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Volumn 245, Issue , 2017, Pages 1645-1654

Metabolic engineering of yeast for fermentative production of flavonoids

Author keywords

Fisetin; Flavonoids; Kaempferol; Resokaempferol; Saccharomyces cerevisiae

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; METABOLIC ENGINEERING; PHENOLS; YEAST;

EID: 85020758611     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2017.06.043     Document Type: Article
Times cited : (149)

References (49)
  • 1
    • 79551478567 scopus 로고    scopus 로고
    • Diversion of flux toward sesquiterpene production in Saccharomyces cerevisiae by fusion of host and heterologous enzymes
    • Albertsen, L., Chen, Y., Bach, L.S., Rattleff, S., Maury, J., Brix, S., Nielsen, J., Mortensen, U.H., Diversion of flux toward sesquiterpene production in Saccharomyces cerevisiae by fusion of host and heterologous enzymes. Appl. Environ. Microbiol. 77 (2011), 1033–1040, 10.1128/AEM.01361-10.
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 1033-1040
    • Albertsen, L.1    Chen, Y.2    Bach, L.S.3    Rattleff, S.4    Maury, J.5    Brix, S.6    Nielsen, J.7    Mortensen, U.H.8
  • 2
    • 84877256074 scopus 로고    scopus 로고
    • Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols
    • Avalos, J.L., Fink, G.R., Stephanopoulos, G., Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat. Biotechnol. 31 (2013), 335–341, 10.1038/nbt.2509.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 335-341
    • Avalos, J.L.1    Fink, G.R.2    Stephanopoulos, G.3
  • 3
    • 84899950682 scopus 로고    scopus 로고
    • Ratio of intracellular precursors concentration and their flux influences hyaluronic acid molecular weight in Streptococcus zooepidemicus and recombinant Lactococcus lactis
    • Badle, S.S., Jayaraman, G., Ramachandran, K.B., Ratio of intracellular precursors concentration and their flux influences hyaluronic acid molecular weight in Streptococcus zooepidemicus and recombinant Lactococcus lactis. Bioresour. Technol. 163 (2014), 222–227, 10.1016/j.biortech.2014.04.027.
    • (2014) Bioresour. Technol. , vol.163 , pp. 222-227
    • Badle, S.S.1    Jayaraman, G.2    Ramachandran, K.B.3
  • 4
    • 84856185031 scopus 로고    scopus 로고
    • The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals
    • Bulzomi, P., Galluzzo, P., Bolli, A., Leone, S., Acconcia, F., Marino, M., The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals. J. Cell. Physiol. 227 (2012), 1891–1898, 10.1002/jcp.22917.
    • (2012) J. Cell. Physiol. , vol.227 , pp. 1891-1898
    • Bulzomi, P.1    Galluzzo, P.2    Bolli, A.3    Leone, S.4    Acconcia, F.5    Marino, M.6
  • 6
    • 84874002570 scopus 로고    scopus 로고
    • A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention
    • Chen, A.Y., Chen, Y.C., A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention. Food Chem. 138 (2013), 2099–2107, 10.1016/j.foodchem.2012.11.139.
    • (2013) Food Chem. , vol.138 , pp. 2099-2107
    • Chen, A.Y.1    Chen, Y.C.2
  • 7
    • 84856117738 scopus 로고    scopus 로고
    • Liquiritigenin isolated from Glycyrrhiza uralensis stimulates osteoblast function in osteoblastic MC3T3-E1 cells
    • Choi, E.M., Liquiritigenin isolated from Glycyrrhiza uralensis stimulates osteoblast function in osteoblastic MC3T3-E1 cells. Int. Immunopharmacol. 12 (2012), 139–143, 10.1016/j.intimp.2011.11.003.
    • (2012) Int. Immunopharmacol. , vol.12 , pp. 139-143
    • Choi, E.M.1
  • 8
    • 84881103854 scopus 로고    scopus 로고
    • Fisetin inhibits migration and invasion of human cervical cancer cells by down-regulating urokinase plasminogen activator expression through suppressing the p38 MAPK-dependent NF-KB signaling pathway
    • Chou, R.H., Hsieh, S.C., Yu, Y.L., Huang, M.H., Huang, Y.C., Hsieh, Y.H., Fisetin inhibits migration and invasion of human cervical cancer cells by down-regulating urokinase plasminogen activator expression through suppressing the p38 MAPK-dependent NF-KB signaling pathway. PLoS One 8 (2013), 1–12, 10.1371/journal.pone.0071983.
