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Volumn 6, Issue 8, 2017, Pages 819-832

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

Author keywords

Energy metabolism; NAD+; Nicotinamide riboside; Skeletal muscle

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NICOTINAMIDE RIBOSIDE; NICOTINAMIDE RIBOSIDE KINASE 1; NICOTINAMIDE RIBOSIDE KINASE 2; UNCLASSIFIED DRUG; CYTOKINE; NICOTINAMIDE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, MOUSE; NICOTINAMIDE-BETA-RIBOSIDE; NMRK1 PROTEIN, MOUSE; PHOSPHOTRANSFERASE;

EID: 85020386967     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2017.05.011     Document Type: Article
Times cited : (99)

References (67)
  • 2
    • 50949120914 scopus 로고    scopus 로고
    • Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition
    • Bogan, K.L., Brenner, C., Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. Annual Review of Nutrition 28:1 (2008), 115–130.
    • (2008) Annual Review of Nutrition , vol.28 , Issue.1 , pp. 115-130
    • Bogan, K.L.1    Brenner, C.2
  • 3
    • 84880517634 scopus 로고    scopus 로고
    • The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
    • Mouchiroud, Laurent, Houtkooper, Riekelt H., Moullan, Norman, Katsyuba, Elena, Ryu, Dongryeol, Cantó, Carles, et al. The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell 154:2 (2013), 430–441.
    • (2013) Cell , vol.154 , Issue.2 , pp. 430-441
    • Mouchiroud, L.1    Houtkooper, R.H.2    Moullan, N.3    Katsyuba, E.4    Ryu, D.5    Cantó, C.6
  • 4
    • 69249116960 scopus 로고    scopus 로고
    • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD
    • Amat, R., Planavila, A., Chen, S.L., Iglesias, R., Giralt, M., Villarroya, F., SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. Journal of Biological Chemistry 284:33 (2009), 21872–21880.
    • (2009) Journal of Biological Chemistry , vol.284 , Issue.33 , pp. 21872-21880
    • Amat, R.1    Planavila, A.2    Chen, S.L.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 5
    • 77249156847 scopus 로고    scopus 로고
    • Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
    • Canto, C., Jiang, L.Q., Deshmukh, A.S., Mataki, C., Coste, A., Lagouge, M., et al. Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metabolism 11:3 (2010), 213–219.
    • (2010) Cell Metabolism , vol.11 , Issue.3 , pp. 213-219
    • Canto, C.1    Jiang, L.Q.2    Deshmukh, A.S.3    Mataki, C.4    Coste, A.5    Lagouge, M.6
  • 8
    • 84873378527 scopus 로고    scopus 로고
    • Exercise metabolism and the molecular regulation of skeletal muscle adaptation
    • Egan, B., Zierath, Juleen R., Exercise metabolism and the molecular regulation of skeletal muscle adaptation. Cell Metabolism 17:2 (2013), 162–184.
    • (2013) Cell Metabolism , vol.17 , Issue.2 , pp. 162-184
    • Egan, B.1    Zierath, J.R.2
  • 9
    • 70449212074 scopus 로고
    • Biosynthesis of diphosphopyridine nucleotide: I. Identification of intermediates
    • Preiss, J., Handler, P., Biosynthesis of diphosphopyridine nucleotide: I. Identification of intermediates. Journal of Biological Chemistry 233:2 (1958), 488–492.
    • (1958) Journal of Biological Chemistry , vol.233 , Issue.2 , pp. 488-492
    • Preiss, J.1    Handler, P.2
  • 10
    • 70449213670 scopus 로고
    • Biosynthesis of diphosphopyridine nucleotide: II. Enzymatic aspects
    • Preiss, J., Handler, P., Biosynthesis of diphosphopyridine nucleotide: II. Enzymatic aspects. Journal of Biological Chemistry 233:2 (1958), 493–500.
    • (1958) Journal of Biological Chemistry , vol.233 , Issue.2 , pp. 493-500
    • Preiss, J.1    Handler, P.2
  • 12
    • 2342550554 scopus 로고    scopus 로고
    • Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
    • Bieganowski, P., Brenner, C., Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell 117:4 (2004), 495–502.
