Mediation Analysis Demonstrates That Trans-eQTLs Are Often Explained by Cis-Mediation: A Genome-Wide Analysis among 1,800 South Asians

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Pierce, Brandon L ^a,b   Tong, Lin ^a   Chen, Lin S ^a   Rahaman, Ronald ^a   Argos, Maria ^a   Jasmine, Farzana ^a   Roy, Shantanu ^a   Paul Brutus, Rachelle ^a   Westra, Harm Jan ^c   Franke, Lude ^c   Esko, Tonu ^d   Zaman, Rakibuz ^e   Islam, Tariqul ^e   Rahman, Mahfuzar ^e,f   Baron, John A ^g   Kibriya, Muhammad G ^a   Ahsan, Habibul ^a,b,h,i  

^a THE UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d UNIVERSITY OF TARTU   (Estonia)

^e UChicago Research Bangladesh   (Bangladesh)

^f RESEARCH AND EVALUATION DIVISION   (Bangladesh)

^g UNIVERSITY OF NORTH CAROLINA   (United States)

^h UNIVERSITY OF CHICAGO   (United States)

ⁱ THE UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BANGLADESHI; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; EUROPEAN; EXPRESSION QUANTITATIVE TRAIT LOCUS; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; HUMAN CELL; MALE; MEDIATION ANALYSIS; MICROARRAY ANALYSIS; MONONUCLEAR CELL; QUANTITATIVE TRAIT LOCUS; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH ASIAN; ASIA; ASIAN CONTINENTAL ANCESTRY GROUP; BANGLADESH; CHEMOPROPHYLAXIS; COMPUTER SIMULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; RANDOMIZED CONTROLLED TRIAL; SKIN NEOPLASMS; STATISTICS AND NUMERICAL DATA;

ALPHA TOCOPHEROL; SELENIUM;

ASIA; ASIAN CONTINENTAL ANCESTRY GROUP; BANGLADESH; CHEMOPREVENTION; COMPUTER SIMULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; QUANTITATIVE TRAIT LOCI; SELENIUM; SKIN NEOPLASMS; VITAMIN E;

EID: 84919625810     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004818     Document Type: Article

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