-
1
-
-
84857672615
-
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism
-
Buescher, J.M. et al. Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism. Science 335, 1099-1103 (2012).
-
(2012)
Science
, vol.335
, pp. 1099-1103
-
-
Buescher, J.M.1
-
2
-
-
84858433310
-
Personal omics profiling reveals dynamic molecular and medical phenotypes
-
Chen, R. et al. Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell 148, 1293-1307 (2012).
-
(2012)
Cell
, vol.148
, pp. 1293-1307
-
-
Chen, R.1
-
3
-
-
84877296949
-
Systematic identification of allosteric protein-metabolite interactions that control enzyme activity in vivo
-
Link, H., Kochanowski, K. & Sauer, U. Systematic identification of allosteric protein-metabolite interactions that control enzyme activity in vivo. Nat. Biotechnol. 31, 357-361 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 357-361
-
-
Link, H.1
Kochanowski, K.2
Sauer, U.3
-
4
-
-
84861455370
-
Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase
-
Xu, Y.-F., Amador-Noguez, D., Reaves, M.L., Feng, X.-J. & Rabinowitz, J.D. Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase. Nat. Chem. Biol. 8, 562-568 (2012).
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 562-568
-
-
Xu, Y.-F.1
Amador-Noguez, D.2
Reaves, M.L.3
Feng, X.-J.4
Rabinowitz, J.D.5
-
5
-
-
81355127364
-
α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme i inhibition
-
Doucette, C.D., Schwab, D.J., Wingreen, N.S. & Rabinowitz, J.D. α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition. Nat. Chem. Biol. 7, 894-901 (2011).
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 894-901
-
-
Doucette, C.D.1
Schwab, D.J.2
Wingreen, N.S.3
Rabinowitz, J.D.4
-
6
-
-
84899047521
-
Coordination of microbial metabolism
-
Chubukov, V., Gerosa, L., Kochanowski, K. & Sauer, U. Coordination of microbial metabolism. Nat. Rev. Microbiol. 12, 327-340 (2014).
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 327-340
-
-
Chubukov, V.1
Gerosa, L.2
Kochanowski, K.3
Sauer, U.4
-
7
-
-
77952545479
-
Metabolic oxidation regulates embryonic stem cell differentiation
-
Yanes, O. et al. Metabolic oxidation regulates embryonic stem cell differentiation. Nat. Chem. Biol. 6, 411-417 (2010).
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 411-417
-
-
Yanes, O.1
-
8
-
-
84861420588
-
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
-
Jain, M. et al. Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation. Science 336, 1040-1044 (2012).
-
(2012)
Science
, vol.336
, pp. 1040-1044
-
-
Jain, M.1
-
9
-
-
80052785690
-
High-Dhroughput accurate mass metabolome profiling of cellular extracts by flow injection-Dime-of-flight mass spectrometry
-
Fuhrer, T., Heer, D., Begemann, B. & Zamboni, N. High-Dhroughput, accurate mass metabolome profiling of cellular extracts by flow injection-Dime-of-flight mass spectrometry. Anal. Chem. 83, 7074-7080 (2011).
-
(2011)
Anal. Chem.
, vol.83
, pp. 7074-7080
-
-
Fuhrer, T.1
Heer, D.2
Begemann, B.3
Zamboni, N.4
-
11
-
-
77953206924
-
Stationary phase in gram-negative bacteria
-
Navarro Llorens, J.M., Tormo, A. & Martínez-García, E. Stationary phase in gram-negative bacteria. FEMS Microbiol. Rev. 34, 476-495 (2010).
-
(2010)
FEMS Microbiol. Rev.
, vol.34
, pp. 476-495
-
-
Navarro Llorens, J.M.1
Tormo, A.2
Martínez-García, E.3
-
12
-
-
84874566685
-
Changes in substrate availability in Escherichia coli lead to rapid metabolite, flux and growth rate responses
-
Taymaz-Nikerel, H. et al. Changes in substrate availability in Escherichia coli lead to rapid metabolite, flux and growth rate responses. Metab. Eng. 16, 115-129 (2013).
