NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Nature Communications

Volumn 7, Issue , 2016, Pages

  Ratajczak, Joanna ^a,b   Joffraud, Magali ^a   Trammell, Samuel A J ^c   Ras, Rosa ^d   Canela, Nuria ^d   Boutant, Marie ^a   Kulkarni, Sameer S ^a   Rodrigues, Marcelo ^c,e   Redpath, Philip ^e   Migaud, Marie E ^c,e   Auwerx, Johan ^b   Yanes, Oscar ^d,f   Brenner, Charles ^c   Cantó, Carles ^a,b  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

^b EPFL   (Switzerland)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^e QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE RIBOSIDE; NICOTINAMIDE RIBOSIDE KINASE 1; NICOTINIC ACID; STABLE ISOTOPE; UNCLASSIFIED DRUG; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE-BETA-RIBOSIDE; NMRK1 PROTEIN, HUMAN; PHOSPHOTRANSFERASE;

BIOASSAY; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; MAMMAL; METABOLISM; NERVOUS SYSTEM DISORDER; PHYSIOLOGY;

3T3 CELL LINE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME METABOLISM; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC GAIN; HEPG2 CELL LINE; ISOTOPE LABELING; LIVER CELL; LOSS OF FUNCTION MUTATION; MAMMAL CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; HEP-G2 CELL LINE; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; MAMMAL; METABOLISM;

MAMMALIA;

ANIMALS; HEP G2 CELLS; HEPATOCYTES; HUMANS; INJECTIONS, INTRAPERITONEAL; MAMMALS; MICE, KNOCKOUT; NAD; NIACINAMIDE; NICOTINAMIDE MONONUCLEOTIDE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 84991294515     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms13103     Document Type: Article

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