-
1
-
-
34548572892
-
Bile acid transporters: structure, function, regulation and pathophysiological implications
-
Alrefai, W. A., and R. K. Gill. 2007. Bile acid transporters: structure, function, regulation and pathophysiological implications. Pharm. Res. 24:1803–1823.
-
(2007)
Pharm. Res.
, vol.24
, pp. 1803-1823
-
-
Alrefai, W.A.1
Gill, R.K.2
-
2
-
-
34247197769
-
Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells
-
Alrefai, W. A., S. Saksena, S. Tyagi, R. K. Gill, K. Ramaswamy, and P. K. Dudeja. 2007. Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells. Dig. Dis. Sci. 52:1270–1278.
-
(2007)
Dig. Dis. Sci.
, vol.52
, pp. 1270-1278
-
-
Alrefai, W.A.1
Saksena, S.2
Tyagi, S.3
Gill, R.K.4
Ramaswamy, K.5
Dudeja, P.K.6
-
3
-
-
33947631511
-
IL-1beta causes an increase in intestinal epithelial tight junction permeability
-
Al-Sadi, R. M., and T. Y. Ma. 2007. IL-1beta causes an increase in intestinal epithelial tight junction permeability. J. Immunol. 178:4641–4649.
-
(2007)
J. Immunol.
, vol.178
, pp. 4641-4649
-
-
Al-Sadi, R.M.1
Ma, T.Y.2
-
5
-
-
79952438594
-
Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84
-
Ao, M., J. Venkatasubramanian, C. Boonkaewwan, N. Ganesan, A. Syed, R. V. Benya, et al. 2011. Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84. Dig. Dis. Sci. 56:339–351.
-
(2011)
Dig. Dis. Sci.
, vol.56
, pp. 339-351
-
-
Ao, M.1
Venkatasubramanian, J.2
Boonkaewwan, C.3
Ganesan, N.4
Syed, A.5
Benya, R.V.6
-
6
-
-
84881621285
-
Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells
-
Ao, M., J. Sarathy, J. Domingue, W. A. Alrefai, and M. C. Rao. 2013. Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells. Am. J. Physiol. Cell Physiol. 305:C447–C456.
-
(2013)
Am. J. Physiol. Cell Physiol.
, vol.305
, pp. C447-C456
-
-
Ao, M.1
Sarathy, J.2
Domingue, J.3
Alrefai, W.A.4
Rao, M.C.5
-
7
-
-
84983677567
-
Lithocholic acid attenuates cAMP-dependent Cl- secretion in human colonic epithelial T84 cells
-
Ao, M., J. C. Domingue, N. Khan, F. Javed, K. Osmani, J. Sarathy, et al. 2016. Lithocholic acid attenuates cAMP-dependent Cl- secretion in human colonic epithelial T84 cells. Am. J. Physiol. Cell Physiol. 310:C1010–C1023.
-
(2016)
Am. J. Physiol. Cell Physiol.
, vol.310
, pp. C1010-C1023
-
-
Ao, M.1
Domingue, J.C.2
Khan, N.3
Javed, F.4
Osmani, K.5
Sarathy, J.6
-
8
-
-
2642531332
-
The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2
-
Araki, Y., A. Andoh, H. Bamba, K. Yoshikawa, H. Doi, Y. Komai, et al. 2003. The cytotoxicity of hydrophobic bile acids is ameliorated by more hydrophilic bile acids in intestinal cell lines IEC-6 and Caco-2. Oncol. Rep. 10: 1931–1936.
-
(2003)
Oncol. Rep.
, vol.10
, pp. 1931-1936
-
-
Araki, Y.1
Andoh, A.2
Bamba, H.3
Yoshikawa, K.4
Doi, H.5
Komai, Y.6
-
9
-
-
23844475827
-
Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line
-
Araki, Y., T. Katoh, A. Ogawa, S. Bamba, A. Andoh, S. Koyama, et al. 2005. Bile acid modulates transepithelial permeability via the generation of reactive oxygen species in the Caco-2 cell line. Free Radic. Biol. Med. 39:769–780.
-
(2005)
Free Radic. Biol. Med.
, vol.39
, pp. 769-780
-
-
Araki, Y.1
Katoh, T.2
Ogawa, A.3
Bamba, S.4
Andoh, A.5
Koyama, S.6
-
11
-
-
0029799520
-
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
-
Balda, M. S., J. A. Whitney, C. Flores, S. Gonzalez, M. Cereijido, and K. Matter. 1996. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J. Cell Biol. 134:1031–1049.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1031-1049
-
-
Balda, M.S.1
Whitney, J.A.2
Flores, C.3
Gonzalez, S.4
Cereijido, M.5
Matter, K.6
-
12
-
-
0034019626
-
Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: role of the microtubule cytoskeleton
-
Banan, A., S. Choudhary, Y. Zhang, J. Z. Fields, and A. Keshavarzian. 2000. Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: role of the microtubule cytoskeleton. Free Radic. Biol. Med. 28:727–738.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 727-738
-
-
Banan, A.1
Choudhary, S.2
Zhang, Y.3
Fields, J.Z.4
Keshavarzian, A.5
-
13
-
-
84875255442
-
Bile acids in the colon, from healthy to cytotoxic molecules
-
Barrasa, J. I., N. Olmo, M. A. Lizarbe, and J. Turnay. 2013. Bile acids in the colon, from healthy to cytotoxic molecules. Toxicol. In Vitro 27:964–977.
