-
1
-
-
0034658658
-
Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice
-
Santini, S.M., Lapenta, C., Logozzi, M., Parlato, S., Spada, M., Di Pucchio, T., et al. Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J. Exp. Med. 191 (2000), 1777–1788.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1777-1788
-
-
Santini, S.M.1
Lapenta, C.2
Logozzi, M.3
Parlato, S.4
Spada, M.5
Di Pucchio, T.6
-
2
-
-
0038515256
-
Gene expression profiling and functional activity of human dendritic cells induced with IFN-alpha-2b: implications for cancer immunotherapy
-
Moschella, F., Bisikirska, B., Maffei, A., Papadopoulos, K.P., Skerrett, D., Liu, Z., et al. Gene expression profiling and functional activity of human dendritic cells induced with IFN-alpha-2b: implications for cancer immunotherapy. Clin. Cancer Res. 9 (2003), 2022–2031.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2022-2031
-
-
Moschella, F.1
Bisikirska, B.2
Maffei, A.3
Papadopoulos, K.P.4
Skerrett, D.5
Liu, Z.6
-
3
-
-
79952515648
-
Regulation of effector and memory T-cell functions by type I interferon
-
Huber, J.P., Farrar, J.D., Regulation of effector and memory T-cell functions by type I interferon. Immunology 132 (2011), 466–474, 10.1111/j.1365-2567.2011.03412.x.
-
(2011)
Immunology
, vol.132
, pp. 466-474
-
-
Huber, J.P.1
Farrar, J.D.2
-
4
-
-
84926451174
-
NK cells and interferons
-
Paolini, R., Bernardini, G., Molfetta, R., Santoni, A., NK cells and interferons. Cytokine Growth Factor Rev. 26 (2015), 113–120, 10.1016/j.cytogfr.2014.11.003.
-
(2015)
Cytokine Growth Factor Rev.
, vol.26
, pp. 113-120
-
-
Paolini, R.1
Bernardini, G.2
Molfetta, R.3
Santoni, A.4
-
5
-
-
77957745555
-
Type I interferon: friend or foe?
-
Trinchieri, G., Type I interferon: friend or foe?. J. Exp Med. 207 (2010), 2053–2063, 10.1084/jem.20101664.
-
(2010)
J. Exp Med.
, vol.207
, pp. 2053-2063
-
-
Trinchieri, G.1
-
6
-
-
84926513317
-
Twenty-five years of type I interferon-based treatment: a critical analysis of its therapeutic use
-
Antonelli, G., Scagnolari, C., Moschella, F., Proietti, E., Twenty-five years of type I interferon-based treatment: a critical analysis of its therapeutic use. Cytokine Growth Factor Rev. 26 (2015), 121–131, 10.1016/j.cytogfr.2014.12.006.
-
(2015)
Cytokine Growth Factor Rev.
, vol.26
, pp. 121-131
-
-
Antonelli, G.1
Scagnolari, C.2
Moschella, F.3
Proietti, E.4
-
7
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
Platanias, L.C., Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5 (2005), 375–386, 10.1038/nri1604.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 375-386
-
-
Platanias, L.C.1
-
8
-
-
84862169105
-
Interferon-alpha as antiviral and antitumor vaccine adjuvants: mechanisms of action and response signature
-
Arico, E., Belardelli, F., Interferon-alpha as antiviral and antitumor vaccine adjuvants: mechanisms of action and response signature. J. Interferon Cytokine Res. 32 (2012), 235–247, 10.1089/jir.2011.0077.
-
(2012)
J. Interferon Cytokine Res.
, vol.32
, pp. 235-247
-
-
Arico, E.1
Belardelli, F.2
-
9
-
-
84926476403
-
Role of type I interferon in inducing a protective immune response: perspectives for clinical applications
-
Rizza, P., Moretti, F., Capone, I., Belardelli, F., Role of type I interferon in inducing a protective immune response: perspectives for clinical applications. Cytokine Growth Factor Rev. 26 (2015), 195–201, 10.1016/j.cytogfr.2014.10.002.
-
(2015)
Cytokine Growth Factor Rev.
, vol.26
, pp. 195-201
-
-
Rizza, P.1
Moretti, F.2
Capone, I.3
Belardelli, F.4
-
10
-
-
84933277745
-
Type I interferons in anticancer immunity
-
Zitvogel, L., Galluzzi, L., Kepp, O., Smyth, M.J., Kroemer, G., Type I interferons in anticancer immunity. Nat. Rev. Immunol. 15 (2015), 405–414, 10.1038/nri3845.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 405-414
-
-
Zitvogel, L.1
Galluzzi, L.2
Kepp, O.3
Smyth, M.J.4
Kroemer, G.5
-
11
-
-
0020402958
-
Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. I
-
Belardelli, F., Gresser, I., Maury, C., Maunoury, M.T., Antitumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. I. Int. J. Cancer 30 (1982), 813–820.
-
(1982)
Int. J. Cancer
, vol.30
, pp. 813-820
-
-
Belardelli, F.1
Gresser, I.2
Maury, C.3
Maunoury, M.T.4
-
12
-
-
0025005051
-
Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend erythroleukemia cells. VIII. Role of the immune system in the inhibition of visceral metastases
-
Gresser, I., Maury, C., Carnaud, C., De Maeyer, E., Maunoury, M.T., Belardelli, F., Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend erythroleukemia cells. VIII. Role of the immune system in the inhibition of visceral metastases. Int. J. Cancer 46 (1990), 468–474.
-
(1990)
Int. J. Cancer
, vol.46
, pp. 468-474
-
-
Gresser, I.1
Maury, C.2
Carnaud, C.3
De Maeyer, E.4
Maunoury, M.T.5
Belardelli, F.6
-
13
-
-
0030221837
-
The neglected role of type I interferon in the T-cell response: implications for its clinical use
-
Belardelli, F., Gresser, I., The neglected role of type I interferon in the T-cell response: implications for its clinical use. Immunol. Today 17 (1996), 369–372, 10.1016/0167-5699(96)10027-X.
-
(1996)
Immunol. Today
, vol.17
, pp. 369-372
-
-
Belardelli, F.1
Gresser, I.2
-
14
-
-
0033941331
-
Gene therapy of cancer with interferon: lessons from tumor models and perspectives for clinical applications
-
Ferrantini, M., Belardelli, F., Gene therapy of cancer with interferon: lessons from tumor models and perspectives for clinical applications. Semin. Cancer Biol. 10 (2000), 145–157, 10.1006/scbi.2000.0333.
