Prenatal nicotine exposure induces gender-associated left ventricular-arterial uncoupling in adult offspring

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 410-418

  Wang, Zhenhua ^a,b   Ouyang, Qiufang ^a,c   Huang, Ziyang ^a   Lin, Ling ^a   Yu, Er'Mei ^a   Ferrari, Markus W ^d  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b Quanzhou Medical College   (China)

^c FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d HSK   (Germany)

Author keywords

Gender; Nicotine; Prenatal exposure; Stiffness; Ventricular arterial coupling

Indexed keywords

NICOTINE; COLLAGEN; ELASTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL STIFFNESS; ARTERY DISEASE; ARTICLE; AUGMENTATION INDEX; BLOOD VESSEL PARAMETERS; BODY WEIGHT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; EFFECTIVE ARTERIAL ELASTANCE; ELASTIC FIBER; END SYSTOLIC ELASTANCE; FEMALE; HEART DISEASE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; MALE; MESENTERIC ARTERY; NONHUMAN; PRENATAL EXPOSURE; PRENATAL NICOTINE EXPOSURE; PULSE PRESSURE; RAT; RESISTANCE BLOOD VESSEL; SYSTOLIC BLOOD PRESSURE; VENTRICULAR ARTERIAL STIFFENING; WALL STRESS; ANIMAL; AORTA; ARTERY; DRUG EFFECTS; ELASTICITY; HEART MUSCLE CELL; HEART VENTRICLE; HEMODYNAMICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; SEX DIFFERENCE; SPRAGUE DAWLEY RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

RATTUS;

ANIMALS; AORTA; ARTERIES; COLLAGEN; ECHOCARDIOGRAPHY; ELASTICITY; ELASTIN; FEMALE; HEART VENTRICLES; HEMODYNAMICS; INJECTIONS, SUBCUTANEOUS; MALE; MYOCYTES, CARDIAC; NICOTINE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS;

EID: 84926681443     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3364     Document Type: Article

References (37)