    • (2013) PLoS One , vol.8 , pp. 1-12
    • Chou, R.H.1    Hsieh, S.C.2    Yu, Y.L.3    Huang, M.H.4    Huang, Y.C.5    Hsieh, Y.H.6
  • 9
    • 0642306123 scopus 로고    scopus 로고
    • Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery
    • Crozier, A., Lean, M.E.J., McDonald, M.S., Black, C., Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery. J. Agric. Food Chem. 45 (1997), 590–595, 10.1021/jf960339y.
    • (1997) J. Agric. Food Chem. , vol.45 , pp. 590-595
    • Crozier, A.1    Lean, M.E.J.2    McDonald, M.S.3    Black, C.4
  • 10
    • 84895780810 scopus 로고    scopus 로고
    • Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice
    • Currais, A., Prior, M., Dargusch, R., Armando, A., Ehren, J., Schubert, D., Quehenberger, O., Maher, P., Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice. Aging Cell 13 (2014), 379–390, 10.1111/acel.12185.
    • (2014) Aging Cell , vol.13 , pp. 379-390
    • Currais, A.1    Prior, M.2    Dargusch, R.3    Armando, A.4    Ehren, J.5    Schubert, D.6    Quehenberger, O.7    Maher, P.8
  • 11
    • 79959690712 scopus 로고    scopus 로고
    • Recent advances in understanding the antibacterial properties of flavonoids
    • Cushnie, T.P.T., Lamb, A.J., Recent advances in understanding the antibacterial properties of flavonoids. Int. J. Antimicrob. Agents 38 (2011), 99–107, 10.1016/j.ijantimicag.2011.02.014.
    • (2011) Int. J. Antimicrob. Agents , vol.38 , pp. 99-107
    • Cushnie, T.P.T.1    Lamb, A.J.2
  • 12
    • 78651473503 scopus 로고    scopus 로고
    • Effect of varying feedstock – pretreatment chemistry combinations on the formation and accumulation of potentially inhibitory degradation products in biomass hydrolysates
    • Du, B., Sharma, L.N., Becker, C., Chen, S., Mowery, R.A., Van Walsum, G.P., Chambliss, C.K., Effect of varying feedstock – pretreatment chemistry combinations on the formation and accumulation of potentially inhibitory degradation products in biomass hydrolysates. Biotechnol. Bioeng., 2010, 10.1002/bit.22829.
    • (2010) Biotechnol. Bioeng.
    • Du, B.1    Sharma, L.N.2    Becker, C.3    Chen, S.4    Mowery, R.A.5    Van Walsum, G.P.6    Chambliss, C.K.7
  • 14
    • 0036270543 scopus 로고    scopus 로고
    • Transformation of yeast by lithium acetate/single-stranded carrier dna/polyethylene glycol method
    • Gietz, B.R.D., Woods, R.A., Transformation of yeast by lithium acetate/single-stranded carrier dna/polyethylene glycol method. Methods Enzymol. 350 (2002), 87–96.
    • (2002) Methods Enzymol. , vol.350 , pp. 87-96
    • Gietz, B.R.D.1    Woods, R.A.2
  • 15
    • 84920093205 scopus 로고    scopus 로고
    • The Science of Flavonoids
    • Springer Science Business Media Inc New York
    • Grotewold, E., The Science of Flavonoids. 2006, Springer Science Business Media Inc, New York.
    • (2006)
    • Grotewold, E.1
  • 16
    • 34548562078 scopus 로고    scopus 로고
    • Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages
    • Hämäläinen, M., Nieminen, R., Vuorela, P., Heinonen, M., Moilanen, E., Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediators Inflamm., 2007, 10.1155/2007/45673.
    • (2007) Mediators Inflamm.
    • Hämäläinen, M.1    Nieminen, R.2    Vuorela, P.3    Heinonen, M.4    Moilanen, E.5
  • 17
    • 33751391867 scopus 로고
    • Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands
    • Hertog, M.G., Hollman, P.C., Katan, M.B., Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands. J. Agric. Food Chem. 40 (1992), 2379–2383, 10.1021/jf00024a011.