-
(2000)
Semin. Cancer Biol.
, vol.10
, pp. 145-157
-
-
Ferrantini, M.1
Belardelli, F.2
-
15
-
-
84855472349
-
In vivo delivery of interferon-alpha gene enhances tumor immunity and suppresses immunotolerance in reconstituted lymphopenic hosts
-
Narumi, K., Udagawa, T., Kondoh, A., Kobayashi, A., Hara, H., Ikarashi, Y., et al. In vivo delivery of interferon-alpha gene enhances tumor immunity and suppresses immunotolerance in reconstituted lymphopenic hosts. Gene Ther. 19 (2012), 34–48, 10.1038/gt.2011.73.
-
(2012)
Gene Ther.
, vol.19
, pp. 34-48
-
-
Narumi, K.1
Udagawa, T.2
Kondoh, A.3
Kobayashi, A.4
Hara, H.5
Ikarashi, Y.6
-
16
-
-
84892497056
-
Genetic engineering of hematopoiesis for targeted IFN-alpha delivery inhibits breast cancer progression
-
(217ra3)
-
Escobar, G., Moi, D., Ranghetti, A., Ozkal-Baydin, P., Squadrito, M.L., Kajaste-Rudnitski, A., et al. Genetic engineering of hematopoiesis for targeted IFN-alpha delivery inhibits breast cancer progression. Sci. Transl. Med., 6, 2014, 10.1126/scitranslmed.3006353 (217ra3).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Escobar, G.1
Moi, D.2
Ranghetti, A.3
Ozkal-Baydin, P.4
Squadrito, M.L.5
Kajaste-Rudnitski, A.6
-
17
-
-
0021070204
-
Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors
-
Gresser, I., Belardelli, F., Maury, C., Maunoury, M.T., Tovey, M.G., Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors. J. Exp. Med. 158 (1983), 2095–2107.
-
(1983)
J. Exp. Med.
, vol.158
, pp. 2095-2107
-
-
Gresser, I.1
Belardelli, F.2
Maury, C.3
Maunoury, M.T.4
Tovey, M.G.5
-
18
-
-
0036264330
-
Enhanced tumor development in mice lacking a functional type I interferon receptor
-
Picaud, S., Bardot, B., De Maeyer, E., Seif, I., Enhanced tumor development in mice lacking a functional type I interferon receptor. J. Interferon Cytokine Res. 22 (2002), 457–462, 10.1089/10799900252952244.
-
(2002)
J. Interferon Cytokine Res.
, vol.22
, pp. 457-462
-
-
Picaud, S.1
Bardot, B.2
De Maeyer, E.3
Seif, I.4
-
19
-
-
33750321707
-
Interferons, immunity and cancer immunoediting
-
Dunn, G.P., Koebel, C.M., Schreiber, R.D., Interferons, immunity and cancer immunoediting. Nat. Rev. Immunol. 6 (2006), 836–848.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 836-848
-
-
Dunn, G.P.1
Koebel, C.M.2
Schreiber, R.D.3
-
20
-
-
80355147292
-
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
-
Diamond, M.S., Kinder, M., Matsushita, H., Mashayekhi, M., Dunn, G.P., Archambault, J.M., et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J. Exp. Med. 208 (2011), 1989–2003, 10.1084/jem.20101158.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1989-2003
-
-
Diamond, M.S.1
Kinder, M.2
Matsushita, H.3
Mashayekhi, M.4
Dunn, G.P.5
Archambault, J.M.6
-
21
-
-
21744459533
-
Type I interferon-associated recruitment of cytotoxic lymphocytes: a common mechanism in regressive melanocytic lesions
-
Wenzel, J., Bekisch, B., Uerlich, M., Haller, O., Bieber, T., Tuting, T., Type I interferon-associated recruitment of cytotoxic lymphocytes: a common mechanism in regressive melanocytic lesions. Am. J. Clin. Pathol. 124 (2005), 37–48, 10.1309/4EJ9KL7CGDENVVLE.
-
(2005)
Am. J. Clin. Pathol.
, vol.124
, pp. 37-48
-
-
Wenzel, J.1
Bekisch, B.2
Uerlich, M.3
Haller, O.4
Bieber, T.5
Tuting, T.6
-
22
-
-
84864654660
-
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape
-
Bidwell, B.N., Slaney, C.Y., Withana, N.P., Forster, S., Cao, Y., Loi, S., et al. Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape. Nat. Med. 18 (2012), 1224–1231, 10.1038/nm.2830.
-
(2012)
Nat. Med.
, vol.18
, pp. 1224-1231
-
-
Bidwell, B.N.1
Slaney, C.Y.2
Withana, N.P.3
Forster, S.4
Cao, Y.5
Loi, S.6
-
23
-
-
84947773168
-
Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors
-
Derer, A., Frey, B., Fietkau, R., Gaipl, U.S., Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors. Cancer Immunol. Immunother. 65 (2016), 779–786, 10.1007/s00262-015-1771-8.
-
(2016)
Cancer Immunol. Immunother.
, vol.65
, pp. 779-786
-
-
Derer, A.1
Frey, B.2
Fietkau, R.3
Gaipl, U.S.4
-
24
-
-
84954420588
-
From DNA damage to nucleic acid sensing: a strategy to enhance radiation therapy
-
Deng, L., Liang, H., Fu, S., Weichselbaum, R.R., Fu, Y.X., From DNA damage to nucleic acid sensing: a strategy to enhance radiation therapy. Clin. Cancer Res. 22 (2016), 20–25, 10.1158/1078-0432.CCR-14-3110.
-
(2016)
Clin. Cancer Res.
, vol.22
, pp. 20-25
-
-
Deng, L.1
Liang, H.2
Fu, S.3
Weichselbaum, R.R.4
Fu, Y.X.5
-
25
-
-
0013071190
-
Whole body irradiation; radiobiology or medicine?
-
Mole, R.H., Whole body irradiation; radiobiology or medicine?. Br J. Radiol. 26 (1953), 234–241, 10.1259/0007-1285-26-305-234.
