-
2
-
-
84855520803
-
Cytokine induced killer cells as promising immunotherapy for solid tumors
-
Sangiolo D. Cytokine induced killer cells as promising immunotherapy for solid tumors. J Cancer 2011;2:363-8
-
(2011)
J Cancer
, vol.2
, pp. 363-368
-
-
Sangiolo, D.1
-
3
-
-
77955509674
-
IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy
-
Helms MW, Prescher JA, Cao YA, et al. IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy. Cancer Immunol Immunother 2010;59:1325-34
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1325-1334
-
-
Helms, M.W.1
Prescher, J.A.2
Cao, Y.A.3
-
4
-
-
77951691641
-
Cytokine-induced NK-like T cells: From bench to bedside
-
Linn YC, Hui KM. Cytokine-induced NK-like T cells: from bench to bedside. J Biomed Biotechnol 2010;2010:435745
-
(2010)
J Biomed Biotechnol
, vol.2010
, pp. 435745
-
-
Linn, Y.C.1
Hui, K.M.2
-
5
-
-
0027860412
-
Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells
-
Schmidt-Wolf IG, Lefterova P, Mehta BA, et al. Phenotypic characterization and identification of effector cells involved in tumor cell recognition of cytokine-induced killer cells. Exp Hematol 1993;21:1673-9 (Pubitemid 24223014)
-
(1993)
Experimental Hematology
, vol.21
, Issue.13
, pp. 1673-1679
-
-
Schmidt-Wolf, I.G.H.1
Lefterova, P.2
Mehta, B.A.3
Fernandez, L.P.4
Huhn, D.5
Blume, K.G.6
Weissman, I.L.7
Negrin, R.S.8
-
6
-
-
0028874988
-
Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells
-
Mehta BA, Schmidt-Wolf IG, Weissman IL, et al. Two pathways of exocytosis of cytoplasmic granule contents and target cell killing by cytokine-induced CD3+ CD56+ killer cells. Blood 1995;86:3493-9
-
(1995)
Blood
, vol.86
, pp. 3493-3499
-
-
Mehta, B.A.1
Schmidt-Wolf, I.G.2
Weissman, I.L.3
-
7
-
-
0025856106
-
Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
-
The first report on ex vivo generation of CIK cells that revealed cytolytic activity against human lymphoma cell line in vivo
-
Schmidt-Wolf IG, Negrin RS, Kiem HP, et al. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J Exp Med 1991;174:139-49 The first report on ex vivo generation of CIK cells that revealed cytolytic activity against human lymphoma cell line in vivo.
-
(1991)
J Exp Med
, vol.174
, pp. 139-149
-
-
Schmidt-Wolf, I.G.1
Negrin, R.S.2
Kiem, H.P.3
-
8
-
-
55249095629
-
In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity
-
Nishimura R, Baker J, Beilhack A, et al. In vivo trafficking and survival of cytokine-induced killer cells resulting in minimal GVHD with retention of antitumor activity. Blood 2008;112:2563-74
-
(2008)
Blood
, vol.112
, pp. 2563-2574
-
-
Nishimura, R.1
Baker, J.2
Beilhack, A.3
-
9
-
-
0028301366
-
Propagation of large numbers of T cells with natural killer cell markers
-
This manuscript is groundbreaking for the generation of large amounts of CIK cells. The timed addition of IFN-γ, IL-1, IL-2 and an mAb against CD3 leads to a massive expansion of CIK cells
-
Schmidt-Wolf IG, Lefterova P, Johnston V, et al. Propagation of large numbers of T cells with natural killer cell markers. Br J Haematol 1994;87:453-8 This manuscript is groundbreaking for the generation of large amounts of CIK cells. The timed addition of IFN-γ, IL-1, IL-2 and an mAb against CD3 leads to a massive expansion of CIK cells.
