Ther , vol.12 , Issue.5 , pp. 565-572
    • Thanendrarajan, S.1    Kim, Y.2    Schmidt-Wolf, I.3
  • 46
    • 84902157972 scopus 로고    scopus 로고
    • An update on new adoptive immunotherapy strategies for solid tumors with cytokine-induced killer cells
    • Jakel CE, Schmidt-Wolf IG. An update on new adoptive immunotherapy strategies for solid tumors with cytokine-induced killer cells. Expert Opin Biol Ther (2014) 14(7):905-16. doi:10.1517/14712598.2014.900537
    • (2014) Expert Opin Biol Ther , vol.14 , Issue.7 , pp. 905-916
    • Jakel, C.E.1    Schmidt-Wolf, I.G.2
  • 47
    • 84859882648 scopus 로고    scopus 로고
    • Interleukin-6 inhibits regulatory T cells and improves the proliferation and cytotoxic activity of cytokine-induced killer cells
    • Lin G, Wang J, Lao X, Li L, Li S, Zhang J, et al. Interleukin-6 inhibits regulatory T cells and improves the proliferation and cytotoxic activity of cytokine-induced killer cells. J Immunother (2012) 35(4):337-43. doi:10.1097/CJI.0b013e318255ada3
    • (2012) J Immunother , vol.35 , Issue.4 , pp. 337-343
    • Lin, G.1    Wang, J.2    Lao, X.3    Li, L.4    Li, S.5    Zhang, J.6
  • 49
    • 0033798003 scopus 로고    scopus 로고
    • Modulation of cell surface markers on NK-like T lymphocytes by using IL-2, IL-7 or IL-12 in vitro stimulation
    • Zoll B, Lefterova P, Ebert O, Huhn D, Von Ruecker A, Schmidt-Wolf IG. Modulation of cell surface markers on NK-like T lymphocytes by using IL-2, IL-7 or IL-12 in vitro stimulation. Cytokine (2000) 12(9):1385-90. doi:10.1006/cyto.2000.0733
    • (2000) Cytokine , vol.12 , Issue.9 , pp. 1385-1390
    • Zoll, B.1    Lefterova, P.2    Ebert, O.3    Huhn, D.4    Von Ruecker, A.5    Schmidt-Wolf, I.G.6
  • 50
    • 84866508693 scopus 로고    scopus 로고
    • Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model
    • Yang Z, Zhang Q, Xu K, Shan J, Shen J, Liu L, et al. Combined therapy with cytokine-induced killer cells and oncolytic adenovirus expressing IL-12 induce enhanced antitumor activity in liver tumor model. PLoS One (2012) 7(9):e44802. doi:10.1371/journal.pone.0044802
    • (2012) PLoS One , vol.7 , Issue.9
    • Yang, Z.1    Zhang, Q.2    Xu, K.3    Shan, J.4    Shen, J.5    Liu, L.6
  • 51
    • 84887123089 scopus 로고    scopus 로고
    • 6+ cells and downregulating regulatory T cells as well as IL-35
    • 6+ cells and downregulating regulatory T cells as well as IL-35. J Immunother (2013) 36(9):462-7. doi:10.1097/CJI.0000000000000001
    • (2013) J Immunother , vol.36 , Issue.9 , pp. 462-467
    • Tao, Q.1    Chen, T.2    Tao, L.3    Wang, H.4    Pan, Y.5    Xiong, S.6
  • 52
    • 84898884888 scopus 로고    scopus 로고
    • The CIK cells stimulated with combination of IL-2 and IL-15 provide an improved cytotoxic capacity against human lung adenocarcinoma
    • Wei C, Wang W, Pang W, Meng M, Jiang L, Xue S, et al. The CIK cells stimulated with combination of IL-2 and IL-15 provide an improved cytotoxic capacity against human lung adenocarcinoma. Tumour Biol (2014) 35(3):1997-2007. doi:10.1007/s13277-013-1265-2
    • (2014) Tumour Biol , vol.35 , Issue.3 , pp. 1997-2007
    • Wei, C.1    Wang, W.2    Pang, W.3    Meng, M.4    Jiang, L.5    Xue, S.6
  • 53
    • 84954390613 scopus 로고    scopus 로고
    • Interleukin-15-transferred cytokine-induced killer cells elevated anti-tumor activity in a gastric tumor-bearing nude mice model
    • Peng Z, Liang W, Li Z, Xu Y, Chen L. Interleukin-15-transferred cytokine-induced killer cells elevated anti-tumor activity in a gastric tumor-bearing nude mice model. Cell Biol Int (2016) 40(2):204-13. doi:10.1002/cbin.10553
    • (2016) Cell Biol Int , vol.40 , Issue.2 , pp. 204-213
    • Peng, Z.1    Liang, W.2    Li, Z.3    Xu, Y.4    Chen, L.5
  • 54
    • 84978870825 scopus 로고    scopus 로고
    • Cytotoxic potential of IL-15-activated cytokine-induced killer cells against human neuroblastoma cells
    • Cappel C, Huenecke S, Suemmerer A, Erben S, Rettinger E, Pfirrmann V, et al. Cytotoxic potential of IL-15-activated cytokine-induced killer cells against human neuroblastoma cells. Pediatr Blood Cancer (2016) 63(12):2230-9. doi:10.1002/pbc.26147
    • (2016) Pediatr Blood Cancer , vol.63 , Issue.12 , pp. 2230-2239
    • Cappel, C.1    Huenecke, S.2    Suemmerer, A.3    Erben, S.4    Rettinger, E.5    Pfirrmann, V.6
  • 55
    • 85006274856 scopus 로고    scopus 로고
    • Interleukin-15 enhances cytokine induced killer (CIK) cytotoxic potential against epithelial cancer cell lines via an innate pathway
    • Iudicone P, Fioravanti D, Cicchetti E, Zizzari IG, Pandolfi A, Scocchera R, et al. Interleukin-15 enhances cytokine induced killer (CIK) cytotoxic potential against epithelial cancer cell lines via an innate pathway. Hum Immunol (2016) 77(12):1239-47. doi:10.1016/j.humimm.2016.09.003
    • (2016) Hum Immunol , vol.77 , Issue.12 , pp. 1239-1247
    • Iudicone, P.1    Fioravanti, D.2    Cicchetti, E.3    Zizzari, I.G.4    Pandolfi, A.5    Scocchera, R.6
  • 56
    • 84890528855 scopus 로고    scopus 로고
    • Toll-like receptor 4 is required for the cytotoxicity of cytokine-induced killer cells
    • Cai C, Chen W, Miao D, Cheng L, Yang G, Zhang L, et al. Toll-like receptor 4 is required for the cytotoxicity of cytokine-induced killer cells. Acta Haematol (2014) 132(1):5-9. doi:10.1159/000355190
    • (2014) Acta Haematol , vol.132 , Issue.1 , pp. 5-9
    • Cai, C.1    Chen, W.2    Miao, D.3    Cheng, L.4    Yang, G.5    Zhang, L.6
  • 57
    • 84908058418 scopus 로고    scopus 로고
    • Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor
    • Wang W, Meng M, Zhang Y, Wei C, Xie Y, Jiang L, et al. Global transcriptome-wide analysis of CIK cells identify distinct roles of IL-2 and IL-15 in acquisition of cytotoxic capacity against tumor. BMC Med Genomics (2014) 7:49. doi:10.1186/1755-8794-7-49
    • (2014) BMC Med Genomics , vol.7 , pp. 49
    • Wang, W.1    Meng, M.2    Zhang, Y.3    Wei, C.4    Xie, Y.5    Jiang, L.6
  • 58
    • 84890525812 scopus 로고    scopus 로고