-
(1953)
Br J. Radiol.
, vol.26
, pp. 234-241
-
-
Mole, R.H.1
-
26
-
-
1242315588
-
Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated
-
Demaria, S., Ng, B., Devitt, M.L., Babb, J.S., Kawashima, N., Liebes, L., et al. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int. J. Radiat. Oncol. Biol. Phys. 58 (2004), 862–870, 10.1016/j.ijrobp.2003.09.012.
-
(2004)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.58
, pp. 862-870
-
-
Demaria, S.1
Ng, B.2
Devitt, M.L.3
Babb, J.S.4
Kawashima, N.5
Liebes, L.6
-
27
-
-
84857815877
-
Immunologic correlates of the abscopal effect in a patient with melanoma
-
Postow, M.A., Callahan, M.K., Barker, C.A., Yamada, Y., Yuan, J., Kitano, S., et al. Immunologic correlates of the abscopal effect in a patient with melanoma. N. Engl. J. Med. 366 (2012), 925–931, 10.1056/NEJMoa1112824.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 925-931
-
-
Postow, M.A.1
Callahan, M.K.2
Barker, C.A.3
Yamada, Y.4
Yuan, J.5
Kitano, S.6
-
28
-
-
0015407620
-
In vivo and in vitro studies of the influence of the immune status of C3Hf-Bu mice on the effectiveness of local irradiation of a methylcholanthrene-induced fibrosarcoma
-
Jurin, M., Suit, H.D., In vivo and in vitro studies of the influence of the immune status of C3Hf-Bu mice on the effectiveness of local irradiation of a methylcholanthrene-induced fibrosarcoma. Cancer Res. 32 (1972), 2201–2211.
-
(1972)
Cancer Res.
, vol.32
, pp. 2201-2211
-
-
Jurin, M.1
Suit, H.D.2
-
29
-
-
3843124144
-
A sense of danger from radiation
-
McBride, W.H., Chiang, C.S., Olson, J.L., Wang, C.C., Hong, J.H., Pajonk, F., et al. A sense of danger from radiation. Radiat. Res. 162 (2004), 1–19.
-
(2004)
Radiat. Res.
, vol.162
, pp. 1-19
-
-
McBride, W.H.1
Chiang, C.S.2
Olson, J.L.3
Wang, C.C.4
Hong, J.H.5
Pajonk, F.6
-
30
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono, H., Rock, K.L., How dying cells alert the immune system to danger. Nat. Rev. Immunol. 8 (2008), 279–289, 10.1038/nri2215.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
31
-
-
0024815235
-
Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation
-
Hallahan, D.E., Spriggs, D.R., Beckett, M.A., Kufe, D.W., Weichselbaum, R.R., Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation. Proc. Natl. Acad. Sci. U S A 86 (1989), 10104–10107.
-
(1989)
Proc. Natl. Acad. Sci. U S A
, vol.86
, pp. 10104-10107
-
-
Hallahan, D.E.1
Spriggs, D.R.2
Beckett, M.A.3
Kufe, D.W.4
Weichselbaum, R.R.5
-
32
-
-
0028509456
-
Ionizing radiation-induced IL-1 alpha, IL-6 and GM-CSF production by human lung cancer cells
-
Zhang, J.S., Nakatsugawa, S., Niwa, O., Ju, G.Z., Liu, S.Z., Ionizing radiation-induced IL-1 alpha, IL-6 and GM-CSF production by human lung cancer cells. Chin. Med. J. (Engl.) 107 (1994), 653–657.
-
(1994)
Chin. Med. J. (Engl.)
, vol.107
, pp. 653-657
-
-
Zhang, J.S.1
Nakatsugawa, S.2
Niwa, O.3
Ju, G.Z.4
Liu, S.Z.5
-
33
-
-
0027511929
-
Induction of the expression of the interleukin-1 beta gene in mouse spleen by ionizing radiation
-
Ishihara, H., Tsuneoka, K., Dimchev, A.B., Shikita, M., Induction of the expression of the interleukin-1 beta gene in mouse spleen by ionizing radiation. Radiat. Res. 133 (1993), 321–326.
-
(1993)
Radiat. Res.
, vol.133
, pp. 321-326
-
-
Ishihara, H.1
Tsuneoka, K.2
Dimchev, A.B.3
Shikita, M.4
-
34
-
-
79953295544
-
The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity
-
Burnette, B.C., Liang, H., Lee, Y., Chlewicki, L., Khodarev, N.N., Weichselbaum, R.R., et al. The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res. 71 (2011), 2488–2496, 10.1158/0008-5472.CAN-10-2820.
-
(2011)
Cancer Res.
, vol.71
, pp. 2488-2496
-
-
Burnette, B.C.1
Liang, H.2
Lee, Y.3
Chlewicki, L.4
Khodarev, N.N.5
Weichselbaum, R.R.6
-
35
-
-
20444406500
-
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
-
Lugade, A.A., Moran, J.P., Gerber, S.A., Rose, R.C., Frelinger, J.G., Lord, E.M., Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. J.Immunol 174 (2005), 7516–7523.
-
(2005)
J.Immunol
, vol.174
, pp. 7516-7523
-
-
Lugade, A.A.1
Moran, J.P.2
Gerber, S.A.3
Rose, R.C.4
Frelinger, J.G.5
Lord, E.M.6
-
36
-
-
84912128872
-
STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors
-
Deng, L., Liang, H., Xu, M., Yang, X., Burnette, B., Arina, A., et al. STING-dependent cytosolic DNA sensing promotes radiation-induced type I interferon-dependent antitumor immunity in immunogenic tumors. Immunity 41 (2014), 843–852, 10.1016/j.immuni.2014.10.019.
-
(2014)
Immunity
, vol.41
, pp. 843-852
-
-
Deng, L.1
Liang, H.2
Xu, M.3
Yang, X.4
Burnette, B.5
Arina, A.6
-
37
-
-
84991790808
-
Abscopal effects of radiotherapy are enhanced by combined immunostimulatory mAbs and are dependent on CD8 T cells and crosspriming
-
Rodriguez-Ruiz, M.E., Rodriguez, I., Garasa, S., Barbes, B., Solorzano, J.L., Perez-Gracia, J.L., et al. Abscopal effects of radiotherapy are enhanced by combined immunostimulatory mAbs and are dependent on CD8 T cells and crosspriming. Cancer Res. 76 (2016), 5994–6005, 10.1158/0008-5472.CAN-16-0549.