-
(1994)
Br J Haematol
, vol.87
, pp. 453-458
-
-
Schmidt-Wolf, I.G.1
Lefterova, P.2
Johnston, V.3
-
10
-
-
0032433319
-
Generation of cytokine-induced killer cells using exogenous interleukin- 2, -7 or-12
-
DOI 10.1007/s002620050524
-
Zoll B, Lefterova P, Csipai M, et al. Generation of cytokine-induced killer cells using exogenous interleukin-2, -7 or -12. Cancer Immunol Immunother 1998;47:221-6 (Pubitemid 29009677)
-
(1998)
Cancer Immunology Immunotherapy
, vol.47
, Issue.4
, pp. 221-226
-
-
Zoll, B.1
Lefterova, P.2
Csipai, M.3
Finke, S.4
Trojaneck, B.5
Ebert, O.6
Micka, B.7
Roigk, K.8
Fehlinger, M.9
Schmidt-Wolf, G.D.10
Huhn, D.11
Schmidt-Wolf, I.G.H.12
-
11
-
-
79251579272
-
Growth of human colorectal cancer SW1116 cells is inhibited by cytokine-induced killer cells
-
Wang Y, Dai H, Li H, et al. Growth of human colorectal cancer SW1116 cells is inhibited by cytokine-induced killer cells. Clin Dev Immunol 2011;2011:621414
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 621414
-
-
Wang, Y.1
Dai, H.2
Li, H.3
-
12
-
-
78751543653
-
Adoptive immunotherapy of human gastric cancer with ex vivo expanded T cells
-
Kim YJ, Lim J, Kang JS, et al. Adoptive immunotherapy of human gastric cancer with ex vivo expanded T cells. Arch Pharm Res 2010;33:1789-95
-
(2010)
Arch Pharm Res
, vol.33
, pp. 1789-1795
-
-
Kim, Y.J.1
Lim, J.2
Kang, J.S.3
-
13
-
-
67649373027
-
Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model
-
Kim HM, Kang JS, Lim J, et al. Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model. Arch Pharm Res 2009;32:781-7
-
(2009)
Arch Pharm Res
, vol.32
, pp. 781-787
-
-
Kim, H.M.1
Kang, J.S.2
Lim, J.3
-
14
-
-
35848940733
-
Antitumor activity of cytokine-induced killer cells against human lung cancer
-
DOI 10.1016/j.intimp.2007.08.016, PII S1567576907002615
-
Kim HM, Lim J, Park SK, et al. Antitumor activity of cytokine-induced killer cells against human lung cancer. Int Immunopharmacol 2007;7:1802-7 (Pubitemid 350054928)
-
(2007)
International Immunopharmacology
, vol.7
, Issue.13
, pp. 1802-1807
-
-
Kim, H.M.1
Lim, J.2
Park, S.-K.3
Kang, J.S.4
Lee, K.5
Lee, C.W.6
Lee, K.H.7
Yun, M.-J.8
Yang, K.-H.9
Han, G.10
Kwon, S.W.11
Kim, Y.12
Han, S.-B.13
-
15
-
-
2342437804
-
Autologous cytokine-induced killer cell therapy in clinical trial phase I is safe in patients with primary hepatocellular carcinoma
-
Shi M, Zhang B, Tang ZR, et al. Autologous cytokine-induced killer cell therapy in clinical trial phase I is safe in patients with primary hepatocellular carcinoma. World J Gastroenterol 2004;10:1146-51 (Pubitemid 38559390)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.8
, pp. 1146-1151
-
-
Shi, M.1
Zhang, B.2
Tang, Z.-R.3
Lei, Z.-Y.4
Wang, H.-F.5
Feng, Y.-Y.6
Fan, Z.-P.7
Xu, D.-P.8
Wang, F.-S.9
-
16
-
-
77956169022
-
Immunotherapy with cytokine-induced killer cells in metastatic renal cell carcinoma
-
Su X, Zhang L, Jin L, et al. Immunotherapy with cytokine-induced killer cells in metastatic renal cell carcinoma. Cancer Biother Radiopharm 2010;25:465-70
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 465-470
-
-
Su, X.1
Zhang, L.2
Jin, L.3
-
17
-
-
67650360317
-
Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: A pilot clinical trial
-
Olioso P, Giancola R, Di Riti M, et al. Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: a pilot clinical trial. Hematol Oncol 2009;27:130-9
-
(2009)
Hematol Oncol
, vol.27
, pp. 130-139
-
-
Olioso, P.1
Giancola, R.2
Di Riti, M.3
-
18
-
-
78650721870
-
Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma
-