    • (2004) Cell , vol.117 , Issue.4 , pp. 495-502
    • Bieganowski, P.1    Brenner, C.2
  • 15
    • 84962030356 scopus 로고    scopus 로고
    • Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans
    • van de Weijer, T., Phielix, E., Bilet, L., Williams, E.G., Ropelle, E.R., Bierwagen, A., et al. Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:4 (2015), 1193–1201.
    • (2015) Diabetes , vol.64 , Issue.4 , pp. 1193-1201
    • van de Weijer, T.1    Phielix, E.2    Bilet, L.3    Williams, E.G.4    Ropelle, E.R.5    Bierwagen, A.6
  • 16
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • Revollo, J.R., Grimm, A.A., Imai, S.-i., The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. Journal of Biological Chemistry 279:49 (2004), 50754–50763.
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.49 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.-I.3
  • 17
    • 84875727264 scopus 로고    scopus 로고
    • SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging
    • Zarzuelo, M.J., López-Sepúlveda, R., Sánchez, M., Romero, M., Gómez-Guzmán, M., Ungvary, Z., et al. SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging. Biochemical Pharmacology 85:9 (2013), 1288–1296.
    • (2013) Biochemical Pharmacology , vol.85 , Issue.9 , pp. 1288-1296
    • Zarzuelo, M.J.1    López-Sepúlveda, R.2    Sánchez, M.3    Romero, M.4    Gómez-Guzmán, M.5    Ungvary, Z.6
  • 18
    • 84861697885 scopus 로고    scopus 로고
    • Niacin: chemical forms, bioavailability, and health effects
    • MacKay, D., Hathcock, J., Guarneri, E., Niacin: chemical forms, bioavailability, and health effects. Nutrition Reviews 70:6 (2012), 357–366.
    • (2012) Nutrition Reviews , vol.70 , Issue.6 , pp. 357-366
    • MacKay, D.1    Hathcock, J.2    Guarneri, E.3
  • 19
    • 80053920774 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
    • Yoshino, J., Mills, K.F., Yoon, M.J., Imai, S., Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metabolism 14:4 (2011), 528–536.
    • (2011) Cell Metabolism , vol.14 , Issue.4 , pp. 528-536
    • Yoshino, J.1    Mills, K.F.2    Yoon, M.J.3    Imai, S.4
  • 20
    • 84894143537 scopus 로고    scopus 로고
    • Partial reversal of skeletal muscle aging by restoration of normal NAD(+) levels
    • Mendelsohn, A.R., Larrick, J.W., Partial reversal of skeletal muscle aging by restoration of normal NAD(+) levels. Rejuvenation Research 17:1 (2014), 62–69.
    • (2014) Rejuvenation Research , vol.17 , Issue.1 , pp. 62-69
    • Mendelsohn, A.R.1    Larrick, J.W.2
  • 21
    • 84893442805 scopus 로고    scopus 로고
    • Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
    • Gomes, A.P., Price, N.L., Ling, A.J., Moslehi, J.J., Montgomery, M.K., Rajman, L., et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell 155:7 (2013), 1624–1638.
    • (2013) Cell , vol.155 , Issue.7 , pp. 1624-1638
    • Gomes, A.P.1    Price, N.L.2    Ling, A.J.3    Moslehi, J.J.4    Montgomery, M.K.5    Rajman, L.6
  • 22
    • 84862022077 scopus 로고    scopus 로고
    • The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
    • Cantó, C., Houtkooper Riekelt, H., Pirinen, E., Youn Dou, Y., Oosterveer Maaike, H., Cen, Y., et al. The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metabolism 15:6 (2012), 838–847.
    • (2012) Cell Metabolism , vol.15 , Issue.6 , pp. 838-847
    • Cantó, C.1    Houtkooper Riekelt, H.2    Pirinen, E.3    Youn Dou, Y.4    Oosterveer Maaike, H.5    Cen, Y.6
  • 23
    • 84901848955 scopus 로고    scopus 로고
    • Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
    • Khan, N.A., Auranen, M., Paetau, I., Pirinen, E., Euro, L., Forsstrom, S., et al. Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3. EMBO Molecular Medicine 6:6 (2014), 721–731.