    • Multiple cytotoxic factors involved in IL-21 enhanced antitumor function of CIK cells signaled through STAT-3 and STAT5b pathways
    • Rajbhandary S, Zhao MF, Zhao N, Lu WY, Zhu HB, Xiao X, et al. Multiple cytotoxic factors involved in IL-21 enhanced antitumor function of CIK cells signaled through STAT-3 and STAT5b pathways. Asian Pac J Cancer Prev (2013) 14(10):5825-31. doi:10.7314/APJCP.2013.14.10.5825
    • (2013) Asian Pac J Cancer Prev , vol.14 , Issue.10 , pp. 5825-5831
    • Rajbhandary, S.1    Zhao, M.F.2    Zhao, N.3    Lu, W.Y.4    Zhu, H.B.5    Xiao, X.6
  • 59
    • 84874307674 scopus 로고    scopus 로고
    • Effects and mechanism on anti-leukemic activity of cytokine-induced killer cells with an endogenous expression of interleukin-21
    • Zhao N, Zhao MF, Rajbhandary S, Lu WY, Zhu HB, Ma L, et al. Effects and mechanism on anti-leukemic activity of cytokine-induced killer cells with an endogenous expression of interleukin-21. Zhonghua Yi Xue Za Zhi (2013) 93(4):293-9. doi:10.3760/cma.j.issn.0376-2491.2013.04.013
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , Issue.4 , pp. 293-299
    • Zhao, N.1    Zhao, M.F.2    Rajbhandary, S.3    Lu, W.Y.4    Zhu, H.B.5    Ma, L.6
  • 60
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature (1998) 392(6673):245-52. doi:10.1038/32588
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 61
    • 84939183238 scopus 로고    scopus 로고
    • Dendritic cells as pharmacological tools for cancer immunotherapy
    • Anguille S, Smits EL, Bryant C, Van Acker HH, Goossens H, Lion E, et al. Dendritic cells as pharmacological tools for cancer immunotherapy. Pharmacol Rev (2015) 67(4):731-53. doi:10.1124/pr.114.009456
    • (2015) Pharmacol Rev , vol.67 , Issue.4 , pp. 731-753
    • Anguille, S.1    Smits, E.L.2    Bryant, C.3    Van Acker, H.H.4    Goossens, H.5    Lion, E.6
  • 62
    • 0032903599 scopus 로고    scopus 로고
    • Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo
    • Fernandez NC, Lozier A, Flament C, Ricciardi-Castagnoli P, Bellet D, Suter M, et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat Med (1999) 5(4):405-11. doi:10.1038/7403
    • (1999) Nat Med , vol.5 , Issue.4 , pp. 405-411
    • Fernandez, N.C.1    Lozier, A.2    Flament, C.3    Ricciardi-Castagnoli, P.4    Bellet, D.5    Suter, M.6
  • 63
    • 0034133499 scopus 로고    scopus 로고
    • Human invariant valpha24+ natural killer T cells activated by alpha-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms distinct from T cells and natural killer cells
    • Nicol A, Nieda M, Koezuka Y, Porcelli S, Suzuki K, Tadokoro K, et al. Human invariant valpha24+ natural killer T cells activated by alpha-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms distinct from T cells and natural killer cells. Immunology (2000) 99(2):229-34. doi:10.1046/j.1365-2567.2000.00952.x
    • (2000) Immunology , vol.99 , Issue.2 , pp. 229-234
    • Nicol, A.1    Nieda, M.2    Koezuka, Y.3    Porcelli, S.4    Suzuki, K.5    Tadokoro, K.6
  • 64
    • 84979663267 scopus 로고    scopus 로고
    • Influence of autologous dendritic cells on cytokine-induced killer cell proliferation, cell phenotype and antitumor activity in vitro
    • Cao J, Chen C, Wang Y, Chen X, Chen Z, Luo X. Influence of autologous dendritic cells on cytokine-induced killer cell proliferation, cell phenotype and antitumor activity in vitro. Oncol Lett (2016) 12(3):2033-7. doi:10.3892/ol.2016.4839
    • (2016) Oncol Lett , vol.12 , Issue.3 , pp. 2033-2037
    • Cao, J.1    Chen, C.2    Wang, Y.3    Chen, X.4    Chen, Z.5    Luo, X.6
  • 65
    • 84899413645 scopus 로고    scopus 로고
    • Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells
    • Pan Y, Tao Q, Wang H, Xiong S, Zhang R, Chen T, et al. Dendritic cells decreased the concomitant expanded Tregs and Tregs related IL-35 in cytokine-induced killer cells and increased their cytotoxicity against leukemia cells. PLoS One (2014) 9(4):e93591. doi:10.1371/journal.pone.0093591
    • (2014) PLoS One , vol.9 , Issue.4
    • Pan, Y.1    Tao, Q.2    Wang, H.3    Xiong, S.4    Zhang, R.5    Chen, T.6
  • 66
    • 84879479216 scopus 로고    scopus 로고
    • Immune response, clinical outcome and safety of dendritic cell vaccine in combination with cytokine-induced killer cell therapy in cancer patients
    • Cui Y, Yang X, Zhu W, Li J, Wu X, Pang Y. Immune response, clinical outcome and safety of dendritic cell vaccine in combination with cytokine-induced killer cell therapy in cancer patients. Oncol Lett (2013) 6(2):537-41. doi:10.3892/ol.2013.1376
    • (2013) Oncol Lett , vol.6 , Issue.2 , pp. 537-541
    • Cui, Y.1    Yang, X.2    Zhu, W.3    Li, J.4    Wu, X.5    Pang, Y.6
  • 67
    • 84923142064 scopus 로고    scopus 로고
    • Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response
    • Shan CC, Shi LR, Ding MQ, Zhu YB, Li XD, Xu B, et al. Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response. Oncol Lett (2015) 9(4):1549-56. doi:10.3892/ol.2015.2977
    • (2015) Oncol Lett , vol.9 , Issue.4 , pp. 1549-1556
    • Shan, C.C.1    Shi, L.R.2    Ding, M.Q.3    Zhu, Y.B.4    Li, X.D.5    Xu, B.6
  • 68
    • 84876232313 scopus 로고    scopus 로고
    • Cytokine-induced killer cells co-cultured with complete tumor antigen-loaded dendritic cells, have enhanced selective cytotoxicity on carboplatin-resistant retinoblastoma cells
    • Wang YF, Kunda PE, Lin JW, Wang H, Chen XM, Liu QL, et al. Cytokine-induced killer cells co-cultured with complete tumor antigen-loaded dendritic cells, have enhanced selective cytotoxicity on carboplatin-resistant retinoblastoma cells. Oncol Rep (2013) 29(5):1841-50. doi:10.3892/or.2013.2315
    • (2013) Oncol Rep , vol.29 , Issue.5 , pp. 1841-1850
    • Wang, Y.F.1    Kunda, P.E.2    Lin, J.W.3    Wang, H.4    Chen, X.M.5    Liu, Q.L.6
  • 69
    • 84995755299 scopus 로고    scopus 로고
    • Dendritic cell-activated cytokine-induced killer cell-mediated immunotherapy is safe and effective for cancer patients >65 years old
    • Liu Y, Liu H, He P, Li J, Liu X, Chen L, et al. Dendritic cell-activated cytokine-induced killer cell-mediated immunotherapy is safe and effective for cancer patients >65 years old. Oncol Lett (2016) 12(6):5205-10. doi:10.3892/ol.2016.5337
