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Volumn 41, Issue 8, 2016, Pages 2160-2172

The Effect of Aging on Mitochondrial Complex I and the Extent of Oxidative Stress in the Rat Brain Cortex

Author keywords

Aging cortex; Apoptosis; Complex I; Mitochondria; Oxidative stress

Indexed keywords

GRIM 19 PROTEIN; NDUFV2 PROTEIN; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); THIOL GROUP; UNCLASSIFIED DRUG;

EID: 84966643441     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-016-1931-z     Document Type: Article
Times cited : (28)

References (52)
  • 1
    • 67650134121 scopus 로고    scopus 로고
    • Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production
    • COI: 1:CAS:528:DC%2BD1MXkvFKhs7k%3D, PID: 19347761
    • Lam PY, Yin F, Hamilton RT et al (2009) Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production. Free Radic Res 43:431–439
    • (2009) Free Radic Res , vol.43 , pp. 431-439
    • Lam, P.Y.1    Yin, F.2    Hamilton, R.T.3
  • 2
    • 0038125598 scopus 로고    scopus 로고
    • Calcium signaling: dynamics, homeostasis and remodeling
    • COI: 1:CAS:528:DC%2BD3sXltVWmsr8%3D, PID: 12838335
    • Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signaling: dynamics, homeostasis and remodeling. Nat Rev Mol Cell Biol 4:517–529
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 517-529
    • Berridge, M.J.1    Bootman, M.D.2    Roderick, H.L.3
  • 3
    • 1642422773 scopus 로고    scopus 로고
    • Mitochondrial free radical production and cell signaling
    • COI: 1:CAS:528:DC%2BD2cXisFOnu7o%3D, PID: 15051313
    • Cadenas E (2004) Mitochondrial free radical production and cell signaling. Mol Aspects Med 25:17–26
    • (2004) Mol Aspects Med , vol.25 , pp. 17-26
    • Cadenas, E.1
  • 4
    • 59849101586 scopus 로고    scopus 로고
    • Function of mitochondrial Stat3 in cellular respiration
    • COI: 1:CAS:528:DC%2BD1MXhtlersbg%3D, PID: 19131594
    • Wegrzyn J, Potla R, Chwae YJ et al (2009) Function of mitochondrial Stat3 in cellular respiration. Science 323:793–797
    • (2009) Science , vol.323 , pp. 793-797
    • Wegrzyn, J.1    Potla, R.2    Chwae, Y.J.3
  • 5
    • 84864324029 scopus 로고    scopus 로고
    • GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis
    • COI: 1:CAS:528:DC%2BC38XhtlyltbrJ, PID: 22393233
    • Shulga N, Pastorino JG (2012) GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. J Cell Sci 125:2995–3003
    • (2012) J Cell Sci , vol.125 , pp. 2995-3003
    • Shulga, N.1    Pastorino, J.G.2
  • 6
    • 51249095380 scopus 로고    scopus 로고
    • Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants
    • COI: 1:CAS:528:DC%2BD1cXhtFWltbbL, PID: 18647625
    • Navarro A, Boveris A (2008) Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants. Adv Drug Deliv Rev 60:1534–1544
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1534-1544
    • Navarro, A.1    Boveris, A.2
  • 7
    • 33751574953 scopus 로고    scopus 로고
    • Bovine complex I is a complex of 45 different subunits
    • COI: 1:CAS:528:DC%2BD28XhtFSrtr3O, PID: 16950771
    • Carroll J, Fearnley IM, Skehel JM et al (2006) Bovine complex I is a complex of 45 different subunits. J Biol Chem 281:32724–32727
    • (2006) J Biol Chem , vol.281 , pp. 32724-32727
    • Carroll, J.1    Fearnley, I.M.2    Skehel, J.M.3
  • 8
    • 0036751954 scopus 로고    scopus 로고
    • Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD38XotVCiurk%3D, PID: 12392783
    • Floyd RA, Hensley K (2002) Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging 23:795–807
    • (2002) Neurobiol Aging , vol.23 , pp. 795-807
    • Floyd, R.A.1    Hensley, K.2
  • 9
    • 0035914435 scopus 로고    scopus 로고
    • GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)
    • COI: 1:CAS:528:DC%2BD3MXnvVens7w%3D, PID: 11522775
    • Fearnley IM, Carroll J, Shannon RJ et al (2001) GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I). J Biol Chem 276:38345–38348
    • (2001) J Biol Chem , vol.276 , pp. 38345-38348
    • Fearnley, I.M.1    Carroll, J.2    Shannon, R.J.3
  • 10
    • 0034721920 scopus 로고    scopus 로고
    • Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach
    • COI: 1:CAS:528:DC%2BD3cXnvVOqu7g%3D, PID: 10924506
    • Angell JE, Lindner DJ, Shapiro PS et al (2000) Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach. J Biol Chem 275:33416–33426
    • (2000) J Biol Chem , vol.275 , pp. 33416-33426
    • Angell, J.E.1    Lindner, D.J.2    Shapiro, P.S.3
  • 11
    • 33846244994 scopus 로고    scopus 로고
    • Coupling mitochondrial respiratory chain to cell death: an essential role of mitochondrial complex I in the interferon-beta and retinoic acid-induced cancer cell death
    • COI: 1:CAS:528:DC%2BD2sXkslChsQ%3D%3D, PID: 16826196
    • Huang G, Chen Y, Lu H (2007) Coupling mitochondrial respiratory chain to cell death: an essential role of mitochondrial complex I in the interferon-beta and retinoic acid-induced cancer cell death. Cell Death Differ 14:327–337
    • (2007) Cell Death Differ , vol.14 , pp. 327-337
    • Huang, G.1    Chen, Y.2    Lu, H.3
  • 12
    • 34147109143 scopus 로고    scopus 로고
    • Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits
    • COI: 1:CAS:528:DC%2BD2sXitlSrtLc%3D, PID: 17209039
    • Vogel RO, Dieteren CE, Van den Heuvel LP et al (2007) Identification of mitochondrial complex I assembly intermediates by tracing tagged NDUFS3 demonstrates the entry point of mitochondrial subunits. J Biol Chem 282:7582–7590
    • (2007) J Biol Chem , vol.282 , pp. 7582-7590
    • Vogel, R.O.1    Dieteren, C.E.2    Van den Heuvel, L.P.3
  • 13
    • 34548759101 scopus 로고    scopus 로고
    • The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis
    • COI: 1:CAS:528:DC%2BD2sXhtVKls7nM, PID: 17636012
    • Chen Y, Yuen WH, Fu J et al (2007) The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis. Mol Cell Biol 27:6420–6432
    • (2007) Mol Cell Biol , vol.27 , pp. 6420-6432
    • Chen, Y.1    Yuen, W.H.2    Fu, J.3
  • 14
    • 48249132021 scopus 로고    scopus 로고
    • GRIM-19 is essential for maintenance of mitochondrial membrane potential
    • COI: 1:CAS:528:DC%2BD1cXlslelsrs%3D, PID: 18287540
    • Lu H, Cao X (2008) GRIM-19 is essential for maintenance of mitochondrial membrane potential. Mol Biol Cell 19:1893–1902
    • (2008) Mol Biol Cell , vol.19 , pp. 1893-1902
    • Lu, H.1    Cao, X.2
  • 15
    • 34249736347 scopus 로고    scopus 로고
    • The phosphorylation pattern of bovine heart complex I subunits
    • COI: 1:CAS:528:DC%2BD2sXmtlKksrY%3D, PID: 17443843
    • Palmisano G, Sardanelli AM, Signorile A et al (2007) The phosphorylation pattern of bovine heart complex I subunits. Proteomics 7:1575–1583
    • (2007) Proteomics , vol.7 , pp. 1575-1583
    • Palmisano, G.1    Sardanelli, A.M.2    Signorile, A.3
  • 16
    • 84888110966 scopus 로고    scopus 로고
    • Assembly factors for the membrane arm of human complex I
    • COI: 1:CAS:528:DC%2BC3sXhvFCis7nP, PID: 24191001
    • Andrews B, Carroll J, Ding S et al (2013) Assembly factors for the membrane arm of human complex I. Proc Natl Acad Sci USA 110:18934–18939
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 18934-18939
    • Andrews, B.1    Carroll, J.2    Ding, S.3
  • 17
    • 33746878763 scopus 로고    scopus 로고
    • Mitochondrial complex I: structure, function and pathology
    • COI: 1:CAS:528:DC%2BD28Xnsl2ju7g%3D, PID: 16838076