-
(2016)
Cancer Res.
, vol.76
, pp. 5994-6005
-
-
Rodriguez-Ruiz, M.E.1
Rodriguez, I.2
Garasa, S.3
Barbes, B.4
Solorzano, J.L.5
Perez-Gracia, J.L.6
-
38
-
-
84894489353
-
Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells
-
Lim, J.Y., Gerber, S.A., Murphy, S.P., Lord, E.M., Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells. Cancer Immunol. Immunother. 63 (2014), 259–271, 10.1007/s00262-013-1506-7.
-
(2014)
Cancer Immunol. Immunother.
, vol.63
, pp. 259-271
-
-
Lim, J.Y.1
Gerber, S.A.2
Murphy, S.P.3
Lord, E.M.4
-
39
-
-
84896958063
-
Innate immune sensing and signaling of cytosolic nucleic acids
-
Wu, J., Chen, Z.J., Innate immune sensing and signaling of cytosolic nucleic acids. Annu. Rev. Immunol. 32 (2014), 461–488, 10.1146/annurev-immunol-032713-120156.
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 461-488
-
-
Wu, J.1
Chen, Z.J.2
-
40
-
-
84922484139
-
DNA damage and innate immunity: links and trade-offs
-
Chatzinikolaou, G., Karakasilioti, I., Garinis, G.A., DNA damage and innate immunity: links and trade-offs. Trends Immunol. 35 (2014), 429–435, 10.1016/j.it.2014.06.003.
-
(2014)
Trends Immunol.
, vol.35
, pp. 429-435
-
-
Chatzinikolaou, G.1
Karakasilioti, I.2
Garinis, G.A.3
-
41
-
-
33751419716
-
Surviving the breakup: the DNA damage checkpoint
-
Harrison, J.C., Haber, J.E., Surviving the breakup: the DNA damage checkpoint. Annu. Rev. Genet. 40 (2006), 209–235, 10.1146/annurev.genet.40.051206.105231.
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
42
-
-
84916894965
-
STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells
-
Klarquist, J., Hennies, C.M., Lehn, M.A., Reboulet, R.A., Feau, S., Janssen, E.M., STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells. J. Immunol. 193 (2014), 6124–6134, 10.4049/jimmunol.1401869.
-
(2014)
J. Immunol.
, vol.193
, pp. 6124-6134
-
-
Klarquist, J.1
Hennies, C.M.2
Lehn, M.A.3
Reboulet, R.A.4
Feau, S.5
Janssen, E.M.6
-
43
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa, H., Ma, Z., Barber, G.N., STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461 (2009), 788–792, 10.1038/nature08476.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
44
-
-
84869794842
-
STING manifests self DNA-dependent inflammatory disease
-
Ahn, J., Gutman, D., Saijo, S., Barber, G.N., STING manifests self DNA-dependent inflammatory disease. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 19386–19391, 10.1073/pnas.1215006109.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 19386-19391
-
-
Ahn, J.1
Gutman, D.2
Saijo, S.3
Barber, G.N.4
-
45
-
-
84947217032
-
Molecular pathways targeting the stimulator of interferon genes (STING) in the immunotherapy of cancer
-
Corrales, L., Gajewski, T.F., Molecular pathways targeting the stimulator of interferon genes (STING) in the immunotherapy of cancer. Clin. Cancer Res. 21 (2015), 4774–4779, 10.1158/1078-0432.CCR-15-1362.
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 4774-4779
-
-
Corrales, L.1
Gajewski, T.F.2
-
46
-
-
81355146737
-
Cytosolic DNA sensors regulating type I interferon induction
-
Keating, S.E., Baran, M., Bowie, A.G., Cytosolic DNA sensors regulating type I interferon induction. Trends Immunol. 32 (2011), 574–581, 10.1016/j.it.2011.08.004.
-
(2011)
Trends Immunol.
, vol.32
, pp. 574-581
-
-
Keating, S.E.1
Baran, M.2
Bowie, A.G.3
-
47
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339 (2013), 786–791, 10.1126/science.1232458.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
48
-
-
84922986861
-
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity
-
Hartlova, A., Erttmann, S.F., Raffi, F.A., Schmalz, A.M., Resch, U., Anugula, S., et al. DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity. Immunity 42 (2015), 332–343, 10.1016/j.immuni.2015.01.012.
-
(2015)
Immunity
, vol.42
, pp. 332-343
-
-
Hartlova, A.1
Erttmann, S.F.2
Raffi, F.A.3
Schmalz, A.M.4
Resch, U.5
Anugula, S.6
-
49
-
-
84966891722
-
Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs
-
Ranoa, D.R., Parekh, A.D., Pitroda, S.P., Huang, X., Darga, T., Wong, A.C., et al. Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget 7 (2016), 26496–26515, 10.18632/oncotarget.8420.
-
(2016)
Oncotarget
, vol.7
, pp. 26496-26515
-
-
Ranoa, D.R.1
Parekh, A.D.2
Pitroda, S.P.3
Huang, X.4
Darga, T.5
Wong, A.C.6
-
50
-
-
81455154853
-
The DNA damage response induces IFN
-
Brzostek-Racine, S., Gordon, C., Van Scoy, S., Reich, N.C., The DNA damage response induces IFN. J. Immunol. 187 (2011), 5336–5345, 10.4049/jimmunol.1100040.
-
(2011)
J. Immunol.
, vol.187
, pp. 5336-5345
-
-
Brzostek-Racine, S.1
Gordon, C.2
Van Scoy, S.3
Reich, N.C.4
-
51
-
-
84928205707
-
Genome-derived cytosolic DNA mediates type I interferon-dependent rejection of B cell lymphoma cells
-
Shen, Y.J., Le Bert, N., Chitre, A.A., Koo, C.X., Nga, X.H., Ho, S.S., et al. Genome-derived cytosolic DNA mediates type I interferon-dependent rejection of B cell lymphoma cells. Cell Rep. 11 (2015), 460–473, 10.1016/j.celrep.2015.03.041.
-
(2015)
Cell Rep.
