-
2
-
-
0037938680
-
Growth retarding effect of corn in niacin-low rations and its counteraction by tryptophan
-
Krehl WA, Trepley LJ, Sarma PS, Elvehjem CA (1945) Growth retarding effect of corn in niacin-low rations and its counteraction by tryptophan. Science 101: 489-490.
-
(1945)
Science
, vol.101
, pp. 489-490
-
-
Krehl, W.A.1
Trepley, L.J.2
Sarma, P.S.3
Elvehjem, C.A.4
-
5
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403: 795-800.
-
(2000)
Nature
, vol.403
, pp. 795-800
-
-
Imai, S.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
6
-
-
0034687694
-
Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
-
Tanner KG, Landry J, Sternglanz R, Denu JM (2000) Silent information regulator 2 family of NAD-dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose. Proc Natl Acad Sci U S A 97: 14178-14182.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14178-14182
-
-
Tanner, K.G.1
Landry, J.2
Sternglanz, R.3
Denu, J.M.4
-
8
-
-
0034705129
-
The silencing protein Sir2 and its homologs are NAD-dependent protein deacetylases
-
Landry J, Sutton A, Tafrov ST, Heller RC, Stebbins J, et al. (2000) The silencing protein Sir2 and its homologs are NAD-dependent protein deacetylases. Proc Natl Acad Sci U S A 97: 5807-5811.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 5807-5811
-
-
Landry, J.1
Sutton, A.2
Tafrov, S.T.3
Heller, R.C.4
Stebbins, J.5
-
9
-
-
0035895275
-
Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product
-
Tanny JC, Moazed D (2001) Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product. Proc Natl Acad Sci U S A 98: 415-420.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 415-420
-
-
Tanny, J.C.1
Moazed, D.2
-
10
-
-
0034703217
-
Requirement of NAD and Sir2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin SJ, Defossez PA, Guarente L (2000) Requirement of NAD and Sir2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289: 2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
11
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-230.
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
12
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, et al. (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430: 686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
-
13
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, et al. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444: 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
-
14
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating Sirt1 and PGC-1alpha
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, et al. (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating Sirt1 and PGC-1alpha. Cell 127: 1109-1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
-
15
-
-
34247502715
-
Nicotinamide riboside promotes sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD(+)
-
Belenky P, Racette FG, Bogan KL, McClure JM, Smith JS, et al. (2007) Nicotinamide riboside promotes sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD(+). Cell 129: 473-484.
-
(2007)
Cell
, vol.129
, pp. 473-484
-
-
Belenky, P.1
Racette, F.G.2
Bogan, K.L.3
McClure, J.M.4
Smith, J.S.5
-
16
-
-
33748174151
-
Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
-
Sasaki Y, Araki T, Milbrandt J (2006) Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. J Neurosci 26: 8484-8491.
-
(2006)
J Neurosci
, vol.26
, pp. 8484-8491
-
-
Sasaki, Y.1
Araki, T.2
Milbrandt, J.3
-
17
-
-
4043165678
-
Increased nuclear NAD biosynthesis and Sirt1 activation prevent axonal degeneration
-
Araki T, Sasaki Y, Milbrandt J (2004) Increased nuclear NAD biosynthesis and Sirt1 activation prevent axonal degeneration. Science 305: 1010-1013.
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
18
-
-
23744474976
-
A local mechanism mediates NAD-dependent protection of axon degeneration
-
Wang J, Zhai Q, Chen Y, Lin E, Gu W, et al. (2005) A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol 170: 349-355.
-
(2005)
J Cell Biol
, vol.170
, pp. 349-355
-
-
Wang, J.1
Zhai, Q.2
Chen, Y.3
Lin, E.4
Gu, W.5
-
19
-
-
0035040209
-
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases
-
Van Rompay AR, Norda A, Linden K, Johansson M, Karlsson A (2001) Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. Mol Pharmacol 59: 1181-1186.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 1181-1186
-
-
Van Rompay, A.R.1
Norda, A.2
Linden, K.3
Johansson, M.4
Karlsson, A.5
-
20
-
-
0034623086
-
Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A
-
Yun M, Park CG, Kim JY, Rock CO, Jackowski S, et al. (2000) Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A. J Biol Chem 275: 28093-28099.
-
(2000)
J Biol Chem
, vol.275
, pp. 28093-28099
-
-
Yun, M.1
Park, C.G.2
Kim, J.Y.3
Rock, C.O.4
Jackowski, S.5
-
21
-
-
0042377362
-
+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase
-
+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase. J Biol Chem 278: 33049-33055.
-
(2003)
J Biol Chem
, vol.278
, pp. 33049-33055
-
-
Bieganowski, P.1
Pace, H.C.2
Brenner, C.3
-
22
-
-
0020977296
-
Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity
-
Cooney DA, Jayaram HN, Glazer RI, Kelley JA, Marquez VE, et al. (1983) Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity. Adv Enzyme Regul 21: 271-303.
-
(1983)
Adv Enzyme Regul
, vol.21
, pp. 271-303
-
-
Cooney, D.A.1
Jayaram, H.N.2
Glazer, R.I.3
Kelley, J.A.4
Marquez, V.E.5
-
23
-
-
0022325950
-
Resolution of phase ambiguity in macromolecular crystallography
-
Wang BC (1985) Resolution of phase ambiguity in macromolecular crystallography. Methods Enzymol 115: 90-112.
-
(1985)
Methods Enzymol
, vol.115
, pp. 90-112
-
-
Wang, B.C.1
-
25
-
-
0013054388
-
Macromolecular phasing with SHELE
-
Sheldrick GM (2002) Macromolecular phasing with SHELE. Z Krystallogr 217: 644-650.