    • (2016) Oncol Lett , vol.12 , Issue.6 , pp. 5205-5210
    • Liu, Y.1    Liu, H.2    He, P.3    Li, J.4    Liu, X.5    Chen, L.6
  • 70
    • 84978524657 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy combined with cytokine-induced killer cells effectively suppresses established hepatocellular carcinomas in mice
    • Jung NC, Lee JH, Choi HJ, Hwang SU, Song JY, Seo HG, et al. Dendritic cell immunotherapy combined with cytokine-induced killer cells effectively suppresses established hepatocellular carcinomas in mice. Immunol Invest (2016) 45(6):553-65. doi:10.1080/08820139.2016.1183025
    • (2016) Immunol Invest , vol.45 , Issue.6 , pp. 553-565
    • Jung, N.C.1    Lee, J.H.2    Choi, H.J.3    Hwang, S.U.4    Song, J.Y.5    Seo, H.G.6
  • 71
    • 85011579991 scopus 로고    scopus 로고
    • 2003-2013, a valuable study: autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in stage IV breast cancer
    • Lin M, Liang S, Jiang F, Xu J, Zhu W, Qian W, et al. 2003-2013, a valuable study: autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in stage IV breast cancer. Immunol Lett (2017) 183:37-43. doi:10.1016/j.imlet.2017.01.014
    • (2017) Immunol Lett , vol.183 , pp. 37-43
    • Lin, M.1    Liang, S.2    Jiang, F.3    Xu, J.4    Zhu, W.5    Qian, W.6
  • 72
    • 84880706152 scopus 로고    scopus 로고
    • Oncology meets immunology: the cancer-immunity cycle
    • Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity (2013) 39(1):1-10. doi:10.1016/j.immuni.2013.07.012
    • (2013) Immunity , vol.39 , Issue.1 , pp. 1-10
    • Chen, D.S.1    Mellman, I.2
  • 73
    • 84941025149 scopus 로고    scopus 로고
    • Prospects of immune checkpoint modulators in the treatment of glioblastoma
    • Preusser M, Lim M, Hafler DA, Reardon DA, Sampson JH. Prospects of immune checkpoint modulators in the treatment of glioblastoma. Nat Rev Neurol (2015) 11(9):504-14. doi:10.1038/nrneurol.2015.139
    • (2015) Nat Rev Neurol , vol.11 , Issue.9 , pp. 504-514
    • Preusser, M.1    Lim, M.2    Hafler, D.A.3    Reardon, D.A.4    Sampson, J.H.5
  • 74
    • 65349156913 scopus 로고    scopus 로고
    • Costimulatory and coinhibitory receptors in anti-tumor immunity
    • Driessens G, Kline J, Gajewski TF. Costimulatory and coinhibitory receptors in anti-tumor immunity. Immunol Rev (2009) 229(1):126-44. doi:10.1111/j.1600-065X.2009.00771.x
    • (2009) Immunol Rev , vol.229 , Issue.1 , pp. 126-144
    • Driessens, G.1    Kline, J.2    Gajewski, T.F.3
  • 75
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer (2012) 12(4):252-64. doi:10.1038/nrc3239
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 76
    • 84926160709 scopus 로고    scopus 로고
    • Immune evasion in cancer: mechanistic basis and therapeutic strategies
    • Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, et al. Immune evasion in cancer: mechanistic basis and therapeutic strategies. Semin Cancer Biol (2015) 35(Suppl):S185-98. doi:10.1016/j.semcancer.2015.03.004
    • (2015) Semin Cancer Biol , vol.35 , pp. S185-S198
    • Vinay, D.S.1    Ryan, E.P.2    Pawelec, G.3    Talib, W.H.4    Stagg, J.5    Elkord, E.6
  • 77
    • 84960327660 scopus 로고    scopus 로고
    • Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts
    • Poh SL, Linn YC. Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts. Cancer Immunol Immunother (2016) 65(5):525-36. doi:10.1007/s00262-016-1815-8
    • (2016) Cancer Immunol Immunother , vol.65 , Issue.5 , pp. 525-536
    • Poh, S.L.1    Linn, Y.C.2
  • 78
    • 84873053339 scopus 로고    scopus 로고
    • Antibody-drug conjugates in cancer therapy
    • Sievers EL, Senter PD. Antibody-drug conjugates in cancer therapy. Annu Rev Med (2013) 64:15-29. doi:10.1146/annurev-med-050311-201823
    • (2013) Annu Rev Med , vol.64 , pp. 15-29
    • Sievers, E.L.1    Senter, P.D.2
  • 79
    • 84858785688 scopus 로고    scopus 로고
    • Antibody therapy of cancer
    • Scott AM, Wolchok JD, Old LJ. Antibody therapy of cancer. Nat Rev Cancer (2012) 12(4):278-87. doi:10.1038/nrc3236
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 278-287
    • Scott, A.M.1    Wolchok, J.D.2    Old, L.J.3
  • 80
    • 84922981775 scopus 로고    scopus 로고
    • Anti-CD20 antibody induces the improvement of cytokine-induced killer cell activity via the STAT and MAPK/ERK signaling pathways
    • Deng QI, Bai X, Lv HR, Xiao X, Zhao MF, Li YM. Anti-CD20 antibody induces the improvement of cytokine-induced killer cell activity via the STAT and MAPK/ERK signaling pathways. Exp Ther Med (2015) 9(4):1215-22. doi:10.3892/etm.2015.2264
    • (2015) Exp Ther Med , vol.9 , Issue.4 , pp. 1215-1222
    • Deng, Q.I.1    Bai, X.2    Lv, H.R.3    Xiao, X.4    Zhao, M.F.5    Li, Y.M.6
  • 81
    • 84977515199 scopus 로고    scopus 로고
    • Increased efficacy of brentuximab vedotin (SGN-35) in combination with cytokine-induced killer cells in lymphoma
    • Esser L, Weiher H, Schmidt-Wolf I. Increased efficacy of brentuximab vedotin (SGN-35) in combination with cytokine-induced killer cells in lymphoma. Int J Mol Sci (2016) 17(7):E1056. doi:10.3390/ijms17071056
    • (2016) Int J Mol Sci , vol.17 , Issue.7
    • Esser, L.1    Weiher, H.2    Schmidt-Wolf, I.3
  • 82
    • 84950989868 scopus 로고    scopus 로고
    • Bispecific antibodies and their applications
    • Fan G, Wang Z, Hao M, Li J. Bispecific antibodies and their applications. J Hematol Oncol (2015) 8:130. doi:10.1186/s13045-015-0227-0
    • (2015) J Hematol Oncol , vol.8 , pp. 130
    • Fan, G.1    Wang, Z.2    Hao, M.3    Li, J.4
  • 83
    • 34848850135 scopus 로고    scopus 로고
    • Cytokine-induced killer cells targeted by the novel bispecific antibody CD19xCD5 (HD37xT5.16) efficiently lyse B-lymphoma cells
    • Tita-Nwa F, Moldenhauer G, Herbst M, Kleist C, Ho AD, Kornacker M. Cytokine-induced killer cells targeted by the novel bispecific antibody CD19xCD5 (HD37xT5.16) efficiently lyse B-lymphoma cells. Cancer Immunol Immunother (2007) 56(12):1911-20. doi:10.1007/s00262-007-0333-0