-
(2013)
Toxicol. In Vitro
, vol.27
, pp. 964-977
-
-
Barrasa, J.I.1
Olmo, N.2
Lizarbe, M.A.3
Turnay, J.4
-
14
-
-
39149116716
-
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis
-
Beilke, L. D., D. G. Besselsen, Q. Cheng, S. Kulkarni, A. L. Slitt, and N. J. Cherrington. 2008. Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicol. Sci. 102:196–204.
-
(2008)
Toxicol. Sci.
, vol.102
, pp. 196-204
-
-
Beilke, L.D.1
Besselsen, D.G.2
Cheng, Q.3
Kulkarni, S.4
Slitt, A.L.5
Cherrington, N.J.6
-
16
-
-
33746081253
-
Causes of chronic diarrhea
-
Binder, H. J. 2006. Causes of chronic diarrhea. N. Engl. J. Med. 355:236–239.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 236-239
-
-
Binder, H.J.1
-
17
-
-
0015633174
-
Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon
-
Binder, H. J., and C. L. Rawlins. 1973. Effect of conjugated dihydroxy bile salts on electrolyte transport in rat colon. J. Clin. Investig. 52:1460–1466.
-
(1973)
J. Clin. Investig.
, vol.52
, pp. 1460-1466
-
-
Binder, H.J.1
Rawlins, C.L.2
-
18
-
-
45549104311
-
Specific immunomodulatory and secretory activities of stevioside and steviol in intestinal cells
-
Boonkaewwan, C., M. Ao, C. Toskulkao, and M. C. Rao. 2008. Specific immunomodulatory and secretory activities of stevioside and steviol in intestinal cells. J. Agri. Food Chem. 56:3777–3784.
-
(2008)
J. Agri. Food Chem.
, vol.56
, pp. 3777-3784
-
-
Boonkaewwan, C.1
Ao, M.2
Toskulkao, C.3
Rao, M.C.4
-
19
-
-
0345447585
-
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
-
Bruewer, M., A. Luegering, T. Kucharzik, C. A. Parkos, J. L. Madara, A. M. Hopkins, et al. 2003. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J. Immunol. 171:6164–6172.
-
(2003)
J. Immunol.
, vol.171
, pp. 6164-6172
-
-
Bruewer, M.1
Luegering, A.2
Kucharzik, T.3
Parkos, C.A.4
Madara, J.L.5
Hopkins, A.M.6
-
20
-
-
84865530973
-
Methods to examine tight junction physiology in cancer stem cells: TEER, paracellular permeability, and dilution potential measurements
-
Buchert, M., K. Turksen, and F. Hollande. 2012. Methods to examine tight junction physiology in cancer stem cells: TEER, paracellular permeability, and dilution potential measurements. Stem Cell Rev. 8:1030–1034.
-
(2012)
Stem Cell Rev.
, vol.8
, pp. 1030-1034
-
-
Buchert, M.1
Turksen, K.2
Hollande, F.3
-
21
-
-
0026657890
-
Differential effects of chenodeoxycholic and ursodeoxycholic acids on interleukin 1, interleukin 6 and tumor necrosis factor-alpha production by monocytes
-
Calmus, Y., J. Guechot, P. Podevin, M. T. Bonnefis, J. Giboudeau, and R. Poupon. 1992. Differential effects of chenodeoxycholic and ursodeoxycholic acids on interleukin 1, interleukin 6 and tumor necrosis factor-alpha production by monocytes. Hepatology 16:719–723.
-
(1992)
Hepatology
, vol.16
, pp. 719-723
-
-
Calmus, Y.1
Guechot, J.2
Podevin, P.3
Bonnefis, M.T.4
Giboudeau, J.5
Poupon, R.6
-
22
-
-
63249123919
-
Cytokine regulation of tight junctions
-
Capaldo, C. T., and A. Nusrat. 2009. Cytokine regulation of tight junctions. Biochem. Biophys. Acta. 1788:864–871.
-
(2009)
Biochem. Biophys. Acta.
, vol.1788
, pp. 864-871
-
-
Capaldo, C.T.1
Nusrat, A.2
-
23
-
-
53549094941
-
Increased paracellular absorption by bile salts and P-glycoprotein stimulated efflux of otilonium bromide in Caco-2 cells monolayers as a model of intestinal barrier
-
Catalioto, R. M., A. Triolo, S. Giuliani, M. Altamura, S. Evangelista, and C. A. Maggi. 2008. Increased paracellular absorption by bile salts and P-glycoprotein stimulated efflux of otilonium bromide in Caco-2 cells monolayers as a model of intestinal barrier. J. Pharm. Sci. 97:4087–4100.