-
(2013)
Metab. Eng.
, vol.16
, pp. 115-129
-
-
Taymaz-Nikerel, H.1
-
13
-
-
33845870439
-
Conservation of the metabolomic response to starvation across two divergent microbes
-
Brauer, M.J. et al. Conservation of the metabolomic response to starvation across two divergent microbes. Proc. Natl. Acad. Sci. USA 103, 19302-19307 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19302-19307
-
-
Brauer, M.J.1
-
14
-
-
1942455714
-
RMF inactivates ribosomes by covering the peptidyl transferase centre and entrance of peptide exit tunnel
-
Yoshida, H., Yamamoto, H., Uchiumi, T. & Wada, A. RMF inactivates ribosomes by covering the peptidyl transferase centre and entrance of peptide exit tunnel. Genes Cells 9, 271-278 (2004).
-
(2004)
Genes Cells
, vol.9
, pp. 271-278
-
-
Yoshida, H.1
Yamamoto, H.2
Uchiumi, T.3
Wada, A.4
-
15
-
-
79955065138
-
Optimization of a blueprint for in vitro glycolysis by metabolic real-Dime analysis
-
Bujara, M., Schümperli, M., Pellaux, R., Heinemann, M. & Panke, S. Optimization of a blueprint for in vitro glycolysis by metabolic real-Dime analysis. Nat. Chem. Biol. 7, 271-277 (2011).
-
(2011)
Nat. Chem. Biol.
, Issue.7
, pp. 271-277
-
-
Bujara, M.1
Schümperli, M.2
Pellaux, R.3
Heinemann, M.4
Panke, S.5
-
16
-
-
80054069179
-
A comprehensive genome-scale reconstruction of Escherichia coli metabolism-2011
-
Orth, J.D. et al. A comprehensive genome-scale reconstruction of Escherichia coli metabolism-2011. Mol. Syst. Biol. 7, 535 (2011).
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 535
-
-
Orth, J.D.1
-
17
-
-
34548023950
-
Acidic acetonitrile for cellular metabolome extraction from Escherichia coli
-
Rabinowitz, J.D. & Kimball, E. Acidic acetonitrile for cellular metabolome extraction from Escherichia coli. Anal. Chem. 79, 6167-6173 (2007).
-
(2007)
Anal. Chem.
, vol.79
, pp. 6167-6173
-
-
Rabinowitz, J.D.1
Kimball, E.2
-
18
-
-
77952985821
-
Ultrahigh performance liquid chromatography-Dandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites
-
Buescher, J.M., Moco, S., Sauer, U. & Zamboni, N. Ultrahigh performance liquid chromatography-Dandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites. Anal. Chem. 82, 4403-4412 (2010).
-
(2010)
Anal. Chem.
, vol.82
, pp. 4403-4412
-
-
Buescher, J.M.1
Moco, S.2
Sauer, U.3
Zamboni, N.4
-
19
-
-
77955485602
-
Protein S-Dhiolation by Glutathionylspermidine (Gsp): The role of Escherichia coli Gsp synthetASE/amidase in redox regulation
-
Chiang, B.-Y. et al. Protein S-Dhiolation by Glutathionylspermidine (Gsp): the role of Escherichia coli Gsp synthetASE/amidase in redox regulation. J. Biol. Chem. 285, 25345-25353 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25345-25353
-
-
Chiang, B.-Y.1
-
20
-
-
0021359099
-
Role of protein degradation in the survival of carbon-starved Escherichia coli and Salmonella typhimurium
-
Reeve, C.A., Bockman, A.T. & Matin, A. Role of protein degradation in the survival of carbon-starved Escherichia coli and Salmonella typhimurium. J. Bacteriol. 157, 758-763 (1984).