, vol.11
, pp. 460-473
-
-
Shen, Y.J.1
Le Bert, N.2
Chitre, A.A.3
Koo, C.X.4
Nga, X.H.5
Ho, S.S.6
-
52
-
-
85019113636
-
Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion
-
Luthra, P., Aguirre, S., Yen, B.C., Pietzsch, C.A., Sanchez-Aparicio, M.T., Tigabu, B., et al. Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion. MBio, 8, 2017, 10.1128/mBio.00368-17.
-
(2017)
MBio
, vol.8
-
-
Luthra, P.1
Aguirre, S.2
Yen, B.C.3
Pietzsch, C.A.4
Sanchez-Aparicio, M.T.5
Tigabu, B.6
-
53
-
-
84991619059
-
Immunogenic cell death in cancer and infectious disease
-
Galluzzi, L., Buque, A., Kepp, O., Zitvogel, L., Kroemer, G., Immunogenic cell death in cancer and infectious disease. Nat. Rev. Immunol. 17 (2017), 97–111, 10.1038/nri.2016.107.
-
(2017)
Nat. Rev. Immunol.
, vol.17
, pp. 97-111
-
-
Galluzzi, L.1
Buque, A.2
Kepp, O.3
Zitvogel, L.4
Kroemer, G.5
-
54
-
-
84913586780
-
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
-
Sistigu, A., Yamazaki, T., Vacchelli, E., Chaba, K., Enot, D.P., Adam, J., et al. Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat. Med. 20 (2014), 1301–1309, 10.1038/nm.3708.
-
(2014)
Nat. Med.
, vol.20
, pp. 1301-1309
-
-
Sistigu, A.1
Yamazaki, T.2
Vacchelli, E.3
Chaba, K.4
Enot, D.P.5
Adam, J.6
-
55
-
-
84998636529
-
Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
-
Gaston, J., Cheradame, L., Yvonnet, V., Deas, O., Poupon, M.F., Judde, J.G., et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget 7 (2016), 77205–77224, 10.18632/oncotarget.12858.
-
(2016)
Oncotarget
, vol.7
, pp. 77205-77224
-
-
Gaston, J.1
Cheradame, L.2
Yvonnet, V.3
Deas, O.4
Poupon, M.F.5
Judde, J.G.6
-
56
-
-
35348960343
-
IFN-alpha and novel strategies of combination therapy for cancer
-
Bracci, L., Proietti, E., Belardelli, F., IFN-alpha and novel strategies of combination therapy for cancer. Ann. N. Y. Acad. Sci. 1112 (2007), 256–268, 10.1196/annals.1415.030.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1112
, pp. 256-268
-
-
Bracci, L.1
Proietti, E.2
Belardelli, F.3
-
57
-
-
84856301759
-
Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy
-
Proietti, E., Moschella, F., Capone, I., Belardelli, F., Exploitation of the propulsive force of chemotherapy for improving the response to cancer immunotherapy. Mol. Oncol. 6 (2012), 1–14, 10.1016/j.molonc.2011.11.005.
-
(2012)
Mol. Oncol.
, vol.6
, pp. 1-14
-
-
Proietti, E.1
Moschella, F.2
Capone, I.3
Belardelli, F.4
-
58
-
-
77951847280
-
Combination strategies for enhancing the efficacy of immunotherapy in cancer patients
-
Moschella, F., Proietti, E., Capone, I., Belardelli, F., Combination strategies for enhancing the efficacy of immunotherapy in cancer patients. Ann. N. Y. Acad. Sci. 1194 (2010), 169–178, 10.1111/j.1749-6632.2010.05464.x.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1194
, pp. 169-178
-
-
Moschella, F.1
Proietti, E.2
Capone, I.3
Belardelli, F.4
-
59
-
-
0034653477
-
Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer
-
Schiavoni, G., Mattei, F., Di Pucchio, T., Santini, S.M., Bracci, L., Belardelli, F., et al. Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer. Blood 95 (2000), 2024–2030.
-
(2000)
Blood
, vol.95
, pp. 2024-2030
-
-
Schiavoni, G.1
Mattei, F.2
Di Pucchio, T.3
Santini, S.M.4
Bracci, L.5
Belardelli, F.6
-
60
-
-
33846004208
-
Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells
-
Salem, M.L., Kadima, A.N., El-Naggar, S.A., Rubinstein, M.P., Chen, Y., Gillanders, W.E., et al. Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells. J. Immunother. 30 (2007), 40–53, 10.1097/01.cji.0000211311.28739.e3.
-
(2007)
J. Immunother.
, vol.30
, pp. 40-53
-
-
Salem, M.L.1
Kadima, A.N.2
El-Naggar, S.A.3
Rubinstein, M.P.4
Chen, Y.5
Gillanders, W.E.6
-
61
-
-
33846878993
-
Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration
-
Bracci, L., Moschella, F., Sestili, P., La Sorsa, V., Valentini, M., Canini, I., et al. Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration. Clin. Cancer Res. 13 (2007), 644–653, 10.1158/1078-0432.CCR-06-1209.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 644-653
-
-
Bracci, L.1
Moschella, F.2
Sestili, P.3
La Sorsa, V.4
Valentini, M.5
Canini, I.6
-
62
-
-
79551523389
-
Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis
-
Schiavoni, G., Sistigu, A., Valentini, M., Mattei, F., Sestili, P., Spadaro, F., et al. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. Cancer Res. 71 (2011), 768–778.
-
(2011)
Cancer Res.
, vol.71
, pp. 768-778
-
-
Schiavoni, G.1
Sistigu, A.2
Valentini, M.3
Mattei, F.4
Sestili, P.5
Spadaro, F.6
-
63
-
-
61449258305
-
Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)
-
Salem, M.L., Diaz-Montero, C.M., Al-Khami, A.A., El-Naggar, S.A., Naga, O., Montero, A.J., et al. Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C). J. Immunol. 182 (2009), 2030–2040.
-
(2009)
J. Immunol.
, vol.182
, pp. 2030-2040
-
-
Salem, M.L.1
Diaz-Montero, C.M.2
Al-Khami, A.A.3
El-Naggar, S.A.4
Naga, O.5
Montero, A.J.6
-
64
-
-
79956085853
-
Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide
-
Moschella, F., Valentini, M., Arico, E., Macchia, I., Sestili, P., D'Urso, M.T., et al. Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide. Cancer Res. 71 (2011), 3528–3539, 10.1158/0008-5472.CAN-10-4523.
