Nicotinamide riboside, a form of vitamin B3 and NAD + precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

Pain

Volumn 158, Issue 5, 2017, Pages 962-972

  Hamity, Marta V ^a   White, Stephanie R ^a   Walder, Roxanne Y ^a   Schmidt, Mark S ^a   Brenner, Charles ^a   Hammond, Donna L ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Chemotherapy induced peripheral neuropathy; NAD +; Nicotinamide riboside; Paclitaxel; Place escape avoidance paradigm

Indexed keywords

LEVACECARNINE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE RIBOSIDE; PACLITAXEL; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; NICOTINAMIDE-BETA-RIBOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVERSIVE BEHAVIOR; BONE MARROW SUPPRESSION; CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY; FEMALE; HYPERSENSITIVITY; LOCOMOTION; MEASUREMENT; NOCICEPTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE PHOSPHORYLATION; PRECURSOR; PRIORITY JOURNAL; RAT; VITAMIN BLOOD LEVEL; ADULT; ANALGESIA; ANTIBIOTIC THERAPY; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; SPRAGUE DAWLEY RAT; WEIGHT REDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; EOSINOPHIL; ESCAPE BEHAVIOR; HYPERALGESIA; LEUKOCYTE COUNT; NEUTROPHIL; NONPARAMETRIC TEST; PAIN MEASUREMENT; PATHOLOGY; PERIPHERAL NERVOUS SYSTEM DISEASES; TIME FACTOR;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DISEASE MODELS, ANIMAL; EOSINOPHILS; ESCAPE REACTION; FEMALE; HYPERALGESIA; LEUKOCYTE COUNT; LOCOMOTION; NAD; NEUTROPHILS; NIACINAMIDE; NOCICEPTION; PACLITAXEL; PAIN MEASUREMENT; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 85021308770     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000862     Document Type: Article

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