Maternal nicotine exposure leads to decreased cardiac protein disulfide isomerase and impaired mitochondrial function in male rat offspring

Journal of Applied Toxicology

Volumn 37, Issue 12, 2017, Pages 1517-1526

  Barra, Nicole G ^a   Lisyansky, Maria ^a   Vanduzer, Taylor A ^b   Raha, Sandeep ^b   Holloway, Alison C ^b   Hardy, Daniel B ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

heart; mitochondria; perinatal nicotine exposure; protein disulfide isomerase

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CITRATE SYNTHASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; INITIATION FACTOR 2ALPHA; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NICOTINE; PROTEIN DISULFIDE ISOMERASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE DISMUTASE; TISSUE INHIBITOR OF METALLOPROTEINASE 4; MITOCHONDRIAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOPLASMIC RETICULUM STRESS; FEMALE; HEART MUSCLE CONTRACTILITY; MALE; MATERNAL EXPOSURE; MATERNAL SMOKING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; ANIMAL; CARDIAC MUSCLE; DRUG EFFECT; ENZYMOLOGY; ETIOLOGY; HEART MITOCHONDRION; METABOLISM; NEWBORN; PATHOPHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; FEMALE; MATERNAL EXPOSURE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCARDIUM; NICOTINE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEIN DISULFIDE-ISOMERASES; RATS, WISTAR;

EID: 85021845397     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3503     Document Type: Article

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