-
(2011)
Cancer Res.
, vol.71
, pp. 3528-3539
-
-
Moschella, F.1
Valentini, M.2
Arico, E.3
Macchia, I.4
Sestili, P.5
D'Urso, M.T.6
-
65
-
-
84881233953
-
Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients' blood cells: implications for cancer chemoimmunotherapy
-
Moschella, F., Torelli, G.F., Valentini, M., Urbani, F., Buccione, C., Petrucci, M.T., et al. Cyclophosphamide induces a type I interferon-associated sterile inflammatory response signature in cancer patients' blood cells: implications for cancer chemoimmunotherapy. Clin. Cancer Res. 19 (2013), 4249–4261, 10.1158/1078-0432.CCR-12-3666.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 4249-4261
-
-
Moschella, F.1
Torelli, G.F.2
Valentini, M.3
Urbani, F.4
Buccione, C.5
Petrucci, M.T.6
-
66
-
-
84890283544
-
The Janus face of cyclophosphamide: a sterile inflammatory response that potentiates cancer immunotherapy
-
Ziccheddu, G., Proietti, E., Moschella, F., The Janus face of cyclophosphamide: a sterile inflammatory response that potentiates cancer immunotherapy. Oncoimmunology, 2, 2013, e25789, 10.4161/onci.25789.
-
(2013)
Oncoimmunology
, vol.2
, pp. e25789
-
-
Ziccheddu, G.1
Proietti, E.2
Moschella, F.3
-
67
-
-
58149376993
-
Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients
-
Nistico, P., Capone, I., Palermo, B., Del Bello, D., Ferraresi, V., Moschella, F., et al. Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients. Int. J. Cancer 124 (2009), 130–139, 10.1002/ijc.23886.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 130-139
-
-
Nistico, P.1
Capone, I.2
Palermo, B.3
Del Bello, D.4
Ferraresi, V.5
Moschella, F.6
-
68
-
-
84940381273
-
Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses
-
Chiappinelli, K.B., Strissel, P.L., Desrichard, A., Li, H., Henke, C., Akman, B., et al. Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses. Cell 162 (2015), 974–986, 10.1016/j.cell.2015.07.011.
-
(2015)
Cell
, vol.162
, pp. 974-986
-
-
Chiappinelli, K.B.1
Strissel, P.L.2
Desrichard, A.3
Li, H.4
Henke, C.5
Akman, B.6
-
69
-
-
84940403834
-
DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts
-
Roulois, D., Loo Yau, H., Singhania, R., Wang, Y., Danesh, A., Shen, S.Y., et al. DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts. Cell 162 (2015), 961–973, 10.1016/j.cell.2015.07.056.
-
(2015)
Cell
, vol.162
, pp. 961-973
-
-
Roulois, D.1
Loo Yau, H.2
Singhania, R.3
Wang, Y.4
Danesh, A.5
Shen, S.Y.6
-
70
-
-
79955570584
-
Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
-
Stagg, J., Loi, S., Divisekera, U., Ngiow, S.F., Duret, H., Yagita, H., et al. Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 7142–7147, 10.1073/pnas.1016569108.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 7142-7147
-
-
Stagg, J.1
Loi, S.2
Divisekera, U.3
Ngiow, S.F.4
Duret, H.5
Yagita, H.6
-
71
-
-
84946729972
-
Interferons and the immunogenic effects of cancer therapy
-
Minn, A.J., Interferons and the immunogenic effects of cancer therapy. Trends Immunol. 36 (2015), 725–737, 10.1016/j.it.2015.09.007.
-
(2015)
Trends Immunol.
, vol.36
, pp. 725-737
-
-
Minn, A.J.1
-
72
-
-
84949681428
-
The good and the bad faces of STAT1 in solid tumours
-
Meissl, K., Macho-Maschler, S., Muller, M., Strobl, B., The good and the bad faces of STAT1 in solid tumours. Cytokine 89 (2017), 12–20, 10.1016/j.cyto.2015.11.011.
-
(2017)
Cytokine
, vol.89
, pp. 12-20
-
-
Meissl, K.1
Macho-Maschler, S.2
Muller, M.3
Strobl, B.4
-
73
-
-
84876311772
-
Persistent LCMV infection is controlled by blockade of type I interferon signaling
-
Teijaro, J.R., Ng, C., Lee, A.M., Sullivan, B.M., Sheehan, K.C., Welch, M., et al. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science 340 (2013), 207–211, 10.1126/science.1235214.
-
(2013)
Science
, vol.340
, pp. 207-211
-
-
Teijaro, J.R.1
Ng, C.2
Lee, A.M.3
Sullivan, B.M.4
Sheehan, K.C.5
Welch, M.6
-
74
-
-
84876299371
-
Blockade of chronic type I interferon signaling to control persistent LCMV infection
-
Wilson, E.B., Yamada, D.H., Elsaesser, H., Herskovitz, J., Deng, J., Cheng, G., et al. Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science 340 (2013), 202–207, 10.1126/science.1235208.
-
(2013)
Science
, vol.340
, pp. 202-207
-
-
Wilson, E.B.1
Yamada, D.H.2
Elsaesser, H.3
Herskovitz, J.4
Deng, J.5
Cheng, G.6
-
75
-
-
1242319531
-
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells
-
Khodarev, N.N., Beckett, M., Labay, E., Darga, T., Roizman, B., Weichselbaum, R.R., STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 1714–1719, 10.1073/pnas.0308102100.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 1714-1719
-
-
Khodarev, N.N.1
Beckett, M.2
Labay, E.3
Darga, T.4
Roizman, B.5
Weichselbaum, R.R.6
-
76
-
-
35148879113
-
Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells
-
Khodarev, N.N., Minn, A.J., Efimova, E.V., Darga, T.E., Labay, E., Beckett, M., et al. Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells. Cancer Res. 67 (2007), 9214–9220, 10.1158/0008-5472.CAN-07-1019.
-
(2007)
Cancer Res.