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 4087-4100
-
-
Catalioto, R.M.1
Triolo, A.2
Giuliani, S.3
Altamura, M.4
Evangelista, S.5
Maggi, C.A.6
-
24
-
-
0018694645
-
Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon
-
Chadwick, V. S., T. S. Gaginella, G. L. Carlson, J. C. Debongnie, S. F. Phillips, and A. F. Hofmann. 1979. Effect of molecular structure on bile acid-induced alterations in absorptive function, permeability, and morphology in the perfused rabbit colon. J. Lab. Clin. Med. 94:661–674.
-
(1979)
J. Lab. Clin. Med.
, vol.94
, pp. 661-674
-
-
Chadwick, V.S.1
Gaginella, T.S.2
Carlson, G.L.3
Debongnie, J.C.4
Phillips, S.F.5
Hofmann, A.F.6
-
25
-
-
0023150913
-
Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids
-
Craven, P. A., J. Pfanstiel, and F. R. DeRubertis. 1987. Role of activation of protein kinase C in the stimulation of colonic epithelial proliferation and reactive oxygen formation by bile acids. J. Clin. Investig. 79:532–541.
-
(1987)
J. Clin. Investig.
, vol.79
, pp. 532-541
-
-
Craven, P.A.1
Pfanstiel, J.2
DeRubertis, F.R.3
-
26
-
-
84862853385
-
Myosin light chain kinase: pulling the strings of epithelial tight junction function
-
Cunningham, K. E., and J. R. Turner. 2012. Myosin light chain kinase: pulling the strings of epithelial tight junction function. Ann. N. Y. Acad. Sci. 1258:34–42.
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1258
, pp. 34-42
-
-
Cunningham, K.E.1
Turner, J.R.2
-
27
-
-
0038410546
-
Bile Secretion and the Enterohepatic Circulation
-
in, M. Feldman, L. S. Friedman, L. J. Brandt Saunders, eds., Elsevier Saunders, Philadelphia, PA
-
Dawson, P. A. 2016. Bile Secretion and the Enterohepatic Circulation. Pp. 1085–1099 in M. Feldman, L. S. Friedman, L. J. Brandt Saunders, eds. Sleisenger and Fordtran's gastrointestinal and liver disease. Elsevier Saunders, Philadelphia, PA.
-
(2016)
Sleisenger and Fordtran's gastrointestinal and liver disease
, pp. 1085-1099
-
-
Dawson, P.A.1
-
28
-
-
0024428298
-
Cl- secretion induced by bile salts. a study of the mechanism of action based on a cultured colonic epithelial cell line
-
Dharmsathaphorn, K., P. A. Huott, P. Vongkovit, G. Beuerlein, S. J. Pandol, and H. V. Ammon. 1989. Cl- secretion induced by bile salts. a study of the mechanism of action based on a cultured colonic epithelial cell line. J. Clin. Investig. 84:945–953.
-
(1989)
J. Clin. Investig.
, vol.84
, pp. 945-953
-
-
Dharmsathaphorn, K.1
Huott, P.A.2
Vongkovit, P.3
Beuerlein, G.4
Pandol, S.J.5
Ammon, H.V.6
-
29
-
-
84994578302
-
Chenodeoxycholic acid requires activation of EGFR, EPAC and Ca2 + to stimulate CFTR-dependent Cl- secretion in human colonic T84 Cells
-
Domingue, J. C., M. Ao, J. Sarathy, and M. C. Rao. 2016. Chenodeoxycholic acid requires activation of EGFR, EPAC and Ca2 + to stimulate CFTR-dependent Cl- secretion in human colonic T84 Cells. Am. J. Physiol. Cell Physiol. 311:C777–C792.
-
(2016)
Am. J. Physiol. Cell Physiol.
, vol.311
, pp. C777-C792
-
-
Domingue, J.C.1
Ao, M.2
Sarathy, J.3
Rao, M.C.4
-
30
-
-
84861201380
-
Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome
-
Duboc, H., D. Rainteau, S. Rajca, L. Humbert, D. Farabos, M. Maubert, et al. 2012. Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol. Motil. 24(513–520):e246–e517.
-
(2012)
Neurogastroenterol. Motil.
, vol.24
, Issue.513-520
, pp. e246-e517
-
-
Duboc, H.1
Rainteau, D.2
Rajca, S.3
Humbert, L.4
Farabos, D.5
Maubert, M.6
-
31
-
-
0027486788
-
Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
-
Eckmann, L., M. F. Kagnoff, and J. Fierer. 1993. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect. Immun. 61:4569–4574.
-
(1993)
Infect. Immun.
, vol.61
, pp. 4569-4574
-
-
Eckmann, L.1
Kagnoff, M.F.2
Fierer, J.3
-
32
-
-
0000752197
-
Junctional complexes in various epithelia
-
Farquhar, M. G., and G. E. Palade. 1963. Junctional complexes in various epithelia. J. Cell Biol. 17:375–412.
-
(1963)
J. Cell Biol.
, vol.17
, pp. 375-412
-
-
Farquhar, M.G.1
Palade, G.E.2
-
33
-
-
0024387211
-
Bile acids inhibit endotoxin-induced release of tumor necrosis factor by monocytes: an in vitro study
-
Greve, J. W., D. J. Gouma, and W. A. Buurman. 1989. Bile acids inhibit endotoxin-induced release of tumor necrosis factor by monocytes: an in vitro study. Hepatology 10:454–458.
