메뉴 건너뛰기




Volumn 379, Issue 1-2, 2013, Pages 7-18

Morusin inhibits human cervical cancer stem cell growth and migration through attenuation of NF-κB activity and apoptosis induction

Author keywords

Apoptosis; Cancer stem cells; Cancer stem markers; Cervical cancer; Growth inhibition; Morusin

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ANTINEOPLASTIC AGENT; CASPASE 3; FLAVONOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MORUSIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN BAX; PROTEIN BCL 2; SYNAPTOTAGMIN I; TOLONIUM CHLORIDE; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 84878433037     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1621-y     Document Type: Article
Times cited : (89)

References (41)
  • 3
    • 0035828388 scopus 로고    scopus 로고
    • Survival and recurrence after concomitant chemo-therapy and radiotherapy for cancer of the uterine cervix: A systematic review and meta-analysis
    • 11564482 10.1016/S0140-6736(01)05965-7 1:STN:280:DC%2BD3MrhslOgtA%3D%3D
    • Green JA, Kirwan JM, Tierney JF, Symonds P, Fresco L, Collingwood M, Williams CJ (2001) Survival and recurrence after concomitant chemo-therapy and radiotherapy for cancer of the uterine cervix: a systematic review and meta-analysis. Lancet 358:781-786
    • (2001) Lancet , vol.358 , pp. 781-786
    • Green, J.A.1    Kirwan, J.M.2    Tierney, J.F.3    Symonds, P.4    Fresco, L.5    Collingwood, M.6    Williams, C.J.7
  • 5
    • 33750437419 scopus 로고    scopus 로고
    • First among equals: The cancer cell hierarchy
    • 17071472 10.1080/10428190600733325 1:CAS:528:DC%2BD28XhtlCiurfF
    • Ichim CV, Wells RA (2006) First among equals: the cancer cell hierarchy. Leuk Lymphoma 47:2017-2027
    • (2006) Leuk Lymphoma , vol.47 , pp. 2017-2027
    • Ichim, C.V.1    Wells, R.A.2
  • 6
    • 77956262988 scopus 로고    scopus 로고
    • Maintenance of critical properties of brain tumor stem-like cells after cryopreservation
    • 20155395 10.1007/s10571-010-9505-0
    • Mao XG, Guo G, Wang P, Zhang X, Xue XY, Zhang W, Fei Z, Jiang XF, Yan M (2010) Maintenance of critical properties of brain tumor stem-like cells after cryopreservation. Cell Mol Neurobiol 30:775-786
    • (2010) Cell Mol Neurobiol , vol.30 , pp. 775-786
    • Mao, X.G.1    Guo, G.2    Wang, P.3    Zhang, X.4    Xue, X.Y.5    Zhang, W.6    Fei, Z.7    Jiang, X.F.8    Yan, M.9
  • 7
    • 84878275887 scopus 로고    scopus 로고
    • Breast cancer stem cells: An update
    • doi: 10.1136/jclinpath-2012-201304
    • Iqbal J, Chong PY, Tan PH (2013) Breast cancer stem cells: an update. J Clin Pathol. doi: 10.1136/jclinpath-2012-201304
    • (2013) J Clin Pathol.