, vol.67
, pp. 9214-9220
-
-
Khodarev, N.N.1
Minn, A.J.2
Efimova, E.V.3
Darga, T.E.4
Labay, E.5
Beckett, M.6
-
77
-
-
79958786755
-
STAT1 promotes radioresistance of CD44(+)/CD24(-/low) cells in breast cancer
-
Zhan, J.F., Chen, L.H., Yuan, Y.W., Xie, G.Z., Sun, A.M., Liu, Y., et al. STAT1 promotes radioresistance of CD44(+)/CD24(-/low) cells in breast cancer. Exp. Biol. Med. (Maywood) 236 (2011), 418–422, 10.1258/ebm.2011.010287.
-
(2011)
Exp. Biol. Med. (Maywood)
, vol.236
, pp. 418-422
-
-
Zhan, J.F.1
Chen, L.H.2
Yuan, Y.W.3
Xie, G.Z.4
Sun, A.M.5
Liu, Y.6
-
78
-
-
57449088412
-
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
-
Weichselbaum, R.R., Ishwaran, H., Yoon, T., Nuyten, D.S., Baker, S.W., Khodarev, N., et al. An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 18490–18495, 10.1073/pnas.0809242105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 18490-18495
-
-
Weichselbaum, R.R.1
Ishwaran, H.2
Yoon, T.3
Nuyten, D.S.4
Baker, S.W.5
Khodarev, N.6
-
79
-
-
24944521677
-
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
-
Rickardson, L., Fryknas, M., Dhar, S., Lovborg, H., Gullbo, J., Rydaker, M., et al. Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. Br. J. Cancer 93 (2005), 483–492, 10.1038/sj.bjc.6602699.
-
(2005)
Br. J. Cancer
, vol.93
, pp. 483-492
-
-
Rickardson, L.1
Fryknas, M.2
Dhar, S.3
Lovborg, H.4
Gullbo, J.5
Rydaker, M.6
-
80
-
-
17444362227
-
Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
-
Roberts, D., Schick, J., Conway, S., Biade, S., Laub, P.B., Stevenson, J.P., et al. Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells. Br. J. Cancer 92 (2005), 1149–1158, 10.1038/sj.bjc.6602447.
-
(2005)
Br. J. Cancer
, vol.92
, pp. 1149-1158
-
-
Roberts, D.1
Schick, J.2
Conway, S.3
Biade, S.4
Laub, P.B.5
Stevenson, J.P.6
-
81
-
-
84908275360
-
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
-
Boelens, M.C., Wu, T.J., Nabet, B.Y., Xu, B., Qiu, Y., Yoon, T., et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 159 (2014), 499–513, 10.1016/j.cell.2014.09.051.
-
(2014)
Cell
, vol.159
, pp. 499-513
-
-
Boelens, M.C.1
Wu, T.J.2
Nabet, B.Y.3
Xu, B.4
Qiu, Y.5
Yoon, T.6
-
82
-
-
67249144899
-
Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes
-
Cheon, H., Stark, G.R., Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 9373–9378, 10.1073/pnas.0903487106.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 9373-9378
-
-
Cheon, H.1
Stark, G.R.2
-
83
-
-
84885869823
-
IFNbeta-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
-
Cheon, H., Holvey-Bates, E.G., Schoggins, J.W., Forster, S., Hertzog, P., Imanaka, N., et al. IFNbeta-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage. EMBO J. 32 (2013), 2751–2763, 10.1038/emboj.2013.203.
-
(2013)
EMBO J.
, vol.32
, pp. 2751-2763
-
-
Cheon, H.1
Holvey-Bates, E.G.2
Schoggins, J.W.3
Forster, S.4
Hertzog, P.5
Imanaka, N.6
-
84
-
-
84893075305
-
Regulation of type I interferon responses
-
Ivashkiv, L.B., Donlin, L.T., Regulation of type I interferon responses. Nat. Rev. Immunol. 14 (2014), 36–49, 10.1038/nri3581.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 36-49
-
-
Ivashkiv, L.B.1
Donlin, L.T.2
-
85
-
-
33847401888
-
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion
-
Blank, C., Mackensen, A., Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol. Immunother. 56 (2007), 739–745, 10.1007/s00262-006-0272-1.
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, pp. 739-745
-
-
Blank, C.1
Mackensen, A.2
-
86
-
-
85006746576
-
Combining type I interferons and 5-Aza-2'-deoxycitidine to improve anti-tumor response against melanoma
-
Lucarini, V., Buccione, C., Ziccheddu, G., Peschiaroli, F., Sestili, P., Puglisi, R., et al. Combining type I interferons and 5-Aza-2'-deoxycitidine to improve anti-tumor response against melanoma. J. Invest. Dermatol. 137 (2017), 159–169, 10.1016/j.jid.2016.08.024.
-
(2017)
J. Invest. Dermatol.
, vol.137
, pp. 159-169
-
-
Lucarini, V.1
Buccione, C.2
Ziccheddu, G.3
Peschiaroli, F.4
Sestili, P.5
Puglisi, R.6
-
87
-
-
84926525215
-
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
-
Twyman-Saint Victor, C., Rech, A.J., Maity, A., Rengan, R., Pauken, K.E., Stelekati, E., et al. Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature 520 (2015), 373–377, 10.1038/nature14292.
-
(2015)
Nature
, vol.520
, pp. 373-377
-
-
Twyman-Saint Victor, C.1
Rech, A.J.2
Maity, A.3
Rengan, R.4
Pauken, K.E.5
Stelekati, E.6
-
88
-
-
85001996779
-
Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade
-
(e12)
-
Benci, J.L., Xu, B., Qiu, Y., Wu, T.J., Dada, H., Twyman-Saint Victor, C., et al. Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade. Cell 167 (2016), 1540–1554, 10.1016/j.cell.2016.11.022 (e12).
-
(2016)
Cell
, vol.167
, pp. 1540-1554
-
-
Benci, J.L.1
Xu, B.2
Qiu, Y.3
Wu, T.J.4
Dada, H.5
Twyman-Saint Victor, C.6
-
89
-
-
84904055758
-
Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation
-
Bald, T., Landsberg, J., Lopez-Ramos, D., Renn, M., Glodde, N., Jansen, P., et al. Immune cell-poor melanomas benefit from PD-1 blockade after targeted type I IFN activation. Cancer Discov. 4 (2014), 674–687, 10.1158/2159-8290.CD-13-0458.
-
(2014)
Cancer Discov.