-
(1989)
Hepatology
, vol.10
, pp. 454-458
-
-
Greve, J.W.1
Gouma, D.J.2
Buurman, W.A.3
-
34
-
-
67649216750
-
Intestinal barrier function: molecular regulation and disease pathogenesis
-
quiz 21-22
-
Groschwitz, K. R., and S. P. Hogan. 2009. Intestinal barrier function: molecular regulation and disease pathogenesis. J. Allergy Clin. Immunol. 124:3–20, quiz 21-22.
-
(2009)
J. Allergy Clin. Immunol.
, vol.124
, pp. 3-20
-
-
Groschwitz, K.R.1
Hogan, S.P.2
-
35
-
-
84878506887
-
Claudins and the modulation of tight junction permeability
-
Gunzel, D., and A. S. Yu. 2013. Claudins and the modulation of tight junction permeability. Physiol. Rev. 93:525–569.
-
(2013)
Physiol. Rev.
, vol.93
, pp. 525-569
-
-
Gunzel, D.1
Yu, A.S.2
-
36
-
-
32044459537
-
Bile acids induce ileal damage during experimental necrotizing enterocolitis
-
Halpern, M. D., H. Holubec, T. A. Saunders, K. Dvorak, J. A. Clark, S. M. Doelle, et al. 2006. Bile acids induce ileal damage during experimental necrotizing enterocolitis. Gastroenterology 130:359–372.
-
(2006)
Gastroenterology
, vol.130
, pp. 359-372
-
-
Halpern, M.D.1
Holubec, H.2
Saunders, T.A.3
Dvorak, K.4
Clark, J.A.5
Doelle, S.M.6
-
37
-
-
0024504505
-
Morphologic and functional effects of bile salt on the porcine colon during injury and repair
-
Henrikson, C. K., R. A. Argenzio, J. A. Liacos, and J. Khosla. 1989. Morphologic and functional effects of bile salt on the porcine colon during injury and repair. Lab. Invest. 60:72–87.
-
(1989)
Lab. Invest.
, vol.60
, pp. 72-87
-
-
Henrikson, C.K.1
Argenzio, R.A.2
Liacos, J.A.3
Khosla, J.4
-
38
-
-
0033611305
-
The continuing importance of bile acids in liver and intestinal disease
-
Hofmann, A. F. 1999. The continuing importance of bile acids in liver and intestinal disease. Arch. Intern. Med. 159:2647–2658.
-
(1999)
Arch. Intern. Med.
, vol.159
, pp. 2647-2658
-
-
Hofmann, A.F.1
-
39
-
-
66149115985
-
Bile acids: trying to understand their chemistry and biology with the hope of helping patients
-
Hofmann, A. F. 2009. Bile acids: trying to understand their chemistry and biology with the hope of helping patients. Hepatology 49:1403–1418.
-
(2009)
Hepatology
, vol.49
, pp. 1403-1418
-
-
Hofmann, A.F.1
-
40
-
-
84905053368
-
Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades
-
Hofmann, A. F., and L. R. Hagey. 2014. Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades. J. Lipid Res. 55:1553–1595.
-
(2014)
J. Lipid Res.
, vol.55
, pp. 1553-1595
-
-
Hofmann, A.F.1
Hagey, L.R.2
-
41
-
-
0026623067
-
Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2 + ions
-
Hofmann, A. F., and K. J. Mysels. 1992. Bile acid solubility and precipitation in vitro and in vivo: the role of conjugation, pH, and Ca2 + ions. J. Lipid Res. 33:617–626.
-
(1992)
J. Lipid Res.
, vol.33
, pp. 617-626
-
-
Hofmann, A.F.1
Mysels, K.J.2
-
42
-
-
0021739393
-
Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem
-
Hofmann, A. F., and A. Roda. 1984. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J. Lipid Res. 25:1477–1489.
-
(1984)
J. Lipid Res.
, vol.25
, pp. 1477-1489
-
-
Hofmann, A.F.1
Roda, A.2
-
43
-
-
41349083792
-
Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro
-
Hughes, R., M. J. Kurth, V. McGilligan, H. McGlynn, and I. Rowland. 2008. Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro. Nutr. Cancer 60:259–266.
-
(2008)
Nutr. Cancer
, vol.60
, pp. 259-266
-
-
Hughes, R.1
Kurth, M.J.2
McGilligan, V.3
McGlynn, H.4
Rowland, I.5
-
44
-
-
84868228667
-
Bile acids: an underrecognized and underappreciated cause of chronic diarrhea
-
Islam, R., and J. DiBaise. 2012. Bile acids: an underrecognized and underappreciated cause of chronic diarrhea. Pract. Gastroenterol. 110:32–44.
-
(2012)
Pract. Gastroenterol.