    • Iqbal, J.1    Chong, P.Y.2    Tan, P.H.3
  • 8
    • 79961026922 scopus 로고    scopus 로고
    • Direct reprogramming of stem cell properties in colon cancer cells by CD44
    • 21701559 10.1038/emboj.2011.211 1:CAS:528:DC%2BC3MXnvFOqsLc%3D
    • Su YJ, Lai HM, Chang YW, Chen GY, Lee JL (2011) Direct reprogramming of stem cell properties in colon cancer cells by CD44. EMBO J 30:3186-3199
    • (2011) EMBO J , vol.30 , pp. 3186-3199
    • Su, Y.J.1    Lai, H.M.2    Chang, Y.W.3    Chen, G.Y.4    Lee, J.L.5
  • 10
    • 84858077204 scopus 로고    scopus 로고
    • Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance
    • 10.1186/1471-2407-12-48 22284662 10.1186/1471-2407-12-48
    • López J, Poitevin A, Mendoza-Martínez V, Pérez-Plasencia C, García-Carrancá A (2012) Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance. BMC Cancer 12:48. doi: 10.1186/1471-2407-12-48
    • (2012) BMC Cancer , vol.12 , pp. 48
    • López, J.1    Poitevin, A.2    Mendoza-Martínez, V.3    Pérez-Plasencia, C.4    García-Carrancá, A.5
  • 11
    • 80054998123 scopus 로고    scopus 로고
    • Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway
    • 22032476 10.1186/1756-9966-30-103
    • Xu W, Lin H, Zhang Y, Chen X, Hua B, Hou W, Qi X, Pei Y, Zhu X, Zhao Z, Yang L (2011) Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway. J Exp Clin Cancer Res 30:103
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 103
    • Xu, W.1    Lin, H.2    Zhang, Y.3    Chen, X.4    Hua, B.5    Hou, W.6    Qi, X.7    Pei, Y.8    Zhu, X.9    Zhao, Z.10    Yang, L.11
  • 12
    • 0030774049 scopus 로고    scopus 로고
    • Bioactive constituents of Morus australis and Broussonetia papyrifera
    • 9358644 10.1021/np970186o 1:CAS:528:DyaK2sXmtlegsbs%3D
    • Ko HH, Yu SM, Ko FN, Teng CM, Lin CN (1997) Bioactive constituents of Morus australis and Broussonetia papyrifera. J Nat Prod 60:1008-1011
    • (1997) J Nat Prod , vol.60 , pp. 1008-1011
    • Ko, H.H.1    Yu, S.M.2    Ko, F.N.3    Teng, C.M.4    Lin, C.N.5
  • 13
    • 0032815217 scopus 로고    scopus 로고
    • Chemistry and biological activities of constituents from Morus australis
    • 10434047 10.1016/S0304-4165(99)00084-7 1:CAS:528:DyaK1MXmtVSqu74%3D
    • Ko HH, Wang JJ, Lin HC, Wang JP, Lin CN (1999) Chemistry and biological activities of constituents from Morus australis. Biochim Biophys Acta 1428:293-299
    • (1999) Biochim Biophys Acta , vol.1428 , pp. 293-299
    • Ko, H.H.1    Wang, J.J.2    Lin, H.C.3    Wang, J.P.4    Lin, C.N.5
  • 14
    • 10844277473 scopus 로고    scopus 로고
    • Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai
    • 15636183 10.1016/j.phymed.2003.09.005 1:CAS:528:DC%2BD2MXht12rt7o%3D
    • Sohn HY, Son KH, Kwon CS, Kwon GS, Kang SS (2004) Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis Nakai. Phytomedicine 11:666-672
    • (2004) Phytomedicine , vol.11 , pp. 666-672
    • Sohn, H.Y.1    Son, K.H.2    Kwon, C.S.3    Kwon, G.S.4    Kang, S.S.5
  • 15
    • 46549090195 scopus 로고    scopus 로고
    • Morusin induces apoptosis and suppresses NF-κB activity in human colorectal cancer HT-29 cells
    • 18485277 10.1016/j.bbrc.2008.05.023 1:CAS:528:DC%2BD1cXmvFekur8%3D
    • Lee JC, Won SJ, Chao CL, Wu FL, Liu HS, Ling P, Lin CN, Su CL (2008) Morusin induces apoptosis and suppresses NF-κB activity in human colorectal cancer HT-29 cells. Biochem Biophys Res Commun 372:236-242
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 236-242
    • Lee, J.C.1    Won, S.J.2    Chao, C.L.3    Wu, F.L.4    Liu, H.S.5    Ling, P.6    Lin, C.N.7    Su, C.L.8
  • 17
