Diversity outbred mice at 21: Maintaining allelic variation in the face of selection

G3: Genes, Genomes, Genetics

Volumn 6, Issue 12, 2016, Pages 3893-3902

  Chesler, Elissa J ^a   Gatti, Daniel M ^a   Morgan, Andrew P ^b   Strobel, Marge ^a   Trepanier, Laura ^a   Oberbeck, Denesa ^c   McWeeney, Shannon ^c   Hitzemann, Robert ^c   Ferris, Martin ^b   McMullan, Rachel ^b   Clayshultle, Amelia ^b   Bell, Timothy A ^b   de Villena, Fernando Pardo Manuel ^b   Churchill, Gary A ^a  

^a JACKSON LABORATORY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Aneuploidy; Meiotic drive; Multiparent Advanced Generation Inter Cross (MAGIC); Multiparental populations MPP; Transmission ratio distortion

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME 2; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE STRUCTURE; GENETIC RESOURCE; GENETIC VARIABILITY; GENETIC VARIATION; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; LITTER SIZE; MALE; MATING SUCCESS; MATING TYPE; MITOCHONDRIAL GENOME; MITOCHONDRION; MOUSE; NONHUMAN; SEX CHROMOSOME; SEX CHROMOSOME ABERRATION; SEX RATIO; X CHROMOSOME; Y CHROMOSOME; ANIMAL; BIOLOGY; BREEDING; CROSS BREEDING; GENE LOCUS; GENETIC SELECTION; GENETICS; GENOME; GENOMICS; MOLECULAR GENETICS; MUTATION; PHENOTYPE; POPULATION GENETICS; PROCEDURES;

ALLELES; ANIMALS; BREEDING; COMPUTATIONAL BIOLOGY; CROSSES, GENETIC; FEMALE; GENE FREQUENCY; GENETIC LOCI; GENETIC VARIATION; GENETICS, POPULATION; GENOME; GENOMICS; HAPLOTYPES; MALE; MICE; MITOCHONDRIA; MOLECULAR SEQUENCE ANNOTATION; MUTATION; PHENOTYPE; SELECTION, GENETIC; SEX CHROMOSOME ABERRATIONS; SEX RATIO;

EID: 85008506997     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.116.035527     Document Type: Article

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