    • (2014) EMBO Molecular Medicine , vol.6 , Issue.6 , pp. 721-731
    • Khan, N.A.1    Auranen, M.2    Paetau, I.3    Pirinen, E.4    Euro, L.5    Forsstrom, S.6
  • 24
    • 85021308770 scopus 로고    scopus 로고
    • Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats
    • Hamity, M.V., White, S.R., Walder, R.Y., Schmidt, M.S., Brenner, C., Hammond, D.L., Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats. Pain 158:5 (2017), 962–972.
    • (2017) Pain , vol.158 , Issue.5 , pp. 962-972
    • Hamity, M.V.1    White, S.R.2    Walder, R.Y.3    Schmidt, M.S.4    Brenner, C.5    Hammond, D.L.6
  • 27
    • 84971286337 scopus 로고    scopus 로고
    • Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk
    • Trammell, S.A., Yu, L., Redpath, P., Migaud, M.E., Brenner, C., Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk. Journal of Nutrition 146:5 (2016), 957–963.
    • (2016) Journal of Nutrition , vol.146 , Issue.5 , pp. 957-963
    • Trammell, S.A.1    Yu, L.2    Redpath, P.3    Migaud, M.E.4    Brenner, C.5
  • 28
    • 84991294515 scopus 로고    scopus 로고
    • NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
    • Ratajczak, J., Joffraud, M., Trammell, S.A., Ras, R., Canela, N., Boutant, M., et al. NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells. Nature Communications, 7, 2016, 13103.
    • (2016) Nature Communications , vol.7 , pp. 13103
    • Ratajczak, J.1    Joffraud, M.2    Trammell, S.A.3    Ras, R.4    Canela, N.5    Boutant, M.6
  • 29
    • 84903300241 scopus 로고    scopus 로고
    • A simplified immunohistochemical classification of skeletal muscle fibres in mouse
    • Kammoun, M., Cassar-Malek, I., Meunier, B., Picard, B., A simplified immunohistochemical classification of skeletal muscle fibres in mouse. European Journal of Histochemistry, 58(2), 2014, 2254.
    • (2014) European Journal of Histochemistry , vol.58 , Issue.2 , pp. 2254
    • Kammoun, M.1    Cassar-Malek, I.2    Meunier, B.3    Picard, B.4
  • 30
    • 84994589040 scopus 로고    scopus 로고
    • A one-step immunostaining method to visualize rodent muscle fiber type within a single specimen
    • Sawano, S., Komiya, Y., Ichitsubo, R., Ohkawa, Y., Nakamura, M., Tatsumi, R., et al. A one-step immunostaining method to visualize rodent muscle fiber type within a single specimen. PLoS One, 11(11), 2016.
    • (2016) PLoS One , vol.11 , Issue.11
    • Sawano, S.1    Komiya, Y.2    Ichitsubo, R.3    Ohkawa, Y.4    Nakamura, M.5    Tatsumi, R.6
  • 31
    • 84859951558 scopus 로고    scopus 로고
    • Rapid determination of myosin heavy chain expression in rat, mouse, and human skeletal muscle using multicolor immunofluorescence analysis
    • Bloemberg, D., Quadrilatero, J., Rapid determination of myosin heavy chain expression in rat, mouse, and human skeletal muscle using multicolor immunofluorescence analysis. PLoS One, 7(4), 2012, e35273.
    • (2012) PLoS One , vol.7 , Issue.4 , pp. e35273
    • Bloemberg, D.1    Quadrilatero, J.2
  • 33
    • 84888626285 scopus 로고    scopus 로고
    • Targeted, LCMS-based metabolomics for quantitative measurement of NAD(+) metabolites
    • Trammell, S.A., Brenner, C., Targeted, LCMS-based metabolomics for quantitative measurement of NAD(+) metabolites. Computational and Structural Biotechnology Journal, 4, 2013, e201301012.