-
(2002)
Z Krystallogr
, vol.217
, pp. 644-650
-
-
Sheldrick, G.M.1
-
26
-
-
0028871926
-
Dali: A network tool for protein structure comparison
-
Holm L, Sander C (1995) Dali: A network tool for protein structure comparison. Trends Biochem Sci 20: 478-480.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 478-480
-
-
Holm, L.1
Sander, C.2
-
27
-
-
2342600247
-
Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase
-
Suzuki NN, Koizumi K, Fukushima M, Matsuda A, Inagaki F (2004) Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase. Structure 12: 751-764.
-
(2004)
Structure
, vol.12
, pp. 751-764
-
-
Suzuki, N.N.1
Koizumi, K.2
Fukushima, M.3
Matsuda, A.4
Inagaki, F.5
-
28
-
-
0032529583
-
Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+
-
Berry MB, Phillips GN Jr. (1998) Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+. Proteins 32: 276-288.
-
(1998)
Proteins
, vol.32
, pp. 276-288
-
-
Berry, M.B.1
Phillips Jr., G.N.2
-
29
-
-
0036040533
-
Conformational changes during the catalytic cycle of gluconate kinase as revealed by x-ray crystallography
-
Kraft L, Sprenger GA, Lindqvist Y (2002) Conformational changes during the catalytic cycle of gluconate kinase as revealed by x-ray crystallography. J Mol Biol 318: 1057-1069.
-
(2002)
J Mol Biol
, vol.318
, pp. 1057-1069
-
-
Kraft, L.1
Sprenger, G.A.2
Lindqvist, Y.3
-
30
-
-
0025048136
-
The P-loop - A common motif in ATP- and GTP-binding proteins
-
Saraste M, Sibbald PR, Wittinghofer A (1990) The P-loop - A common motif in ATP- and GTP-binding proteins. Trends Biochem Sci 15: 430-434.
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 430-434
-
-
Saraste, M.1
Sibbald, P.R.2
Wittinghofer, A.3
-
32
-
-
0027024417
-
Induced-fit movements in adenylate kinases
-
Schulz GE (1992) Induced-fit movements in adenylate kinases. Faraday Discuss 93: 85-93.
-
(1992)
Faraday Discuss
, vol.93
, pp. 85-93
-
-
Schulz, G.E.1
-
33
-
-
0032513122
-
The yeast gene YJR025C encodes a 3-hydroxyanthranilic acid dioxygenase and is involved in nicotinic acid biosynthesis
-
Kucharczyk R, Zagulski M, Rytka J, Herbert CJ (1998) The yeast gene YJR025C encodes a 3-hydroxyanthranilic acid dioxygenase and is involved in nicotinic acid biosynthesis. FEBS Lett 424: 127-130.
-
(1998)
FEBS Lett
, vol.424
, pp. 127-130
-
-
Kucharczyk, R.1
Zagulski, M.2
Rytka, J.3
Herbert, C.J.4
-
34
-
-
70449213670
-
Biosynthesis of diphosphopyridine nucleotide II. Enzymatic aspects
-
Preiss J, Handler P (1958) Biosynthesis of diphosphopyridine nucleotide II. Enzymatic aspects. J Biol Chem 233: 493-500.
-
(1958)
J Biol Chem
, vol.233
, pp. 493-500
-
-
Preiss, J.1
Handler, P.2
-
35
-
-
0036244225
-
Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase
-
Yalowitz JA, Jayaram HN (2002) Modulation of cytotoxicity of benzamide riboside by expression of NMN adenylyltransferase. Curr Med Chem 9: 749-758.
-
(2002)
Curr Med Chem
, vol.9
, pp. 749-758
-
-
Yalowitz, J.A.1
Jayaram, H.N.2
-
36
-
-
0031059866
-
Processing of x-ray diffraction data collected in oscillation mode
-
Otwinowski Z, Minor W (1997) Processing of x-ray diffraction data collected in oscillation mode. Methods Enzymol 276: 307-326.
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
37
-
-
0032964481
-
Automated protein model building combined with iterative structure refinement
-
Perrakis A, Morris R, Lamzin VS (1999) Automated protein model building combined with iterative structure refinement. Nat Struct Biol 6: 458-463.
-
(1999)
Nat Struct Biol
, vol.6
, pp. 458-463
-
-
Perrakis, A.1
Morris, R.2
Lamzin, V.S.3
-
39
-
-
7544226311
-
PRODRG: A tool for high-throughput crystallography of protein-ligand complexes
-
Schuttelkopf AW, van Aalten DM (2004) PRODRG: A tool for high-throughput crystallography of protein-ligand complexes. Acta Crystallogr D Biol Crystallogr 60: 1355-1363.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 1355-1363
-
-
Schuttelkopf, A.W.1
van Aalten, D.M.2
-
41
-
-
3242886389
-
MOLPROBITY: Structure validation and all-atom contact analysis for nucleic acids and their complexes
-
Davis IW, Murray LW, Richardson JS, Richardson DC (2004) MOLPROBITY: Structure validation and all-atom contact analysis for nucleic acids and their complexes. Nucleic Acids Res 32: W615-619.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Davis, I.W.1
Murray, L.W.2
Richardson, J.S.3
Richardson, D.C.4
-
43
-
-
13444307044
-
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
-
Krissinel E, Henrick K (2004) Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr D Biol Crystallogr 60: 2256-2268.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 2256-2268
-
-
Krissinel, E.1
Henrick, K.2
-
44
-
-
0033529707
-
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis
-
Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, et al. (1999) Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285: 901-906.
-
(1999)
Science
, vol.285
, pp. 901-906
-
-
Winzeler, E.A.1
Shoemaker, D.D.2
Astromoff, A.3
Liang, H.4
Anderson, K.5
|