Epistatic networks jointly influence phenotypes related to metabolic disease and gene expression in diversity outbred mice

Genetics

Volumn 206, Issue 2, 2017, Pages 621-639

  Tyler, Anna L ^a   Ji, Bo ^a   Gatti, Daniel M ^a   Munger, Steven C ^a   Churchill, Gary A ^a   Svenson, Karen L ^a   Carter, Gregory W ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

Epistasis; MPP; Multiparental populations; Outbred mouse population; Pleiotropy; Systems genetics

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL; LEPTIN; TRANSCRIPTOME; TRIACYLGLYCEROL;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY COMPOSITION; COMBINED ANALYSIS OF PLEIOTROPY AND EPISTASIS; CONTROLLED STUDY; DIETARY INTAKE; EPISTASIS; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE MAPPING; GENETIC ANALYSIS; GENETIC VARIABILITY; HAPLOTYPE; HEREDITY; LIPID DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; PHENOTYPIC VARIATION; PHYSIOLOGICAL PROCESS; PLEIOTROPY; POPULATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; WEIGHTED GENE COEXPRESSION NETWORK ANALYSIS; ANIMAL; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC VARIATION; GENETICS; GENOMICS; GENOTYPE; HUMAN; PATHOLOGY; PHENOTYPE;

ANIMALS; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENETIC PLEIOTROPY; GENETIC VARIATION; GENOMICS; GENOTYPE; HAPLOTYPES; HUMANS; METABOLIC DISEASES; MICE; MODELS, GENETIC; PHENOTYPE; QUANTITATIVE TRAIT LOCI;

EID: 85020304250     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.116.198051     Document Type: Article

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