    • (2013) Computational and Structural Biotechnology Journal , vol.4 , pp. e201301012
    • Trammell, S.A.1    Brenner, C.2
  • 34
    • 84912572145 scopus 로고    scopus 로고
    • Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues
    • Mori, V., Amici, A., Mazzola, F., Di Stefano, M., Conforti, L., Magni, G., et al. Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues. PLoS One, 9(11), 2014, e113939.
    • (2014) PLoS One , vol.9 , Issue.11 , pp. e113939
    • Mori, V.1    Amici, A.2    Mazzola, F.3    Di Stefano, M.4    Conforti, L.5    Magni, G.6
  • 35
    • 0027958452 scopus 로고
    • Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor
    • Samal, B., Sun, Y., Stearns, G., Xie, C., Suggs, S., McNiece, I., Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Molecular and Cellular Biology 14:2 (1994), 1431–1437.
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.2 , pp. 1431-1437
    • Samal, B.1    Sun, Y.2    Stearns, G.3    Xie, C.4    Suggs, S.5    McNiece, I.6
  • 36
    • 0037500302 scopus 로고    scopus 로고
    • Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency
    • Hara, N., Yamada, K., Terashima, M., Osago, H., Shimoyama, M., Tsuchiya, M., Molecular identification of human glutamine- and ammonia-dependent NAD synthetases. Carbon-nitrogen hydrolase domain confers glutamine dependency. Journal of Biological Chemistry 278:13 (2003), 10914–10921.
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.13 , pp. 10914-10921
    • Hara, N.1    Yamada, K.2    Terashima, M.3    Osago, H.4    Shimoyama, M.5    Tsuchiya, M.6
  • 37
    • 43749114512 scopus 로고    scopus 로고
    • Deletion of Hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy
    • Lavery, G.G., Walker, E.A., Turan, N., Rogoff, D., Ryder, J.W., Shelton, J.M., et al. Deletion of Hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy. Journal of Biological Chemistry 283:13 (2008), 8453–8461.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.13 , pp. 8453-8461
    • Lavery, G.G.1    Walker, E.A.2    Turan, N.3    Rogoff, D.4    Ryder, J.W.5    Shelton, J.M.6
  • 38
    • 84991088710 scopus 로고    scopus 로고
    • Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle
    • Frederick, D.W., Loro, E., Liu, L., Davila, A. Jr., Chellappa, K., Silverman, I.M., et al. Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle. Cell Metabolism 24:2 (2016), 269–282.
    • (2016) Cell Metabolism , vol.24 , Issue.2 , pp. 269-282
    • Frederick, D.W.1    Loro, E.2    Liu, L.3    Davila, A.4    Chellappa, K.5    Silverman, I.M.6
  • 39
    • 84966441621 scopus 로고    scopus 로고
    • NAMPT regulates mitochondria biogenesis via NAD metabolism and calcium binding proteins during skeletal muscle contraction
    • Kim, J.S., Yoon, C.S., Park, D.R., NAMPT regulates mitochondria biogenesis via NAD metabolism and calcium binding proteins during skeletal muscle contraction. Journal of Exercise Nutrition & Biochemistry 18:3 (2014), 259–266.
    • (2014) Journal of Exercise Nutrition & Biochemistry , vol.18 , Issue.3 , pp. 259-266
    • Kim, J.S.1    Yoon, C.S.2    Park, D.R.3
  • 40
    • 84946771272 scopus 로고    scopus 로고
    • Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells
    • Kulikova, V., Shabalin, K., Nerinovski, K., Dolle, C., Niere, M., Yakimov, A., et al. Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells. Journal of Biological Chemistry 290:45 (2015), 27124–27137.
    • (2015) Journal of Biological Chemistry , vol.290 , Issue.45 , pp. 27124-27137
    • Kulikova, V.1    Shabalin, K.2    Nerinovski, K.3    Dolle, C.4    Niere, M.5    Yakimov, A.6
  • 41
    • 0042377362 scopus 로고    scopus 로고
    • Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase
    • Bieganowski, P., Pace, H.C., Brenner, C., Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase. Journal of Biological Chemistry 278:35 (2003), 33049–33055.