    • Janssen RJ, Nijtmans LG, Van den Heuvel LP et al (2006) Mitochondrial complex I: structure, function and pathology. J Inherit Metab Dis 29:499–515
    • (2006) J Inherit Metab Dis , vol.29 , pp. 499-515
    • Janssen, R.J.1    Nijtmans, L.G.2    Van den Heuvel, L.P.3
  • 18
    • 84866880855 scopus 로고    scopus 로고
    • Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
    • COI: 1:CAS:528:DC%2BC38XhsVWmsbrF, PID: 22823520
    • Ogura M, Yamaki J, Homma MK et al (2012) Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components. Biochem J 447:281–289
    • (2012) Biochem J , vol.447 , pp. 281-289
    • Ogura, M.1    Yamaki, J.2    Homma, M.K.3
  • 19
    • 78649733457 scopus 로고    scopus 로고
    • Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
    • Nishioka K, Vilariño-Güell C, Cobb CA et al (2012) Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease. Parkinsonism Relat Disord 16:686–687
    • (2012) Parkinsonism Relat Disord , vol.16 , pp. 686-687
    • Nishioka, K.1    Vilariño-Güell, C.2    Cobb, C.A.3
  • 20
    • 84872520228 scopus 로고    scopus 로고
    • Oxidative modification of brain proteins in Alzheimer’s disease: perspective on future studies based on results of redox proteomics studies
    • Sultanaa R, Butterfield DA (2013) Oxidative modification of brain proteins in Alzheimer’s disease: perspective on future studies based on results of redox proteomics studies. J Alzheimers Dis 33:S243–S251
    • (2013) J Alzheimers Dis , vol.33 , pp. S243-S251
    • Sultanaa, R.1    Butterfield, D.A.2
  • 21
    • 84992190345 scopus 로고    scopus 로고
    • Mitochondrial complex I and III gene mRNA levels in schizophrenia and their relationship with clinical features
    • PID: 25713723
    • Akarsu S, Torun D, Bolu A et al (2014) Mitochondrial complex I and III gene mRNA levels in schizophrenia and their relationship with clinical features. J Mol Psychiatry 2:6
    • (2014) J Mol Psychiatry , vol.2 , pp. 6
    • Akarsu, S.1    Torun, D.2    Bolu, A.3
  • 22
    • 34249731463 scopus 로고    scopus 로고
    • The IFN-beta and retinoic acid-induced cell death regulator GRIM-19 is upregulated during focal cerebral ischemia
    • COI: 1:CAS:528:DC%2BD2sXls1Kisrs%3D, PID: 17523870
    • Mehrabian Z, Chandrasekaran K, Kalakonda S et al (2007) The IFN-beta and retinoic acid-induced cell death regulator GRIM-19 is upregulated during focal cerebral ischemia. J Interferon Cytokine Res 27:383–392
    • (2007) J Interferon Cytokine Res , vol.27 , pp. 383-392
    • Mehrabian, Z.1    Chandrasekaran, K.2    Kalakonda, S.3
  • 23
    • 84912527524 scopus 로고    scopus 로고
    • 2 production by isolated brain mitochondria in different respiratory states
    • COI: 1:CAS:528:DC%2BC2cXhs12nur%2FK, PID: 25287903
    • 2 production by isolated brain mitochondria in different respiratory states. Neurochem Res 39:2419–2430
    • (2014) Neurochem Res , vol.39 , pp. 2419-2430
    • Michelini, L.G.1    Benevento, C.E.2    Rossato, F.A.3
  • 24
    • 71849084134 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD1MXhsFanurnE, PID: 19733240
    • Winklhofer KF, Haass Ch (2010) Mitochondrial dysfunction in Parkinson’s disease. Biochim Biophys Acta 1802:29–44
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 29-44
    • Winklhofer, K.F.1    Haass, C.2
  • 25
    • 33746891176 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human cancer
    • COI: 1:CAS:528:DC%2BD28Xnsl2hsLs%3D, PID: 16892080
    • Chatterjee A, Mambo E, Sidransky D (2006) Mitochondrial DNA mutations in human cancer. Oncogene 25:4663–4674
    • (2006) Oncogene , vol.25 , pp. 4663-4674
    • Chatterjee, A.1    Mambo, E.2    Sidransky, D.3
