Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation

Cell Host and Microbe

Volumn 22, Issue 1, 2017, Pages 25-37.e6

  Wlodarska, Marta ^a,b   Luo, Chengwei ^a,c   Kolde, Raivo ^c   d'Hennezel, Eva ^b   Annand, John W ^b   Heim, Cortney E ^a,b   Krastel, Philipp ^d   Schmitt, Esther K ^d   Omar, Abdifatah S ^a   Creasey, Elizabeth A ^c   Garner, Ashley L ^a   Mohammadi, Sina ^b   O'Connell, Daniel J ^a   Abubucker, Sahar ^b   Arthur, Timothy D ^a   Franzosa, Eric A ^a,e   Huttenhower, Curtis ^a,e   Murphy, Leon O ^b   Haiser, Henry J ^b   Vlamakis, Hera ^a   Porter, Jeffrey A ^b   Xavier, Ramnik J ^a,c   more..

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

indoleacrylic acid; indolepropionic acid; Muc2; mucus; organoid; Peptostreptococcus

Indexed keywords

ACRYLIC ACID; INDOLE DERIVATIVE; INDOLEACRYLIC ACID; MONOSACCHARIDE; MUCIN; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; CYTOKINE; MUCIN 2;

ANIMAL CELL; ARTICLE; CLOSTRIDIALES; CYTOKINE PRODUCTION; FECES ANALYSIS; GENE CLUSTER; HUMAN; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; INTESTINE; INTESTINE EPITHELIUM; INTESTINE FLORA; MEMBRANE PERMEABILITY; METAGENOMICS; MOUSE; NONHUMAN; PEPTOSTREPTOCOCCUS; PEPTOSTREPTOCOCCUS RUSSELLII; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TRYPTOPHAN METABOLISM; ANIMAL; BACTERIUM; BACTEROIDES; CLASSIFICATION; COLON; DYSBIOSIS; GENETICS; INFLAMMATORY BOWEL DISEASE; INJURIES; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; ORGANOID; PATHOLOGY; SECRETION (PROCESS); SYMBIOSIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BACTERIA; BACTEROIDES; CLOSTRIDIALES; COLON; CYTOKINES; DYSBIOSIS; HUMANS; INDOLES; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; INTESTINES; MICE; MUCIN-2; MUCINS; ORGANOIDS; PEPTOSTREPTOCOCCUS; SYMBIOSIS;

EID: 85021811792     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.06.007     Document Type: Article

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