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.12 , pp. 1911-1920
    • Tita-Nwa, F.1    Moldenhauer, G.2    Herbst, M.3    Kleist, C.4    Ho, A.D.5    Kornacker, M.6
  • 84
    • 33645690747 scopus 로고    scopus 로고
    • Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study
    • Chan JK, Hamilton CA, Cheung MK, Karimi M, Baker J, Gall JM, et al. Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study. Clin Cancer Res (2006) 12(6):1859-67. doi:10.1158/1078-0432.CCR-05-2019
    • (2006) Clin Cancer Res , vol.12 , Issue.6 , pp. 1859-1867
    • Chan, J.K.1    Hamilton, C.A.2    Cheung, M.K.3    Karimi, M.4    Baker, J.5    Gall, J.M.6
  • 85
    • 84876491390 scopus 로고    scopus 로고
    • Cytotoxicity of cytokine-induced killer cells targeted by a bispecific antibody to gastric cancer cells
    • Zhang L, Hou Y, Zhang J, Hu J, Zhang K. Cytotoxicity of cytokine-induced killer cells targeted by a bispecific antibody to gastric cancer cells. Oncol Lett (2013) 5(6):1826-32. doi:10.3892/ol.2013.1281
    • (2013) Oncol Lett , vol.5 , Issue.6 , pp. 1826-1832
    • Zhang, L.1    Hou, Y.2    Zhang, J.3    Hu, J.4    Zhang, K.5
  • 86
    • 84883244302 scopus 로고    scopus 로고
    • Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo
    • Huang J, Li C, Wang Y, Lv H, Guo Y, Dai H, et al. Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133(high) cancer stem cells in vitro and in vivo. Clin Immunol (2013) 149(1):156-68. doi:10.1016/j.clim.2013.07.006
    • (2013) Clin Immunol , vol.149 , Issue.1 , pp. 156-168
    • Huang, J.1    Li, C.2    Wang, Y.3    Lv, H.4    Guo, Y.5    Dai, H.6
  • 87
    • 84941956455 scopus 로고    scopus 로고
    • Anti-CD3 x EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro and in vivo
    • Ma P, He Q, Li W, Li X, Han H, Jin M, et al. Anti-CD3 x EGFR bispecific antibody redirects cytokine-induced killer cells to glioblastoma in vitro and in vivo. Oncol Rep (2015) 34(5):2567-75. doi:10.3892/or.2015.4233
    • (2015) Oncol Rep , vol.34 , Issue.5 , pp. 2567-2575
    • Ma, P.1    He, Q.2    Li, W.3    Li, X.4    Han, H.5    Jin, M.6
  • 88
    • 84981285594 scopus 로고    scopus 로고
    • CAR-engineered cytokine-induced killer cells overcome treatment resistance of pre-B-ALL and enhance survival
    • Oelsner S, Wagner J, Friede ME, Pfirrmann V, Genssler S, Rettinger E, et al. CAR-engineered cytokine-induced killer cells overcome treatment resistance of pre-B-ALL and enhance survival. Int J Cancer (2016) 139(8):1799-809. doi:10.1002/ijc.30217
    • (2016) Int J Cancer , vol.139 , Issue.8 , pp. 1799-1809
    • Oelsner, S.1    Wagner, J.2    Friede, M.E.3    Pfirrmann, V.4    Genssler, S.5    Rettinger, E.6
  • 89
    • 33747879963 scopus 로고    scopus 로고
    • Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy
    • Marin V, Dander E, Biagi E, Introna M, Fazio G, Biondi A, et al. Characterization of in vitro migratory properties of anti-CD19 chimeric receptor-redirected CIK cells for their potential use in B-ALL immunotherapy. Exp Hematol (2006) 34(9):1219-29. doi:10.1016/j.exphem.2006.05.004
    • (2006) Exp Hematol , vol.34 , Issue.9 , pp. 1219-1229
    • Marin, V.1    Dander, E.2    Biagi, E.3    Introna, M.4    Fazio, G.5    Biondi, A.6
  • 90
    • 34548129970 scopus 로고    scopus 로고
    • Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-zeta activating signal
    • Marin V, Kakuda H, Dander E, Imai C, Campana D, Biondi A, et al. Enhancement of the anti-leukemic activity of cytokine induced killer cells with an anti-CD19 chimeric receptor delivering a 4-1BB-zeta activating signal. Exp Hematol (2007) 35(9):1388-97. doi:10.1016/j.exphem.2007.05.018
    • (2007) Exp Hematol , vol.35 , Issue.9 , pp. 1388-1397
    • Marin, V.1    Kakuda, H.2    Dander, E.3    Imai, C.4    Campana, D.5    Biondi, A.6
  • 91
    • 84890117209 scopus 로고    scopus 로고
    • Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation"
    • Hombach AA, Rappl G, Abken H. Arming cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation". Mol Ther (2013) 21(12):2268-77. doi:10.1038/mt.2013.192
    • (2013) Mol Ther , vol.21 , Issue.12 , pp. 2268-2277
    • Hombach, A.A.1    Rappl, G.2    Abken, H.3
  • 92
    • 58149165343 scopus 로고    scopus 로고
    • Prospective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancer
    • Wu C, Jiang J, Shi L, Xu N. Prospective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancer. Anticancer Res (2008) 28(6B):3997-4002.
    • (2008) Anticancer Res , vol.28 , Issue.6 B , pp. 3997-4002
    • Wu, C.1    Jiang, J.2    Shi, L.3    Xu, N.4
  • 93
    • 19944426651 scopus 로고    scopus 로고
    • Multidrug resistance-1 (MDR-1): a new target for T cell-based immunotherapy
    • Niethammer AG, Wodrich H, Loeffler M, Lode HN, Emmerich K, Abdollahi A, et al. Multidrug resistance-1 (MDR-1): a new target for T cell-based immunotherapy. FASEB J (2005) 19(1):158-9. doi:10.1096/fj.04-2355fje
    • (2005) FASEB J , vol.19 , Issue.1 , pp. 158-159
    • Niethammer, A.G.1    Wodrich, H.2    Loeffler, M.3    Lode, H.N.4    Emmerich, K.5    Abdollahi, A.6
  • 94
    • 60849131758 scopus 로고    scopus 로고
    • The antitumor effects of CIK cells combined with docetaxel against drug-resistant lung adenocarcinoma cell line SPC-A1/DTX in vitro and in vivo
    • Liu P, Chen L, Huang X. The antitumor effects of CIK cells combined with docetaxel against drug-resistant lung adenocarcinoma cell line SPC-A1/DTX in vitro and in vivo. Cancer Biother Radiopharm (2009) 24(1):91-8. doi:10.1089/cbr.2008.0533
    • (2009) Cancer Biother Radiopharm , vol.24 , Issue.1 , pp. 91-98
    • Liu, P.1    Chen, L.2    Huang, X.3
  • 95
    • 84943637188 scopus 로고    scopus 로고
    • Meta-analysis of chemotherapy and dendritic cells with cytokine-induced killer cells in the treatment of non-small-cell lung cancer
    • Zheng C, Yu G, Wang H, Tang A, Geng P, Zhang H, et al. Meta-analysis of chemotherapy and dendritic cells with cytokine-induced killer cells in the treatment of non-small-cell lung cancer. Int J Clin Exp Med (2015) 8(8):14527-37.
