CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Nature Medicine

Volumn 22, Issue 6, 2016, Pages 598-605

  Lamas, Bruno ^a,b,c,d,e,f   Richard, Mathias L ^e,f   Leducq, Valentin ^a,b,c,d,f   Pham, Hang Phuong ^g   Michel, Marie Laure ^e,f   Da Costa, Gregory ^e,f   Bridonneau, Chantal ^e,f   Jegou, Sarah ^a,b,c,d,f   Hoffmann, Thomas W ^e,f   Natividad, Jane M ^e,f   Brot, Loic ^a,b,c,d,f   Taleb, Soraya ^h,i   Couturier Maillard, Aurélie ^j   Nion Larmurier, Isabelle ^k   Merabtene, Fatiha ^l   Seksik, Philippe ^k,p   Bourrier, Anne ^k,p   Cosnes, Jacques ^k   Ryffel, Bernhard ^j,m   Beaugerie, Laurent ^k   Launay, Jean Marie ⁿ   Langella, Philippe ^e,f   Xavier, Ramnik J ^o,q   Sokol, Harry ^{a,b,c,d,e,f,k}   more..

^a SORBONNE UNIVERSITÉ   (France)

^b INSERM   (France)

^c CNRS   (France)

^d Section of Radiology   (France)

^e UNIVERSITÉ PARIS SACLAY   (France)

^f Inflammation Immunopathology Biotherapy Department (DHU i2B)   (France)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^h PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

ⁱ UNIVERSITÉ PARIS DESCARTES   (France)

^j Laboratoire d'Immunologie et Embryologie Moleculaires Orleans   (France)

^k ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^l CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^m UNIVERSITY OF CAPE TOWN   (South Africa)

ⁿ HÔPITAL LARIBOISIÈRE   (France)

^o BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^p MASSACHUSETTS GENERAL HOSPITAL   (United States)

^q MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CASPASE RECRUITMENT DOMAIN FAMILY MEMBER 9; INDOLEACETIC ACID; INTERLEUKIN 22; KYNURENINE; PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG; CARD9 PROTEIN, MOUSE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CYTOKINE; DEXTRAN SULFATE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; RNA 16S;

ALLELE; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; COLITIS; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; EPITHELIUM CELL; GENE; GENE FUNCTION; HOST CELL; IMMUNE RESPONSE; IN VIVO STUDY; INFLAMMATORY BOWEL DISEASE; INOCULATION; INTESTINE FLORA; LACTOBACILLUS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; ADOLESCENT; ADULT; ANIMAL; CHEMICALLY INDUCED; COLON; FECAL MICROBIOTA TRANSPLANTATION; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLITIS; COLON; CYTOKINES; DEXTRAN SULFATE; FECAL MICROBIOTA TRANSPLANTATION; FEMALE; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION PROFILING; HUMANS; INFLAMMATORY BOWEL DISEASES; INTERLEUKINS; LACTOBACILLUS; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S; TRYPTOPHAN; YOUNG ADULT;

EID: 84966526506     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4102     Document Type: Article

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