Jin J, Joo KM, Lee SJ, et al. Synergistic therapeutic effects of cytokine-induced killer cells and temozolomide against glioblastoma. Oncol Rep 2011;25:33-9
-
(2011)
Oncol Rep
, vol.25
, pp. 33-39
-
-
Jin, J.1
Joo, K.M.2
Lee, S.J.3
-
19
-
-
60849131758
-
The antitumor effects of CIK cells combined with docetaxel against drug-resistant lung adenocarcinoma cell line SPC-A1/DTX in vitro and in vivo
-
Liu P, Chen L, Huang X. The antitumor effects of CIK cells combined with docetaxel against drug-resistant lung adenocarcinoma cell line SPC-A1/DTX in vitro and in vivo. Cancer Biother Radiopharm 2009;24:91-8
-
(2009)
Cancer Biother Radiopharm
, vol.24
, pp. 91-98
-
-
Liu, P.1
Chen, L.2
Huang, X.3
-
20
-
-
79960204729
-
Cisplatin pretreatment enhances anti-tumor activity of cytokine-induced killer cells
-
Huang X, Chen YT, Song HZ, et al. Cisplatin pretreatment enhances anti-tumor activity of cytokine-induced killer cells. World J Gastroenterol 2011;17:3002-11
-
(2011)
World J Gastroenterol
, vol.17
, pp. 3002-3011
-
-
Huang, X.1
Chen, Y.T.2
Song, H.Z.3
-
21
-
-
78650799848
-
Increasing the frequency of CIK cells adoptive immunotherapy may decrease risk of death in gastric cancer patients
-
Jiang JT, Shen YP, Wu CP, et al. Increasing the frequency of CIK cells adoptive immunotherapy may decrease risk of death in gastric cancer patients. World J Gastroenterol 2010;16:6155-62
-
(2010)
World J Gastroenterol
, vol.16
, pp. 6155-6162
-
-
Jiang, J.T.1
Shen, Y.P.2
Wu, C.P.3
-
22
-
-
58149165343
-
Prospective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancer
-
A description of combing CIK cells with conventional chemotherapy in advanced NSCLC leading to longer PFS and OS
-
Wu C, Jiang J, Shi L, et al. Prospective study of chemotherapy in combination with cytokine-induced killer cells in patients suffering from advanced non-small cell lung cancer. Anticancer Res 2008;28:3997-4002 A description of combing CIK cells with conventional chemotherapy in advanced NSCLC leading to longer PFS and OS.
-
(2008)
Anticancer Res
, vol.28
, pp. 3997-4002
-
-
Wu, C.1
Jiang, J.2
Shi, L.3
-
23
-
-
77956469373
-
Anti-tumor effects of CIK combined with oxaliplatin in human oxaliplatin-resistant gastric cancer cells in vivo and in vitro
-
Zhao Q, Zhang H, Li Y, et al. Anti-tumor effects of CIK combined with oxaliplatin in human oxaliplatin-resistant gastric cancer cells in vivo and in vitro. J Exp Clin Cancer Res 2010;9:118
-
(2010)
J Exp Clin Cancer Res
, vol.9
, pp. 118
-
-
Zhao, Q.1
Zhang, H.2
Li, Y.3
-
24
-
-
79952734945
-
Cord blood-derived cytokine-induced killer cells biotherapy combined with second-line chemotherapy in thetreatment of advanced solid malignancies
-
Niu Q, Wang W, Li Y, et al. Cord blood-derived cytokine-induced killer cells biotherapy combined with second-line chemotherapy in thetreatment of advanced solid malignancies. Int Immunopharmacol 2011;11:449-56
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 449-456
-
-
Niu, Q.1
Wang, W.2
Li, Y.3
-
25
-
-
79955835802
-
Efficacy of transcatheter arterial chemoembolization combined with cytokine-induced killer cell therapy on hepatocellular carcinoma: A comparative study
-
A description of combining CIK cells with TACE in HCC patients leading to higher PFS and OS
-
Hao MZ, Lin HL, Chen Q, et al. Efficacy of transcatheter arterial chemoembolization combined with cytokine-induced killer cell therapy on hepatocellular carcinoma: a comparative study. Chin J Cancer 2010;29:172-7 A description of combining CIK cells with TACE in HCC patients leading to higher PFS and OS.