    • (2015) Int J Clin Exp Med , vol.8 , Issue.8 , pp. 14527-14537
    • Zheng, C.1    Yu, G.2    Wang, H.3    Tang, A.4    Geng, P.5    Zhang, H.6
  • 96
    • 84907523487 scopus 로고    scopus 로고
    • Effectiveness and safety of chemotherapy combined with dendritic cells co-cultured with cytokine-induced killer cells in the treatment of advanced non-small-cell lung cancer: a systematic review and meta-analysis
    • Han RX, Liu X, Pan P, Jia YJ, Yu JC. Effectiveness and safety of chemotherapy combined with dendritic cells co-cultured with cytokine-induced killer cells in the treatment of advanced non-small-cell lung cancer: a systematic review and meta-analysis. PLoS One (2014) 9(9):e108958. doi:10.1371/journal.pone.0108958
    • (2014) PLoS One , vol.9 , Issue.9
    • Han, R.X.1    Liu, X.2    Pan, P.3    Jia, Y.J.4    Yu, J.C.5
  • 97
    • 84990065763 scopus 로고    scopus 로고
    • Effectiveness and safety of chemotherapy combined with cytokine-induced killer cell/dendritic cell-cytokine-induced killer cell therapy for treatment of gastric cancer in China: a systematic review and meta-analysis
    • Mu Y, Zhou CH, Chen SF, Ding J, Zhang YX, Yang YP, et al. Effectiveness and safety of chemotherapy combined with cytokine-induced killer cell/dendritic cell-cytokine-induced killer cell therapy for treatment of gastric cancer in China: a systematic review and meta-analysis. Cytotherapy (2016) 18(9):1162-77. doi:10.1016/j.jcyt.2016.05.015
    • (2016) Cytotherapy , vol.18 , Issue.9 , pp. 1162-1177
    • Mu, Y.1    Zhou, C.H.2    Chen, S.F.3    Ding, J.4    Zhang, Y.X.5    Yang, Y.P.6
  • 98
    • 84892989079 scopus 로고    scopus 로고
    • Combination of chemotherapy and immunotherapy for colon cancer in China: a meta-analysis
    • Wang ZX, Cao JX, Liu ZP, Cui YX, Li CY, Li D, et al. Combination of chemotherapy and immunotherapy for colon cancer in China: a meta-analysis. World J Gastroenterol (2014) 20(4):1095-106. doi:10.3748/wjg.v20.i4.1095
    • (2014) World J Gastroenterol , vol.20 , Issue.4 , pp. 1095-1106
    • Wang, Z.X.1    Cao, J.X.2    Liu, Z.P.3    Cui, Y.X.4    Li, C.Y.5    Li, D.6
  • 99
    • 84994477358 scopus 로고    scopus 로고
    • Emerging nanomedicine approaches fighting tumor metastasis: animal models, metastasis-targeted drug delivery, phototherapy, and immunotherapy
    • Liang C, Xu L, Song G, Liu Z. Emerging nanomedicine approaches fighting tumor metastasis: animal models, metastasis-targeted drug delivery, phototherapy, and immunotherapy. Chem Soc Rev (2016) 45(22):6250-69. doi:10.1039/c6cs00458j
    • (2016) Chem Soc Rev , vol.45 , Issue.22 , pp. 6250-6269
    • Liang, C.1    Xu, L.2    Song, G.3    Liu, Z.4
  • 100
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: opportunities and challenges
    • Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer (2005) 5(3):161-71. doi:10.1038/nrc1566
    • (2005) Nat Rev Cancer , vol.5 , Issue.3 , pp. 161-171
    • Ferrari, M.1
  • 101
    • 65549115157 scopus 로고    scopus 로고
    • Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment
    • Phan JH, Moffitt RA, Stokes TH, Liu J, Young AN, Nie S, et al. Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotechnol (2009) 27(6):350-8. doi:10.1016/j.tibtech.2009.02.010
    • (2009) Trends Biotechnol , vol.27 , Issue.6 , pp. 350-358
    • Phan, J.H.1    Moffitt, R.A.2    Stokes, T.H.3    Liu, J.4    Young, A.N.5    Nie, S.6
  • 102
    • 33746319850 scopus 로고    scopus 로고
    • Emerging implications of nanotechnology on cancer diagnostics and therapeutics
    • Cuenca AG, Jiang H, Hochwald SN, Delano M, Cance WG, Grobmyer SR. Emerging implications of nanotechnology on cancer diagnostics and therapeutics. Cancer (2006) 107(3):459-66. doi:10.1002/cncr.22035
    • (2006) Cancer , vol.107 , Issue.3 , pp. 459-466
    • Cuenca, A.G.1    Jiang, H.2    Hochwald, S.N.3    Delano, M.4    Cance, W.G.5    Grobmyer, S.R.6
  • 103
    • 85006987142 scopus 로고    scopus 로고
    • Cancer nano-immunoengineering: the marriage of immunoengineering and nanotechnology for cancer
    • Jin W, Cui D. Cancer nano-immunoengineering: the marriage of immunoengineering and nanotechnology for cancer. Nano Biomed Eng (2016) 8(2):105-6. doi:10.5101/nbe.v8i2.p105-107
    • (2016) Nano Biomed Eng , vol.8 , Issue.2 , pp. 105-106
    • Jin, W.1    Cui, D.2
  • 104
    • 47049099053 scopus 로고    scopus 로고
    • Multifunctional nanoparticles-properties and prospects for their use in human medicine
    • Sanvicens N, Marco MP. Multifunctional nanoparticles - properties and prospects for their use in human medicine. Trends Biotechnol (2008) 26(8):425-33. doi:10.1016/j.tibtech.2008.04.005
    • (2008) Trends Biotechnol , vol.26 , Issue.8 , pp. 425-433
    • Sanvicens, N.1    Marco, M.P.2
  • 105
    • 33746648133 scopus 로고    scopus 로고
    • Emerging use of nanoparticles in diagnosis and treatment of breast cancer
    • Yezhelyev MV, Gao X, Xing Y, Al-Hajj A, Nie S, O'Regan RM. Emerging use of nanoparticles in diagnosis and treatment of breast cancer. Lancet Oncol (2006) 7(8):657-67. doi:10.1016/S1470-2045(06)70793-8
    • (2006) Lancet Oncol , vol.7 , Issue.8 , pp. 657-667
    • Yezhelyev, M.V.1    Gao, X.2    Xing, Y.3    Al-Hajj, A.4    Nie, S.5    O'Regan, R.M.6
  • 107
    • 33644752699 scopus 로고    scopus 로고
    • Nanomedicine for respiratory diseases
    • Pison U, Welte T, Giersig M, Groneberg DA. Nanomedicine for respiratory diseases. Eur J Pharmacol (2006) 533(1-3):341-50. doi:10.1016/j.ejphar.2005.12.068