, vol.110
, pp. 32-44
-
-
Islam, R.1
DiBaise, J.2
-
45
-
-
33744960773
-
Deoxycholic acid induces intracellular signaling through membrane perturbations
-
Jean-Louis, S., S. Akare, M. A. Ali, E. A. Jr Mash, E. Meuillet, and J. D. Martinez. 2006. Deoxycholic acid induces intracellular signaling through membrane perturbations. J. Biol. Chem. 281:14948–14960.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14948-14960
-
-
Jean-Louis, S.1
Akare, S.2
Ali, M.A.3
Mash, E.A.4
Meuillet, E.5
Martinez, J.D.6
-
46
-
-
84898653028
-
Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion
-
Jiang, K., C. R. Rankin, P. Nava, R. Sumagin, R. Kamekura, S. R. Stowell, et al. 2014. Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion. J. Biol. Chem. 289:10510–10517.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 10510-10517
-
-
Jiang, K.1
Rankin, C.R.2
Nava, P.3
Sumagin, R.4
Kamekura, R.5
Stowell, S.R.6
-
47
-
-
33846162297
-
Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships
-
Keely, S. J., M. M. Scharl, L. S. Bertelsen, L. R. Hagey, K. E. Barrett, and A. F. Hofmann. 2007. Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships. Am. J. Physiol. Gastrointest. Liver Physiol. 292:G290–G297.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
, pp. G290-G297
-
-
Keely, S.J.1
Scharl, M.M.2
Bertelsen, L.S.3
Hagey, L.R.4
Barrett, K.E.5
Hofmann, A.F.6
-
48
-
-
84877000653
-
Ursodeoxycholic acid attenuates colonic epithelial secretory function
-
Kelly, O. B., M. S. Mroz, J. B. Ward, C. Colliva, M. Scharl, R. Pellicciari, et al. 2013. Ursodeoxycholic acid attenuates colonic epithelial secretory function. J. Physiol. 591:2307–2318.
-
(2013)
J. Physiol.
, vol.591
, pp. 2307-2318
-
-
Kelly, O.B.1
Mroz, M.S.2
Ward, J.B.3
Colliva, C.4
Scharl, M.5
Pellicciari, R.6
-
49
-
-
0029813757
-
Interleukin-8 production by the human colon epithelial cell line HT-29: modulation by interleukin-13
-
Kolios, G., D. A. Robertson, N. J. Jordan, A. Minty, D. Caput, P. Ferrara, et al. 1996. Interleukin-8 production by the human colon epithelial cell line HT-29: modulation by interleukin-13. Br. J. Pharmacol. 119:351–359.
-
(1996)
Br. J. Pharmacol.
, vol.119
, pp. 351-359
-
-
Kolios, G.1
Robertson, D.A.2
Jordan, N.J.3
Minty, A.4
Caput, D.5
Ferrara, P.6
-
50
-
-
84937524388
-
Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases
-
Lee, S. H. 2015. Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases. Intest. Res. 13:11–18.
-
(2015)
Intest. Res.
, vol.13
, pp. 11-18
-
-
Lee, S.H.1
-
51
-
-
84872741573
-
Nuclear receptors in bile acid metabolism
-
Li, T., and J. Y. Chiang. 2013. Nuclear receptors in bile acid metabolism. Drug Metab. Rev. 45:145–155.
-
(2013)
Drug Metab. Rev.
, vol.45
, pp. 145-155
-
-
Li, T.1
Chiang, J.Y.2
-
52
-
-
0031954627
-
Production of proinflammatory cytokines and inflammatory mediators in human intestinal epithelial cells after invasion by Trichinella spiralis
-
Li, C. K., R. Seth, T. Gray, R. Bayston, Y. R. Mahida, and D. Wakelin. 1998. Production of proinflammatory cytokines and inflammatory mediators in human intestinal epithelial cells after invasion by Trichinella spiralis. Infect. Immun. 66:2200–2206.
-
(1998)
Infect. Immun.
, vol.66
, pp. 2200-2206
-
-
Li, C.K.1
Seth, R.2
Gray, T.3
Bayston, R.4
Mahida, Y.R.5
Wakelin, D.6
-
53
-
-
84940894920
-
Conceptual barriers to understanding physical barriers
-
Lingaraju, A., T. M. Long, Y. Wang, J. R. 2nd Austin, and J. R. Turner. 2015. Conceptual barriers to understanding physical barriers. Semin. Cell Dev. Biol. 42:13–21.
-
(2015)
Semin. Cell Dev. Biol.
, vol.42
, pp. 13-21
-
-
Lingaraju, A.1
Long, T.M.2
Wang, Y.3
Austin, J.R.4
Turner, J.R.5
-
54
-
-
84899672635
-
GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells
-
Lou, G., X. Ma, X. Fu, Z. Meng, W. Zhang, Y. D. Wang, et al. 2014. GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells. PLoS ONE 9:e93567.
-
(2014)
PLoS ONE
, vol.9
-
-
Lou, G.1
Ma, X.2
Fu, X.3
Meng, Z.4
Zhang, W.5
Wang, Y.D.6
-
55
-
-
84883437538
-
Claudins in intestines: distribution and functional significance in health and diseases
-
Lu, Z., L. Ding, Q. Lu, and Y. H. Chen. 2013. Claudins in intestines: distribution and functional significance in health and diseases. Tissue Barriers 1:e24978.