    • (1992) J. Agric. Food Chem. , vol.40 , pp. 2379-2383
    • Hertog, M.G.1    Hollman, P.C.2    Katan, M.B.3
  • 18
    • 84965087526 scopus 로고    scopus 로고
    • Hydrolytic effects of scaffolding proteins CbpB and CbpC on crystalline cellulose mediated by the major cellulolytic complex from Clostridium cellulovorans
    • Jeon, S.D., Kim, S.J., Park, S.H., Choi, G.W., Han, S.O., Hydrolytic effects of scaffolding proteins CbpB and CbpC on crystalline cellulose mediated by the major cellulolytic complex from Clostridium cellulovorans. Bioresour. Technol. 191 (2015), 505–511, 10.1016/j.biortech.2015.02.071.
    • (2015) Bioresour. Technol. , vol.191 , pp. 505-511
    • Jeon, S.D.1    Kim, S.J.2    Park, S.H.3    Choi, G.W.4    Han, S.O.5
  • 20
    • 33644816925 scopus 로고    scopus 로고
    • Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli
    • Leonard, E., Yan, Y., Koffas, M.A.G., Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plant-specific hydroxylated flavonols in Escherichia coli. Metab. Eng. 8 (2006), 172–181, 10.1016/j.ymben.2005.11.001.
    • (2006) Metab. Eng. , vol.8 , pp. 172-181
    • Leonard, E.1    Yan, Y.2    Koffas, M.A.G.3
  • 21
    • 84941962714 scopus 로고    scopus 로고
    • De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae
    • Li, M., Kildegaard, K.R., Chen, Y., Rodriguez, A., Borodina, I., Nielsen, J., De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae. Metab. Eng. 32 (2015), 1–11, 10.1016/j.ymben.2015.08.007.
    • (2015) Metab. Eng. , vol.32 , pp. 1-11
    • Li, M.1    Kildegaard, K.R.2    Chen, Y.3    Rodriguez, A.4    Borodina, I.5    Nielsen, J.6
  • 22
    • 84994894996 scopus 로고    scopus 로고
    • Engineering yeast for high-level production of stilbenoid antioxidants
    • 6:36827
    • Li, M., Schneider, K., Kristensen, M., Borodina, I., Nielsen, J., Engineering yeast for high-level production of stilbenoid antioxidants. Sci. Rep., 2016, 10.1038/srep36827 6:36827.
    • (2016) Sci. Rep.
    • Li, M.1    Schneider, K.2    Kristensen, M.3    Borodina, I.4    Nielsen, J.5
  • 23
    • 84862995991 scopus 로고    scopus 로고
    • Liquiritigenin inhibits tumor growth and vascularization in a mouse model of HeLa cells
    • Liu, Y., Xie, S., Wang, Y., Luo, K., Wang, Y., Cai, Y., Liquiritigenin inhibits tumor growth and vascularization in a mouse model of HeLa cells. Molecules 17 (2012), 7206–7216, 10.3390/molecules17067206.
    • (2012) Molecules , vol.17 , pp. 7206-7216
    • Liu, Y.1    Xie, S.2    Wang, Y.3    Luo, K.4    Wang, Y.5    Cai, Y.6
  • 24
    • 84866167520 scopus 로고    scopus 로고
    • Optimization of extraction of phenolic acids from a vegetable waste product using a pressurized liquid extractor
    • Luthria, D.L., Optimization of extraction of phenolic acids from a vegetable waste product using a pressurized liquid extractor. J. Funct. Foods 4 (2012), 842–850, 10.1016/j.jff.2012.06.001.