, vol.4
, pp. 674-687
-
-
Bald, T.1
Landsberg, J.2
Lopez-Ramos, D.3
Renn, M.4
Glodde, N.5
Jansen, P.6
-
90
-
-
0036102949
-
Type I interferon gene transfer sensitizes melanoma cells to apoptosis via a target activity on mitochondrial function
-
Matarrese, P., Di Biase, L., Santodonato, L., Straface, E., Mecchia, M., Ascione, B., et al. Type I interferon gene transfer sensitizes melanoma cells to apoptosis via a target activity on mitochondrial function. Am. J. Pathol. 160 (2002), 1507–1520, 10.1016/S0002-9440(10)62577-1.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1507-1520
-
-
Matarrese, P.1
Di Biase, L.2
Santodonato, L.3
Straface, E.4
Mecchia, M.5
Ascione, B.6
-
91
-
-
4043150782
-
Effectiveness of Type I interferons in the treatment of multidrug resistant osteosarcoma cells
-
Manara, M.C., Serra, M., Benini, S., Picci, P., Scotlandi, K., Effectiveness of Type I interferons in the treatment of multidrug resistant osteosarcoma cells. Int. J. Oncol. 24 (2004), 365–372.
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 365-372
-
-
Manara, M.C.1
Serra, M.2
Benini, S.3
Picci, P.4
Scotlandi, K.5
-
92
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean, M., Fojo, T., Bates, S., Tumour stem cells and drug resistance. Nat. Rev. Cancer 5 (2005), 275–284, 10.1038/nrc1590.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
93
-
-
84901011473
-
Influence of interferon-alpha on the expression of the cancer stem cell markers in pancreatic carcinoma cells
-
Zhu, Y., Karakhanova, S., Huang, X., Deng, S.P., Werner, J., Bazhin, A.V., Influence of interferon-alpha on the expression of the cancer stem cell markers in pancreatic carcinoma cells. Exp. Cell Res. 324 (2014), 146–156, 10.1016/j.yexcr.2014.03.020.
-
(2014)
Exp. Cell Res.
, vol.324
, pp. 146-156
-
-
Zhu, Y.1
Karakhanova, S.2
Huang, X.3
Deng, S.P.4
Werner, J.5
Bazhin, A.V.6
-
94
-
-
36048933772
-
Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/lymphoma
-
Kayo, H., Yamazaki, H., Nishida, H., Dang, N.H., Morimoto, C., Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/lymphoma. Biochem. Biophys. Res. Commun. 364 (2007), 808–814, 10.1016/j.bbrc.2007.10.070.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.364
, pp. 808-814
-
-
Kayo, H.1
Yamazaki, H.2
Nishida, H.3
Dang, N.H.4
Morimoto, C.5
-
95
-
-
84939826013
-
Comparative study of the effects of PEGylated interferon-alpha2a versus 5-fluorouracil on cancer stem cells in a rat model of hepatocellular carcinoma
-
Motawi, T.K., El-Boghdady, N.A., El-Sayed, A.M., Helmy, H.S., Comparative study of the effects of PEGylated interferon-alpha2a versus 5-fluorouracil on cancer stem cells in a rat model of hepatocellular carcinoma. Tumour Biol. 37 (2016), 1617–1625, 10.1007/s13277-015-3920-2.
-
(2016)
Tumour Biol.
, vol.37
, pp. 1617-1625
-
-
Motawi, T.K.1
El-Boghdady, N.A.2
El-Sayed, A.M.3
Helmy, H.S.4
-
96
-
-
84860237519
-
Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine
-
Hayashi, T., Ding, Q., Kuwahata, T., Maeda, K., Miyazaki, Y., Matsubara, S., et al. Interferon-alpha modulates the chemosensitivity of CD133-expressing pancreatic cancer cells to gemcitabine. Cancer Sci. 103 (2012), 889–896, 10.1111/j.1349-7006.2012.02235.x.
-
(2012)
Cancer Sci.
, vol.103
, pp. 889-896
-
-
Hayashi, T.1
Ding, Q.2
Kuwahata, T.3
Maeda, K.4
Miyazaki, Y.5
Matsubara, S.6
-
97
-
-
84967333660
-
IFN-alpha potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer
-
Buoncervello, M., Romagnoli, G., Buccarelli, M., Fragale, A., Toschi, E., Parlato, S., et al. IFN-alpha potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer. Oncotarget 7 (2016), 26361–26373, 10.18632/oncotarget.8379.
-
(2016)
Oncotarget
, vol.7
, pp. 26361-26373
-
-
Buoncervello, M.1
Romagnoli, G.2
Buccarelli, M.3
Fragale, A.4
Toschi, E.5
Parlato, S.6
-
98
-
-
66149115277
-
IFNalpha activates dormant haematopoietic stem cells in vivo
-
Essers, M.A., Offner, S., Blanco-Bose, W.E., Waibler, Z., Kalinke, U., Duchosal, M.A., et al. IFNalpha activates dormant haematopoietic stem cells in vivo. Nature 458 (2009), 904–908.
-
(2009)
Nature
, vol.458
, pp. 904-908
-
-
Essers, M.A.1
Offner, S.2
Blanco-Bose, W.E.3
Waibler, Z.4
Kalinke, U.5
Duchosal, M.A.6
-
99
-
-
77649119006
-
Awakening dormant haematopoietic stem cells
-
Trumpp, A., Essers, M., Wilson, A., Awakening dormant haematopoietic stem cells. Nat. Rev. Immunol. 10 (2010), 201–209, 10.1038/nri2726.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 201-209
-
-
Trumpp, A.1
Essers, M.2
Wilson, A.3
-
100
-
-
78349310882
-
Mechanism of synergistic antitumor effect of sorafenib and interferon-alpha on treatment of renal cell carcinoma
-
Takeuchi, A., Eto, M., Tatsugami, K., Yamada, H., Oki, T., Kiyoshima, K., et al. Mechanism of synergistic antitumor effect of sorafenib and interferon-alpha on treatment of renal cell carcinoma. J. Urol. 184 (2010), 2549–2556, 10.1016/j.juro.2010.07.033.
-
(2010)
J. Urol.
, vol.184
, pp. 2549-2556
-
-
Takeuchi, A.1
Eto, M.2
Tatsugami, K.3
Yamada, H.4
Oki, T.5
Kiyoshima, K.6
|