STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells

Journal of Immunology

Volumn 193, Issue 12, 2014, Pages 6124-6134

  Klarquist, Jared ^a   Hennies, Cassandra M ^a   Lehn, Maria A ^a   Reboulet, Rachel A ^a   Feau, Sonia ^b   Janssen, Edith M ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ANTINUCLEAR ANTIBODY; CELL NUCLEUS DNA; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 3; STING PROTEIN; TOLL LIKE RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG; ANTIGEN; DNA; INTERFERON; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; HELPER CELL; INTERFERON PRODUCTION; MELANOMA B16; MOUSE; NONHUMAN; PLASMA CELL; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; CELL DEATH; DISEASE MODEL; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; NEOPLASM; SIGNAL TRANSDUCTION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS; AUTOIMMUNITY; B-LYMPHOCYTE SUBSETS; CELL DEATH; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; DNA; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEOPLASMS; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS;

EID: 84916894965     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401869     Document Type: Article

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