-
(2013)
Tissue Barriers
, vol.1
-
-
Lu, Z.1
Ding, L.2
Lu, Q.3
Chen, Y.H.4
-
56
-
-
84935906852
-
A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment
-
Lu, Z., D. H. Kim, J. Fan, Q. Lu, K. Verbanac, L. Ding, et al. 2015. A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment. Mol. Cancer. 14:120.
-
(2015)
Mol. Cancer.
, vol.14
, pp. 120
-
-
Lu, Z.1
Kim, D.H.2
Fan, J.3
Lu, Q.4
Verbanac, K.5
Ding, L.6
-
57
-
-
84958555991
-
Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation
-
Luettig, J., R. Rosenthal, C. Barmeyer, and J. D. Schulzke. 2015. Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation. Tissue Barriers 3:e977176.
-
(2015)
Tissue Barriers
, vol.3
-
-
Luettig, J.1
Rosenthal, R.2
Barmeyer, C.3
Schulzke, J.D.4
-
58
-
-
0023140596
-
Structural analysis of a human intestinal epithelial cell line
-
Madara, J. L., J. Stafford, K. Dharmsathaphorn, and S. Carlson. 1987. Structural analysis of a human intestinal epithelial cell line. Gastroenterology 92:1133–1145.
-
(1987)
Gastroenterology
, vol.92
, pp. 1133-1145
-
-
Madara, J.L.1
Stafford, J.2
Dharmsathaphorn, K.3
Carlson, S.4
-
59
-
-
77950585581
-
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
-
Marchiando, A. M., L. Shen, W. V. Graham, C. R. Weber, B. T. Schwarz, J. R. 2nd Austin, et al. 2010. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J. Cell Biol. 189:111–126.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 111-126
-
-
Marchiando, A.M.1
Shen, L.2
Graham, W.V.3
Weber, C.R.4
Schwarz, B.T.5
Austin, J.R.6
-
61
-
-
0038617335
-
Functional analysis of tight junctions
-
Matter, K., and M. S. Balda. 2003. Functional analysis of tight junctions. Methods 30:228–234.
-
(2003)
Methods
, vol.30
, pp. 228-234
-
-
Matter, K.1
Balda, M.S.2
-
62
-
-
0018778842
-
Colonic absorption of unconjugated bile acids: perfusion studies in man
-
Mekhjian, H. S., S. F. Phillips, and A. F. Hofmann. 1979. Colonic absorption of unconjugated bile acids: perfusion studies in man. Dig. Dis. Sci. 24:545–550.
-
(1979)
Dig. Dis. Sci.
, vol.24
, pp. 545-550
-
-
Mekhjian, H.S.1
Phillips, S.F.2
Hofmann, A.F.3
-
63
-
-
0015105518
-
Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man
-
Mekjian, H. S., S. F. Phillips, and A. F. Hofmann. 1971. Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man. J. Clin. Investig. 50:1569–1577.
-
(1971)
J. Clin. Investig.
, vol.50
, pp. 1569-1577
-
-
Mekjian, H.S.1
Phillips, S.F.2
Hofmann, A.F.3
-
64
-
-
1842782996
-
Anti-inflammatory properties of pro-inflammatory interferon-gamma
-
Muhl, H., and J. Pfeilschifter. 2003. Anti-inflammatory properties of pro-inflammatory interferon-gamma. Int. Immunopharmacol. 3:1247–1255.
-
(2003)
Int. Immunopharmacol.
, vol.3
, pp. 1247-1255
-
-
Muhl, H.1
Pfeilschifter, J.2
-
65
-
-
2642543244
-
Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells
-
Muhlbauer, M., B. Allard, A. K. Bosserhoff, S. Kiessling, H. Herfarth, G. Rogler, et al. 2004. Differential effects of deoxycholic acid and taurodeoxycholic acid on NF-kappa B signal transduction and IL-8 gene expression in colonic epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 286:G1000–G1008.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.286
, pp. G1000-G1008
-
-
Muhlbauer, M.1
Allard, B.2
Bosserhoff, A.K.3
Kiessling, S.4
Herfarth, H.5
Rogler, G.6
-
66
-
-
35148837743
-
Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies
-
Munch, A., M. Strom, and J. D. Soderholm. 2007. Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies. Scand. J. Gastroenterol. 42:1167–1174.
-
(2007)
Scand. J. Gastroenterol.
, vol.42
, pp. 1167-1174
-
-
Munch, A.1
Strom, M.2
Soderholm, J.D.3
-
67
-
-
79952777720
-
Low levels of bile acids increase bacterial uptake in colonic biopsies from patients with collagenous colitis in remission
-
Munch, A., J. D. Soderholm, A. Ost, A. H. Carlsson, K. E. Magnusson, and M. Strom. 2011. Low levels of bile acids increase bacterial uptake in colonic biopsies from patients with collagenous colitis in remission. Aliment. Pharmacol. Ther. 33:954–960.
-
(2011)
Aliment. Pharmacol. Ther.
, vol.33
, pp. 954-960
-
-
Munch, A.1
Soderholm, J.D.2
Ost, A.3
Carlsson, A.H.4
Magnusson, K.E.5
Strom, M.6
-
68
-
-
0034097798
-
MAP kinase pathways activated by stress: the p38 MAPK pathway
-
Obata, T., G. E. Brown, and M. B. Yaffe. 2000. MAP kinase pathways activated by stress: the p38 MAPK pathway. Crit. Care Med. 28:N67–N77.