    • 84862897751 scopus 로고    scopus 로고
    • Expression of BCL10 in cervical cancer has a role in the regulation of cell growth through the activation of NF-κB-dependent cyclin D1 signaling
    • 22564715 10.1016/j.ygyno.2012.04.047 1:CAS:528:DC%2BC38Xns12qsbk%3D
    • Kuo SH, Chou CH, Cheng AL, Wang CW, Chen YH, Chen RJ (2012) Expression of BCL10 in cervical cancer has a role in the regulation of cell growth through the activation of NF-κB-dependent cyclin D1 signaling. Gynecol Oncol 126:245-251
    • (2012) Gynecol Oncol , vol.126 , pp. 245-251
    • Kuo, S.H.1    Chou, C.H.2    Cheng, A.L.3    Wang, C.W.4    Chen, Y.H.5    Chen, R.J.6
  • 18
    • 84872529696 scopus 로고    scopus 로고
    • Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
    • 23277563 10.1073/pnas.1221055110 1:CAS:528:DC%2BC3sXhs1yhtr8%3D
    • Hirsch HA, Iliopoulos D, Struhl K (2013) Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proc Natl Acad Sci U S A 110:972-977
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 972-977
    • Hirsch, H.A.1    Iliopoulos, D.2    Struhl, K.3
  • 19
    • 81155130805 scopus 로고    scopus 로고
    • Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability
    • 21904396 10.1038/cgt.2011.58 1:CAS:528:DC%2BC3MXhtFCnt7rF
    • Gu W, Yeo E, McMillan N, Yu C (2011) Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability. Cancer Gene Ther 18:897-905
    • (2011) Cancer Gene Ther , vol.18 , pp. 897-905
    • Gu, W.1    Yeo, E.2    McMillan, N.3    Yu, C.4
  • 20
    • 84863172251 scopus 로고    scopus 로고
    • Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties
    • 22359637 10.1371/journal.pone.0031864 1:CAS:528:DC%2BC38XjtFWjtb8%3D
    • Chen SF, Chang YC, Nieh S, Yang CY, Lin YS (2012) Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties. PLoS ONE 7:e31864
    • (2012) PLoS ONE , vol.7 , pp. 31864
    • Chen, S.F.1    Chang, Y.C.2    Nieh, S.3    Yang, C.Y.4    Lin, Y.S.5
  • 21
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • 15994920 10.1158/0008-5472.CAN-05-0626 1:CAS:528:DC%2BD2MXlslOqsrw%3D
    • Ponti D, Costa A, Zaffaroni N, Pratesi G, Petrangolini G, Coradini D, Pilotti S, Pierotti MA, Daidone MG (2005) Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res 65:5506-5511
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3    Pratesi, G.4    Petrangolini, G.5    Coradini, D.6    Pilotti, S.7    Pierotti, M.A.8    Daidone, M.G.9
  • 22
    • 77956857331 scopus 로고    scopus 로고
    • Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs
    • 20581442 10.4161/cc.9.14.12371 1:CAS:528:DC%2BC3cXhsFCntL%2FM
    • Cioce M, Gherardi S, Viglietto G, Strano S, Blandino G, Muti P, Ciliberto G (2010) Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs. Cell Cycle 9(14):2878-2887
    • (2010) Cell Cycle , vol.9 , Issue.14 , pp. 2878-2887
    • Cioce, M.1    Gherardi, S.2    Viglietto, G.3    Strano, S.4    Blandino, G.5    Muti, P.6    Ciliberto, G.7
  • 23
    • 84934444135 scopus 로고    scopus 로고
    • Cell sensitivity assays: The MTT assay
    • 21516412 10.1007/978-1-61779-080-5-20
    • van Meerloo J, Kaspers GJ, Cloos J (2011) Cell sensitivity assays: the MTT assay. Methods Mol Biol 731:237-245
    • (2011) Methods Mol Biol , vol.731 , pp. 237-245
    • Van Meerloo, J.1    Kaspers, G.J.2    Cloos, J.3
  • 24
    • 33645957087 scopus 로고    scopus 로고
    • Apoptotic effect of red wine polyphenols on human colon cancer SNU-C4 cells
    • 16243419 10.1016/j.fct.2005.08.031 1:CAS:528:DC%2BD28Xjs1aiurg%3D