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.35 , pp. 33049-33055
    • Bieganowski, P.1    Pace, H.C.2    Brenner, C.3
  • 42
    • 0242526050 scopus 로고    scopus 로고
    • FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
    • Hasmann, M., Schemainda, I., FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Research 63:21 (2003), 7436–7442.
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7436-7442
    • Hasmann, M.1    Schemainda, I.2
  • 43
    • 43049121395 scopus 로고    scopus 로고
    • Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
    • Fulco, M., Cen, Y., Zhao, P., Hoffman, E.P., McBurney, M.W., Sauve, A.A., et al. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Developmental Cell 14:5 (2008), 661–673.
    • (2008) Developmental Cell , vol.14 , Issue.5 , pp. 661-673
    • Fulco, M.1    Cen, Y.2    Zhao, P.3    Hoffman, E.P.4    McBurney, M.W.5    Sauve, A.A.6
  • 45
    • 58649106456 scopus 로고    scopus 로고
    • Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism
    • Belenky, P., Christensen, K.C., Gazzaniga, F., Pletnev, A.A., Brenner, C., Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism. Journal of Biological Chemistry 284:1 (2009), 158–164.
    • (2009) Journal of Biological Chemistry , vol.284 , Issue.1 , pp. 158-164
    • Belenky, P.1    Christensen, K.C.2    Gazzaniga, F.3    Pletnev, A.A.4    Brenner, C.5
  • 46
    • 0033625383 scopus 로고    scopus 로고
    • BST-1/CD157 regulates the humoral immune responses in vivo
    • Ishihara, K., Hirano, T., BST-1/CD157 regulates the humoral immune responses in vivo. Chemical Immunology 75 (2000), 235–255.
    • (2000) Chemical Immunology , vol.75 , pp. 235-255
    • Ishihara, K.1    Hirano, T.2
  • 47
    • 84988714416 scopus 로고    scopus 로고
    • Head to head comparison of short-term treatment with the NAD(+) precursor nicotinamide mononucleotide (NMN) and 6 weeks of exercise in obese female mice
    • Uddin, G.M., Youngson, N.A., Sinclair, D.A., Morris, M.J., Head to head comparison of short-term treatment with the NAD(+) precursor nicotinamide mononucleotide (NMN) and 6 weeks of exercise in obese female mice. Frontiers in Pharmacology, 7, 2016, 258.
    • (2016) Frontiers in Pharmacology , vol.7 , pp. 258
    • Uddin, G.M.1    Youngson, N.A.2    Sinclair, D.A.3    Morris, M.J.4
  • 48
    • 84960352089 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice
    • de Picciotto, N.E., Gano, L.B., Johnson, L.C., Martens, C.R., Sindler, A.L., Mills, K.F., et al. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. Aging Cell 15:3 (2016), 522–530.
    • (2016) Aging Cell , vol.15 , Issue.3 , pp. 522-530
    • de Picciotto, N.E.1    Gano, L.B.2    Johnson, L.C.3    Martens, C.R.4    Sindler, A.L.5    Mills, K.F.6
  • 49
    • 84965034275 scopus 로고    scopus 로고
    • + repletion improves mitochondrial and stem cell function and enhances life span in mice
    • + repletion improves mitochondrial and stem cell function and enhances life span in mice. Science 352:6292 (2016), 1436–1443.
    • (2016) Science , vol.352 , Issue.6292 , pp. 1436-1443
    • Zhang, H.1    Ryu, D.2    Wu, Y.3    Gariani, K.4    Wang, X.5    Luan, P.6
  • 50
    • 79955591489 scopus 로고    scopus 로고
    • Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in Wistar rats
    • Braidy, N., Guillemin, G.J., Mansour, H., Chan-Ling, T., Poljak, A., Grant, R., Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in Wistar rats. PLoS One, 6(4), 2011, e19194.