    • (2006) Eur J Pharmacol , vol.533 , Issue.1-3 , pp. 341-350
    • Pison, U.1    Welte, T.2    Giersig, M.3    Groneberg, D.A.4
  • 108
    • 84942685991 scopus 로고    scopus 로고
    • Synthetic nanoparticles for vaccines and immunotherapy
    • Irvine DJ, Hanson MC, Rakhra K, Tokatlian T. Synthetic nanoparticles for vaccines and immunotherapy. Chem Rev (2015) 115(19):11109-46. doi:10.1021/acs.chemrev.5b00109
    • (2015) Chem Rev , vol.115 , Issue.19 , pp. 11109-11146
    • Irvine, D.J.1    Hanson, M.C.2    Rakhra, K.3    Tokatlian, T.4
  • 109
    • 84959567353 scopus 로고    scopus 로고
    • Recent advances in the development of nanomaterials for DC-based immunotherapy
    • Xu LG, Xiang J, Peng R, Liu Z. Recent advances in the development of nanomaterials for DC-based immunotherapy. Sci Bull (2016) 61(7):514-23. doi:10.1007/s11434-016-1038-6
    • (2016) Sci Bull , vol.61 , Issue.7 , pp. 514-523
    • Xu, L.G.1    Xiang, J.2    Peng, R.3    Liu, Z.4
  • 110
    • 34248228113 scopus 로고    scopus 로고
    • Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells
    • Cambi A, Lidke DS, Arndt-Jovin DJ, Figdor CG, Jovin TM. Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells. Nano Lett (2007) 7(4):970-7. doi:10.1021/nl0700503
    • (2007) Nano Lett , vol.7 , Issue.4 , pp. 970-977
    • Cambi, A.1    Lidke, D.S.2    Arndt-Jovin, D.J.3    Figdor, C.G.4    Jovin, T.M.5
  • 111
    • 55349132044 scopus 로고    scopus 로고
    • Biocompatible polymer-nanoparticle-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells
    • Lim YT, Noh YW, Han JH, Cai QY, Yoon KH, Chung BH. Biocompatible polymer-nanoparticle-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells. Small (2008) 4(10):1640-5. doi:10.1002/smll.200800582
    • (2008) Small , vol.4 , Issue.10 , pp. 1640-1645
    • Lim, Y.T.1    Noh, Y.W.2    Han, J.H.3    Cai, Q.Y.4    Yoon, K.H.5    Chung, B.H.6
  • 112
    • 58149292274 scopus 로고    scopus 로고
    • Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation
    • Reichardt W, Durr C, von Elverfeldt D, Juttner E, Gerlach UV, Yamada M, et al. Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation. J Immunol (2008) 181(7):4770-9. doi:10.4049/jimmunol.181.7.4770
    • (2008) J Immunol , vol.181 , Issue.7 , pp. 4770-4779
    • Reichardt, W.1    Durr, C.2    von Elverfeldt, D.3    Juttner, E.4    Gerlach, U.V.5    Yamada, M.6
  • 113
    • 66149142268 scopus 로고    scopus 로고
    • Magnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes
    • Long CM, van Laarhoven HWM, Bulte JWM, Levitsky HI. Magnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes. Cancer Res (2009) 69(7):3180-7. doi:10.1158/0008-5472.CAN-08-3691
    • (2009) Cancer Res , vol.69 , Issue.7 , pp. 3180-3187
    • Long, C.M.1    van Laarhoven, H.W.M.2    Bulte, J.W.M.3    Levitsky, H.I.4
  • 114
    • 79953820808 scopus 로고    scopus 로고
    • Multimodal imaging of nanovaccine carriers targeted to human dendritic cells
    • Cruz LJ, Tacken PJ, Bonetto F, Buschow SI, Croes HJ, Wijers M, et al. Multimodal imaging of nanovaccine carriers targeted to human dendritic cells. Mol Pharm (2011) 8(2):520-31. doi:10.1021/mp100356k
    • (2011) Mol Pharm , vol.8 , Issue.2 , pp. 520-531
    • Cruz, L.J.1    Tacken, P.J.2    Bonetto, F.3    Buschow, S.I.4    Croes, H.J.5    Wijers, M.6
  • 115
    • 84935024404 scopus 로고    scopus 로고
    • Antigen-loaded upconversion nanoparticles for dendritic cell stimulation, tracking, and vaccination in dendritic cell-based immunotherapy
    • Xiang J, Xu LG, Gong H, Zhu WW, Wang C, Xu J, et al. Antigen-loaded upconversion nanoparticles for dendritic cell stimulation, tracking, and vaccination in dendritic cell-based immunotherapy. ACS Nano (2015) 9(6):6401-11. doi:10.1021/acsnano.5b02014
    • (2015) ACS Nano , vol.9 , Issue.6 , pp. 6401-6411
    • Xiang, J.1    Xu, L.G.2    Gong, H.3    Zhu, W.W.4    Wang, C.5    Xu, J.6
  • 116
    • 84895423822 scopus 로고    scopus 로고
    • Nanoparticle-based vaccine delivery for cancer immunotherapy
    • Park YM, Lee SJ, Kim YS, Lee MH, Cha GS, Jung ID, et al. Nanoparticle-based vaccine delivery for cancer immunotherapy. Immune Netw (2013) 13(5):177-83. doi:10.4110/in.2013.13.5.177
    • (2013) Immune Netw , vol.13 , Issue.5 , pp. 177-183
    • Park, Y.M.1    Lee, S.J.2    Kim, Y.S.3    Lee, M.H.4    Cha, G.S.5    Jung, I.D.6
  • 118
    • 84878893034 scopus 로고    scopus 로고
    • Methods of effective conjugation of antigens to nanoparticles as non-inflammatory vaccine carriers
    • Xiang SD, Wilson K, Day S, Fuchsberger M, Plebanski M. Methods of effective conjugation of antigens to nanoparticles as non-inflammatory vaccine carriers. Methods (2013) 60(3):232-41. doi:10.1016/j.ymeth.2013.03.036
    • (2013) Methods , vol.60 , Issue.3 , pp. 232-241
    • Xiang, S.D.1    Wilson, K.2    Day, S.3    Fuchsberger, M.4    Plebanski, M.5
  • 120
    • 84924611985 scopus 로고    scopus 로고
    • Cytokine-induced killer (CIK) cells: from basic research to clinical translation
    • Guo Y, Han W. Cytokine-induced killer (CIK) cells: from basic research to clinical translation. Chin J Cancer (2015) 34(3):99-107. doi:10.1186/s40880-015-0002-1
    • (2015) Chin J Cancer , vol.34 , Issue.3 , pp. 99-107
    • Guo, Y.1    Han, W.2
  • 121
    • 84930018607 scopus 로고    scopus 로고
    • Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma
    • Lee JH, Lim YS, Yeon JE, Song TJ, Yu SJ, Gwak GY, et al. Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma. Gastroenterology (2015) 148(7):1383-91.e6. doi:10.1053/j.gastro.2015.02.055