-
(1984)
J. Bacteriol.
, vol.157
, pp. 758-763
-
-
Reeve, C.A.1
Bockman, A.T.2
Matin, A.3
-
21
-
-
33748878445
-
Kinetic flux profiling of nitrogen assimilation in Escherichia coli
-
Yuan, J., Fowler, W.U., Kimball, E., Lu, W. & Rabinowitz, J.D. Kinetic flux profiling of nitrogen assimilation in Escherichia coli. Nat. Chem. Biol. 2, 529-530 (2006).
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 529-530
-
-
Yuan, J.1
Fowler, W.U.2
Kimball, E.3
Lu, W.4
Rabinowitz, J.D.5
-
22
-
-
0037133671
-
Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis
-
Akashi, H. & Gojobori, T. Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis. Proc. Natl. Acad. Sci. USA 99, 3695-3700 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3695-3700
-
-
Akashi, H.1
Gojobori, T.2
-
23
-
-
75549087930
-
BioNumbers-Dhe database of key numbers in molecular and cell biology
-
Milo, R., Jorgensen, P., Moran, U., Weber, G. & Springer, M. BioNumbers-Dhe database of key numbers in molecular and cell biology. Nucleic Acids Res. 38, D750-D753 (2010).
-
(2010)
Nucleic Acids Res.
, Issue.38
, pp. D750-D753
-
-
Milo, R.1
Jorgensen, P.2
Moran, U.3
Weber, G.4
Springer, M.5
-
24
-
-
77955501572
-
Achieving optimal growth through product feedback inhibition in metabolism
-
Goyal, S., Yuan, J., Chen, T., Rabinowitz, J.D. & Wingreen, N.S. Achieving optimal growth through product feedback inhibition in metabolism. PLoS Comput. Biol. 6, e1000802 (2010).
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. e1000802
-
-
Goyal, S.1
Yuan, J.2
Chen, T.3
Rabinowitz, J.D.4
Wingreen, N.S.5
-
25
-
-
0000941724
-
Switches thresholds and ultrasensitivity
-
Koshland, D.E. Switches, thresholds and ultrasensitivity. Trends Biochem. Sci. 12, 225-229 (1987).
-
(1987)
Trends Biochem. Sci.
, vol.12
, pp. 225-229
-
-
Koshland, D.E.1
-
26
-
-
28844476573
-
Dissection of Escherichia coli glutamate 5-kinase: Functional impact of the deletion of the PUA domain
-
Pérez-Arellano, I., Rubio, V. & Cervera, J. Dissection of Escherichia coli glutamate 5-kinase: functional impact of the deletion of the PUA domain. FEBS Lett. 579, 6903-6908 (2005).
-
(2005)
FEBS Lett.
, vol.579
, pp. 6903-6908
-
-
Pérez-Arellano, I.1
Rubio, V.2
Cervera, J.3
-
27
-
-
0028827680
-
Entry of Escherichia coli into stationary phase is indicated by endogenous and exogenous accumulation of nucleobases
-
Rinas, U., Hellmuth, K., Kang, R., Seeger, A. & Schlieker, H. Entry of Escherichia coli into stationary phase is indicated by endogenous and exogenous accumulation of nucleobases. Appl. Environ. Microbiol. 61, 4147-4151 (1995).
-
(1995)
Appl. Environ. Microbiol.
, vol.61
, pp. 4147-4151
-
-
Rinas, U.1
Hellmuth, K.2
Kang, R.3
Seeger, A.4
Schlieker, H.5
-
28
-
-
0021848247
-
Purification and characterization of Escherichia coli xanthine-guanine phosphoribosyltransferase produced by plasmid pSV2gpt
-
Deo, S.S., Tseng, W.C., Saini, R., Coles, R.S. & Athwal, R.S. Purification and characterization of Escherichia coli xanthine-guanine phosphoribosyltransferase produced by plasmid pSV2gpt. Biochim. Biophys. Acta 839, 233-239 (1985).