    • Kim MJ, Kim YJ, Park HJ, Chung JH, Leem KH, Kim HK (2006) Apoptotic effect of red wine polyphenols on human colon cancer SNU-C4 cells. Food Chem Toxicol 44:898-902
    • (2006) Food Chem Toxicol , vol.44 , pp. 898-902
    • Kim, M.J.1    Kim, Y.J.2    Park, H.J.3    Chung, J.H.4    Leem, K.H.5    Kim, H.K.6
  • 25
    • 84868200946 scopus 로고    scopus 로고
    • Cell cycle arrest and cell apoptosis induced by Equisetum hyemale extract in murine leukemia L1210 cells
    • 23000169 10.1016/j.jep.2012.09.015
    • Li H, Wang P, Liu Q, Cheng X, Zhou Y, Xiao Y (2012) Cell cycle arrest and cell apoptosis induced by Equisetum hyemale extract in murine leukemia L1210 cells. J Ethnopharmacol 144:322-327
    • (2012) J Ethnopharmacol , vol.144 , pp. 322-327
    • Li, H.1    Wang, P.2    Liu, Q.3    Cheng, X.4    Zhou, Y.5    Xiao, Y.6
  • 26
    • 0028625746 scopus 로고
    • A rapid and simple method for the isolation of apoptotic DNA fragments
    • 7816645 10.1093/nar/22.24.5506 1:CAS:528:DyaK2MXivFKls7c%3D
    • Herrmann M, Lorenz HM, Voll R, Grünke M, Woith W, Kalden JR (1994) A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res 22:5506-5507
    • (1994) Nucleic Acids Res , vol.22 , pp. 5506-5507
    • Herrmann, M.1    Lorenz, H.M.2    Voll, R.3    Grünke, M.4    Woith, W.5    Kalden, J.R.6
  • 27
    • 72449210651 scopus 로고    scopus 로고
    • Cancer stem cells: Cell culture, markers, and targets for new therapies
    • 10.1002/jcb.22350
    • Gilbert CA, Ross AH (2009) Cancer stem cells: cell culture, markers, and targets for new therapies. J Cell Biochem 1:1031-1038
    • (2009) J Cell Biochem , vol.1 , pp. 1031-1038
    • Gilbert, C.A.1    Ross, A.H.2
  • 28
    • 84872293839 scopus 로고    scopus 로고
    • Targeting cancer stem cells: A new therapy to cure cancer patients
    • 22679565
    • Hu Y, Fu L (2012) Targeting cancer stem cells: a new therapy to cure cancer patients. Am J Cancer Res 2:340-356
    • (2012) Am J Cancer Res , vol.2 , pp. 340-356
    • Hu, Y.1    Fu, L.2
  • 29
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells -perspectives on current status and future directions: AACR Workshop on cancer stem cells
    • 16990346 10.1158/0008-5472.CAN-06-3126 1:CAS:528:DC%2BD28XhtVamsr3I
    • Clarke MF, Dick JE, Dirks PB, Eaves CJ, Jamieson CH (2006) Cancer stem cells -perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res 66:9339-9344
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.5
  • 31
    • 84861193535 scopus 로고    scopus 로고
    • MicroRNA-199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer-initiating cells
    • 22498306 10.1111/j.1742-4658.2012.08589.x 1:CAS:528:DC%2BC38Xpt1equr0%3D
    • Cheng W, Liu T, Wan X, Gao Y, Wang H (2012) MicroRNA-199a targets CD44 to suppress the tumorigenicity and multidrug resistance of ovarian cancer-initiating cells. FEBS J 279:2047-2059
    • (2012) FEBS J , vol.279 , pp. 2047-2059
    • Cheng, W.1    Liu, T.2    Wan, X.3    Gao, Y.4    Wang, H.5
  • 32
    • 84878428158 scopus 로고    scopus 로고
    • On the origin and destination of cancer stem cells: A conceptual evaluation
    • 23359140
    • van de Stolpe A (2013) On the origin and destination of cancer stem cells: a conceptual evaluation. Am J Cancer Res 3:107-116
    • (2013) Am J Cancer Res , vol.3 , pp. 107-116
    • Van De Stolpe, A.1
  • 33
    • 84863172251 scopus 로고    scopus 로고
    • Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties
    • 22359637 10.1371/journal.pone.0031864 1:CAS:528:DC%2BC38XjtFWjtb8%3D
    • Chen SF, Chang YC, Nieh S, Liu CL, Yang CY, Lin YS (2012) Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties. PLoS ONE 7:e31864