    • (2015) Gastroenterology , vol.148 , Issue.7 , pp. 1383-1391
    • Lee, J.H.1    Lim, Y.S.2    Yeon, J.E.3    Song, T.J.4    Yu, S.J.5    Gwak, G.Y.6
  • 122
    • 40749152776 scopus 로고    scopus 로고
    • Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas
    • Weng DS, Zhou J, Zhou QM, Zhao M, Wang QJ, Huang LX, et al. Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas. J Immunother (2008) 31(1):63-71. doi:10.1097/CJI.0b013e31815a121b
    • (2008) J Immunother , vol.31 , Issue.1 , pp. 63-71
    • Weng, D.S.1    Zhou, J.2    Zhou, Q.M.3    Zhao, M.4    Wang, Q.J.5    Huang, L.X.6
  • 123
    • 57449105089 scopus 로고    scopus 로고
    • A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma
    • Hui D, Qiang L, Jian W, Ti Z, Da-Lu K. A randomized, controlled trial of postoperative adjuvant cytokine-induced killer cells immunotherapy after radical resection of hepatocellular carcinoma. Dig Liver Dis (2009) 41(1):36-41. doi:10.1016/j.dld.2008.04.007
    • (2009) Dig Liver Dis , vol.41 , Issue.1 , pp. 36-41
    • Hui, D.1    Qiang, L.2    Jian, W.3    Ti, Z.4    Da-Lu, K.5
  • 124
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial
    • Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, et al. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet (2000) 356(9232):802-7. doi:10.1016/S0140-6736(00)02654-4
    • (2000) Lancet , vol.356 , Issue.9232 , pp. 802-807
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3    Yamasaki, S.4    Kosuge, T.5    Yamamoto, J.6
  • 125
    • 84930018607 scopus 로고    scopus 로고
    • Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma
    • Lee JH, Lee JH, Lim YS, Yeon JE, Song TJ, Yu SJ, et al. Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma. Gastroenterology (2015) 148(7):1383-91. doi:10.1053/j.gastro.2015.02.055
    • (2015) Gastroenterology , vol.148 , Issue.7 , pp. 1383-1391
    • Lee, J.H.1    Lee, J.H.2    Lim, Y.S.3    Yeon, J.E.4    Song, T.J.5    Yu, S.J.6
  • 126
    • 84992497184 scopus 로고    scopus 로고
    • Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma patients after curative resection, a systemic review and meta-analysis
    • Wang H, Liu A, Bo W, Feng X, Hu Y, Tian L, et al. Adjuvant immunotherapy with autologous cytokine-induced killer cells for hepatocellular carcinoma patients after curative resection, a systemic review and meta-analysis. Dig Liver Dis (2016) 48(11):1275-82. doi:10.1016/j.dld.2016.07.010
    • (2016) Dig Liver Dis , vol.48 , Issue.11 , pp. 1275-1282
    • Wang, H.1    Liu, A.2    Bo, W.3    Feng, X.4    Hu, Y.5    Tian, L.6
  • 127
    • 84865055267 scopus 로고    scopus 로고
    • Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review
    • Xie F, Zhang X, Li H, Zheng T, Xu F, Shen R, et al. Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review. PLoS One (2012) 7(8):e42879. doi:10.1371/journal.pone.0042879
    • (2012) PLoS One , vol.7 , Issue.8
    • Xie, F.1    Zhang, X.2    Li, H.3    Zheng, T.4    Xu, F.5    Shen, R.6
  • 128
    • 84912530810 scopus 로고    scopus 로고
    • A meta-analysis of cytokine-induced killer cells therapy in combination with minimally invasive treatment for hepatocellular carcinoma
    • Li X, Dai D, Song X, Liu J, Zhu L, Xu W. A meta-analysis of cytokine-induced killer cells therapy in combination with minimally invasive treatment for hepatocellular carcinoma. Clin Res Hepatol Gastroenterol (2014) 38(5):583-91. doi:10.1016/j.clinre.2014.04.010
    • (2014) Clin Res Hepatol Gastroenterol , vol.38 , Issue.5 , pp. 583-591
    • Li, X.1    Dai, D.2    Song, X.3    Liu, J.4    Zhu, L.5    Xu, W.6
  • 129
    • 84878029051 scopus 로고    scopus 로고
    • Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety
    • Ma Y, Xu YC, Tang L, Zhang Z, Wang J, Wang HX. Cytokine-induced killer (CIK) cell therapy for patients with hepatocellular carcinoma: efficacy and safety. Exp Hematol Oncol (2012) 1(1):11. doi:10.1186/2162-3619-1-11
    • (2012) Exp Hematol Oncol , vol.1 , Issue.1 , pp. 11
    • Ma, Y.1    Xu, Y.C.2    Tang, L.3    Zhang, Z.4    Wang, J.5    Wang, H.X.6
  • 130
    • 84870975640 scopus 로고    scopus 로고
    • Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study
    • Li R, Wang C, Liu L, Du C, Cao S, Yu J, et al. Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study. Cancer Immunol Immunother (2012) 61(11):2125-33. doi:10.1007/s00262-012-1260-2
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.11 , pp. 2125-2133
    • Li, R.1    Wang, C.2    Liu, L.3    Du, C.4    Cao, S.5    Yu, J.6
  • 131
    • 84955650399 scopus 로고    scopus 로고
    • Tumor MICA status predicts the efficacy of immunotherapy with cytokine-induced killer cells for patients with gastric cancer
    • Chen Y, Lin WS, Zhu WF, Lin J, Zhou ZF, Huang CZ, et al. Tumor MICA status predicts the efficacy of immunotherapy with cytokine-induced killer cells for patients with gastric cancer. Immunol Res (2016) 64(1):251-9. doi:10.1007/s12026-015-8743-0
    • (2016) Immunol Res , vol.64 , Issue.1 , pp. 251-259
    • Chen, Y.1    Lin, W.S.2    Zhu, W.F.3    Lin, J.4    Zhou, Z.F.5    Huang, C.Z.6
  • 132
    • 85006219671 scopus 로고    scopus 로고
    • MHC I-related chain a expression in gastric carcinoma and the efficacy of immunotherapy with cytokine-induced killer cells
    • Chen Y, Lin J, Guo ZQ, Lin WS, Zhou ZF, Huang CZ, et al. MHC I-related chain a expression in gastric carcinoma and the efficacy of immunotherapy with cytokine-induced killer cells. Am J Cancer Res (2015) 5(10):3221-30.