1. Hanna ST: Nicotine effect on cardiovascular system and ion channels. J Cardiovasc Pharmacol 47: 348-358, 2006.
2. Benowitz NL and Gourlay SG: Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy. J Am Coll Cardiol 29: 1422-1431, 1997.
3. Wang Z, Huang Z, Lu G, et al: Hypoxia during pregnancy in rats leads to early morphological changes of atherosclerosis in adult offspring. Am J Physiol Heart Circ Physiol 296: H1321-H1328, 2009.
4. Gao YJ, Holloway AC, Zeng ZH, et al: Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function. Obes Res 13: 687-692, 2005.
5. Rueda-Clausen CF, Morton JS and Davidge ST: Effects of hypoxia-induced intrauterine growth restriction on cardiopulmonary structure and function during adulthood. Cardiovasc Res 81: 713-722, 2009.
6. Lawrence J, Xiao D, Xue Q, et al: Prenatal nicotine exposure increases heart susceptibility to ischemia/reperfusion injury in adult offspring. J Pharmacol Exp Ther 324: 331-341, 2008.
7. Gao YJ, Holloway AC, Su LY, et al: Effects of fetal and neonatal exposure to nicotine on blood pressure and perivascular adipose tissue function in adult life. Eur J Pharmacol 590: 264-268, 2008.
8. Xiao D, Huang X, Lawrence J, et al: Fetal and neonatal nicotine exposure differentially regulates vascular contractility in adult male and female offspring. J Pharmacol Exp Ther 320: 654-661, 2007.
9. Kim JW, Park CG, Hong SJ, et al: Acute and chronic effects of cigarette smoking on arterial stiffness. Blood Press 14: 80-85, 2005.
10. Goette A, Lendeckel U, Kuchenbecker A, et al: Cigarette smoking induces atrial fibrosis in humans via nicotine. Heart 3: 1056-1063, 2007.
11. Rajiyah G, Agarwal R, Avendano G, et al: Influence of nicotine on myocardial stiffness and fibrosis during chronic ethanol use. Alcohol Clin Exp Res 20: 985-989, 1996.
12. Fourie PR, Coetzee AR and Bolliger CT: Pulmonary artery compliance: its role in right ventricular-arterial coupling. Cardiovasc Res 26: 839-844, 1992.
13. Boychuk CR and Hayward LF: Prenatal nicotine exposure alters postnatal cardiorespiratory integration in young male but not female rats. Exp Neurol 232: 212-221, 2011.
14. Fennessy F, Casey RG and Bouchier-Hayes D: Peripheral and central arterial haemodynamic interactions are early abnormalities in young male cigarette smokers. Eur J Vasc Endovasc Surg 25: 152-158, 2003.
15. Xiao D, Xu Z, Huang X, et al: Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring. Hypertension 51: 1239-1247, 2008.
16. Sumitra M, Manikandan P, Rao KV, et al: Cardiorespiratory effects of diazepam-ketamine, xylazine-ketamine and thiopentone anesthesia in male Wistar rats - a comparative analysis. Life Sci 75: 1887-1896, 2004.
17. Jegger D, da Silva R, Jeanrenaud X, et al: Ventricular-arterial coupling in a rat model of reduced arterial compliance provoked by hypervitaminosis D and nicotine. Am J Physiol Heart Circ Physiol 291: H1942-H1951, 2006.
18. Weinberg EO, Thienelt CD, Katz SE, et al: Gender differences in molecular remodeling in pressure overload hypertrophy. J Am Coll Cardiol 34: 264-273, 1999.
19. Sahlén A, Shahgaldi K, Aagaard P, et al: Altered ventriculo-arterial coupling during exercise in athletes releasing biomarkers after endurance running. Eur J Appl Physiol 112: 4069-4079, 2012.
20. Blaudszun G and Morel DR: Relevance of the volume-axis intercept, V0, compared with the slope of end-systolic pressure-volume relationship in response to large variations in inotropy and afterload in rats. Exp Physiol 96: 1179-1195, 2011.
21. London GM, Blacher J, Pannier B, et al: Arterial wave reflections and survival in end-stage renal failure. Hypertension 38: 434-438, 2001.
22. Lartaud I, Gaillard V, Dauca M, et al: Pioglitazone protects against elastocalcinosis and improves aortic wall elasticity. Ann Pharm Fr 65: 189-194, 2007 (In French).
23. Leipner C, Grün K, Müller A, et al: Imatinib mesylate attenuates fibrosis in coxsackievirus b3-induced chronic myocarditis. Cardiovasc Res 79: 118-126, 2008.
24. Marque V, Kieffer P, Gayraud B, et al: Aortic wall mechanics and composition in a transgenic mouse model of Marfan syndrome. Arterioscler Thromb Vasc Biol 21: 1184-1189, 2001.
25. Yamamoto K, Masuyama T, Sakata Y, et al: Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart. Cardiovasc Res 55: 76-82, 2002.
26. do Carmo Pinho Franco M, Nigro D, Fortes ZB, et al: Intrauterine undernutrition - renal and vascular origin of hypertension. Cardiovasc Res 60: 228-234, 2003.
27. Xiao D, Huang X, Yang S and Zhang L: Estrogen normalizes perinatal nicotine-induced hypertensive responses in adult female rat offspring. Hypertension 61: 1246-1254, 2013.
28. Heffernan KS, Patvardhan EA, Hession M, et al: Elevated augmentation index derived from peripheral arterial tonometry is associated with abnormal ventricular-vascular coupling. Clin Physiol Funct Imaging 30: 313-317, 2010.
29. Sassalos K, Vlachopoulos C, Alexopoulos N, et al: The acute and chronic effect of cigarette smoking on the elastic properties of the ascending aorta in healthy male subjects. Hellenic J Cardiol 47: 263-268, 2006.
30. Norton GR, Tsotetsi J, Trifunovic B, et al: Myocardial stiffness is attributed to alterations in cross-linked collagen rather than total collagen or phenotypes in spontaneously hypertensive rats. Circulation 96: 1991-1998, 1997.
31. Antonini-Canterin F, Carerj S, Di Bello V, et al: Arterial stiffness and ventricular stiffness: a couple of diseases or a coupling disease? A review from the cardiologist's point of view. Eur J Echocardiogr 10: 36-43, 2009.
32. Frenneaux M and Williams L: Ventricular-arterial and ventricular-ventricular interactions and their relevance to diastolic filling. Prog Cardiovasc Dis 49: 252-262, 2007.
33. Xue Q and Zhang L: Prenatal hypoxia causes a sex-dependent increase in heart susceptibility to ischemia and reperfusion injury in adult male offspring: role of protein kinase C epsilon. J Pharmacol Exp Ther 330: 624-632, 2009.
34. Goette A: Nicotine, atrial fibrosis and atrial fibrillation: do microRNAs help to clear the smoke? Cardiovasc Res 83: 421-422, 2009.
35. Lawrence J, Chen M, Xiong F, et al: Foetal nicotine exposure causes PKCe gene repression by promoter methylation in rat hearts. Cardiovasc Res 89: 89-97, 2011.
36. Chen CH, Fetics B, Nevo E, et al: Noninvasive single-beat determination of left ventricular end-systolic elastance in humans. J Am Coll Cardiol 38: 2028-2034, 2001.
37. Kato S, Spinale FG, Tanaka R, et al: Inhibition of collagen cross-linking: effects on fibrillar collagen and ventricular diastolic function. Am J Physiol 269 (3 Pt 2): H863-H868, 1995.