    • (2012) J. Funct. Foods , vol.4 , pp. 842-850
    • Luthria, D.L.1
  • 25
    • 78650525484 scopus 로고    scopus 로고
    • Erk activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease
    • Maher, P., Dargusch, R., Bodai, L., Gerard, P.E., Purcell, J.M., Lawrence Marsh, J., Erk activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease. Hum. Mol. Genet. 20 (2011), 261–270, 10.1093/hmg/ddq460.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 261-270
    • Maher, P.1    Dargusch, R.2    Bodai, L.3    Gerard, P.E.4    Purcell, J.M.5    Lawrence Marsh, J.6
  • 26
    • 34247152943 scopus 로고    scopus 로고
    • Recovery of antioxidant phenolics from white vinification solid by-products employing water/ethanol mixtures
    • Makris, D.P., Boskou, G., Andrikopoulos, N.K., Recovery of antioxidant phenolics from white vinification solid by-products employing water/ethanol mixtures. Bioresour. Technol. 98 (2007), 2963–2967, 10.1016/j.biortech.2006.10.003.
    • (2007) Bioresour. Technol. , vol.98 , pp. 2963-2967
    • Makris, D.P.1    Boskou, G.2    Andrikopoulos, N.K.3
  • 27
    • 84977943138 scopus 로고    scopus 로고
    • Opportunity for high value-added chemicals from food supply chain wastes
    • Matharu, A.S., De Melo, E.M., Houghton, J.A., Opportunity for high value-added chemicals from food supply chain wastes. Bioresour. Technol. 215 (2016), 123–130, 10.1016/j.biortech.2016.03.039.
    • (2016) Bioresour. Technol. , vol.215 , pp. 123-130
    • Matharu, A.S.1    De Melo, E.M.2    Houghton, J.A.3
  • 28
    • 0034851475 scopus 로고    scopus 로고
    • Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
    • Miean, K.H., Mohamed, S., Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem. 49 (2001), 3106–3112.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 3106-3112
    • Miean, K.H.1    Mohamed, S.2
  • 29
    • 84857995434 scopus 로고    scopus 로고
    • Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform
    • Mikkelsen, M.D., Buron, L.D., Salomonsen, B., Olsen, C.E., Hansen, B.G., Mortensen, U.H., Halkier, B.A., Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform. Metab. Eng. 14:2 (2012), 104–111, 10.1016/j.ymben.2012.01.006.
    • (2012) Metab. Eng. , vol.14 , Issue.2 , pp. 104-111
    • Mikkelsen, M.D.1    Buron, L.D.2    Salomonsen, B.3    Olsen, C.E.4    Hansen, B.G.5    Mortensen, U.H.6    Halkier, B.A.7
  • 30
    • 84893813494 scopus 로고    scopus 로고
    • Current options for the valorization of food manufacturing waste: a review
    • Mirabella, N., Castellani, V., Sala, S., Current options for the valorization of food manufacturing waste: a review. J. Clean. Prod. 65 (2014), 28–41, 10.1016/j.jclepro.2013.10.051.
    • (2014) J. Clean. Prod. , vol.65 , pp. 28-41
    • Mirabella, N.1    Castellani, V.2    Sala, S.3
  • 31
    • 84879172594 scopus 로고    scopus 로고
    • Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues
    • Mora-pale, M., Sanchez-rodriguez, S.P., Linhardt, R.J., Dordick, J.S., Koffas, M.A.G., Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues. Plant Sci. 210 (2013), 10–24, 10.1016/j.plantsci.2013.05.005.
    • (2013) Plant Sci. , vol.210 , pp. 10-24
    • Mora-pale, M.1    Sanchez-rodriguez, S.P.2    Linhardt, R.J.3    Dordick, J.S.4    Koffas, M.A.G.5
  • 32
    • 84939263422 scopus 로고    scopus 로고
    • Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells
    • Mukhtar, E., Adhami, V.M., Sechi, M., Mukhtar, H., Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells. Cancer Lett. 367 (2015), 173–183, 10.1016/j.canlet.2015.07.030.
    • (2015) Cancer Lett. , vol.367 , pp. 173-183
    • Mukhtar, E.1    Adhami, V.M.2    Sechi, M.3    Mukhtar, H.4
  • 33
    • 0033032915 scopus 로고    scopus 로고
    • The polyphenolic content of fruit and vegetables and their antioxidant activities. What does a serving constitute?
    • Paganga, G., Miller, N., Rice-Evans, C.A., The polyphenolic content of fruit and vegetables and their antioxidant activities. What does a serving constitute?. Free Radical Res. 30 (1999), 153–162, 10.1080/10715769900300161.