  • 26
    • 35948941541 scopus 로고    scopus 로고
    • Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal
    • COI: 1:CAS:528:DC%2BD2sXhtl2rt7bK, PID: 17925093
    • Kaplan P, Tatarkova Z, Račay P et al (2007) Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal. Redox Rep 12:211–218
    • (2007) Redox Rep , vol.12 , pp. 211-218
    • Kaplan, P.1    Tatarkova, Z.2    Račay, P.3
  • 27
    • 0019791636 scopus 로고
    • A rapid method for preparing synaptosomes: comparison with alternative procedures
    • COI: 1:CAS:528:DyaL38XkvVGntw%3D%3D, PID: 7296283
    • Dodd PR, Hardy JA, Oakley AE (1981) A rapid method for preparing synaptosomes: comparison with alternative procedures. Brain Res 226:107–118
    • (1981) Brain Res , vol.226 , pp. 107-118
    • Dodd, P.R.1    Hardy, J.A.2    Oakley, A.E.3
  • 28
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • COI: 1:CAS:528:DyaG38XhsVyrsw%3D%3D, PID: 14907713
    • Lowry OH, Rosebrough NJ, Farr AL et al (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265–275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3
  • 29
    • 79959280235 scopus 로고    scopus 로고
    • Effect of aging on activities of mitochondrial electron transport chain complexes on oxidative damage rat heart
    • COI: 1:CAS:528:DC%2BC3MXotFWhs70%3D, PID: 21114360
    • Tatarkova Z, Kuka S, Račay P et al (2011) Effect of aging on activities of mitochondrial electron transport chain complexes on oxidative damage rat heart. Physiol Res 60:281–289
    • (2011) Physiol Res , vol.60 , pp. 281-289
    • Tatarkova, Z.1    Kuka, S.2    Račay, P.3
  • 30
    • 0023066977 scopus 로고
    • Spectrophotometric assay of thiols
    • COI: 1:CAS:528:DyaL1cXjsVahsg%3D%3D, PID: 3657559
    • Jocelyn PC (1987) Spectrophotometric assay of thiols. Methods Enzymol 143:44–67
    • (1987) Methods Enzymol , vol.143 , pp. 44-67
    • Jocelyn, P.C.1
  • 31
    • 0037628056 scopus 로고    scopus 로고
    • 2+-ATPase of cardiac sarcoplasmic reticulum
    • COI: 1:CAS:528:DC%2BD3sXksFWntrg%3D, PID: 12870653
    • 2+-ATPase of cardiac sarcoplasmic reticulum. Mol Cell Biochem 248:41–47
    • (2003) Mol Cell Biochem , vol.248 , pp. 41-47
    • Kaplan, P.1    Babusikova, E.2    Lehotsky, J.3
  • 32
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • COI: 1:CAS:528:DC%2BC3sXjvFOntL4%3D, PID: 23140366
    • Campisi J (2013) Aging, cellular senescence, and cancer. Annu Rev Physiol 75:685–705
    • (2013) Annu Rev Physiol , vol.75 , pp. 685-705
    • Campisi, J.1
  • 33
    • 84878864199 scopus 로고    scopus 로고
    • The hallmarks of aging
    • COI: 1:CAS:528:DC%2BC3sXptFKms78%3D, PID: 23746838
    • Lopez-Otin C, Blasco MA, Partridge L et al (2013) The hallmarks of aging. Cell 153:1194–1217
    • (2013) Cell , vol.153 , pp. 1194-1217
    • Lopez-Otin, C.1    Blasco, M.A.2    Partridge, L.3
  • 34
    • 84899813575 scopus 로고    scopus 로고
    • Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability
    • COI: 1:CAS:528:DC%2BC2cXls1Cqsr4%3D, PID: 24708184
    • Stauch KL, Purnell PR, Fox HS (2014) Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability. J Proteome Res 13:2620–2636
    • (2014) J Proteome Res , vol.13 , pp. 2620-2636
    • Stauch, K.L.1    Purnell, P.R.2    Fox, H.S.3
  • 35
    • 79955651297 scopus 로고    scopus 로고
    • Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy
    • COI: 1:CAS:528:DC%2BC3MXmsVehu7k%3D, PID: 21548921
    • Liu HY, Liao PCh, Chuang KT et al (2011) Mitochondrial targeting of human NADH dehydrogenase (ubiquinone) flavoprotein 2 (NDUFV2) and its association with early-onset hypertrophic cardiomyopathy and encephalopathy. J Biomed Sci 18:29–46
    • (2011) J Biomed Sci , vol.18 , pp. 29-46
