Morusin shows potent antitumor activity for human hepatocellular carcinoma in vitro and in vivo through apoptosis induction and angiogenesis inhibition

Drug Design, Development and Therapy

Volumn 11, Issue , 2017, Pages 1789-1802

  Gao, Ling ^a   Wang, Li ^a   Sun, Zhen ^b   Li, Haiyan ^b   Wang, Qiaoping ^b   Yi, Cheng ^a   Wang, Xiujie ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Angiogenesis; Apoptosis; Human hepatocellular carcinoma; IL 6; Morusin; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; INTERLEUKIN 6; MORUSIN; PROTEIN BAX; PROTEIN BCL 2; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANGIOGENESIS INHIBITOR; FLAVONOID; IL6 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MIGRATION INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER TRANSPLANTATION; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; LIVER TUMOR; TUMOR CELL LINE; TUMOR STEM CELL ASSAY;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; FLAVONOIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-6; LIVER NEOPLASMS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; STAT3 TRANSCRIPTION FACTOR; TUMOR STEM CELL ASSAY;

EID: 85021121540     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S138320     Document Type: Article

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