    • (2011) PLoS One , vol.6 , Issue.4 , pp. e19194
    • Braidy, N.1    Guillemin, G.J.2    Mansour, H.3    Chan-Ling, T.4    Poljak, A.5    Grant, R.6
  • 52
    • 84877075806 scopus 로고    scopus 로고
    • Protective effect of nicotinamide on high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells is attributed to its inhibitory activity to sirtuins
    • Lee, S.J., Choi, S.E., Jung, I.R., Lee, K.W., Kang, Y., Protective effect of nicotinamide on high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells is attributed to its inhibitory activity to sirtuins. Archives of Biochemistry and Biophysics 535:2 (2013), 187–196.
    • (2013) Archives of Biochemistry and Biophysics , vol.535 , Issue.2 , pp. 187-196
    • Lee, S.J.1    Choi, S.E.2    Jung, I.R.3    Lee, K.W.4    Kang, Y.5
  • 53
    • 84922264188 scopus 로고    scopus 로고
    • Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
    • Frederick, D.W., Davis, J.G., Davila, A. Jr., Agarwal, B., Michan, S., Puchowicz, M.A., et al. Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism. Journal of Biological Chemistry 290:3 (2015), 1546–1558.
    • (2015) Journal of Biological Chemistry , vol.290 , Issue.3 , pp. 1546-1558
    • Frederick, D.W.1    Davis, J.G.2    Davila, A.3    Agarwal, B.4    Michan, S.5    Puchowicz, M.A.6
  • 54
    • 84891506172 scopus 로고    scopus 로고
    • Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation
    • Jing, E., O'Neill, B.T., Rardin, M.J., Kleinridders, A., Ilkeyeva, O.R., Ussar, S., et al. Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. Diabetes 62:10 (2013), 3404–3417.
    • (2013) Diabetes , vol.62 , Issue.10 , pp. 3404-3417
    • Jing, E.1    O'Neill, B.T.2    Rardin, M.J.3    Kleinridders, A.4    Ilkeyeva, O.R.5    Ussar, S.6
  • 56
    • 79953752384 scopus 로고    scopus 로고
    • PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
    • Bai, P., Cantó, C., Oudart, H., Brunyánszki, A., Cen, Y., Thomas, C., et al. PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metabolism 13:4 (2011), 461–468.
    • (2011) Cell Metabolism , vol.13 , Issue.4 , pp. 461-468
    • Bai, P.1    Cantó, C.2    Oudart, H.3    Brunyánszki, A.4    Cen, Y.5    Thomas, C.6
  • 57
    • 84899103245 scopus 로고    scopus 로고
    • MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1alpha network in skeletal muscle
    • Mohamed, J.S., Hajira, A., Pardo, P.S., Boriek, A.M., MicroRNA-149 inhibits PARP-2 and promotes mitochondrial biogenesis via SIRT-1/PGC-1alpha network in skeletal muscle. Diabetes 63:5 (2014), 1546–1559.
    • (2014) Diabetes , vol.63 , Issue.5 , pp. 1546-1559
    • Mohamed, J.S.1    Hajira, A.2    Pardo, P.S.3    Boriek, A.M.4
  • 58
    • 84902270555 scopus 로고    scopus 로고
    • Pharmacological inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
    • Pirinen, E., Canto, C., Jo, Y.S., Morato, L., Zhang, H., Menzies, K.J., et al. Pharmacological inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. Cell Metabolism 19:6 (2014), 1034–1041.
    • (2014) Cell Metabolism , vol.19 , Issue.6 , pp. 1034-1041
    • Pirinen, E.1    Canto, C.2    Jo, Y.S.3    Morato, L.4    Zhang, H.5    Menzies, K.J.6
  • 59
    • 84919694179 scopus 로고    scopus 로고
    • Activation of SIRT3 by the NAD(+) precursor nicotinamide riboside protects from noise-induced hearing loss
    • Brown, K.D., Maqsood, S., Huang, J.Y., Pan, Y., Harkcom, W., Li, W., et al. Activation of SIRT3 by the NAD(+) precursor nicotinamide riboside protects from noise-induced hearing loss. Cell Metabolism 20:6 (2014), 1059–1068.