    • Liu, H.Y.1    Liao, P.2    Chuang, K.T.3
  • 36
    • 84900447983 scopus 로고    scopus 로고
    • Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice
    • Miwa S, Jow H, Baty K et al (2014) Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice. Nat Commun 5:1–12
    • (2014) Nat Commun , vol.5 , pp. 1-12
    • Miwa, S.1    Jow, H.2    Baty, K.3
  • 37
    • 52049089147 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in rat brain with aging Involvement of complex I, reactive oxygen species and cardiolipin
    • COI: 1:CAS:528:DC%2BD1cXhtFOltbvF, PID: 18657582
    • Petrosillo G, Matera M, Casanova G et al (2008) Mitochondrial dysfunction in rat brain with aging Involvement of complex I, reactive oxygen species and cardiolipin. Neurochem Int 53:126–131
    • (2008) Neurochem Int , vol.53 , pp. 126-131
    • Petrosillo, G.1    Matera, M.2    Casanova, G.3
  • 38
    • 33947508734 scopus 로고    scopus 로고
    • Depolarization and cardiolipin depletion in aged rat brain mitochondria: relationship with oxidative stress and electron transport chain activity
    • COI: 1:CAS:528:DC%2BD2sXjsVGjtr4%3D, PID: 17331620
    • Sen T, Sen N, Jana S et al (2007) Depolarization and cardiolipin depletion in aged rat brain mitochondria: relationship with oxidative stress and electron transport chain activity. Neurochem Int 50:719–725
    • (2007) Neurochem Int , vol.50 , pp. 719-725
    • Sen, T.1    Sen, N.2    Jana, S.3
  • 39
    • 79955646829 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson’s disease
    • Navarro A, Boveris A (2010) Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson’s disease. Front Aging Neurosci 2:1–9
    • (2010) Front Aging Neurosci , vol.2 , pp. 1-9
    • Navarro, A.1    Boveris, A.2
  • 40
    • 84920266687 scopus 로고    scopus 로고
    • Metabolome and proteome profiling of complex I deficiency induced by rotenone
    • COI: 1:CAS:528:DC%2BC2cXhvVCltb%2FK, PID: 25361611
    • Gielisch I, Meierhofer D (2015) Metabolome and proteome profiling of complex I deficiency induced by rotenone. J Proteome Res 14:224–235
    • (2015) J Proteome Res , vol.14 , pp. 224-235
    • Gielisch, I.1    Meierhofer, D.2
  • 41
    • 77953357281 scopus 로고    scopus 로고
    • Ageing alters the supramolecular architecture of OxPhos complexes in rat brain cortex
    • COI: 1:CAS:528:DC%2BC3cXmslGjtLs%3D, PID: 20159033
    • Frenzel M, Rommelspacher H, Sugawa MD (2010) Ageing alters the supramolecular architecture of OxPhos complexes in rat brain cortex. Exp Gerontol 45:563–572
    • (2010) Exp Gerontol , vol.45 , pp. 563-572
    • Frenzel, M.1    Rommelspacher, H.2    Sugawa, M.D.3
  • 42
    • 0032827391 scopus 로고    scopus 로고
    • Effect of thiol modification on brain mitochondrial complex I activity
    • Balijepallia S, Annepua J, Boydb MR (1999) Effect of thiol modification on brain mitochondrial complex I activity. Neurosci Lett 272:203–206
    • (1999) Neurosci Lett , vol.272 , pp. 203-206
    • Balijepallia, S.1    Annepua, J.2    Boydb, M.R.3
  • 43
    • 84923912767 scopus 로고    scopus 로고
    • S-glutathionylation reactions in mitochondrial function and disease
    • Mailloux RJ, Willmore WG (2014) S-glutathionylation reactions in mitochondrial function and disease. Front Cell Dev Biol 2:1–17
    • (2014) Front Cell Dev Biol , vol.2 , pp. 1-17
    • Mailloux, R.J.1    Willmore, W.G.2
  • 44
    • 84930578085 scopus 로고    scopus 로고
    • Neurochemical aspects of oxidative and nitrosative stress. In: Inflammation and oxidative stress in neurological disorders. Springer International Publishing, pp. 175–206