-
(2010)
Chin J Cancer
, vol.29
, pp. 172-177
-
-
Hao, M.Z.1
Lin, H.L.2
Chen, Q.3
-
26
-
-
33748068501
-
Cytokine-induced killer cell fusion to lower recurrence of hepatocellular carcinoma after transcatheter arterial chemoembolization sequentially combined with radiofrequency ablation: A randomized trial
-
Zhao M, Wu PH, Zeng YX, et al. Cytokine-induced killer cell fusion to lower recurrence of hepatocellular carcinoma after transcatheter arterial chemoembolization sequentially combined with radiofrequency ablation: a randomized trial. Zhonghua Yi Xue Za Zhi 2006;86:1823-8 (Pubitemid 44295480)
-
(2006)
National Medical Journal of China
, vol.86
, Issue.26
, pp. 1823-1828
-
-
Zhao, M.1
Wu, P.-H.2
Zeng, Y.-X.3
Xia, J.-C.4
Zhang, F.-J.5
Xian, L.-J.6
Zhang, Y.-P.7
Zhou, K.8
Fan, W.-J.9
Zhang, L.10
Gao, F.11
Zhou, Q.-M.12
-
27
-
-
70350462748
-
Therapeutic efficacy of traditional vein chemotherapy and bronchial arterial infusion combining with CIKs on III stage non-small cell lung cancer
-
Zhao G, Huang Y, Ye L, et al. Therapeutic efficacy of traditional vein chemotherapy and bronchial arterial infusion combining with CIKs on III stage non-small cell lung cancer. Zhongguo Fei Ai Za Zhi 2009;12:1000-4
-
(2009)
Zhongguo Fei Ai Za Zhi
, vol.12
, pp. 1000-1004
-
-
Zhao, G.1
Huang, Y.2
Ye, L.3
-
28
-
-
0033798785
-
A bispecific single-chain antibody directed against EpCAM/CD3 in combination with the cytokines interferon alpha and interleukin-2 efficiently retargets T and CD3+CD56+ natural-killer-like T lymphocytes to EpCAM expressing tumor cells
-
Flieger D, Kufer P, Beier I, et al. A bispecific single-chain antibody directed against EpCAM/CD3 in combination with the cytokines interferon alpha and interleukin-2 efficiently retargets T and CD3+CD56+ natural-killer-like T lymphocytes to EpCAM expressing tumor cells. Cancer Immunol Immunother 2000;49:441-8
-
(2000)
Cancer Immunol Immunother
, vol.49
, pp. 441-448
-
-
Flieger, D.1
Kufer, P.2
Beier, I.3
-
29
-
-
80053061602
-
In vitro cytotoxicity effects of cocultured DC-CIK cells combined with sorafenib against hepatocellular carcinoma
-
Zhang D, He JT. In vitro cytotoxicity effects of cocultured DC-CIK cells combined with sorafenib against hepatocellular carcinoma. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2011;27:664-7
-
(2011)
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
, vol.27
, pp. 664-667
-
-
Zhang, D.1
He, J.T.2
-
30
-
-
80051473403
-
Combining cytokine induced killer cells with vaccination in cancer immunotherapy: More than one plus one?
-
Thanendrarajan S, Nowak M, Abken H, et al. Combining cytokine induced killer cells with vaccination in cancer immunotherapy: more than one plus one? Leuk Res 2011;35:1136-42
-
(2011)
Leuk Res
, vol.35
, pp. 1136-1142
-
-
Thanendrarajan, S.1
Nowak, M.2
Abken, H.3
-
31
-
-
0035201489
-
Interactions between dendritic cells and cytokine-induced killer cells lead to an activation of both populations
-
DOI 10.1097/00002371-200111000-00007
-
Marten A, Ziske C, Schottker B, et al. Interactions between dendritic cells and cytokine-induced killer cells lead to an activation of both populations. J Immunother 2001;24:502-10 The authors provide a detailed description of the interaction between CIK cells and DCs. (Pubitemid 33104869)
-
(2001)
Journal of Immunotherapy
, vol.24
, Issue.6
, pp. 502-510
-
-
Marten, A.1
Ziske, C.2
Schottker, B.3
Renoth, S.4
Weineck, S.5
Buttgereit, P.6
Schakowski, F.7
Von Rucker, A.8
Sauerbruch, T.9
Schmidt-Wolf, I.G.H.10
-
32
-
-
36849017520
-
Efficacy of autologous renal tumor cell lysate-loaded dendritic cell vaccine in combination with cytokine-induced killer cells on advanced renal cell carcinoma - A report of ten cases
-
Wang H, Zhou FJ, Wang QJ, et al. Efficacy of autologous renal tumor cell lysate-loaded dendritic cell vaccine in combination with cytokine-induced killer cells on advanced renal cell carcinoma - a report of ten cases. Ai Zheng 2006;25:625-30
-
(2006)
Ai Zheng
, vol.25
, pp. 625-630
-
-
Wang, H.1
Zhou, F.J.2
Wang, Q.J.3
-
33
-
-
71149114221
-
Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery
-
A description of clinical application of DC-activated CIK cells in patients with NSCLC resulting in higher 2-year OS rate
-
Li H, Wang C, Yu J, et al. Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery. Cytotherapy 2009;11:1076-83 A description of clinical application of DC-activated CIK cells in patients with NSCLC resulting in higher 2-year OS rate.