    • (2012) PLoS ONE , vol.7 , pp. 31864
    • Chen, S.F.1    Chang, Y.C.2    Nieh, S.3    Liu, C.L.4    Yang, C.Y.5    Lin, Y.S.6
  • 34
    • 84856089677 scopus 로고    scopus 로고
    • In vitro models
    • 22076915 10.1002/stem.774 1:CAS:528:DC%2BC38Xjs1Sitbg%3D
    • Mather JP (2012) In vitro models. Stem Cells 30:95-99
    • (2012) Stem Cells , vol.30 , pp. 95-99
    • Mather, J.P.1
  • 35
    • 84861831850 scopus 로고    scopus 로고
    • Methods for cancer stem cell detection and isolation
    • 22610581 10.1007/978-1-61779-815-3-32 1:CAS:528:DC%2BC38XhslWis7jM
    • Tirino V, Desiderio V, Paino F, Papaccio G, De Rosa M (2012) Methods for cancer stem cell detection and isolation. Methods Mol Biol 879:513-529
    • (2012) Methods Mol Biol , vol.879 , pp. 513-529
    • Tirino, V.1    Desiderio, V.2    Paino, F.3    Papaccio, G.4    De Rosa, M.5
  • 36
    • 79955492438 scopus 로고    scopus 로고
    • Activation of β-catenin and Akt pathways by twist are critical for the maintenance of EMT associated cancer stem cell-like characters
    • 21284870 10.1186/1471-2407-11-49
    • Li JL, Zhou BH (2011) Activation of β-catenin and Akt pathways by twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer 11:49
    • (2011) BMC Cancer , vol.11 , pp. 49
    • Li, J.L.1    Zhou, B.H.2
  • 37
    • 72449210651 scopus 로고    scopus 로고
    • Cancer stem cells: Cell culture, markers, and targets for new therapies
    • 10.1002/jcb.22350
    • Gilbert CA, Ross AH (2009) Cancer stem cells: cell culture, markers, and targets for new therapies. J Cell Biochem 1:1031-1038
    • (2009) J Cell Biochem , vol.1 , pp. 1031-1038
    • Gilbert, C.A.1    Ross, A.H.2
  • 38
    • 84874400094 scopus 로고    scopus 로고
    • The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure
    • 1:CAS:528:DC%2BC3sXmsVOitLY%3D
    • Chinn SB, Darr OA, Peters RD, Prince ME (2012) The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure. Front Endocrinol (Lausanne) 3:90
    • (2012) Front Endocrinol (Lausanne) , vol.3 , pp. 90
    • Chinn, S.B.1    Darr, O.A.2    Peters, R.D.3    Prince, M.E.4
  • 39
    • 84865109716 scopus 로고    scopus 로고
    • Isolation and characterization of cancer stem cells from cervical cancer HeLa cells
    • 22431223 10.1007/s10616-012-9436-3 1:CAS:528:DC%2BC38XhtVGhtLnJ
    • Zhang SL, Wang YS, Zhou T, Yu XW, Wei ZT, Li YL (2012) Isolation and characterization of cancer stem cells from cervical cancer HeLa cells. Cytotechnology 64:477-484
    • (2012) Cytotechnology , vol.64 , pp. 477-484
    • Zhang, S.L.1    Wang, Y.S.2    Zhou, T.3    Yu, X.W.4    Wei, Z.T.5    Li, Y.L.6
  • 40
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: From innocent bystander to major culprit
    • 12001991 10.1038/nrc780 1:CAS:528:DC%2BD38XivFGqt7k%3D
    • Karin M, Cao Y, Greten FR, Li ZW (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2:301-310
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 41
    • 2642519663 scopus 로고    scopus 로고
    • Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation
    • 15044484 10.1074/jbc.M402305200 1:CAS:528:DC%2BD2cXksV2is74%3D
    • Lin MT, Chang CC, Chen ST, Chang HL, Su JL, Chau YP, Kuo ML (2004) Cyr61 expression confers resistance to apoptosis in breast cancer MCF-7 cells by a mechanism of NF-kappaB-dependent XIAP up-regulation. J Biol Chem 279:24015-24023
    • (2004) J Biol Chem , vol.279 , pp. 24015-24023
    • Lin, M.T.1    Chang, C.C.2    Chen, S.T.3    Chang, H.L.4    Su, J.L.5    Chau, Y.P.6    Kuo, M.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.