    • Farooqui AA (2014) Neurochemical aspects of oxidative and nitrosative stress. In: Inflammation and oxidative stress in neurological disorders. Springer International Publishing, pp. 175–206. doi:10.1007/978-3-319-04111-7_6
    • (2014) doi:10.1007/978-3-319-04111-7_6
    • Farooqui, A.A.1
  • 45
    • 79953677172 scopus 로고    scopus 로고
    • Apoptosis and aging: increased resistance to apoptosis enhances the aging process
    • COI: 1:CAS:528:DC%2BC3MXit1Kls7o%3D, PID: 21116678
    • Salminen A, Ojala J, Kaarniranta K (2011) Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol Life Sci 68:1021–1031
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1021-1031
    • Salminen, A.1    Ojala, J.2    Kaarniranta, K.3
  • 46
    • 84862887624 scopus 로고    scopus 로고
    • Ischemia-induced inhibition of mitochondrial complex I in rat brain: effect of permeabilization method and electron acceptor
    • COI: 1:CAS:528:DC%2BC38XisV2jsw%3D%3D, PID: 22219133
    • Chomova M, Tatarkova Z, Dobrota D et al (2012) Ischemia-induced inhibition of mitochondrial complex I in rat brain: effect of permeabilization method and electron acceptor. Neurochem Res 37:965–976
    • (2012) Neurochem Res , vol.37 , pp. 965-976
    • Chomova, M.1    Tatarkova, Z.2    Dobrota, D.3
  • 47
    • 84874066734 scopus 로고    scopus 로고
    • The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain
    • COI: 1:CAS:528:DC%2BC3sXis1ait74%3D, PID: 23271731
    • Tammineni P, Anugula Ch, Mohammed F et al (2013) The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain. J Biol Chem 288:4723–4732
    • (2013) J Biol Chem , vol.288 , pp. 4723-4732
    • Tammineni, P.1    Anugula, C.2    Mohammed, F.3
  • 48
    • 79960186102 scopus 로고    scopus 로고
    • GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers
    • Zhou Y, Wei Y, Zhu J et al (2011) GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers. PLoS ONE 6:1–12
    • (2011) PLoS ONE , vol.6 , pp. 1-12
    • Zhou, Y.1    Wei, Y.2    Zhu, J.3
  • 49
    • 79955472010 scopus 로고    scopus 로고
    • Gene associated with retinoid-interferon-induced mortality-19 suppresses growth of lung adenocarcinoma tumor in vitro and in vivo
    • PID: 21040996
    • Wang T, Yan XB, Zhao JJ et al (2011) Gene associated with retinoid-interferon-induced mortality-19 suppresses growth of lung adenocarcinoma tumor in vitro and in vivo. Lung Cancer 72:287–293
    • (2011) Lung Cancer , vol.72 , pp. 287-293
    • Wang, T.1    Yan, X.B.2    Zhao, J.J.3
  • 50
    • 80051943914 scopus 로고    scopus 로고
    • Mitochondrial targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species
    • COI: 1:CAS:528:DC%2BC3MXhtVCns7bP, PID: 21715323
    • Szczepanek K, Chen Q, Derecka M et al (2011) Mitochondrial targeted Signal transducer and activator of transcription 3 (STAT3) protects against ischemia-induced changes in the electron transport chain and the generation of reactive oxygen species. J Biol Chem 286:29610–29620
    • (2011) J Biol Chem , vol.286 , pp. 29610-29620
    • Szczepanek, K.1    Chen, Q.2    Derecka, M.3
  • 51
    • 84898921083 scopus 로고    scopus 로고
    • STAT3 target genes relevant to human cancers
    • COI: 1:CAS:528:DC%2BC2cXhs1Crs7fN, PID: 24743777
    • Carpenter R, Lo HW (2014) STAT3 target genes relevant to human cancers. Cancers 6:897–925
    • (2014) Cancers , vol.6 , pp. 897-925
    • Carpenter, R.1    Lo, H.W.2
  • 52
    • 77952554792 scopus 로고    scopus 로고
    • The role of p53 in apoptosis
    • PID: 20193641
    • Amaral JD, Xavier JM, Steer CJ et al (2010) The role of p53 in apoptosis. Discov Med 9:145–152
    • (2010) Discov Med , vol.9 , pp. 145-152
    • Amaral, J.D.1    Xavier, J.M.2    Steer, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.