-
(2009)
Cytotherapy
, vol.11
, pp. 1076-1083
-
-
Li, H.1
Wang, C.2
Yu, J.3
-
34
-
-
80054110411
-
Dendritic cells combining with cytokine-induced killer cells synergize chemotherapy in patients with late-stage non-small cell lung cancer
-
Zhong R, Teng J, Han B, et al. Dendritic cells combining with cytokine-induced killer cells synergize chemotherapy in patients with late-stage non-small cell lung cancer. Cancer Immunol Immunother 2011;60:1497-502
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1497-1502
-
-
Zhong, R.1
Teng, J.2
Han, B.3
-
35
-
-
6844240228
-
+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene
-
Finke S, Trojaneck B, Lefterova P, et al. Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+ CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene. Gene Ther 1998;5:31-9 First report on cytokine gene transfection in CIK cells resulting in higher proliferation rate and antitumour activity. (Pubitemid 28045067)
-
(1998)
Gene Therapy
, vol.5
, Issue.1
, pp. 31-39
-
-
Finke, S.1
Trojaneck, B.2
Lefterova, P.3
Csipai, M.4
Wagner, E.5
Kircheis, R.6
Neubauer, A.7
Huhn, D.8
Wittig, B.9
Schmidt-Wolf, I.G.H.10
-
36
-
-
0032698796
-
Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-1 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma
-
DOI 10.1038/sj.bjc.6690800
-
Schmidt-Wolf IG, Finke S, Trojaneck B, et al. Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma. Br J Cancer 1999;81:1009-16 The first clinical application of autologous CIK cells in patients with solid and haematological malignancies. The study revealed a considerable antitumour activity with a minimal toxicity profile. (Pubitemid 29516145)
-
(1999)
British Journal of Cancer
, vol.81
, Issue.6
, pp. 1009-1016
-
-
Schmidt-Wolf, I.G.H.1
Finke, S.2
Trojaneck, B.3
Denkena, A.4
Lefterova, P.5
Schwella, N.6
Heuft, H.-G.7
Prange, G.8
Korte, M.9
Takeya, M.10
Dorbic, T.11
Neubauer, A.12
Wittig, B.13
Huhn, D.14
-
37
-
-
77956901729
-
Enhanced cytotoxicity of IL-24 gene-modified dendritic cells co-cultured with cytokine-induced killer cells to hepatocellular carcinoma cells
-
Yu X, Xia W, Zhang T, et al. Enhanced cytotoxicity of IL-24 gene-modified dendritic cells co-cultured with cytokine-induced killer cells to hepatocellular carcinoma cells. Int J Hematol 2010;92:276-82
-
(2010)
Int J Hematol
, vol.92
, pp. 276-282
-
-
Yu, X.1
Xia, W.2
Zhang, T.3
-
38
-
-
78751628167
-
Clinical trials on CIK cells: First report of the international registry on CIK cells (IRCC)
-
First report of an IRCC for reports on clinical use of CIK cells
-
Hontscha C, Borck Y, Zhou H, et al. Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC). J Cancer Res Clin Oncol 2011;137:305-10 First report of an IRCC for reports on clinical use of CIK cells.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 305-310
-
-
Hontscha, C.1
Borck, Y.2
Zhou, H.3
|