    • (2015) Am J Cancer Res , vol.5 , Issue.10 , pp. 3221-3230
    • Chen, Y.1    Lin, J.2    Guo, Z.Q.3    Lin, W.S.4    Zhou, Z.F.5    Huang, C.Z.6
  • 133
    • 84997503437 scopus 로고    scopus 로고
    • Phase II/III study of radiofrequency ablation combined with cytokine-induced killer cells treating colorectal liver metastases
    • Li X, Dai X, Shi L, Jiang Y, Chen X, Chen L, et al. Phase II/III study of radiofrequency ablation combined with cytokine-induced killer cells treating colorectal liver metastases. Cell Physiol Biochem (2016) 40(1-2):137-45. doi:10.1159/000452531
    • (2016) Cell Physiol Biochem , vol.40 , Issue.1-2 , pp. 137-145
    • Li, X.1    Dai, X.2    Shi, L.3    Jiang, Y.4    Chen, X.5    Chen, L.6
  • 134
    • 84911917654 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cytokine-induced killer cell therapy in the treatment of non-small cell lung cancer
    • Wang M, Cao JX, Pan JH, Liu YS, Xu BL, Li D, et al. Adoptive immunotherapy of cytokine-induced killer cell therapy in the treatment of non-small cell lung cancer. PLoS One (2014) 9(11):e112662. doi:10.1371/journal.pone.0112662
    • (2014) PLoS One , vol.9 , Issue.11
    • Wang, M.1    Cao, J.X.2    Pan, J.H.3    Liu, Y.S.4    Xu, B.L.5    Li, D.6
  • 135
    • 84906268885 scopus 로고    scopus 로고
    • Impact of cellular immune function on prognosis of lung cancer patients after cytokine-induced killer cell therapy
    • Jin C, Li J, Wang Y, Chen X, Che Y, Liu X, et al. Impact of cellular immune function on prognosis of lung cancer patients after cytokine-induced killer cell therapy. Asian Pac J Cancer Prev (2014) 15(15):6009-14. doi:10.7314/APJCP.2014.15.15.6009
    • (2014) Asian Pac J Cancer Prev , vol.15 , Issue.15 , pp. 6009-6014
    • Jin, C.1    Li, J.2    Wang, Y.3    Chen, X.4    Che, Y.5    Liu, X.6
  • 136
    • 84896829817 scopus 로고    scopus 로고
    • Effects of a gemcitabine plus platinum regimen combined with a dendritic cell-cytokine induced killer immunotherapy on recurrence and survival rate of non-small cell lung cancer patients
    • Zhao M, Li H, Li L, Zhang Y. Effects of a gemcitabine plus platinum regimen combined with a dendritic cell-cytokine induced killer immunotherapy on recurrence and survival rate of non-small cell lung cancer patients. Exp Ther Med (2014) 7(5):1403-7. doi:10.3892/etm.2014.1574
    • (2014) Exp Ther Med , vol.7 , Issue.5 , pp. 1403-1407
    • Zhao, M.1    Li, H.2    Li, L.3    Zhang, Y.4
  • 137
    • 84927516392 scopus 로고    scopus 로고
    • Autologous cytokine-induced killer cell therapy in lung cancer patients: a retrospective study
    • Zhang J, Zhu L, Du H, He X, Yin Y, Gu Y, et al. Autologous cytokine-induced killer cell therapy in lung cancer patients: a retrospective study. Biomed Pharmacother (2015) 70:248-52. doi:10.1016/j.biopha.2014.12.025
    • (2015) Biomed Pharmacother , vol.70 , pp. 248-252
    • Zhang, J.1    Zhu, L.2    Du, H.3    He, X.4    Yin, Y.5    Gu, Y.6
  • 138
    • 84960438772 scopus 로고    scopus 로고
    • Dendritic cell vaccine and cytokine-induced killer cell therapy for the treatment of advanced non-small cell lung cancer
    • Zhang L, Yang X, Sun Z, Li J, Zhu H, Li J, et al. Dendritic cell vaccine and cytokine-induced killer cell therapy for the treatment of advanced non-small cell lung cancer. Oncol Lett (2016) 11(4):2605-10. doi:10.3892/ol.2016.4273
    • (2016) Oncol Lett , vol.11 , Issue.4 , pp. 2605-2610
    • Zhang, L.1    Yang, X.2    Sun, Z.3    Li, J.4    Zhu, H.5    Li, J.6
  • 139
    • 84961842662 scopus 로고    scopus 로고
    • Evaluation of 29 indicators for the prognosis of advanced non-small cell lung cancer with cytokine-induced killer cell therapy combined with chemotherapy
    • Jia H, Tian Y, Jiang CG, Han W. Evaluation of 29 indicators for the prognosis of advanced non-small cell lung cancer with cytokine-induced killer cell therapy combined with chemotherapy. Exp Ther Med (2016) 11(5):1601-10. doi:10.3892/etm.2016.3102
    • (2016) Exp Ther Med , vol.11 , Issue.5 , pp. 1601-1610
    • Jia, H.1    Tian, Y.2    Jiang, C.G.3    Han, W.4
  • 140
    • 84977107171 scopus 로고    scopus 로고
    • Autologous cytokine-induced killer cells improves overall survival of metastatic colorectal cancer patients: results from a phase II clinical trial
    • Zhao H, Wang Y, Yu J, Wei F, Cao S, Zhang X, et al. Autologous cytokine-induced killer cells improves overall survival of metastatic colorectal cancer patients: results from a phase II clinical trial. Clin Colorectal Cancer (2016) 15(3):228-35. doi:10.1016/j.clcc.2016.02.005
    • (2016) Clin Colorectal Cancer , vol.15 , Issue.3 , pp. 228-235
    • Zhao, H.1    Wang, Y.2    Yu, J.3    Wei, F.4    Cao, S.5    Zhang, X.6
  • 141
    • 84945151804 scopus 로고    scopus 로고
    • Clinical effects of autologous dendritic cells combined with cytokine-induced killer cells followed by chemotherapy in treating patients with advanced colorectal cancer: a prospective study
    • Lin T, Song C, Chuo DY, Zhang H, Zhao J. Clinical effects of autologous dendritic cells combined with cytokine-induced killer cells followed by chemotherapy in treating patients with advanced colorectal cancer: a prospective study. Tumour Biol (2016) 37(4):4367-72. doi:10.1007/s13277-015-3957-2
    • (2016) Tumour Biol , vol.37 , Issue.4 , pp. 4367-4372
    • Lin, T.1    Song, C.2    Chuo, D.Y.3    Zhang, H.4    Zhao, J.5
  • 142
    • 85010747968 scopus 로고    scopus 로고
    • Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea
    • Kong DS, Nam DH, Kang SH, Lee JW, Chang JH, Kim JH, et al. Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in Korea. Oncotarget (2016) 8(4):7003-13. doi:10.18632/oncotarget.12273
    • (2016) Oncotarget , vol.8 , Issue.4 , pp. 7003-7013
    • Kong, D.S.1    Nam, D.H.2    Kang, S.H.3    Lee, J.W.4    Chang, J.H.5    Kim, J.H.6
  • 143
    • 84997542995 scopus 로고    scopus 로고
    • Selective effect of cytokine-induced killer cells on survival of patients with early-stage melanoma
    • Li H, Huang L, Liu LB, Wang XM, Zhang Z, Yue DL, et al. Selective effect of cytokine-induced killer cells on survival of patients with early-stage melanoma. Cancer Immunol Immunother (2017) 66(3):299-308. doi:10.1007/s00262-016-1939-x
    • (2017) Cancer Immunol Immunother , vol.66 , Issue.3 , pp. 299-308
    • Li, H.1    Huang, L.2    Liu, L.B.3    Wang, X.M.4    Zhang, Z.5    Yue, D.L.6
  • 145
    • 84875282081 scopus 로고    scopus 로고
    • Cytokine-induced killer cells promote antitumor immunity
    • Jiang J, Wu C, Lu B. Cytokine-induced killer cells promote antitumor immunity. J Transl Med (2013) 11:83. doi:10.1186/1479-5876-11-83
    • (2013) J Transl Med , vol.11 , pp. 83
    • Jiang, J.1    Wu, C.2    Lu, B.3
  • 146
    • 84962840922 scopus 로고    scopus 로고
    • Combination cancer therapies with immune checkpoint blockade: convergence on interferon signaling
    • Minn AJ, Wherry EJ. Combination cancer therapies with immune checkpoint blockade: convergence on interferon signaling. Cell (2016) 165(2):272-5. doi:10.1016/j.cell.2016.03.031
    • (2016) Cell , vol.165 , Issue.2 , pp. 272-275
    • Minn, A.J.1    Wherry, E.J.2
  • 147
    • 84944061705 scopus 로고    scopus 로고
    • Smart CARs engineered for cancer immunotherapy
    • Priceman SJ, Forman SJ, Brown CE. Smart CARs engineered for cancer immunotherapy. Curr Opin Oncol (2015) 27(6):466-74. doi:10.1097/CCO.0000000000000232
    • (2015) Curr Opin Oncol , vol.27 , Issue.6 , pp. 466-474
    • Priceman, S.J.1    Forman, S.J.2    Brown, C.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.