-
(2000)
Crit. Care Med.
, vol.28
, pp. N67-N77
-
-
Obata, T.1
Brown, G.E.2
Yaffe, M.B.3
-
69
-
-
84962696177
-
Gastrointestinal mucosal barrier function and diseases
-
Oshima, T., and H. Miwa. 2016. Gastrointestinal mucosal barrier function and diseases. J. Gastroenterol. 51:768–778.
-
(2016)
J. Gastroenterol.
, vol.51
, pp. 768-778
-
-
Oshima, T.1
Miwa, H.2
-
70
-
-
72049127573
-
Recent advances in the understanding of bile acid malabsorption
-
Pattni, S., and J. R. Walters. 2009. Recent advances in the understanding of bile acid malabsorption. Br. Med. Bull. 92:79–93.
-
(2009)
Br. Med. Bull.
, vol.92
, pp. 79-93
-
-
Pattni, S.1
Walters, J.R.2
-
71
-
-
84940787936
-
Systematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence?
-
Pavlidis, P., N. Powell, R. P. Vincent, D. Ehrlich, I. Bjarnason, and B. Hayee. 2015. Systematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence? Aliment. Pharmacol. Ther. 42:802–817.
-
(2015)
Aliment. Pharmacol. Ther.
, vol.42
, pp. 802-817
-
-
Pavlidis, P.1
Powell, N.2
Vincent, R.P.3
Ehrlich, D.4
Bjarnason, I.5
Hayee, B.6
-
72
-
-
84896851032
-
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
-
Peterson, L. W., and D. Artis. 2014. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat. Rev. Immunol. 14:141–153.
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 141-153
-
-
Peterson, L.W.1
Artis, D.2
-
73
-
-
27744551342
-
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
-
Prasad, S., R. Mingrino, K. Kaukinen, K. L. Hayes, R. M. Powell, T. T. MacDonald, et al. 2005. Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. Laboratory investigation; a journal of technical methods and pathology 85:1139–1162.
-
(2005)
Laboratory investigation; a journal of technical methods and pathology
, vol.85
, pp. 1139-1162
-
-
Prasad, S.1
Mingrino, R.2
Kaukinen, K.3
Hayes, K.L.4
Powell, R.M.5
MacDonald, T.T.6
-
74
-
-
42049106193
-
Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation
-
Raimondi, F., P. Santoro, M. V. Barone, S. Pappacoda, M. L. Barretta, M. Nanayakkara, et al. 2008. Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation. Am. J. Physiol. Gastrointest. Liver Physiol. 294:G906–G913.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
, pp. G906-G913
-
-
Raimondi, F.1
Santoro, P.2
Barone, M.V.3
Pappacoda, S.4
Barretta, M.L.5
Nanayakkara, M.6
-
75
-
-
0031761303
-
Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer
-
Rao, R. K. 1998. Acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Alcohol. Clin. Exp. Res. 22:1724–1730.
-
(1998)
Alcohol. Clin. Exp. Res.
, vol.22
, pp. 1724-1730
-
-
Rao, R.K.1
-
76
-
-
67249146480
-
Occludin phosphorylation in regulation of epithelial tight junctions
-
Rao, R. 2009. Occludin phosphorylation in regulation of epithelial tight junctions. Ann. N. Y. Acad. Sci. 1165:62–68.
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1165
, pp. 62-68
-
-
Rao, R.1
-
77
-
-
33244467651
-
Bile salt biotransformations by human intestinal bacteria
-
Ridlon, J. M., D. J. Kang, and P. B. Hylemon. 2006. Bile salt biotransformations by human intestinal bacteria. J. Lipid Res. 47:241–259.
-
(2006)
J. Lipid Res.
, vol.47
, pp. 241-259
-
-
Ridlon, J.M.1
Kang, D.J.2
Hylemon, P.B.3
-
79
-
-
0033635344
-
Complex phenotype of mice lacking occludin, a component of tight junction strands
-
Saitou, M., M. Furuse, H. Sasaki, J. D. Schulzke, M. Fromm, H. Takano, et al. 2000. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol. Biol. Cell 11:4131–4142.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 4131-4142
-
-
Saitou, M.1
Furuse, M.2
Sasaki, H.3
Schulzke, J.D.4
Fromm, M.5
Takano, H.6
-
80
-
-
0027940046
-
Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide
-
Schuerer-Maly, C. C., L. Eckmann, M. F. Kagnoff, M. T. Falco, and F. E. Maly. 1994. Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. Immunology 81:85–91.
-
(1994)
Immunology
, vol.81
, pp. 85-91
-
-
Schuerer-Maly, C.C.1
Eckmann, L.2
Kagnoff, M.F.3
Falco, M.T.4
Maly, F.E.5
-
81
-
-
0036846834
-
Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes
-
Sola, S., M. A. Brito, D. Brites, J. J. Moura, and C. M. Rodrigues. 2002. Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes. Clin. Sci. (Lond.) 103:475–485.
-
(2002)
Clin. Sci. (Lond.)