    • (1999) Free Radical Res. , vol.30 , pp. 153-162
    • Paganga, G.1    Miller, N.2    Rice-Evans, C.A.3
  • 34
    • 84897450938 scopus 로고    scopus 로고
    • Industrial robust yeast isolates with great potential for fermentation of lignocellulosic biomass
    • Pereira, F.B., Romaní A., Ruiz, H.A., Teixeira, J.A., Domingues, L., Industrial robust yeast isolates with great potential for fermentation of lignocellulosic biomass. Bioresour. Technol. 161 (2014), 192–199, 10.1016/j.biortech.2014.03.043.
    • (2014) Bioresour. Technol. , vol.161 , pp. 192-199
    • Pereira, F.B.1    Romaní, A.2    Ruiz, H.A.3    Teixeira, J.A.4    Domingues, L.5
  • 35
    • 84873287249 scopus 로고    scopus 로고
    • Food waste biomass: a resource for high-value Chemicals
    • Pfaltzgraff, L.A., De, M., Cooper, E.C., Budarin, V., Clark, H., Food waste biomass: a resource for high-value Chemicals. Green. Chem. 15 (2013), 307–314, 10.1039/c2gc36978h.
    • (2013) Green. Chem. , vol.15 , pp. 307-314
    • Pfaltzgraff, L.A.1    De, M.2    Cooper, E.C.3    Budarin, V.4    Clark, H.5
  • 36
    • 84872332879 scopus 로고    scopus 로고
    • Neuroprotective effect of naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke
    • Raza, S.S., Khan, M.M., Ahmad, A., Ashafaq, M., Islam, F., Wagner, A.P., Safhi, M.M., Islam, F., Neuroprotective effect of naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke. Neuroscience 230 (2013), 157–171, 10.1016/j.neuroscience.2012.10.041.
    • (2013) Neuroscience , vol.230 , pp. 157-171
    • Raza, S.S.1    Khan, M.M.2    Ahmad, A.3    Ashafaq, M.4    Islam, F.5    Wagner, A.P.6    Safhi, M.M.7    Islam, F.8
  • 37
    • 84986254065 scopus 로고    scopus 로고
    • Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis
    • Rodriguez, A., Kildegaard, K.R., Li, M., Borodina, I., Nielsen, J., Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis. Metab. Eng. 31 (2015), 181–188, 10.1016/j.ymben.2015.08.003.
    • (2015) Metab. Eng. , vol.31 , pp. 181-188
    • Rodriguez, A.1    Kildegaard, K.R.2    Li, M.3    Borodina, I.4    Nielsen, J.5
  • 38
    • 84856562650 scopus 로고    scopus 로고
    • Microwave-assisted extraction of flavonoids: a review
    • Routray, W., Orsat, V., Microwave-assisted extraction of flavonoids: a review. Food Bioprocess Technol. 5 (2012), 409–424, 10.1007/s11947-011-0573-z.
    • (2012) Food Bioprocess Technol. , vol.5 , pp. 409-424
    • Routray, W.1    Orsat, V.2
  • 39
    • 79958715193 scopus 로고    scopus 로고
    • Optimization of a heterologous pathway for the production of flavonoids from glucose
    • Santos, C.N.S., Koffas, M., Stephanopoulos, G., Optimization of a heterologous pathway for the production of flavonoids from glucose. Metab. Eng. 13 (2011), 392–400, 10.1016/j.ymben.2011.02.002.
    • (2011) Metab. Eng. , vol.13 , pp. 392-400
    • Santos, C.N.S.1    Koffas, M.2    Stephanopoulos, G.3
  • 40
    • 84903976212 scopus 로고    scopus 로고
    • Improving production of malonyl coenzyme A-derived metabolites 5, 1–8. doi:.
    • Shi, S., Chen, Y., Siewers, V., 2014. Improving production of malonyl coenzyme A-derived metabolites 5, 1–8. doi:10.1128/mBio.01130-14.