-
(1985)
Biochim. Biophys. Acta
, vol.839
, pp. 233-239
-
-
Deo, S.S.1
Tseng, W.C.2
Saini, R.3
Coles, R.S.4
Athwal, R.S.5
-
29
-
-
0027196848
-
Identification of sites for feedback regulation of glutamine 5-phosphoribosylpyrophosphate amidotransferase by nucleotides and relationship to residues important for catalysis
-
Zhou, G., Charbonneau, H., Colman, R.F. & Zalkin, H. Identification of sites for feedback regulation of glutamine 5-phosphoribosylpyrophosphate amidotransferase by nucleotides and relationship to residues important for catalysis. J. Biol. Chem. 268, 10471-10481 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10471-10481
-
-
Zhou, G.1
Charbonneau, H.2
Colman, R.F.3
Zalkin, H.4
-
30
-
-
84880871430
-
Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate
-
Fridman, A. et al. Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate. Biochem. J. 454, 91-99 (2013).
-
(2013)
Biochem. J.
, vol.454
, pp. 91-99
-
-
Fridman, A.1
-
31
-
-
0017305702
-
Intracellular 5-phosphoribosyl-1-pyrophosphate: Decreased availability during glutamine limitation
-
Skaper, S.D., Willis, R.C. & Seegmiller, J.E. Intracellular 5-phosphoribosyl-1-pyrophosphate: decreased availability during glutamine limitation. Science 193, 587-588 (1976).
-
(1976)
Science
, vol.193
, pp. 587-588
-
-
Skaper, S.D.1
Willis, R.C.2
Seegmiller, J.E.3
-
32
-
-
34147164666
-
Effect of amplification of desensitized purF and prs on inosine accumulation in Escherichia coli
-
Shimaoka, M., Takenaka, Y., Kurahashi, O., Kawasaki, H. & Matsui, H. Effect of amplification of desensitized purF and prs on inosine accumulation in Escherichia coli. J. Biosci. Bioeng. 103, 255-261 (2007).
-
(2007)
J. Biosci. Bioeng.
, vol.103
, pp. 255-261
-
-
Shimaoka, M.1
Takenaka, Y.2
Kurahashi, O.3
Kawasaki, H.4
Matsui, H.5
-
33
-
-
84891352625
-
Promoter activity dynamics in the lag phase of Escherichia coli
-
Madar, D. et al. Promoter activity dynamics in the lag phase of Escherichia coli. BMC Syst. Biol. 7, 136 (2013).
-
(2013)
BMC Syst. Biol.
, vol.7
, pp. 136
-
-
Madar, D.1
-
34
-
-
84856762359
-
Optimality in the development of intestinal crypts
-
Itzkovitz, S., Blat, I.C., Jacks, T., Clevers, H. & van Oudenaarden, A. Optimality in the development of intestinal crypts. Cell 148, 608-619 (2012).
-
(2012)
Cell
, vol.148
, pp. 608-619
-
-
Itzkovitz, S.1
Blat, I.C.2
Jacks, T.3
Clevers, H.4
Van Oudenaarden, A.5
-
35
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
2006.0008
-
Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
-
(2006)
Mol. Syst. Biol.
, vol.2
-
-
Baba, T.1
-
36
-
-
79953882386
-
Intracellular characterization of aerobic glucose metabolism in seven yeast species by 13C flux analysis and metabolomics
-
Christen, S. & Sauer, U. Intracellular characterization of aerobic glucose metabolism in seven yeast species by 13C flux analysis and metabolomics. FEMS Yeast Res. 11, 263-272 (2011).
-
(2011)
FEMS Yeast Res.
, vol.11
, pp. 263-272
-
-
Christen, S.1
Sauer, U.2
-
37
-
-
79251556819
-
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains
-
Canelas, A.B. et al. Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. Nat. Commun. 1, 145 (2010).
-
(2010)
Nat. Commun.
, vol.1
, pp. 145
-
-
Canelas, A.B.1
|