, vol.103
, pp. 475-485
-
-
Sola, S.1
Brito, M.A.2
Brites, D.3
Moura, J.J.4
Rodrigues, C.M.5
-
82
-
-
1242272826
-
Inhibition of nitric oxide synthesis potentiates the colonic permeability increase triggered by luminal bile acids
-
Sun, Y., B. M. Fihn, M. Jodal, and H. Sjovall. 2004a. Inhibition of nitric oxide synthesis potentiates the colonic permeability increase triggered by luminal bile acids. Acta Physiol. Scand. 180:167–175.
-
(2004)
Acta Physiol. Scand.
, vol.180
, pp. 167-175
-
-
Sun, Y.1
Fihn, B.M.2
Jodal, M.3
Sjovall, H.4
-
83
-
-
1242295305
-
Enteric neurones modulate the colonic permeability response to luminal bile acids in rat colon in vivo
-
Sun, Y., B. M. Fihn, H. Sjovall, and M. Jodal. 2004b. Enteric neurones modulate the colonic permeability response to luminal bile acids in rat colon in vivo. Gut 53:362–367.
-
(2004)
Gut
, vol.53
, pp. 362-367
-
-
Sun, Y.1
Fihn, B.M.2
Sjovall, H.3
Jodal, M.4
-
84
-
-
77950462401
-
Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats
-
Suzuki, T., and H. Hara. 2010. Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats. Nutrition Metabolism 7:19.
-
(2010)
Nutrition Metabolism
, vol.7
, pp. 19
-
-
Suzuki, T.1
Hara, H.2
-
85
-
-
84941349580
-
Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice
-
Tanaka, H., M. Takechi, H. Kiyonari, G. Shioi, A. Tamura, and S. Tsukita. 2015. Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice. Gut 64:1529–1538.
-
(2015)
Gut
, vol.64
, pp. 1529-1538
-
-
Tanaka, H.1
Takechi, M.2
Kiyonari, H.3
Shioi, G.4
Tamura, A.5
Tsukita, S.6
-
86
-
-
33645963995
-
Claudins and epithelial paracellular transport
-
Van Itallie, C. M., and J. M. Anderson. 2006. Claudins and epithelial paracellular transport. Annu. Rev. Physiol. 68:403–429.
-
(2006)
Annu. Rev. Physiol.
, vol.68
, pp. 403-429
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
87
-
-
84912092373
-
Architecture of tight junctions and principles of molecular composition
-
Van Itallie, C. M., and J. M. Anderson. 2014. Architecture of tight junctions and principles of molecular composition. Semin. Cell Dev. Biol. 36:157–165.
-
(2014)
Semin. Cell Dev. Biol.
, vol.36
, pp. 157-165
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
88
-
-
0242665742
-
Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins
-
Van Itallie, C. M., A. S. Fanning, and J. M. Anderson. 2003. Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins. Am. J. Physiol. Renal Physiol. 285:F1078–F1084.
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.285
, pp. F1078-F1084
-
-
Van Itallie, C.M.1
Fanning, A.S.2
Anderson, J.M.3
-
89
-
-
58549113342
-
Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea
-
Viswanathan, V. K., K. Hodges, and G. Hecht. 2009. Enteric infection meets intestinal function: how bacterial pathogens cause diarrhoea. Nat. Rev. Microbiol. 7:110–119.
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 110-119
-
-
Viswanathan, V.K.1
Hodges, K.2
Hecht, G.3
-
90
-
-
84927738000
-
Bile acid malabsorption in inflammatory bowel disease
-
Vitek, L. 2015. Bile acid malabsorption in inflammatory bowel disease. Inflamm. Bowel Dis. 21:476–483.
-
(2015)
Inflamm. Bowel Dis.
, vol.21
, pp. 476-483
-
-
Vitek, L.1
-
91
-
-
84880136128
-
The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon
-
Ward, J. B., M. S. Mroz, and S. J. Keely. 2013. The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon. Neurogastroenterol. Motil. 25:708–711.
-
(2013)
Neurogastroenterol. Motil.
, vol.25
, pp. 708-711
-
-
Ward, J.B.1
Mroz, M.S.2
Keely, S.J.3
-
93
-
-
36849042673
-
Opposing regulation of the tight junction protein claudin-2 by interferon-gamma and interleukin-4
-
Wisner, D. M., L. R. 3rd Harris, C. L. Green, and L. S. Poritz. 2008. Opposing regulation of the tight junction protein claudin-2 by interferon-gamma and interleukin-4. J. Surg. Res. 144:1–7.
-
(2008)
J. Surg. Res.
, vol.144
, pp. 1-7
-
-
Wisner, D.M.1
Harris, L.R.2
Green, C.L.3
Poritz, L.S.4
-
94
-
-
0036305854
-
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
-
Zolotarevsky, Y., G. Hecht, A. Koutsouris, D. E. Gonzalez, C. Quan, J. Tom, et al. 2002. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123:163–172.
-
(2002)
Gastroenterology
, vol.123
, pp. 163-172
-
-
Zolotarevsky, Y.1
Hecht, G.2
Koutsouris, A.3
Gonzalez, D.E.4
Quan, C.5
Tom, J.6
|