    • (2014)
    • Shi, S.1    Chen, Y.2    Siewers, V.3
  • 41
    • 84938397207 scopus 로고    scopus 로고
    • Assembly of a novel biosynthetic pathway for production of the plant flavonoid fisetin in Escherichia coli
    • Stahlhut, S.G., Siedler, S., Malla, S., Harrison, S.J., Maury, J., Neves, A.R., Forster, J., Assembly of a novel biosynthetic pathway for production of the plant flavonoid fisetin in Escherichia coli. Metab. Eng. 31 (2015), 84–93, 10.1016/j.ymben.2015.07.002.
    • (2015) Metab. Eng. , vol.31 , pp. 84-93
    • Stahlhut, S.G.1    Siedler, S.2    Malla, S.3    Harrison, S.J.4    Maury, J.5    Neves, A.R.6    Forster, J.7
  • 42
    • 84944275832 scopus 로고    scopus 로고
    • EasyClone 2.0: expanded toolkit of integrative vectors for stable gene expression in industrial Saccharomyces cerevisiae strains
    • Stovicek, V., Borja, G.M., Forster, J., Borodina, I., EasyClone 2.0: expanded toolkit of integrative vectors for stable gene expression in industrial Saccharomyces cerevisiae strains. J. Ind. Microbiol. Biotechnol. 42 (2015), 1519–1531, 10.1007/s10295-015-1684-8.
    • (2015) J. Ind. Microbiol. Biotechnol. , vol.42 , pp. 1519-1531
    • Stovicek, V.1    Borja, G.M.2    Forster, J.3    Borodina, I.4
  • 43
    • 84942279091 scopus 로고    scopus 로고
    • Benchmarking two commonly used Saccharomyces cerevisiae strains for heterologous vanillin-β-glucoside production
    • Strucko, T., Magdenoska, O., Mortensen, U.H., Benchmarking two commonly used Saccharomyces cerevisiae strains for heterologous vanillin-β-glucoside production. Metab. Eng. Commun. 2 (2015), 99–108, 10.1016/j.meteno.2015.09.001.
    • (2015) Metab. Eng. Commun. , vol.2 , pp. 99-108
    • Strucko, T.1    Magdenoska, O.2    Mortensen, U.H.3
  • 44
    • 70449533072 scopus 로고    scopus 로고
    • Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae
    • Trantas, E., Panopoulos, N., Ververidis, F., Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae. Metab. Eng. 11 (2009), 355–366, 10.1016/j.ymben.2009.07.004.
    • (2009) Metab. Eng. , vol.11 , pp. 355-366
    • Trantas, E.1    Panopoulos, N.2    Ververidis, F.3
  • 45
    • 84966746477 scopus 로고    scopus 로고
    • Effect of fermentation parameters, elicitors and precursors on camptothecin production from the endophyte Fusarium solani
    • Venugopalan, A., Potunuru, U.R., Dixit, M., Srivastava, S., Effect of fermentation parameters, elicitors and precursors on camptothecin production from the endophyte Fusarium solani. Bioresour. Technol. 213 (2016), 311–318, 10.1016/j.biortech.2016.05.023.
    • (2016) Bioresour. Technol. , vol.213 , pp. 311-318
    • Venugopalan, A.1    Potunuru, U.R.2    Dixit, M.3    Srivastava, S.4
  • 46
    • 80052644333 scopus 로고    scopus 로고
    • Metabolic engineering of flavonoids in plants and microorganisms
    • Wang, Y., Chen, S., Yu, O., Metabolic engineering of flavonoids in plants and microorganisms. Appl. Microbiol. Biotechnol. 91 (2011), 949–956, 10.1007/s00253-011-3449-2.
    • (2011) Appl. Microbiol. Biotechnol. , vol.91 , pp. 949-956
    • Wang, Y.1    Chen, S.2    Yu, O.3
  • 48
    • 77954518203 scopus 로고    scopus 로고
    • Reseda luteola L. extract displays antiproliferative and pro-apoptotic activities that are related to its major flavonoids
    • Woelfle, U., Simon-Haarhaus, B., Merfort, I., Schempp, C.M., Reseda luteola L. extract displays antiproliferative and pro-apoptotic activities that are related to its major flavonoids. Phytother. Res. 24 (2010), 1033–1036, 10.1002/ptr.3069.
    • (2010) Phytother. Res. , vol.24 , pp. 1033-1036
    • Woelfle, U.1    Simon-Haarhaus, B.2    Merfort, I.3    Schempp, C.M.4


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