Morusin inhibits glioblastoma stem cell growth in vitro and in vivo through stemness attenuation, adipocyte transdifferentiation, and apoptosis induction

Molecular Carcinogenesis

Volumn 55, Issue 1, 2016, Pages 77-89

  Guo, Huijie ^a,b   Liu, Chuanlan ^a   Yang, Liuqi ^a   Dong, Lihua ^a   Wang, Li ^a   Wang, Qiaoping ^a   Li, Haiyan ^a   Zhang, Jie ^a   Lin, Ping ^a   Wang, Xiujie ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

Author keywords

Adipocyte transdifferentiation; Apoptosis; Cancer stem cells; Glioblastoma multiforme; Growth inhibition; Morusin

Indexed keywords

CD133 ANTIGEN; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; TOLONIUM CHLORIDE; TRANSCRIPTION FACTOR SOX2; BIOLOGICAL MARKER; FLAVONOID; MORUSIN;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CANCER TISSUE; CARCINOGENICITY; CELL GROWTH; CELL TRANSDIFFERENTIATION; CELLULAR PARAMETERS; CONTROLLED STUDY; GLIOBLASTOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEMNESS ATTENUATION; WESTERN BLOTTING; ANIMAL; CELL SELF-RENEWAL; DISEASE MODEL; DNA FRAGMENTATION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; TUMOR CELL CULTURE; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; APOPTOSIS; BIOMARKERS; CELL LINE, TUMOR; CELL SELF RENEWAL; CELL TRANSDIFFERENTIATION; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; FLAVONOIDS; GENE EXPRESSION; GLIOBLASTOMA; HUMANS; MICE; NEOPLASTIC STEM CELLS; SPHEROIDS, CELLULAR; TUMOR BURDEN; TUMOR CELLS, CULTURED;

EID: 84954211715     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22260     Document Type: Article

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