Metabolite measurement: Pitfalls to avoid and practices to follow

Annual Review of Biochemistry

Volumn 86, Issue , 2017, Pages 277-304

  Lu, Wenyun ^a   Su, Xiaoyang ^a   Klein, Matthias S ^b   Lewis, Ian A ^b   Fiehn, Oliver ^c,d   Rabinowitz, Joshua D ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Accuracy; Mass spectroscopy; Metabolite extraction; Metabolomics; Metabonomics; Stability

Indexed keywords

ACETONITRILE; ADENOSINE TRIPHOSPHATE; ENZYME; GLUTATHIONE; METHANOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; WATER; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLVENT;

DEGRADATION; ENZYME ASSAY; EXTRACTION; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MASS FRAGMENTOGRAPHY; METABOLITE; METABOLOMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REVIEW; ANIMAL; DEVICES; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID PHASE MICROEXTRACTION; MASS SPECTROMETRY; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRACTICE GUIDELINE; PROCEDURES; STANDARDS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHROMATOGRAPHY, LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUTATHIONE; GUIDELINES AS TOPIC; HUMANS; LIQUID PHASE MICROEXTRACTION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; METABOLOMICS; MICE; NADP; SOLVENTS;

EID: 85021631678     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-061516-044952     Document Type: Review

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