    • (2014) Cell Metabolism , vol.20 , Issue.6 , pp. 1059-1068
    • Brown, K.D.1    Maqsood, S.2    Huang, J.Y.3    Pan, Y.4    Harkcom, W.5    Li, W.6
  • 60
    • 84928734998 scopus 로고    scopus 로고
    • Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model
    • Long, A.N., Owens, K., Schlappal, A.E., Kristian, T., Fishman, P.S., Schuh, R.A., Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model. BMC Neurology, 15, 2015, 19.
    • (2015) BMC Neurology , vol.15 , pp. 19
    • Long, A.N.1    Owens, K.2    Schlappal, A.E.3    Kristian, T.4    Fishman, P.S.5    Schuh, R.A.6
  • 61
    • 35549002189 scopus 로고    scopus 로고
    • Nampt/PBEF/visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme
    • Revollo, J.R., Korner, A., Mills, K.F., Satoh, A., Wang, T., Garten, A., et al. Nampt/PBEF/visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metabolism 6:5 (2007), 363–375.
    • (2007) Cell Metabolism , vol.6 , Issue.5 , pp. 363-375
    • Revollo, J.R.1    Korner, A.2    Mills, K.F.3    Satoh, A.4    Wang, T.5    Garten, A.6
  • 62
    • 38349112898 scopus 로고    scopus 로고
    • Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice
    • Ramsey, K.M., Mills, K.F., Satoh, A., Imai, S., Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice. Aging Cell 7:1 (2008), 78–88.
    • (2008) Aging Cell , vol.7 , Issue.1 , pp. 78-88
    • Ramsey, K.M.1    Mills, K.F.2    Satoh, A.3    Imai, S.4
  • 63
    • 82455212299 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function
    • Caton, P.W., Kieswich, J., Yaqoob, M.M., Holness, M.J., Sugden, M.C., Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function. Diabetologia 54:12 (2011), 3083–3092.
    • (2011) Diabetologia , vol.54 , Issue.12 , pp. 3083-3092
    • Caton, P.W.1    Kieswich, J.2    Yaqoob, M.M.3    Holness, M.J.4    Sugden, M.C.5
  • 65
    • 33748174151 scopus 로고    scopus 로고
    • Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
    • Sasaki, Y., Araki, T., Milbrandt, J., Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. The Journal of Neuroscience 26:33 (2006), 8484–8491.
    • (2006) The Journal of Neuroscience , vol.26 , Issue.33 , pp. 8484-8491
    • Sasaki, Y.1    Araki, T.2    Milbrandt, J.3
  • 66
    • 84941890888 scopus 로고    scopus 로고
    • In vivo monitoring of transcriptional dynamics after lower-limb muscle injury enables quantitative classification of healing
    • Aguilar, C.A., Shcherbina, A., Ricke, D.O., Pop, R., Carrigan, C.T., Gifford, C.A., et al. In vivo monitoring of transcriptional dynamics after lower-limb muscle injury enables quantitative classification of healing. Scientific Reports, 5, 2015, 13885.
    • (2015) Scientific Reports , vol.5 , pp. 13885
    • Aguilar, C.A.1    Shcherbina, A.2    Ricke, D.O.3    Pop, R.4    Carrigan, C.T.5    Gifford, C.A.6
  • 67
    • 84944704134 scopus 로고    scopus 로고
    • Lethal cardiomyopathy in mice lacking transferrin receptor in the heart
    • Xu, W., Barrientos, T., Mao, L., Rockman, H.A., Sauve, A.A., Andrews, N.C., Lethal cardiomyopathy in mice lacking transferrin receptor in the heart. Cell Reports 13:3 (2015), 533–545.
    • (2015) Cell Reports , vol.13 , Issue.3 , pp. 533-545
    • Xu, W.1    Barrientos, T.2    Mao, L.3    Rockman, H.A.4    Sauve, A.A.5    Andrews, N.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.